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Luan, Ying (author), Renaud, Guillaume (author), Raymond, Jason L. (author), Segers, Tim (author), Lajoinie, Guillaume (author), Beurskens, Robert (author), Mastik, Frits (author), Kokhuis, Tom J A (author), van der Steen, A.F.W. (author), Versluis, Michel (author), de Jong, N. (author)
In this study we present a combined optical sizing and acoustical characterization technique for the study of the dynamics of single freely-floating ultrasound contrast agent microbubbles exposed to long burst ultrasound excitations up to the milliseconds range. A co-axial flow device was used to position individual microbubbles on a...
journal article 2016
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Lajoinie, Guillaume (author), Lee, Jeong Yu (author), Owen, Joshua (author), Kruizinga, P. (author), de Jong, N. (author), Van Soest, Gijs (author), Stride, Eleanor (author), Versluis, Michel (author)
Photoacoustic (PA) imaging offers several attractive features as a biomedical imaging modality, including excellent spatial resolution and functional information such as tissue oxygenation. A key limitation, however, is the contrast to noise ratio that can be obtained from tissue depths greater than 1-2 mm. Microbubbles coated with an...
journal article 2017
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Lajoinie, Guillaume (author), Linnartz, Erik (author), Kruizinga, P. (author), de Jong, N. (author), Stride, Eleanor (author), Van Soest, Gijs (author), Versluis, Michel (author)
Microbubbles are used to enhance the contrast in ultrasound imaging. When coated with an optically absorbing material, these bubbles can also provide contrast in photoacoustic imaging. This multimodal aspect is of pronounced interest to the field of medical imaging. The aim of this paper is to provide a theoretical framework to describe the...
journal article 2017
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Lajoinie, Guillaume (author), Luan, Ying (author), Gelderblom, Erik (author), Dollet, Benjamin (author), Mastik, Frits (author), Dewitte, Heleen (author), Lentacker, Ine (author), de Jong, N. (author), Versluis, Michel (author)
journal article 2018
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Spiekhout, Sander (author), Voorneveld, J.D. (author), Van Elburg, Benjamin (author), Renaud, G.G.J. (author), Segers, Tim (author), Lajoinie, Guillaume P.R. (author), Versluis, Michel (author), Verweij, M.D. (author), de Jong, N. (author), Bosch, Johannes G. (author)
Ultrasound (US) contrast agents consist of microbubbles ranging from 1 to 10 μm in size. The acoustical response of individual microbubbles can be studied with high-frame-rate optics or an "acoustical camera"(AC). The AC measures the relative microbubble oscillation while the optical camera measures the absolute oscillation. In this article,...
journal article 2022
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