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Ontology-based Malaria Parasite Stage and Species Identification from Peripheral Blood Smear Images

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MS-28.601.pdf (472.3 KB)

These file attachments have been under embargo and were made available to the public after the embargo was lifted on 16 September 2011.

Author: Makkapati, V. · Rao, R. (US Army Research Laboratory)
Type:Conference paper
Date:2011-09-16
Embargo lifted:2011-09-16
Publisher: IEEE
Institution: Philips Research
Source:EMBC 2011: 33rd Annual International Conference of tje IEEE Engineering in Medicine and Biology Society, Boston, USA, 30 August - 3 September 2011; authors version
Identifier:MS 28.601
Keywords: chromatin dots segmentation · cytoplasm segmentation · malaria diagnosis · species identification
Rights: (c) IEEE

The diagnosis and treatment of malaria infection requires detectingthe presence of malaria parasite in the patient as well as identification of the parasite species. We present an image processing-basedapproach to detect parasites in microscope images of blood smear andan ontology-based classification of the stage of the parasite for identifying the species of infection. This approach is patterned after the diagnosis approach adopted by a pathologist for visual examination and hence is expected to deliver similar results. We formulateseveral rules based on the morphology of the basic components of a parasite namely chromatin dot(s) and cytoplasm to identify parasite stage and species. Numerical results are presented for data taken from various patients. Sensitivity of 88% and specificity of 95% is reported by evaluation of the scheme on 55 images.

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