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Schaart, D.R. (author), Seifert, S. (author), Vinke, R. (author), Van Dam, H.T. (author), Dendooven, P. (author), Löhner, H. (author), Beekman, F.J. (author)
The use of time-of-flight (TOF) information in positron emission tomography (PET) enables significant improvement in image noise properties and, therefore, lesion detection. Silicon photomultipliers (SiPMs) are solid-state photosensors that have several advantages over photomultiplier tubes (PMTs). SiPMs are small, essentially transparent to 511...
journal article 2010
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Vinke, Elisabeth J. (author), de Groot, Marius (author), Venkatraghavan, Vikram (author), Klein, S. (author), Niessen, W.J. (author), Ikram, M. Arfan (author), Vernooij, Meike W. (author)
With aging, the brain undergoes several structural changes. These changes reflect the normal aging process and are therefore not necessarily pathologic. In fact, better understanding of these normal changes is an important cornerstone to also disentangle pathologic changes. Several studies have investigated normal brain aging, both cross...
journal article 2018
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Seifert, S. (author), Van Dam, H.T. (author), Huizenga, J. (author), Vinke, R. (author), Dendooven, P. (author), Löhner, H. (author), Schaart, D.R. (author)
In a silicon photomultiplier (SiPM), also referred to as multi-pixel photon counter (MPPC), many Geiger-mode avalanche photodiodes (GM-APDs) are connected in parallel so as to combine the photon counting capabilities of each of these so-called microcells into a proportional light sensor. The discharge of a single microcell is relatively well...
journal article 2009
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Van Dam, H.T. (author), Seifert, S. (author), Vinke, R. (author), Dendooven, P. (author), Löhner, H. (author), Beekman, F.J. (author), Schaart, D.R. (author)
The response of a silicon photomultiplier (SiPM) to optical signals is inherently nonproportional due to saturation, afterpulsing, and crosstalk. Existing models of the SiPM response do not account for all of these effects, and therefore, these models are not sufficiently accurate for many applications. In this work, a comprehensive model of the...
journal article 2010
document
Schaart, D.R. (author), Van Dam, H.T. (author), Seifert, S. (author), Vinke, R. (author), Dendooven, P. (author), Löhner, H. (author), Beekman, F.J. (author)
Silicon photomultipliers (SiPMs) are of great interest to positron emission tomography (PET), as they enable new detector geometries, for e.g., depth-of-interaction (DOI) determination, are MR compatible, and offer faster response and higher gain than other solid-state photosensors such as avalanche photodiodes. Here we present a novel detector...
journal article 2009
document
Vinke, Elisabeth J. (author), Huizinga, W. (author), Bergtholdt, Martin (author), Adams, Hieab H. (author), Steketee, Rebecca M.E. (author), Papma, Janne M. (author), De Jong, Frank Jan (author), Niessen, W.J. (author), Ikram, M. Arfan (author)
Brain imaging data are increasingly made publicly accessible, and volumetric imaging measures derived from population-based cohorts may serve as normative data for individual patient diagnostic assessment. Yet, these normative cohorts are usually not a perfect reflection of a patient's base population, nor are imaging parameters such as field...
journal article 2019
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Hiemstra, K.S. (author), van Vuren, S. (author), Vinke, Frederik R.S. (author), Jorissen, Richard E. (author), Kok, M. (author)
Worldwide, rivers provide important socio-economic and environmental functions and are essential to human well-being. The growing demand of user-functions and the change in river conditions due to large-scale morphology and climate change, increase the pressure on lowland river systems (e.g. Rhine, Meuse, Danube and Mississippi). To ensure a...
journal article 2020
document
van Dorsser, Cornelis (author), Vinke, Frederik R.S. (author), Hekkenberg, R.G. (author), van Koningsveld, M. (author)
Prolonged periods of drought affect river discharges and cause water levels and available water depth to drop for extended periods of time. Low water depth has a major impact on the loading capacity of inland ships, and as a consequence on the transport capacity of the overall waterborne supply chain. Individual ship owners have detailed...
journal article 2020
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