Analysis and compensation for the effect of the catheter position on image intensities in intravascular optical coherence tomography

Analysis and compensation for the effect of the catheter position on image intensities in intravascular optical coherence tomography

Liu, Shengnan (Leiden University Medical Center)
Eggermont, Jeroen (Leiden University Medical Center)
Wolterbeek, Ron (Leiden University Medical Center)
Broersen, Alexander (Leiden University Medical Center)
Busk, Carol A.G.R. (University of Southern Denmark)
Precht, Helle (University College Lillebælt)
Lelieveldt, B.P.F. (TU Delft Pattern Recognition and Bioinformatics; Leiden University Medical Center)
Dijkstra, J. (Leiden University Medical Center)

2016

Intravascular optical coherence tomography (IVOCT) is an imaging technique that is used to analyze the underlying cause of cardiovascular disease. Because a catheter is used during imaging, the intensities can be affected by the catheter position. This work aims to analyze the effect of the catheter position on IVOCT image intensities and to propose a compensation method to minimize this effect in order to improve the visualization and the automatic analysis of IVOCT images. The effect of catheter position is modeled with respect to the distance between the catheter and the arterial wall (distance-dependent factor) and the incident angle onto the arterial wall (angle-dependent factor). A light transmission model incorporating both factors is introduced. On the basis of this model, the interaction effect of both factors is estimated with a hierarchical multivariant linear regression model. Statistical analysis shows that IVOCT intensities are significantly affected by both factors with p<0.001, as either aspect increases the intensity decreases. This effect differs for different pullbacks. The regression results were used to compensate for this effect. Experiments show that the proposed compensation method can improve the performance of the automatic bioresorbable vascular scaffold strut detection.

angle-dependency of near-infrared light
backscattered intensity
distance-dependency of near-infrared
hierarchical linear regression
intracoronary optical coherence tomography
Intravascular optical coherence tomography

http://resolver.tudelft.nl/uuid:320a952f-7328-4449-90b3-8111ea4b9ad5

https://doi.org/10.1117/1.JBO.21.12.126005

1083-3668

Journal of Biomedical Optics, 21 (12), 1-10

Institutional Repository

journal article

© 2016 Shengnan Liu, Jeroen Eggermont, Ron Wolterbeek, Alexander Broersen, Carol A.G.R. Busk, Helle Precht, B.P.F. Lelieveldt, J. Dijkstra