Print Email Facebook Twitter High Frame Rate Volumetric Imaging of Microbubbles Using a Sparse Array and Spatial Coherence Beamforming Title High Frame Rate Volumetric Imaging of Microbubbles Using a Sparse Array and Spatial Coherence Beamforming Author Wei, Luxi (Erasmus MC) Wahyulaksana, G. (Erasmus MC) Meijlink, Bram (Erasmus MC) Ramalli, Alessandro (University of Florence) Noothout, E.C. (TU Delft ImPhys/Medical Imaging) Verweij, M.D. (TU Delft ImPhys/Medical Imaging) van der Steen, A.F.W. (TU Delft ImPhys/Medical Imaging; Erasmus MC) de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC) Vos, H.J. (TU Delft ImPhys/Medical Imaging; Erasmus MC) Date 2021 Abstract Volumetric ultrasound imaging of blood flow with microbubbles enables a more complete visualization of the microvasculature. Sparse arrays are ideal candidates to perform volumetric imaging at reduced manufacturing complexity and cable count. However, due to the small number of transducer elements, sparse arrays often come with high clutter levels, especially when wide beams are transmitted to increase the frame rate. In this study, we demonstrate with a prototype sparse array probe and a diverging wave transmission strategy, that a uniform transmission field can be achieved. With the implementation of a spatial coherence beamformer, the background clutter signal can be effectively suppressed, leading to a signal to background ratio improvement of 25 dB. With this approach, we demonstrate the volumetric visualization of single microbubbles in a tissue-mimicking phantom as well as vasculature mapping in a live chicken embryo chorioallantoic membrane. Subject Array signal processingClutterCoherence beamforminghigh frame rateImagingmicrobubblesSignal to noise ratiosparse arraySpatial coherenceSpiralsUltrasonic imagingvolumetric imaging To reference this document use: http://resolver.tudelft.nl/uuid:37c1595e-53dc-4464-a792-04332d12ab6e DOI https://doi.org/10.1109/TUFFC.2021.3086597 ISSN 0885-3010 Source IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control, 68 (10), 3069-3081 Part of collection Institutional Repository Document type journal article Rights © 2021 Luxi Wei, G. Wahyulaksana, Bram Meijlink, Alessandro Ramalli, E.C. Noothout, M.D. Verweij, A.F.W. van der Steen, N. de Jong, H.J. Vos, More Authors Files PDF 09446938.pdf 2.64 MB Close viewer /islandora/object/uuid:37c1595e-53dc-4464-a792-04332d12ab6e/datastream/OBJ/view