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Martens, Koen (author), van Beljouw, Sam P.B. (author), van der Els, Simon (author), Vink, J.N.A. (author), Baas, Sander (author), Vogelaar, George A. (author), Brouns, S.J.J. (author), van Baarlen, Peter (author), Kleerebezem, Michiel (author), Hohlbein, Johannes (author)
CRISPR-Cas9 is widely used in genomic editing, but the kinetics of target search and its relation to the cellular concentration of Cas9 have remained elusive. Effective target search requires constant screening of the protospacer adjacent motif (PAM) and a 30 ms upper limit for screening was recently found. To further quantify the rapid...
journal article 2019
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Hiemstra-van Mastrigt, S. (author), Ottens, Richard (author), Vink, P. (author)
Interferences during the boarding procedure are one of the main reasons of delay and increased turnaround time, becoming a relevant problem for airlines. Observations of the boarding process and questionnaires inside the aircraft revealed three main bottlenecks during the boarding process: (1) Hand luggage: Storage space is not sufficient and...
journal article 2019
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Vendel, M.E. (author), Dangal, Sagar (author), Coppens, J. (author), Hiemstra-van Mastrigt, S. (author), Vink, P. (author)
Airplane boarding is a time-consuming procedure due to a number of factors. First of all, passengers cannot pass each other in the aisles, but also stress is experienced in finding the seat or the space to store hand luggage and some passengers repack their luggage in the aisle. To reduce boarding time and improve the overall boarding experience...
journal article 2019
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Piro, S. (author), Fiorillo, I. (author), Anjani, S. (author), Smulders, M. (author), Naddeo, A. (author), Vink, P. (author)
This research aims to study the effect of seat and/or backrest rotation on comfort and quality of conversation. Different sitting arrangements were tested to study the effect of the seat layout on: 1) (dis)comfort experience; 2) conversation quality and 3) postures. Two seats were arranged in different angles (0° 45° 90° and 180°) at the same...
journal article 2019
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Torkashvand, Golnoosh (author), Stephane, Lucas (author), Vink, P. (author)
Among airlines and aircraft manufacturers there is much attention for passenger experience. However, there is not much literature on how the activities of passengers can be supported by the aircraft interior. The current study focuses on the need finding and requirements analysis of flight passengers. Twenty-three activities were defined...
journal article 2019
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Coppens, Jessica (author), Dangal, Sagar (author), Vendel, M.E. (author), Anjani, S. (author), Akkerman, Stefan (author), Hiemstra-van Mastrigt, S. (author), Vink, P. (author)
The airplane (de)boarding process is not organized optimally. The goal of this paper is to search for improvement possibilities. In this paper literature is reviewed, boarding characteristics are studied in a field study and a pilot study with a new way of hand luggage stowing is performed. Computer simulations indicate that there are more...
journal article 2018
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de Korte, E.M. (author), Wiezer, Noortje (author), Bakhuys Roozeboom, Maartje (author), Vink, P. (author), Kraaij, Wessel (author)
Background: Employees remain at risk of developing physical and mental health problems. To improve the lifestyle, health, and productivity many workplace interventions have been developed. However, not all of these interventions are effective. Mobile and wireless technology to support health behavior change (mobile health [mHealth] apps) is a...
journal article 2018
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de Korte, E.M. (author), Wiezer, Noortje (author), Janssen, Joris (author), Vink, P. (author), Kraaij, Wessel (author)
Background: To improve workers’ health and well-being, workplace interventions have been developed, but utilization and reach are unsatisfactory, and effects are small. In recent years, new approaches such as mobile health (mHealth) apps are being developed, but the evidence base is poor. Research is needed to examine its potential and to assess...
journal article 2018
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Bouwens, J.M.A. (author), Hiemstra-van Mastrigt, S. (author), Vink, P. (author)
Bubb, Bengler, Grünen, and Vollrath (2015) identified six environmental comfort factors and ordered them from most important to least important (smell, light, vibrations, sound, climate and anthropometry). This paper attempts to verify whether this suggested order of comfort-related factors also applies to the expectations of aircraft passengers...
journal article 2018
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Kieper, S.N. (author), Almendros Romero, C. (author), Behler, Juliane (author), McKenzie, R.E. (author), Luzia De Nóbrega, F. (author), van Eijkeren-Haagsma, A.C. (author), Vink, J.N.A. (author), Hess, Wolfgang R. (author), Brouns, S.J.J. (author)
CRISPR-Cas systems adapt their immunological memory against their invaders by integrating short DNA fragments into clustered regularly interspaced short palindromic repeat (CRISPR) loci. While Cas1 and Cas2 make up the core machinery of the CRISPR integration process, various class I and II CRISPR-Cas systems encode Cas4 proteins for which...
journal article 2018
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Van De Meerendonk, Suzanne (author), van Eikema Hommes, M.H. (author), Vink, Ester (author), Van Drunen, Ad (author)
This case study explores the original significance and contexts of a series of political allegories painted by Theodoor van Thulden (1606-1669) for the 's-Hertogenbosch (Bois-le-Duc) Town Hall. In considering their commission history, current attributions, their relevant historical and political contexts and their initial placement in the...
journal article 2017
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Navarro, R. (author), Agócs, Tibor (author), Venema, L (author), van Amerongen, A.H. (author), Rodenhuis, M. (author), Hoogeveen, Ruud W. M. (author), Coppens, T (author), Brandl, B.R. (author), Vink, R. (author)
<br/>Immersed gratings offer several advantages over conventional gratings: more compact spectrograph designs, and by using standard semiconductor industry techniques, higher diffraction-efficiency and lower stray-light can be achieved. We present the optical tests of the silicon immersed grating demonstrator for the Mid-infrared E-ELT Imager...
conference paper 2017
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Molenbroek, J.F.M. (author), Albin, Thomas J (author), Vink, P. (author)
This paper reports the results of an investigation into changes in body shape anthropometry over the past several decades and discusses the impact of those changes on seating in transport, especially airliners. Changes in some body shape dimensions were confirmed in a sample of students at TU Delft; several of the changes, e.g. hip breadth,...
journal article 2017
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van Veen, S.A.T. (author), Orlinskiy, V. (author), Franz, M. (author), Vink, P. (author)
Static sitting when travelling by car is known to cause physical fatigue. It is generally encouraged to periodically engage in non-sedentary activities, but this is not possible when traveling by car. The present study aims to investigate the influence of moving the vehicle occupant’s body passively. This posture variation is realized by...
journal article 2015
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Bazley, C. (author), Nugent, R. (author), Vink, P. (author)
A review of literature on comfort and discomfort indicates an increase in physical discomfort during the workday. In this paper, three different types of occupations were studied to identify whether a similar discomfort pattern exists in these occupations while participants perform work throughout the work day and workweek. Results are that...
journal article 2015
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Bakker, I.C. (author), van der Voordt, Theo (author), Vink, P. (author), de Boon, J (author), Bazley, C (author)
Studies on color preferences are dependent on the topic and the relationships with personal characteristics, particularly personality, but these are seldom studied in one population. Therefore a questionnaire was collected from 1095 Dutch people asking for color preferences about different topics and relating them to personal characteristics.<br...
journal article 2015
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Van Veen, S.A.T. (author), Van Mastrigt, S. (author), Kamp, I. (author), Vink, P. (author)
BACKGROUND: There is a demand for interiors to support other activities in a car than controlling the vehicle. Currently, this is the case for the car passengers and – in the future – autonomous driving cars will also facilitate drivers to perform other activities. One of these activities is working with handheld devices. OBJECTIVE: Previous...
journal article 2014
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Vink, P. (author)
public lecture 2014
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Bakker, I.C. (author), van der Voordt, Theo (author), de Boon, J (author), Vink, P. (author)
This paper presents a discursive review of the dimensions pleasure, arousal and dominance that Mehrabian and Russell developed in 1974 to assess environmental perception, experience, and psychological responses. Since then numerous researchers applied these dimensions to assess the experience of the physical environment and its perceived...
journal article 2014
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Bakker, I.C. (author), van der Voordt, Theo (author), Vink, P. (author), de Boon, J (author)
This research discusses the validity of applying questionnaires in colour research in real life settings.<br/>In the literature the conclusions concerning the influences of colours on human performance and well-being are often conflicting. This can be caused by the artificial setting of the test process. Applying questionnaires could also be a...
journal article 2014
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