An exact optimization method for coordinating the arrival times of urban rail lines at a common corridor

The trips of a high-frequency urban rail line are typically planned with the aim of achieving even time headways. This results in reliable services for each urban rail line, where successive trips have the same time headway. Maintaining even time headways for each service line has significant advantages for the passengers of the line, but it...

A Capacitively Degenerated 100-dB Linear 20-150 MS/s Dynamic Amplifier

This paper presents a new dynamic residue amplifier topology for pipelined analog-to-digital converters. With an input signal of 100 mV_pp,diff and 4 × gain, it achieves-100-dB total harmonic distortion, the lowest ever reported for a dynamic amplifier. Compared to the state of the art, it exhibits 25 dB better linearity with twice...

A 66-dB SNDR Pipelined Split-ADC in 40-nm CMOS Using a Class-AB Residue Amplifier

This paper presents a closed-loop class-AB residue amplifier for pipelined analog-to-digital converters (ADCs). It consists of a push-pull structure with a ``split-capacitor'' biasing circuit that enhances its power efficiency. The amplifier is inherently quite linear, and so incomplete settling can be used to save power while still...

Intratumoral administration of Holmium-166 Acetylacetonate Microspheres: Antitumor efficacy and feasibility of multimodality imaging in renal cancer

The increasing incidence of small renal tumors in an aging population with comorbidities has stimulated the development of minimally invasive treatments. This study aimed to assess the efficacy and demonstrate feasibility of multimodality imaging of intratumoral administration of holmium-166 microspheres (166HoAcAcMS). This new technique locally...

Radioactive Holmium Acetylacetonate Microspheres for Interstitial Microbrachytherapy: An In Vitro and In Vivo Stability Study

Purpose The clinical application of holmium acetylacetonate microspheres (HoAcAcMS) for the intratumoral radionuclide treatment of solid malignancies requires a thorough understanding of their stability. Therefore, an in vitro and an in vivo stability study with HoAcAcMS was conducted. Methods HoAcAcMS, before and after neutron irradiation, were...

Holmium-166 poly(L-lactic acid) microsphere radioembolisation of the liver: Technical aspects studied in a large animal mode

Korte Termijn Advies Voedselreservering Oosterschelde: Samenvattende Rapportage in het kader van EVAII

Dit rapport is een uitgebreide samenvatting van de resultaten van een korte termijn studie naar de onderbouwing van het voedselreserveringsbeleid in de Oosterschelde. Detail informatie over gebruikte datasets, uitwerking van onderzoeksvragen, resultaten en referenties staan in het bijbehorende rapport 'Werkdocument Korte Termijn Advies...

Microspheres with Ultrahigh Holmium Content for Radioablation of Malignancies

Purpose The aim of this study was to develop microspheres with an ultra high holmium content which can be neutron activated for radioablation of malignancies. These microspheres are proposed to be delivered selectively through either intratumoral injections into solid tumors or administered via an intravascularly placed catheter. Methods...

Met lijnolie gemodificeerde alkylharsen: Onderzoekingen met behulp van fractioneren