Adsorption of molybdenum on Zr-based MOFs for potential application in the ⁹⁹Mo/^99mTc generator

Adsorption of molybdenum on Zr-based MOFs for potential application in the ⁹⁹Mo/^99mTc generator

Ma, C. (TU Delft RST/Applied Radiation & Isotopes)
Vasileiadis, A. (TU Delft RST/Storage of Electrochemical Energy)
Wolterbeek, H.T. (TU Delft RST/Applied Radiation & Isotopes)
Denkova, A.G. (TU Delft RST/Applied Radiation & Isotopes)
Serra Crespo, P. (TU Delft RST/Applied Radiation & Isotopes)

2021

The potential of the metal–organic framework UiO-66 and its functionalized derivatives for their utilization in the ⁹⁹Mo/^99mTc generator was assessed. Molybdenum adsorption experiments, structure characterization, molecular simulations and column experiments with molybdenum-99 were carried out. The results showed that the maximum molybdenum adsorption capacity achieved for UiO-66 was 335 mg g⁻¹. Adsorption on the surface of the UiO-66 occurs via electrostatic interaction and DFT calculations verified the enhanced affinity between the adsorbents and the molybdenum ions by Zr-O-Mo coordination, anion-π as well as hydrogen bonds. In addition, the performance of a ⁹⁹Mo/^99mTc generator fabricated with Form-UiO-66 was evaluated. The results showed that adsorption was comparable with the experiments using non-active molybdenum and that the ^99mTc elution efficiency of around 70% could be achieved without zirconium breakthrough.

Mo/Tc generator
Density functional theory
Interaction mechanism
Molybdenum adsorption
UiO-66

http://resolver.tudelft.nl/uuid:d84c1af2-cb72-451b-a42c-c250a9f40ac3

https://doi.org/10.1016/j.apsusc.2021.151340

0169-4332

Applied Surface Science, 572

Institutional Repository

journal article

© 2021 C. Ma, A. Vasileiadis, H.T. Wolterbeek, A.G. Denkova, P. Serra Crespo