Late onset achromatic melanoma arising in a giant congenital melanocytic nevus

Late onset achromatic melanoma arising in a giant congenital melanocytic nevus

Tchernev, Georgi (Medical Institute of Ministry of Interior (MVR))
Patterson, James W. (University of Virginia Health System)
Bakardzhiev, Ilko (Medical University of Varna)
Lotti, T. (TU Delft BT/Environmental Biotechnology)
Lotti, Jacopo (Sapienza-University of Rome)
França, Katlein (University of Miami Miller School of Medicine)
Batashki, Atanas (Medical University of Plovdiv)
Wollina, Uwe (Academic Teaching Hospital Dresden-Friedrichstadt)

2017

A 61-year-old woman, with a lifelong history of a giant congenital melanocytic nevus in the occipital region with secondary development of giant melanoma is presented. Surgical excision was performed, and the histopathological evaluation confirmed the diagnosis of Giant Malignant Melanoma (GMM) with a maximum tumour thickness of 16 mm. Nowadays, there is tremendous uncertainty regarding how giant congenital melanocytic nevi (GCMN) should be treated. The standard approach to patients with late onset giant congenital melanocytic nevi (GCMN is based on two main considerations: (1) obtain an acceptable cosmetic results with the purpose to decrease the psychosocial inconvenience to each patient, and (2) to attempt to minimise the risk of development of malignant transformation. Unfortunately complete surgical removal of the GCMN is usually difficult and very often impossible without subsequent functional or cosmetic mutilations.

Congenital nevus
Melanoma
Outcome
Prevention
Progression
Surgery

http://resolver.tudelft.nl/uuid:87e2b109-0a5b-4874-b8d1-8615eb7e74a8

https://doi.org/10.3889/oamjms.2017.077

Open Access Macedonian Journal of Medical Sciences, 5 (4 Special Issue GlobalDermatology), 533-534

Institutional Repository

journal article

© 2017 Georgi Tchernev, James W. Patterson, Ilko Bakardzhiev, T. Lotti, Jacopo Lotti, Katlein França, Atanas Batashki, Uwe Wollina