Fibroepithelioma of Pinkus (FeP) located in the left lower quadrant of the abdomen - Case Report and review of the literature

Fibroepithelioma of Pinkus (FeP) located in the left lower quadrant of the abdomen - Case Report and review of the literature

Mihai, Mara Madalina (Carol Davila University of Medicine and Pharmacy)
Voicu, Cristiana (Polisano Clinic)
Lupu, Mihai (Medas Medical Centre)
Koleva, Nely (Medical Institute of Ministry of Interior (MVR))
Patterson, James W. (University of Virginia Health System)
Lotti, T. (TU Delft BT/Environmental Biotechnology; Sapienza-University of Rome)
Lotti, Jacopo (Sapienza-University of Rome)
França, Katlein (University of Miami Miller School of Medicine)
Batashki, Atanas (Medical University of Plovdiv)
Bakardzhiev, Ilko (Medical University of Varna)
Wollina, Uwe (Academic Teaching Hospital Dresden-Friedrichstadt)
Tchernev, Georgi (Medical Institute of Ministry of Interior (MVR); Venereology and Dermatologic Surgery)

2017

Background: Fibroepithelioma of Pinkus (FeP) is an uncommon and controversial skin lesion, sharing features of both basal cell carcinoma (BCC) and trichoepithelioma. In this article, we present a case of FeP and synthesise current concepts on the etiopathogenesis, diagnosis and treatment of this uncommon tumour. Case Report: We report the case of an 88-year-old male patient presenting to the dermatology clinic for a sharply demarcated, pink, exophytic cutaneous tumour situated in the left inguinal region. The histopathological examination performed after complete surgical excision of the lesion revealed a diagnosis of FeP. A systematic review of the literature was conducted. The terms 'fibroepithelioma' and 'Pinkus' have been searched in bibliographical databases, including PubMed and Google Scholar, without time limitation up to February 15th, 2017. Seventy-nine articles that fulfilled all the required conditions were identified. Relevant citations and additional articles identified from references have been assessed. The systematic review included a total number of 452 cases of FeP. Conclusion: Even though FeP is considered a relatively rare tumour, its true incidence rate might be higher than previously believed. The clinical aspects of the lesion described in this paper and its location in the left lower quadrant of the abdomen are classic features of FeP. Histopathologic examination revealed features of both BCC and trichoepithelioma. Further epidemiological studies are required to clarify whether patients with FEP should be screened for the occurrence of other malignancies.

Basal cell carcinoma
Fibroepithelioma of Pinkus
Trichoblastoma
Trichoepithelioma

http://resolver.tudelft.nl/uuid:fa64da3c-1bf0-45ca-b126-376514b5f1b9

https://doi.org/10.3889/oamjms.2017.079

Open Access Macedonian Journal of Medical Sciences, 5 (4 Special Issue GlobalDermatology), 439-444

Institutional Repository

review

© 2017 Mara Madalina Mihai, Cristiana Voicu, Mihai Lupu, Nely Koleva, James W. Patterson, T. Lotti, Jacopo Lotti, Katlein França, Atanas Batashki, Ilko Bakardzhiev, Uwe Wollina, Georgi Tchernev