In vitro microglia models: the era of engineered cell microenvironments

The most widely employed approach by cell biologists to performing in vitro cell culture assays is the one using 2D plastic culture ware systems, which allows reproducibility and ease of use. Moreover, this method is cost-effective. However, in most cases, these flat surfaces lead to the formation of unrealistic 2D cell monolayers, which do not...

The Information Strategy Model: a framework for developing a monitoring strategy for national policy making and SDG6 reporting

Representatives from 14 countries worldwide worked together on improving their monitoring and ultimately their water management to reach the Sustainable Development Goal (SDG) 6 goals by 2030, thereby testing the Information Strategy Model (ISM). This model is developed to support identifying the need for information for water management. In...

Two-Photon Polymerization of 2.5D and 3D Microstructures Fostering a Ramified Resting Phenotype in Primary Microglia

Microglia are the resident macrophages of the central nervous system and contribute to maintaining brain’s homeostasis. Current 2D “petri-dish” in vitro cell culturing platforms employed for microglia, are unrepresentative of the softness or topography of native brain tissue. This often contributes to changes in microglial morphology, exhibiting...

Fatigue behaviour of a welded I-section under a concentrated compression (wheel) load

This paper deals with the evaluation of fatigue cracks under a concentrated compression (wheel) load in an I-section with full penetration welds between the web and flange. The objective is to investigate whether cracks stop or nearly stop when they have grown through the residual tensile stress field. These experimental investigations are...

H /e Superconducting Quantum Interference through Trivial Edge States in InAs

Josephson junctions defined in strong spin orbit semiconductors are highly interesting for the search for topological systems. However, next to topological edge states that emerge in a sufficient magnetic field, trivial edge states can also occur. We study the trivial edge states with superconducting quantum interference measurements on...

Fatigue behaviour of a welded I-section under a line load in compression

This paper is part of an evaluation of fatigue cracks in a crane runway girder with full penetration welds between the web and flange. The fatigue analysis of this actual crane runway girder is described in [1]. The investigation described in this paper deals with additional experimental tests on equivalent welded I sections on scale of...

Repairing Nanoparticle Surface Defects

Solar devices based on semiconductor nanoparticles require the use of conductive ligands; however, replacing the native, insulating ligands with conductive metal chalcogenide complexes introduces structural defects within the crystalline nanostructure that act as traps for charge carriers. We utilized atomically thin semiconductor...

Increased carrier generation rate in Si nanocrystals in SiO2 investigated by induced absorption

We report on investigations of optical generation of carriers in Si nanocrystals embedded in SiO2 matrix by time-resolved induced absorption technique. Results obtained for excitation below and above twice the bandgap energy h??<?2Eg and h??>?2Eg show very similar decay characteristics (within ?resolution ? 100 fs). When intensity of the signal...

Assessing Management Regimes in Transboundary River Basins: Do They Support Adaptive Management?

River basin management is faced with complex problems that are characterized by uncertainty and change. In transboundary river basins, historical, legal, and cultural differences add to the complexity. The literature on adaptive management gives several suggestions for handling this complexity. It recognizes the importance of management regimes...

Field-based scanning tunneling microscope manipulation of antimony dimers on Si(001)

Surface polymerization of epitaxial Sb wires on Si(001)