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Leinders, S.M. (author), Westerveld, W.J. (author), Pozo, J. (author), Neer, P.L.M.J. (author), Snyder, B. (author), O'Brien, P. (author), Urbach, H.P. (author), de Jong, N. (author), Verweij, M.D. (author)With the increasing use of ultrasonography, especially in medical imaging, novel fabrication techniques together with novel sensor designs are needed to meet the requirements for future applications like three-dimensional intercardiac and intravascular imaging. These applications require arrays of many small elements to selectively record the...journal article 2015
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Shabanimotlagh, M. (author), Raghunathan, S.B. (author), Bera, D. (author), Chen, Z. (author), Chen, C. (author), Daeichin, V. (author), Pertijs, M.A.P. (author), Bosch, J.G. (author), de Jong, N. (author), Verweij, M.D. (author)Echocardiography is a portable, safe, and low-cost imaging technique for accurate assessment of the heart. In transesophageal echocardiography (TEE) the esophagus is utilized as the imaging window to examine the cardiac anatomy and function. In conventional TEE probes, a one-dimensional (1D) ultrasound array is employed to obtain two-dimensional...abstract 2017
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Chen, C. (author), Chen, Z. (author), Bera, Deep (author), Raghunathan, S.B. (author), Shabanimotlagh, M. (author), Noothout, E.C. (author), Chang, Z.Y. (author), Ponte, Jacco (author), Prins, Christian (author), Vos, H.J. (author), Bosch, J.G. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)This paper presents a power-and area-efficient front-end application-specific integrated circuit (ASIC) that is directly integrated with an array of 32 × 32 piezoelectric transducer elements to enable next-generation miniature ultrasound probes for real-time 3-D transesophageal echocardiography. The 6.1 × 6.1 mm<sup>2</sup> ASIC, implemented...journal article 2017
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Tan, M. (author), Chen, C. (author), Chen, Z. (author), Janjic, Jovana (author), Daeichin, V. (author), Chang, Z.Y. (author), Noothout, E.C. (author), van Soest, G. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)This paper presents an area- and power-efficient application-specified integrated circuit (ASIC) for 3-D forward-looking intravascular ultrasound imaging. The ASIC is intended to be mounted at the tip of a catheter, and has a circular active area with a diameter of 1.5 mm on the top of which a 2-D array of piezoelectric transducer elements is...journal article 2018
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Kang, E. (author), Ding, Q. (author), Shabanimotlagh, M. (author), Kruizinga, P. (author), Chang, Z.Y. (author), Noothout, E.C. (author), Vos, H.J. (author), Bosch, J.W. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)This paper presents an ultrasound transceiver application-specific integrated circuit (ASIC) designed for 3-D ultrasonic imaging of the carotid artery. This application calls for an array of thousands of ultrasonic transducer elements, far exceeding the number of channels of conventional imaging systems. The 3.6 x 6.8 mm&#x00B2; ASIC...journal article 2018
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Bera, D. (author), Van Den Adel, Franc (author), Radeljic-Jakic, Nikola (author), Lippe, Boris (author), Soozande, M. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author), Kruizinga, P. (author), Daeichin, V. (author), Vos, H.J. (author), van der Steen, A.F.W. (author), Bosch, Johan G. (author), de Jong, N. (author)We describe a 3-D multiline parallel beamforming scheme for real-time volumetric ultrasound imaging using a prototype matrix transesophageal echocardiography probe with diagonally diced elements and separated transmit and receive arrays. The elements in the smaller rectangular transmit array are directly wired to the ultrasound system. The...journal article 2018
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Daeichin, V. (author), Bera, D. (author), Raghunathan, S.B. (author), Shabanimotlagh, M. (author), Chen, Z. (author), Chen, C. (author), Noothout, E.C. (author), Vos, H.J. (author), Pertijs, M.A.P. (author), de Jong, N. (author), Verweij, M.D. (author)This paper presents the design, fabrication and characterization of a miniature PZT-on-CMOS matrix transducer for real-time pediatric 3-dimensional (3D) transesophageal echocardiography (TEE). This 3D TEE probe consists of a 32 × 32 array of PZT elements integrated on top of an Application Specific Integrated Circuit (ASIC). We propose a...journal article 2018
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Janjic, Jovana (author), Tan, M. (author), Daeichin, V. (author), Noothout, E.C. (author), Chen, C. (author), Chen, Z. (author), Chang, Z.Y. (author), Beurskens, Robert H.S.H. (author), van Soest, G. (author), van der Steen, A.F.W. (author), Verweij, M.D. (author), Pertijs, M.A.P. (author), de Jong, N. (author)Intravascular ultrasound is an imaging modality used to visualize atherosclerosis from within the inner lumen of human arteries. Complex lesions like chronic total occlusions require forward-looking intravascular ultrasound (FL-IVUS), instead of the conventional side-looking geometry. Volumetric imaging can be achieved with 2D array...journal article 2018
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Bera, D. (author), Raghunathan, S.B. (author), Chen, C. (author), Chen, Z. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author), Daeichin, V. (author), Vos, H.J. (author), van der Steen, A.F.W. (author), de Jong, N. (author), Bosch, J.G. (author)Until now, no matrix transducer has been realized for 3D transesophageal echocardiography (TEE) in pediatric patients. In 3D TEE with a matrix transducer, the biggest challenges are to connect a large number of elements to a standard ultrasound system, and to achieve a high volume rate (>200 Hz). To address these issues, we have recently...journal article 2018
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Massaad Mouawad, J.M. (author), van Neer, P.L.M.J. (author), van Willigen, D.M. (author), de Jong, N. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author)Typically, ultrasonic flow meters assume linear wave propagation. Nevertheless, if the transducers of an ultrasonic flow sensor excite a pressure wave with a high amplitude, nonlinear wave propagation effects become significant. The appearance of higher harmonics increases the bandwidth of the received signal, which may potentially lead to a...conference paper 2018
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Beekers, D.I. (author), van Rooij, Tom (author), van der Steen, A.F.W. (author), de Jong, N. (author), Verweij, M.D. (author), Kooiman, Klazina (author)Ultrasound contrast agents consist of gas-filled coated microbubbles that oscillate upon ultrasound insonification. Their characteristic oscillatory response provides contrast enhancement for imaging and has the potential to locally enhance drug delivery. Since microbubble response depends on the local acoustic pressure, an ultrasound...journal article 2018
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Chen, C. (author), Chen, Z. (author), Bera, Deep (author), Noothout, E.C. (author), Chang, Z.Y. (author), Tan, M. (author), Vos, H.J. (author), Bosch, Johan G. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)This paper presents a front-end application-specified integrated circuit (ASIC) integrated with a 2-D PZT matrix transducer that enables in-probe digitization with acceptable power dissipation for the next-generation endoscopic and catheter-based 3-D ultrasound imaging systems. To achieve power-efficient massively parallel analog-to-digital...journal article 2018
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Fool, F. (author), de Wit, J. (author), Vos, H.J. (author), Bera, D. (author), de Jong, N. (author), Verweij, M.D. (author)The huge amount of data that needs to be transferred between probe and imaging system becomes a major issue when the data transfer capacity is limited, e.g. in handheld systems, wireless probes and miniaturized probes. The amount of data can be significantly reduced by using two-stage beamforming. The first stage consists of a fixed focus...conference paper 2018
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Sabbadini, A. (author), Caenen, A.F.M. (author), Vos, H.J. (author), de Jong, N. (author), Verweij, M.D. (author)Shear Wave Elastography (SWE) has been proposed to investigate cardiac health by non-invasively monitoring tissue stiffness. Previous work has shown that the plate-like geometry of the Interventricular Septum (IVS) may result in a dispersion similar to Lamb waves, complicating the link between shear wave speed and cardiac stiffness. However, the...journal article 2019
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- Soozande, Mehdi (author), Ossenkoppele, B.W. (author), Hopf, Y.M. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author), Vos, H.J. (author), Bosch, J.G. (author), de Jong, N. (author) poster 2019
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Ossenkoppele, B.W. (author), Daeichin, V. (author), Rodriguez Hernandez, K.E. (author), de Jong, N. (author), Verweij, M.D. (author), Schouten, A.C. (author), Mugge, W. (author)Effective treatment of movement disorders requires thorough understanding of human limb control. Joint dynamics can be assessed using robotic manipulators and system identification. Due to tendon compliance, joint angle and muscle length are not proportional. This study uses plane-wave ultrasound imaging to investigate the dynamic relation...conference paper 2019
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Waasdorp, R. (author), Mugge, W. (author), Vos, H.J. (author), de Groot, J.H. (author), de Jong, N. (author), Verweij, M.D. (author), Schouten, A.C. (author), Daeichin, V. (author)Current methods to track the progression and evaluate treatment of muscular dystrophies are scarce. The electromechanical delay (EMD), defined as the time lag from muscle electrical activity to motion onset, has been proposed as a biomarker, but provides only limited insight in the pathophysiol-ogy of muscle function. This work proposes and...conference paper 2019
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Massaad Mouawad, J.M. (author), van Willigen, D.M. (author), van Neer, P.L.M.J. (author), de Jong, N. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author)Current ultrasonic clamp-on flow meters are based on single-element transducers that require manual calibration by aligning these to a fixed acoustic path. Moreover, the size and operational frequency of the transducers cannot be adapted to the parameters of the pipe and the liquid, which are in practice not precisely known a priory. A set of...conference paper 2019
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Fool, F. (author), Vos, H.J. (author), Shabanimotlagh, M. (author), Soozande, M. (author), Mozaffarzadeh, M. (author), Kim, T. (author), Kang, E. (author), Pertijs, M.A.P. (author), de Jong, N. (author), Verweij, M.D. (author)To accurately investigate the state of the carotid artery by the local haemodynamics and motion of the plaque using ultrasound, high-frame rate volumetric imaging is necessary. We have specifically designed a matrix array for this purpose. In this proceeding we will focus on imaging a volumetric flow profile using this matrix. For this...conference paper 2019
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Mozaffarzadeh, M. (author), Varnosfaderani, Mehdi H.H. (author), Sharma, Arunima (author), Pramanik, Manojit (author), de Jong, N. (author), Verweij, M.D. (author)In acoustic-resolution photoacoustic microscopy (AR-PAM) systems, the lateral resolution in the focal zone of the ultrasound (US) transducer is determined by the numerical aperture (NA) of the transducer. To have a high lateral resolution, a large NA is used. However, the larger the NA, the smaller the depth of focus [DOF]. As a result, the...journal article 2019