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Odijk, T. (author)A theory is presented of the elongation of double-stranded DNA confined in a nanochannel based on a study of the formation of hairpins. A hairpin becomes constrained as it approaches the wall of a channel which leads to an entropic force causing the hairpin to tighten. The DNA in the hairpin remains double-stranded. The free energy of the...journal article 2006
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Brinkers, S. (author), Dietrich, H.R.C. (author), De Groote, F.H. (author), Young, I.T. (author), Rieger, B. (author)The wormlike chain model describes the micromechanics of semiflexible polymers by introducing the persistence length. We propose a method of measuring the persistence length of DNA in a controllable near-native environment. Using a dark field microscope, the projected positions of a gold nanoparticle undergoing constrained Brownian motion are...journal article 2009
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Yuan, C.A. (author), Zhang, G.Q. (author), Han, C.N. (author), Chiang, K.N. (author), Cui, Y. (author)The mechanical characteristics of the long-chain double-stranded DNA (dsDNA) molecule under the axial stretching and lateral unzipping are studied by the clustered atomistic-continuum method (CACM). The CACM consisted of the clustered atom method (CAM) and the atomistic-continuum method (ACM). The CAM treats the specific atomic group as the...journal article 2007