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document
van den Berg, B.A. (author), Reinders, M.J.T. (author), Bellomo, Domenico (author)
poster 2009
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Hulsman, M. (author), Unadkat, HV (author), Cornelissen, Kamiel (author), de Boer, Jan (author), Reinders, M.J.T. (author)
poster 2011
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Taskesen, E. (author), Havermans, M (author), Van Lom, K (author), Sanders, Mathijs (author), van Norden, Yvette (author), Bindels, Eric (author), Hoogenboezem, Remco (author), Reinders, M.J.T. (author), Valk, P.J.M. (author), More Authors (author)
Acute Myeloid Leukemia is a highly diverse disease containing many cytogenetic and molecular abnormalities. We analyzed the DNA methylation<br/>(DMP) and gene expression profiles (GEP) of 344 AML patients using an unsupervised and supervised approach. We hypothesized to better<br/>characterize the disease phenotype by combing these features as...
poster 2011
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van den Berg, B.A. (author), Reinders, M.J.T. (author), Pel, HJ (author), Wu, L (author), Roubos, J.A. (author), de Ridder, D. (author)
Aspergillus niger is widely used for industrial enzyme production. Knowledge on high-level protein secretion could be useful to improve production rates. We used sequencebased classification methods to identify important properties<br/>for successful high-level secretion, which will be used to redesign proteins for improved secretion.
poster 2011
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Babaei, S. (author), Hulsman, M. (author), Reinders, M.J.T. (author), de Ridder, J. (author)
We introduce a multi-scale kernel diffusion framework and apply it to a large collection of murine retroviral insertional mutagenesis data. The diffusion strength plays the role of scale parameter. As a result, in addition to detecting genes with frequent mutations in their genomic vicinity (red nodes in the interaction graph) we can also find...
poster 2012
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van den Berg, B.A. (author), Reinders, M.J.T. (author), Pel, HJ (author), Roubos, J.A. (author), de Ridder, D. (author)
poster 2012
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Mahfouz, A.M.E.T.A. (author), Ziats, Mark N. (author), Rennert, Owen M. (author), Lelieveldt, B.P.F. (author), Reinders, M.J.T. (author)
We analyzed the spatial-temporal co-expression relationships of 455 genes previously implicated in Autism spectrum disorder (ASD) using the BrainSpan transcriptome atlas. Understanding how the heterogenous set of ASD-related genes contribute to normal brain development helps identifying cellular/molecular processes which are commonly disrupted...
poster 2013
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van den Berg, B.A. (author), Thornton, JM (author), Reinders, M.J.T. (author), de Ridder, D. (author), Beer, TAP (author)
Our aim is to prioritize human missense mutations by their probability of being disease causing. Such a computational method could be used to obtain a reduced set of mutations with a relatively large fraction of disease related mutations, thereby aiding in the search for this type of mutation within a large mutation set.<br/><br/>Whereas a range...
poster 2013
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Gehrmann, T. (author), Pelkmans, Jordi F. (author), Lugones, Luis G. (author), Wösten, Han A.B. (author), Reinders, M.J.T. (author)
poster 2013
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Duong, M.T. (author), Ranasinghe, R.W.M.R.J.B. (author), Luijendijk, A.P. (author), Walstra, D.J.R. (author), Roelvink, J.A. (author)
Tidal inlets are of great societal importance and are also the most morphologically dynamic regions in the coastal zone. Therefore, they are of great scientific interest. Their behaviour is governed by the delicate balance of oceanic processes such as tides, waves and mean sea level (MSL), and fluvial/estuarine processes such as riverflow. All...
poster 2014
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Palmen, LJ (author), Schetters, M.J.A. (author), van der Hoek, J.P. (author), Kramer, O.J.I. (author), Kors, L.J. (author), Hofs, B (author), Koppers, H (author)
In The Netherlands, 50% of the drinking water is treated with pellet softening for various reasons: i) public health (heavy metal solubility), ii) costs (warm water device maintenance, energy and soap requirement), iii) environmental benefits (energy and soap requirement) and iv) customer comfort (scaling) [2]. Calcium carbonate crystallizes on...
poster 2014
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Willems, C.J.L. (author)
Currently six geothermal doublets are realized in the WNB. Five of these doublets target the same Lower Cretaceous fluvial sandstone interval, the Nieuwerkerk Formation. About 40 exploration licences are granted. Many of them also have sandstones in the same fluvial interval, the Nieuwerkerk Formation as a target. To successfully and efficiently...
poster 2014
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Bordogna, G. (author), van der Kolk, N.J. (author), Huijsmans, R.H.M. (author), Keuning, J.A. (author), Fossati, F.V. (author)
Development of a Performance Prediction Program for Commercial Ships
poster 2015
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Mahfouz, A.M.E.T.A. (author), Lelieveldt, B.P.F. (author), Grefhorst, Aldo (author), Mol, Isabel M. (author), Sips, Hetty C.M. (author), van den Heuvel, José K. (author), Visser, Jenny A. (author), Reinders, M.J.T. (author), Meijer, Onno C. (author), More Authors (author)
Steroid hormones coordinate the activity of many brain regions by binding to nuclear receptors that act as transcription factors. This study uses genome-wide correlation of gene expression in the mouse brain to discover (i) brain regions that respond in a similar manner to particular steroids, (ii) signaling pathways that are used in a steroid...
poster 2015
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van Toorenenburg, K.A. (author), Donselaar, Rick (author), Flores Colmenares, J.S. (author), Groenenberg, RM (author), Pluymaekers, MP (author), Vandeweijer, VP (author), van de Weerd, AA (author)
poster 2015
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Yuan, K. (author), Knoop, V.L. (author), Hoogendoorn, S.P. (author)
It has been empirically observed for years that the queue<br/>discharge rate is lower than the pre-queue capacity. This is<br/>called the capacity drop. The magnitude of capacity drop varies over a wide range depending on the local traffic conditions. However, up to now it is unknown what determines the capacity drop value. In fact, there is...
poster 2015
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Prieto Hoces, A.I. (author)
poster 2015
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Chandra Mouli, G.R. (author), Huijbrechts, Paul (author)
poster 2015
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Bijster, R.J.F. (author), Sadeghian Marnani, H. (author), van Keulen, A. (author)
poster 2016
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Mohammadi, M. (author), Hofman, Wout (author), Tan, Y. (author)
This paper proposes statistical approaches to test if the difference between two ontology matchers is real. Specifically, the performances of the matchers over multiple data sets are obtained and based on their performances, the conclusion can be drawn whether one method is better than one another or not. To do so, the paired t-test and...
poster 2016
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