Searched for:
(1 - 20 of 389)

Pages

document
Dekker, Lennart (author)
Gouda deals with land subsidence and groundwater problems. A solution to these challenges is the application of Drainage-Infiltration-Transport (DIT) sewers, on which research is lacking. This thesis provides provides infiltration and drainage capacity values on DIT sewers and helps to understand the governing processes.
master thesis 2019
document
Dekker, Else (author)
As material stocks are depleting and the building sector plays a big role in using these materials a circular economy can bring a solution to this depleting problem. Within the thoughts of applying the circular economy to the built environment, upscaling would not be possible without the community to engage to the topic. This project of a...
master thesis 2019
document
Kabiri, Y. (author), Angelin, Alessandro (author), Ahmed, Ishtiaq (author), Mutlu, Hatice (author), Bauer, Jens (author), Niemeyer, Christof M. (author), Zandbergen, H.W. (author), Dekker, C. (author)
Staining compounds containing heavy elements (electron dyes) can facilitate the visualization of DNA and related biomolecules by using TEM. However, research into the synthesis and utilization of alternative electron dyes has been limited. Here, we report the synthesis of a novel DNA intercalator molecule, bis-acridine uranyl (BAU). NMR...
journal article 2019
document
Bracher, J.M. (author), Martinez-Rodriguez, Oscar A. (author), Dekker, W.J.C. (author), Verhoeven, M.D. (author), van Maris, A.J.A. (author), Pronk, J.T. (author)
Expression of a heterologous xylose isomerase, deletion of the GRE3 aldose-reductase gene and overexpression of genes encoding xylulokinase (XKS1) and non-oxidative pentose-phosphate-pathway enzymes (RKI1, RPE1, TAL1, TKL1) enables aerobic growth of Saccharomyces cerevisiae on d-xylose. However, literature reports differ on whether anaerobic...
journal article 2019
document
Kabiri, Y. (author), Ravelli, Raimond B.G. (author), Lehnert, Tibor (author), Qi, Haoyuan (author), Katan, A.J. (author), Roest, Natascha (author), Kaiser, Ute (author), Dekker, C. (author), Peters, Peter J. (author), Zandbergen, H.W. (author)
Over the last few years, tremendous progress has been made in visualizing biologically important macromolecules using transmission electron microscopy (TEM) and understanding their structure-function relation. Yet, despite the importance of DNA in all forms of life, TEM visualization of individual DNA molecules in its native unlabeled form...
journal article 2019
document
Wu, Fabai (author), Japaridze, A. (author), Zheng, X.Z. (author), Wiktor, J.M. (author), Kerssemakers, J.W.J. (author), Dekker, C. (author)
Although the physical properties of chromosomes, including their morphology, mechanics, and dynamics are crucial for their biological function, many basic questions remain unresolved. Here we directly image the circular chromosome in live E. coli with a broadened cell shape. We find that it exhibits a torus topology with, on average, a lower...
journal article 2019
document
Fragasso, A. (author), Pud, S. (author), Dekker, C. (author)
The performance of solid-state nanopores as promising biosensors is severely hampered by low-frequency 1/f noise in the through-pore ionic current recordings. Here, we develop a model for the 1/f noise in such nanopores, that, unlike previous reports, accounts for contributions from both the pore-cylinder, pore-surface, and access regions. To...
journal article 2019
document
Zhao, Shidi (author), Restrepo Perez, L. (author), Soskine, Misha (author), Maglia, Giovanni (author), Joo, C. (author), Dekker, C. (author), Aksimentiev, A. (author)
Ion channels form the basis of information processing in living cells by facilitating the exchange of electrical signals across and along cellular membranes. Applying the same principles to man-made systems requires the development of synthetic ion channels that can alter their conductance in response to a variety of external manipulations....
journal article 2019
document
Bakhshaee Babaroud, N. (author), Kluba, M.M. (author), Dekker, R. (author), Serdijn, W.A. (author), Giagka, V. (author)
Active implantable medical devices have been developed for diagnosis, monitoring and treatment of large variety of neural disorders. Since the mechanical properties of these devices need to be matched to the tissue, soft materials, such as polymers are often preferred as a substrate [1]. Parylene is a good candidate, as it is highly...
abstract 2019
document
Cudejko, Tomasz (author), van der Esch, Martin (author), van den Noort, Josien C. (author), Rijnhart, Judith J.M. (author), van der Leeden, Marike (author), Roorda, Leo D. (author), Lems, Willem (author), Waddington, Gordon (author), Harlaar, J. (author), Dekker, Joost (author)
Objective: To evaluate whether improvement of proprioception, pain, or dynamic knee instability mediates the effect of wearing a soft knee brace on activity limitations in patients with knee osteoarthritis (OA). Methods: We conducted an analysis of data for 44 patients with knee OA who were enrolled in a laboratory-based trial evaluating the...
journal article 2019
document
Mouter, N. (author), Cabral, Manuel Ojeda (author), Dekker, T. (author), van Cranenburgh, Sander (author)
Environmental effects of transport projects have a weak position in Cost-Benefit Analysis (CBA) which might be rooted in the valuation approach adopted in the dominant style of CBA. This conventional valuation approach has been criticized for not valuing positive and negative impacts of transport projects in relation to each other and for not...
journal article 2019
document
Hol, F.J.H. (author), Whitesides, George M. (author), Dekker, C. (author)
Habitat spatial structure has a profound influence on bacterial life, yet there currently are no low-cost equipment-free laboratory techniques to reproduce the intricate structure of natural bacterial habitats. Here, we demonstrate the use of paper scaffolds to create landscapes spatially structured at the scales relevant to bacterial ecology...
journal article 2019
document
Schrijvers, Jim (author), van den Noort, Josien C. (author), van der Esch, Martin (author), Dekker, Joost (author), Harlaar, J. (author)
Background: Instability of the knee joint during gait is frequently reported by patients with knee osteoarthritis or an anterior cruciate ligament rupture. The assessment of instability in clinical practice and clinical research studies mainly relies on self-reporting. Alternatively, parameters measured with gait analysis have been explored...
review 2019
document
Dekker, R. (author), van der Meer, F.P. (author), Maljaars, J. (author), Sluijs, L.J. (author)
Structures are subjected to cyclic loads that can vary in direction and magnitude, causing constant amplitude mode I simulations to be too simplistic. This study presents a new approach for fatigue crack propagation in ductile materials that can capture mixed-mode loading and overloading. The extended finite element method is used to deal with...
journal article 2019
document
Kawasaki, S. (author), Giagka, V. (author), de Haas, M (author), Louwerse, M. (author), Henneken, V (author), van Heesch, C. (author), Dekker, R. (author)
Vagus nerve stimulators currently on the market can treat epilepsy and depression. Recent clinical trials show the potential for vagus nerve stimulation (VNS) to treat epilepsy, autoimmune disease, and traumatic brain injury. As we explore the benefits of VNS, it is expected that more possibilities for a new treatment will emerge in the future....
conference paper 2019
document
Ha, S. (author), Tang, Y. (author), van Oene, M.M. (author), Janissen, R. (author), Dries, R.M. (author), Solano Hermosilla, B.P. (author), Adam, A.J.L. (author), Dekker, N.H. (author)
Optical trapping of (sub)micron-sized particles is broadly employed in nanoscience and engineering. The materials commonly employed for these particles, however, have physical properties that limit the transfer of linear or angular momentum (or both). This reduces the magnitude of forces and torques, and the spatiotemporal resolution,...
journal article 2019
document
Deshpande, S.R. (author), Brandenburg, Frank (author), Lau, A.W.H.R. (author), Last, M.G.F. (author), Spoelstra, W.M. (author), Reese, L. (author), Wunnava, Sreekar (author), Dogterom, A.M. (author), Dekker, C. (author)
Liquid-liquid phase separation (LLPS), especially coacervation, plays a crucial role in cell biology, as it forms numerous membraneless organelles in cells. Coacervates play an indispensable role in regulating intracellular biochemistry, and their dysfunction is associated with several diseases. Understanding of the LLPS dynamics would...
journal article 2019
document
Nelck, Anne-Marie (author), Sosef, Dirk (author), Zeeman, Dorine (author), Walvisch, Mick (author), Elsenaar, Erik Jan (author), Rodenburg, Paul (author), Lammers, Gerdwin (author), van Schaijk, Pieter (author), Quak, Hans (author), Havelaar, Rogier (author), van den Bosch, Jaap (author), Brinkhof, Rogier (author), Jongeneel, Joeri (author), van Duin, Ron (author), Dekker, Johan (author), Donkersloot, Vincent (author), Spoelstra, Jop (author), Boverhof, Willem (author), Sijtsma, Micha (author), van Hofwegen, Tom (author), Nieuwkerk, Michiel (author), van Gompel, Luc (author)
1. Een Urban Consolidation Centre (UCC) maakt het mogelijk om de stad zero-emissie te beleveren en zorgt ervoor dat goederen gebundeld de stad in gaan. Met als doel het minder belasten van klimaat, gezondheid van mensen en leefbaarheid van de stad. 2. Het UCC is een multimodaal overslagpunt, geschikt voor een variƫteit aan voertuigen....
book chapter 2019
document
Schaich, M. (author), Cama, J. (author), Al Nahas, K. (author), Sobota, Diana (author), Sleath, Hannah (author), Jahnke, Kevin (author), Deshpande, S.R. (author), Dekker, C. (author), Keyser, Ulrich F. (author)
The low membrane permeability of candidate drug molecules is a major challenge in drug development, and insufficient permeability is one reason for the failure of antibiotic treatment against bacteria. Quantifying drug transport across specific pathways in living systems is challenging because one typically lacks knowledge of the exact...
journal article 2019
document
Al Nahas, K. (author), Cama, J. (author), Schaich, M. (author), Hammond, K. (author), Deshpande, S.R. (author), Dekker, C. (author), Ryadnov, M. G. (author), Keyser, UF (author)
The spread of bacterial resistance against conventional antibiotics generates a great need for the discovery of novel antimicrobials. Polypeptide antibiotics constitute a promising class of antimicrobial agents that favour attack on bacterial membranes. However, efficient measurement platforms for evaluating their mechanisms of action in a...
journal article 2019
Searched for:
(1 - 20 of 389)

Pages