Association between the macrocirculation and the mitochondrial oxygenation in critically ill patients with sepsis

IntroductionThe Cellular Oxygen METabolism (COMET) monitor measures mitochondrial oxygentension (mitoPO2) in vivo at the bedside with delayed fluorescence ofmitochondrial protoporphyrin (PpIX). Blocking microcirculatory oxygen supply bypressing the measurement probe on the skin allows the measurement of mitochondrialoxygen...

Predicting sepsis on the Neonatal Intensive Care Unit

To reduce the mortality rate of sepsis, treatment needs to be started as soon as possible. One should however first be sure about the occurrence of sepsis. Currently, the suspicion of sepsis in premature infants is based on non-specific physiological changes. The detection of alterations in the inter-heartbeat interval preceding sepsis can offer...