Searched for: department%3A%22Intelligent%255C%252BSystems%22
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Zhang, S. (author), Hanjalic, A. (author), Wang, H. (author)
Nodal spreading influence is the capability of a node to activate the rest of the network when it is the seed of spreading. Combining nodal properties (centrality metrics) derived from local and global topological information respectively has been shown to better predict nodal influence than using a single metric. In this work, we investigate...
journal article 2024
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Baker, Emily (author), Leonenko, Ganna (author), Schmidt, Karl Michael (author), Hill, Matthew (author), Myers, Amanda J. (author), Shoai, Maryam (author), de Rojas, Itziar (author), Tesi, N. (author), Holstege, H. (author)
Introduction Both late-onset Alzheimer’s disease (AD) and ageing have a strong genetic component. In each case, many associated variants have been discovered, but how much missing heritability remains to be discovered is debated. Variability in the estimation of SNP-based heritability could explain the differences in reported heritability....
journal article 2023
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Li, Meng (author), Chen, Yifei (author), Zhu, Liehaung (author), Zhang, Zijian (author), Ni, Jianbing (author), Lal, C. (author), Conti, M. (author)
Many regions are in urgent need of facial masks for slowing down the spread of COVID-19. To fight the pandemic, people are contributing masks through donation systems. Most existing systems are built on a centralized architecture which is prone to the single point of failure and lack of transparency. Blockchain-based solutions neglect...
journal article 2023
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Fleres, Antonio (author), Veling, Louise (author), Broz, F. (author), Damiano, Luisa (author)
In the original publication of this article, the affiliation information of two authors was inadvertently published incorrectly. Please find the correct affiliation information below: Antonio Fleres 1PhD School for Communication Studies, IULM University, via Carlo Bo 1, 20143 Milan, Italy Luisa Damiano 4Department of Communication, Arts and...
journal article 2023
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Zhang, M. (author), Bouland, G.A. (author), Holstege, H. (author), Reinders, M.J.T. (author)
Background and Objectives - With age, somatic mutations accumulated in human brain cells can lead to various neurologic disorders and brain tumors. Because the incidence rate of Alzheimer disease (AD) increases exponentially with age, investigating the association between AD and the accumulation of somatic mutation can help understand the...
journal article 2023
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Fleres, Antonio (author), Veling, Louise (author), Broz, F. (author), Damiano, Luisa (author)
This article proposes an integrative approach to robotics research, based on bringing interdisciplinarity into the lab. Such an approach will facilitate researchers across various fields in gaining a more nuanced understanding of technology, how it is developed, and its potential impacts. We describe how a philosopher spent time embedded in...
journal article 2023
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Sharma, Bhawana (author), Sharma, Lokesh (author), Lal, C. (author), Roy, Satyabrata (author)
Internet of Things (IoT) applications are growing in popularity for being widely used in many real-world services. In an IoT ecosystem, many devices are connected with each other via internet, making IoT networks more vulnerable to various types of cyber attacks, thus a major concern in its deployment is network security and user privacy. To...
journal article 2023
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Zhang, T. (author), El Ali, Abdallah (author), Wang, Chen (author), Hanjalic, A. (author), Cesar, Pablo (author)
Instead of predicting just one emotion for one activity (e.g., video watching), fine-grained emotion recognition enables more temporally precise recognition. Previous works on fine-grained emotion recognition require segment-by-segment, fine-grained emotion labels to train the recognition algorithm. However, experiments to collect these...
journal article 2023
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Zou, L. (author), Zhan, Xiu xiu (author), Sun, Jie (author), Hanjalic, A. (author), Wang, H. (author)
Temporal networks refer to networks like physical contact networks whose topology changes over time. Predicting future temporal network is crucial e.g., to forecast the epidemics. Existing prediction methods are either relatively accurate but black-box, or white-box but less accurate. The lack of interpretable and accurate prediction methods...
journal article 2022
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van Bree, Elisabeth J. (author), Guimarães, Rita L.F.P. (author), Lundberg, Mischa (author), Blujdea, Elena R. (author), Rosenkrantz, Jimi L. (author), White, Fred T.G. (author), Reinders, M.J.T. (author), Holstege, H. (author), Jacobs, Frank M.J. (author)
Genome-wide association studies (GWAS) have been highly informative in discovering disease-associated loci but are not designed to capture all structural variations in the human genome. Using long-read sequencing data, we discovered widespread structural variation within SINE-VNTR-Alu (SVA) elements, a class of great ape-specific transposable...
journal article 2022
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van der Lee, S.J. (author), De Rojas, I. (author), Holstege, H. (author), Hulsman, M. (author), Reinders, M.J.T. (author), Tesi, N. (author), van Rooij, Jeroen (author), Zhao, Y. (author), Zhang, X. (author)
Characterization of the genetic landscape of Alzheimer’s disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage<br/>genome-wide association study totaling 111,326 clinically diagnosed/‘proxy’ AD cases and 677,663 controls. We found...
journal article 2022
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Fernández Robledo, O. (author), Zhan, X. (author), Hanjalic, A. (author), Wang, H. (author)
Multiple network embedding algorithms have been proposed to perform the prediction of missing or future links in complex networks. However, we lack the understanding of how network topology affects their performance, or which algorithms are more likely to perform better given the topological properties of the network. In this paper, we...
journal article 2022
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Das, B. (author), Hanjalic, A. (author), Isufi, E. (author)
Data processing over graphs is usually done on graphs of fixed size. However, graphs often grow with new nodes arriving over time. Knowing the connectivity information of these nodes, and thus, the expanded graph is crucial for processing data over the expanded graph. In its absence, its inference and the subsequent data processing become...
journal article 2022
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Holstege, H. (author), Hulsman, M.J. (author), Charbonnier, Camille (author), Grenier-Boley, Banjamin (author), Quenez, Olivier (author), Grozeva, Detelina (author), van Rooij, Jeroen G.J. (author), Reinders, M.J.T. (author), van der Lee, S.J. (author)
Alzheimer’s disease (AD), the leading cause of dementia, has an estimated<br/>heritability of approximately 70%1. The genetic component of AD has been mainly assessed using genome-wide association studies, which do not capture the risk contributed by rare variants2. Here, we compared the gene-based burden of rare damaging variants in exome...
journal article 2022
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Xu, Xing (author), Lin, Kaiyi (author), Yang, Yang (author), Hanjalic, A. (author), Shen, Heng Tao (author)
Recently, generative adversarial network (GAN) has shown its strong ability on modeling data distribution via adversarial learning. Cross-modal GAN, which attempts to utilize the power of GAN to model the cross-modal joint distribution and to learn compatible cross-modal features, is becoming the research hotspot. However, the existing cross...
journal article 2022
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Mol, Merel O. (author), van der Lee, S.J. (author), Hulsman, M. (author), Pijnenburg, Yolande A.L. (author), Scheltens, Phillip (author), Seelaar, Harro (author), van Swieten, John C. (author), Kaat, Laura Donker (author), Holstege, H. (author), van Rooij, Jeroen G.J. (author)
Background: Many families with clinical early-onset Alzheimer’s disease (EOAD) remain genetically unexplained. A combination of genetic factors is not standardly investigated. In addition to monogenic causes, we evaluated the possible polygenic architecture in a large series of families, to assess if genetic testing of familial EOAD could be...
journal article 2022
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Zhang, M. (author), Ganz, Andrea B. (author), Rohde, Susan (author), Rozemuller, Annemieke J.M. (author), Bank, Netherlands Brain (author), Reinders, M.J.T. (author), Scheltens, Philip (author), Hulsman, M. (author), Hoozemans, Jeroen J.M. (author), Holstege, H. (author)
Introduction: With increasing age, neuropathological substrates associated with Alzheimer's disease (AD) accumulate in brains of cognitively healthy individuals—are they resilient, or resistant to AD-associated neuropathologies?. Methods: In 85 centenarian brains, we correlated NIA (amyloid) stages, Braak (neurofibrillary tangle) stages, and...
journal article 2022
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Li, Meng (author), Chen, Yifei (author), Lal, C. (author), Conti, M. (author), Martinelli, Fabio (author), Alazab, Mamoun (author)
Security and privacy issues have become a major hindrance to the broad adoption of Ride-Hailing Services (RHSs). In this article, we introduce a new collusion attack initiated by the Ride-Hailing Service Provider (RHSP) and a driver that could easily link the real riders and their anonymous requests (credentials). Besides this attack,...
journal article 2022
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Zhang, T. (author), El Ali, Abdallah (author), Hanjalic, A. (author), Cesar, Pablo (author)
Fine-grained emotion recognition can model the temporal dynamics of emotions, which is more precise than predicting one emotion retrospectively for an activity (e.g., video clip watching). Previous works require large amounts of continuously annotated data to train an accurate recognition model, however experiments to collect such large...
journal article 2022
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Tesi, N. (author), van der Lee, S.J. (author), Hulsman, M. (author), Holstege, H. (author), Reinders, M.J.T. (author)
Genetic association studies are frequently used to study the genetic basis of numerous human phenotypes. However, the rapid interrogation of how well a certain genomic region associates across traits as well as the interpretation of genetic associations is often complex and requires the integration of multiple sources of annotation, which...
journal article 2021
Searched for: department%3A%22Intelligent%255C%252BSystems%22
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