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de Jong, T.L. (author)
Liver carcinoma is in the top five leading causes of cancer death worldwide. Patients often require radiologic interventions in which needles are inserted, for example when taking biopsies, accessing blood vessels or bile ducts, and ablating tumors. Accurate and precise needle placement in interventional radiology is important, but also...
doctoral thesis 2019
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Kittelmann, J. (author)
The downstream process development for biopharmaceuticals is faced with increasing challenges. A growing market of drug candidates and new molecule families, as well as a rising trend to personalized medicine lead to an increase in market diversity. At the same time more purification techniques and materials become available, resulting in an...
doctoral thesis 2019
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Houtgast, E.J. (author)
Developments in sequencing technology have drastically reduced the cost of DNA sequencing. The raw sequencing data being generated requires processing through computationally demanding suites of bioinformatics algorithms called genomics pipelines. The greatly decreased cost of sequencing has resulted in its widespread adoption, and the amount of...
doctoral thesis 2019
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Jovanovic, Nenad (author)
The growing penetration of renewable energy sources in electricity systems requires adapting operation models to face the inherent variability and uncertainty of wind or solar generation. In addition, the volatility of fuel prices (such as natural gas) or the uncertainty of the hydraulic natural inflows requires to take into account all these...
doctoral thesis 2019
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Liu, Q. (author)
Spreading phenomena such as spreading of diseases, information and computer viruses are ubiquitous in nature and man-made systems, but the understanding of them is still insufficient. This dissertation focuses on the analysis of a basic mathematical model of spreading phenomena running on underlying network structures and aims to complete the...
doctoral thesis 2019
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Aben, N.N. (author)
In order to improve anti-cancer treatment, we need to better understand why some patients respond to a given anti-cancer treatment, while others do not. To this end, several large-scale drug response screens have been performed in recent years, in which hundreds of tumor cell lines have been characterized formany molecular features (e.g....
doctoral thesis 2019
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Lu, T. (author)
Rotating ring-like structures are very commonly used in civil, mechanical and aerospace engineering. Typical examples of such structures are components in turbomachinery, compliant gears, rolling tyres and flexible train wheels. At the micro-scale, rotating ring models find their applications in the field of ring gyroscopes, in which high...
doctoral thesis 2019
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van Rossum, S.A.P. (author)
Nature is capable of constantly adapting some of its assembled structures in response to external and internal signals. For instance, microtubuli grow and shrink upon cell division and cellular transport. Furthermore, actin fibers play a major role in muscle contraction and cell signaling. To achieve these transient functions, such assembled...
doctoral thesis 2019
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Zhang, F. (author)
Materials are omnipresent. Recognizing materials helps us with inferring their physical and chemical properties, for instance if they are compressible, slippery, sweet and juicy. Yet in literature, much less attention has been paid to material perception than to object perception. This dissertation presents studies on a method to systematically...
doctoral thesis 2019
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Mahajan, V.V. (author)
Gas-solid fluidized beds are widely used in various industries due to their favourable mixing, and mass and heat transfer characteristics. Fluid catalytic cracking, polymerization, drying, and granulation are a few examples of their applications. In recent years, there has been increased application of fluidized beds in biomass gasification and...
doctoral thesis 2019
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Barciela Rial, M. (author)
Fine cohesive sediment is starting to be used for nature building projects because traditionally used sandy sediment is becoming scarce. The Marker Wadden is one of the first projects using natural fine cohesive sediment for this purpose. TheMarkerWadden aims to improve the ecosystem of LakeMarkermeer (The Netherlands) by constructing a wetland...
doctoral thesis 2019
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Zhang, H. (author)
Cementitious materials are heterogeneous on mutliple length scales, from nanometres to metres. Consequently, their macroscopic mechanical properties are affected by material structures at all length scales. In pursuit of fundamental understanding the relationship between their multiscale heterogeneous material structure and mechanical properties...
doctoral thesis 2019
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Konijnenberg, A.P. (author)
In this thesis, several phase retrieval methods are discussed. Since the focus will mainly be on theory rather than experiment, the structure has been determined by the similarities and differences of the mathematics of these methods. For example, a distinction is made between non-iterative and iterative methods, and between single-shot...
doctoral thesis 2019
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Ochôa, Pedro (author)
The adoption of composites as aircraft primary structural material has created a real need for a new aircraft maintenance philosophy to enable almost real-time structural condition assessment. It is thus crucial to develop structural health monitoring (SHM) systems capable of performing damage diagnostic and remaining useful life prognostic. At...
doctoral thesis 2019
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Velichko, E. (author)
Humanity needs to increase use of renewable sources of materials and energy. Biomass can be used for both of these needs. Cellulose is the main component of biomass. Understanding the multi-level hierarchical structure of cellulose holds the key tomultiple applications of this material. One of the promising applications of lignocellulsic biomass...
doctoral thesis 2019
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Sharma, S. (author)
Seismic waves from active experiments carry information regarding the subsurface in the form of reflected data that is recorded at the surface. This recorded data is subjected to sophisticated processing methods to estimate relevant parameters describing the geology of the subsurface. Traditionally the recorded data is used to create an image of...
doctoral thesis 2019
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Roubos, A.A. (author)
In the coming years, thousands of quay walls will approach the end of their intended fifty-year design lifetime and become part of lifetime extension programmes throughout the world. It is presently unclear how reliable these structures are and whether they are still capable of bearing ship and crane loads. An appropriate assessment of a quay...
doctoral thesis 2019
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Ravi, A.M. (author)
The formation of bainite in steels is one of the most intensely researched topics in the field of metallurgy. Despite the importance of bainite among the modern-day steels, even a qualitative theory to explain the bainite formation still remains a subject of controversy due to the complexity of its formation mechanism. Currently, two competing...
doctoral thesis 2019
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Steller, F.P. (author)
doctoral thesis 2019
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Guatame-Garcia, L.A. (author)
Industrial minerals are essential to human activity. The products derived from them make an integral part of a wide range of materials that are ubiquitously present in our daily lives. The performance and attributes of these materials depend significantly on the properties and quality of the industrial minerals and the products generated from...
doctoral thesis 2019
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