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Ye, Xiaotong (author), Leeflang, M.A. (author), Wu, Chengtie (author), Chang, Jiang (author), Zhou, J. (author), Huan, Z. (author)
Porous Ti-6Al-4V scaffolds fabricated by means of selective laser melting (SLM),<br/>having controllable geometrical features and preferable mechanical properties, have been developed as a class of biomaterials that hold promising potential for bone repair. However, the inherent bio-inertness of the Ti-6Al-4V alloy as the matrix of the scaffolds...
journal article 2017
document
Wang, S (author), Xu, Y (author), Zhou, J. (author), Li, H (author), Chang, Jiang (author), Huan, Z (author)
Iron-matrix composites with calcium silicate (CS) bioceramic as the reinforcing phase were fabricated through powder metallurgy processes. The microstructures, mechanical properties, apatite deposition and biodegradation behavior of the Fe-CS composites, as well as cell attachment and proliferation on<br/>their surfaces, were characterized. In...
journal article 2017
document
Naddaf Dezfuli, S. (author), Huan, Z. (author), Mol, J.M.C. (author), Leeflang, M.A. (author), Chang, Jiang (author), Zhou, J. (author)
The present research was aimed at developing magnesium-matrix composites that could allow effective control over their physiochemical and mechanical responses when in contact with physiological solutions. A biodegradable, bioactive ceramic - bredigite was chosen as the reinforcing phase in the composites, based on the hypothesis that the...
journal article 2017
document
Naddaf Dezfuli, S. (author), Huan, Z. (author), Mol, J.M.C. (author), Leeflang, M.A. (author), Chang, J. (author), Zhou, J. (author)
The human body is a buffered environment where pH is effectively maintained. HEPES is a biological buffer often used to mimic the buffering activity of the body in in vitro studies on the degradation behavior of magnesium. However, the influence of HEPES on the degradation behavior of magnesium in the DMEM pseudo-physiological solution has not...
journal article 2014
document
Huan, Z. (author), Zhou, J. (author), Duszczyk, J. (author)
In this study, bioactive glass (BG, 45S5) particles were added to a biodegradable magnesium alloy(ZK30) through a semi-solid high-pressure casting process in order to improve the surface biocompatibility of the biomaterial and potentially its bioactivity. The observation of the as-cast microstructures of ZK30-BG composites indicated homogeneous...
journal article 2010
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Huan, Z.G. (author), Leeflang, M.A. (author), Zhou, J. (author), Fratila-Apachitei, L.E. (author), Duszczyk, J. (author)
Zinc and zirconium were selected as the alloying elements in biodegradable magnesium alloys, considering their strengthening effect and good biocompatibility. The degradation rate, hydrogen evolution, ion release, surface layer and in vitro cytotoxicity of two Mg–Zn–Zr alloys, i.e. ZK30 and ZK60, and a WE-type alloy (Mg–Y–RE–Zr) were...
journal article 2010
document
Huan, Z. (author), Chang, J. (author), Zhou, J. (author)
A low-temperature fabrication method for highly porous bioactive scaffolds was developed. The two-step method involved the foaming of tricalcium silicate cement paste and hydration to form calcium silicate hydrate and calcium hydroxide. Scaffolds with a combination of interconnected macro- and micro-sized pores were fabricated by making use of...
journal article 2009
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