Print Email Facebook Twitter Impetiginized dyshidrotic eczema Title Impetiginized dyshidrotic eczema Author Tchernev, Georgi (Medical Institute of Ministry of Interior (MVR)) Zanardelli, Matteo (Pharmacology, Toxicology and Innovative Treatments Department, Italy) Voicu, Cristiana (Polisano Clinic) Bakardzhiev, Ilko (Medical University of Varna) Lotti, T. (TU Delft BT/Environmental Biotechnology; Sapienza-University of Rome) Lotti, Jacopo (Sapienza-University of Rome) França, Katlein (University of Miami Miller School of Medicine) Batashki, Atanas (Medical University of Plovdiv) Wollina, Uwe (Academic Teaching Hospital Dresden-Friedrichstadt) Date 2017 Abstract A 16 years old female patient, affected by atopic dermatitis and rhinoconjunctivitis allergica since childhood, requested a dermatologic consultation for lesions which had appeared after 3 months of local treatment with clobethasole propionate. The histological analysis confirmed the diagnosis of dyshidrotic eczema and the microbiological smears demonstrated a significant infection with Staphylococcus aureus. The risk of developing corticosteroids’ side-effects depends on the potency of the product, extended period of use and the volume of product applied. Clobetasol propionate is a group I- highly potent corticosteroid, which should be used for a maximum period of 2 weeks. Several authors have found that this agent has cumulative depot effect, persisting in the epidermis for 4 days after only one application. Taking together these observations, sustained by the clinical case presented above, we can conclude that the infectious risks associated with topical corticosteroid treatment must not be neglected, particularly since treated patients are fragile, and frequently have multiple well-known risk factors. Subject AureusClobetasolHand dermatitisSkin barrierStSuperinfections To reference this document use: http://resolver.tudelft.nl/uuid:f238d051-0e28-4ef5-8e78-d32598bb999d DOI https://doi.org/10.3889/oamjms.2017.081 Source Open Access Macedonian Journal of Medical Sciences, 5 (4 Special Issue GlobalDermatology), 539-540 Part of collection Institutional Repository Document type journal article Rights © 2017 Georgi Tchernev, Matteo Zanardelli, Cristiana Voicu, Ilko Bakardzhiev, T. Lotti, Jacopo Lotti, Katlein França, Atanas Batashki, Uwe Wollina Files PDF 1184_3976_1_PB.pdf 320.29 KB Close viewer /islandora/object/uuid:f238d051-0e28-4ef5-8e78-d32598bb999d/datastream/OBJ/view