Print Email Facebook Twitter Miniaturization of Process Analytical Technology: from Concept to Reality Title Miniaturization of Process Analytical Technology: from Concept to Reality Author Neves Sao Pedro, M. (TU Delft BT/Bioprocess Engineering) Contributor Ottens, M. (promotor) Eppink, M. (promotor) Degree granting institution Delft University of Technology Corporate name Delft University of Technology Date 2023-10-27 Abstract Continuous biomanufacturing is considered the future phase for the optimization of production processes in the biopharmaceutical industry. Productivity, product quality and consistency are greatly improved while production costs and environmental footprint are drastically reduced. The manufacturing of monoclonal antibodies (mAbs), an important biopharmaceutical in the treatment of cancers, autoimmune disorders, and, more recently, COVID-19, is eligible for this continuous processing due to patent expiration and the subsequent need to lower manufacturing costs... Subject Antibody aggregationContinuous BiomanufacturingProcess Analytical Technology (PAT)Microfluidic SensorFluorescent Dyes To reference this document use: https://doi.org/10.4233/uuid:ec3f81c3-1bb4-4724-9f97-fff46e3c1c66 ISBN 978-94-6384-473-4 Embargo date 2023-09-27 Part of collection Institutional Repository Document type doctoral thesis Rights © 2023 M. Neves Sao Pedro Files PDF Thesis_Miniaturization_of_PAT.pdf 7.73 MB Close viewer /islandora/object/uuid:ec3f81c3-1bb4-4724-9f97-fff46e3c1c66/datastream/OBJ/view