Print Email Facebook Twitter A compact multi-electrode system to measure in vivo electrical activity in the olivocerebellar system Title A compact multi-electrode system to measure in vivo electrical activity in the olivocerebellar system: Measuring sub-threshold oscillations and action potentials spatially and over time Author Weskin, M.E. Contributor Serdijn, W.A. (mentor) Faculty Electrical Engineering, Mathematics and Computer Science Department Electrical Engineering Programme Bio-Electronics Date 2016-08-26 Abstract In the Erasmus Medical Center (Erasmus MC) in Rotterdam a lot of research is done to investigate the olivocerebellar system, consisting of the cerebellum (motor behaviour) and the inferior olive (sensory input). The correlation and propagation of signals between both parts are of interest when investigating the influence of sensory input on the motor behaviour. To facilitate this research, a compact system to measure in vivo electrical neural activity in the olivocerebellar system spatially and over time is designed and described in this work. The designed system consists of three subdesigns: electrodes, electronics and a measurement set-up. It is small, compact and capable of measuring in vivo neural activity. The Delft Electrode Array proves its concept with four robustly mounted electrode tips, however the number of mounted electrodes should be increased. The Delft Analogue Front End, the electronics system with its custom measurement set-up, can - after only changing software parameters - measure up to 32 channels. Its bandwidth (-3 dB bandwidth from 0.3Hz to 30 kHz) is wide enough to measure sub-threshold oscillations (1 to 10Hz) as well as action potentials (up to 10 kHz). To reference this document use: uuid:d9afbb3e-ca3f-47f1-b701-1cc700fb75f3 Embargo date 2021-08-26 Part of collection Student theses Document type master thesis Rights (c) 2016 Weskin, M.E.