Print Email Facebook Twitter Design of a mechanical loading device for studying the load dependent transport of solutes across articular cartilage in a micro-CT chamber Title Design of a mechanical loading device for studying the load dependent transport of solutes across articular cartilage in a micro-CT chamber Author Glynou, A. Contributor Weinans, H.H. (mentor) Faculty Mechanical, Maritime and Materials Engineering Department BioMechanical Engineering Programme BME Date 2014-10-23 Abstract The present project focused on the design and development of a mechanical loading device that allows the convection studies in cartilage within a micro-CT chamber. A plastic-made device was designed and build in order to ensure the successful operation in the micro-CT. Besides that it allowed the monitoring of the tissue material properties by incorporating a load cell. The later experimental procedure indicated that 10% compression seems to have a beneficial effect on the solutes penetration across articular cartilage. Therefore a clinically applicable tool was developed that includes the convection in a diagnostic method for the first time Subject articular cartilageCECTmechanical loading deviceconvection To reference this document use: http://resolver.tudelft.nl/uuid:342396e2-e530-4ae7-8b24-c65718794c62 Embargo date 2015-11-06 Part of collection Student theses Document type master thesis Rights (c) 2014 Glynou, A. Files PDF Thesis_Mina_Glynou.pdf 2.43 MB Close viewer /islandora/object/uuid:342396e2-e530-4ae7-8b24-c65718794c62/datastream/OBJ/view