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Kolken, H.M.A. (author), Lietaert, K. (author), van der Sloten, T. (author), Pouran, B. (author), Meynen, A. (author), Van Loock, G. (author), Weinans, Harrie (author), Scheys, L. (author), Zadpoor, A.A. (author)The innovative design of orthopedic implants could play an important role in the development of life-lasting implants, by improving both primary and secondary implant fixations. The concept of meta-biomaterials aims to achieve a unique combination of mechanical, mass transport, and biological properties through optimized topological design of...journal article 2020
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van Hengel, I.A.J. (author), Gelderman, F. S.A. (author), Athanasiadis, S. (author), Minneboo, M.B. (author), Weinans, Harrie (author), Fluit, A. C. (author), van der Eerden, B.C.J. (author), Fratila-Apachitei, E.L. (author), Apachitei, I. (author), Zadpoor, A.A. (author)The holy grail of orthopedic implant design is to ward off both aseptic and septic loosening for long enough that the implant outlives the patient. Questing this holy grail is feasible only if orthopedic biomaterials possess a long list of functionalities that enable them to discharge the onerous task of permanently replacing the native bone...journal article 2020
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Li, Y. (author), Jahr, H. (author), Lietaert, K. (author), Pavanram, P. (author), Yilmaz, A. (author), Fockaert, L.I. (author), Leeflang, M.A. (author), Pouran, B. (author), Gonzalez Garcia, Y. (author), Weinans, Harrie (author), Mol, J.M.C. (author), Zhou, J. (author), Zadpoor, A.A. (author)Additively manufactured (AM) topologically ordered porous metallic biomaterials with the proper biodegradation profile offer a unique combination of properties ideal for bone regeneration. These include a fully interconnected porous structure, bone-mimicking mechanical properties, and the possibility of fully regenerating bony defects. Most...journal article 2018
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Ahmadi, S.M. (author), Hedayati, R. (author), Li, Y (author), Lietaert, K. (author), Tümer, N. (author), Fatemi, A. (author), Rans, C.D. (author), Pouran, B. (author), Weinans, Harrie (author), Zadpoor, A.A. (author)Additive manufacturing (AM) techniques enable fabrication of bone-mimicking meta-biomaterials with unprecedented combinations of topological, mechanical, and mass transport properties. The mechanical performance of AM meta-biomaterials is a direct function of their topological design. It is, however, not clear to what extent the material type...journal article 2018
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Li, Y. (author), Zhou, J. (author), Pavanram, P. (author), Leeflang, M.A. (author), Fockaert, L.I. (author), Pouran, B. (author), Tümer, N. (author), Schröder, K. U. (author), Mol, J.M.C. (author), Weinans, Harrie (author), Jahr, H. (author), Zadpoor, A.A. (author)An ideal bone substituting material should be bone-mimicking in terms of mechanical properties, present a precisely controlled and fully interconnected porous structure, and degrade in the human body to allow for full regeneration of large bony defects. However, simultaneously satisfying all these three requirements has so far been highly...journal article 2017