Classifying Candida species using Mixed Integer Optimization based optimal classification trees

Global medical use of azole antifungals and echinocandins has led to an enormous increase in resistant <i>Candida</i> species, that are most commonly associated with fungal infections. A possible mechanism causing resistance are single or simultaneous point mutations in the genes responsible for encoding antifungal target enzymes. The aim of...

Automatic Selection of an Optimal Power Plant Configuration: Using Client Preferences and time based Operational Profiles

Vessels are becoming more and more optimized towards their mission and an increasing amount of systems are considered during this optimization. Most of these considerations occur at an early design stage, where data is scarce and their impact is large. <br/>This research aims to aid designers in considering this growing forest of possible system...