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van Schaik, L. (author), Duives, D.C. (author), Hoogendoorn-Lanser, S. (author), Hoekstra, Jan Willem (author), Daamen, W. (author), Gavriilidou, A. (author), Krishnakumari, P.K. (author), Rinaldi, M. (author), Hoogendoorn, S.P. (author)
Physical distancing has been an important asset in limiting the SARS-CoV-2 virus spread during the COVID-19 pandemic. This study aims to assess compliance with physical distancing and to evaluate the combination of observed and self-reported data used. This research shows that it is difficult to operationalize new rules, that context affects...
journal article 2024
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Hoekstra, Mirjam E. (author), Slagter, Maarten (author), Urbanus, Jos (author), Toebes, Mireille (author), Slingerland, Nadine (author), de Rink, Iris (author), Kluin, Roelof J.C. (author), Nieuwland, Marja (author), Wessels, L.F.A. (author)
Cells in the tumor microenvironment (TME) influence each other through secretion and sensing of soluble mediators, such as cytokines and chemokines. While signaling of interferon γ (IFNγ) and tumor necrosis factor α (TNFα) is integral to anti-tumor immune responses, our understanding of the spatiotemporal behavior of these cytokines is...
journal article 2024
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Groot, D.J. (author), Ellerbroek, Joost (author), Hoekstra, J.M. (author)
Conventional Air Traffic Control is still predominantly being done by human Air Traffic Controllers, however, as the traffic density increases, the workload of the controllers increases as well. Especially for the area of unmanned aviation, driven by the rise in drones, having human controllers might become unfeasible. One of the methods that...
journal article 2024
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Meulah, Brice (author), Oyibo, P.O. (author), Hoekstra, Pytsje T. (author), Mour, Paul Alvyn Nguema (author), Maloum, Moustapha Nzamba (author), Laclong Lontchi, Roméo Aimé (author), Honkpehedji, Yabo Josiane (author), Bengtson, Michel (author), Hokke, Cornelis (author), Diehl, J.C. (author)
Introduction<br/>Schistosomiasis is a significant public health concern, especially in Sub-Saharan Africa. Conventional microscopy is the standard diagnostic method in resource-limited settings, but with limitations, such as the need for expert microscopists. An automated digital microscope with artificial intelligence (Schistoscope), offers a...
journal article 2024
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Hoekstra, J.S.C.M. (author), Gentili, M. (author)
For young adults on the Amsterdam housing market the accessibility of housing has been decreasing for years, due to soaring house prices and rents, the shrinkage and residualization of the social rental sector, and the precarization of the labor market. Consequently, many young people struggle to secure an affordable and adequate dwelling and...
journal article 2023
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Badea, C. (author), Morfin Veytia, A. (author), Patrinopoulou, Niki (author), Daramouskas, Ioannis (author), Ellerbroek, Joost (author), Lappas, Vaios (author), Kostopoulos, Vassilios (author), Hoekstra, J.M. (author)
The use of small aircraft for a wide range of missions in urban airspace is expected to increase in the future. In Europe, efforts have been invested into developing a unified system, called U-space, to manage aircraft in dense very-low-level urban airspace. The Metropolis II project aimed to research what degree of centralisation an air traffic...
journal article 2023
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Appel-Meulenbroek, Rianne (author), Voulon, Thijs (author), Bergefurt, Lisanne (author), Arkesteijn, M.H. (author), Hoekstra, B.S. (author), der Schaaf, Pity Jongens Van (author)
BACKGROUND: During the COVID-19 pandemic, office workers were obliged to work from home (WFH). Alongside known positive aspects of home-based telework, it is associated with reduced health and productivity impacts. Its success depends on employee and environmental characteristics. OBJECTIVE: This paper fills the gap in knowledge on the...
journal article 2023
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Morfin Veytia, A. (author), Badea, C. (author), Patrinopoulou, Niki (author), Daramouskas, Ioannis (author), Ellerbroek, Joost (author), Lappas, Vaios (author), Kostopoulos, Vassilios (author), Hoekstra, J.M. (author)
The interest in urban air mobility as a potential solution for urban congestion is steadily growing. Air operations in urban areas can present added complexity as compared with traditional air traffic management. As a result, it is necessary to test and develop novel airspace designs and rules. As airspace in urban areas is a scarce resource,...
journal article 2023
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Zoutendijk, M. (author), Mitici, M.A. (author), Hoekstra, J.M. (author)
Taxiing aircraft using electric towing vehicles (ETVs) is expected to significantly contribute to the objective of climate-neutral aviation by 2050. This study reviews existing work on operational aspects of electric towing of aircraft, and discusses management solutions. We first discuss the varying electric taxi systems currently under...
journal article 2023
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van Oosterom, S.J.M. (author), Mitici, M.A. (author), Hoekstra, J.M. (author)
Following the Paris Accords, the aviation industry aims to become climate neutral by 2050. In this line, electric vehicles that tow aircraft during taxiing are a promising emerging technology to reduce emissions at airports. This paper proposes an end-to-end optimization framework for electric towing vehicles (ETVs) dispatchment at large...
journal article 2023
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Wang, Zhengbing (author), Lodder, Q.J. (author), van der Spek, A.J.F. (author), Slinger, J (author), Hoekstra, Piet (author)
journal article 2023
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Roosenbrand, E.J. (author), Sun, Junzi (author), Hoekstra, J.M. (author)
As global flight volume rises, the aviation industry is facing increasing climate challenges. One major factor is the impact of contrails, which trap outgoing terrestrial radiation and counteract emission reduction benefits from emission-optimized flight routes. Our study quantifies contrail-forming flights globally and assesses altitude...
journal article 2023
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Patrinopoulou, Niki (author), Daramouskas, Ioannis (author), Badea, Calin Andrei (author), Morfin Veytia, A. (author), Lappas, Vaios (author), Ellerbroek, Joost (author), Hoekstra, J.M. (author), Kostopoulos, Vassilios (author)
Unmanned Aircraft Systems (UAS) Traffic Management (UTM) is an active research subject as its proposed applications are increasing. UTM aims to enable a variety of UAS operations, including package delivery, infrastructure inspection, and emergency missions. That creates the need for extensive research on how to incorporate such traffic, as...
journal article 2023
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Croon, T.M. (author), Hoekstra, J.S.C.M. (author), Elsinga, M.G. (author), Dalla Longa, F. (author), Mulder, Peter (author)
Recent energy price spikes have led to increased energy poverty among low-income households living in inefficient homes. Accurate statistics on energy poverty help inform resource allocation and better target relief schemes and retrofit funds. Existing indicators are predominantly defined in terms of a headcount ratio – the share of population...
journal article 2023
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Doole, M.M. (author), Ellerbroek, Joost (author), Hoekstra, J.M. (author)
Package delivery via autonomous drones is often presumed to hold commercial and societal value when applied to urban environments. However, to realise the benefits, the challenge of safely managing high traffic densities of drones in heavily constrained urban spaces needs to be addressed. This paper applies the principles of traffic segmentation...
journal article 2022
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Ribeiro, M.J. (author), Ellerbroek, Joost (author), Hoekstra, J.M. (author)
Current predictions on future drone operations estimate that traffic density orders of magnitude will be higher than any observed in manned aviation. Such densities redirect the focus towards elements that can decrease conflict rate and severity, with special emphasis on airspace structures, an element that has been overlooked within...
journal article 2022
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Ribeiro, M.J. (author), Ellerbroek, Joost (author), Hoekstra, J.M. (author)
Current predictions for future operations with drones estimate traffic densities orders of magnitude higher than any observed in manned aviation. Such densities call for further research and innovation, in particular, into conflict detection and resolution without the need for human intervention. The layered airspace concept, where aircraft...
journal article 2022
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Padmos, R.M. (author), Arrarte Terreros, Nerea (author), Józsa, Tamás I. (author), Závodszky, Gábor (author), Marquering, Henk A. (author), Majoie, Charles B.L.M. (author), Payne, Stephen J. (author), Hoekstra, Alfons G. (author)
The presence of collaterals and high thrombus permeability are associated with good functional outcomes after an acute ischaemic stroke. We aim to understand the combined effect of the collaterals and thrombus permeability on cerebral blood flow during an acute ischaemic stroke. A cerebral blood flow model including the leptomeningeal...
journal article 2022
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Ribeiro, M.J. (author), Ellerbroek, Joost (author), Hoekstra, J.M. (author)
Future high traffic densities with drone operations are expected to exceed the number of aircraft that current air traffic control procedures can control simultaneously. Despite extensive research on geometric CR methods, at higher densities, their performance is hindered by the unpredictable emergent behaviour from surrounding aircraft. In...
journal article 2022
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Ribeiro, M.J. (author), Ellerbroek, Joost (author), Hoekstra, J.M. (author)
Future operations involving drones are expected to result in traffic densities that are orders of magnitude higher than any observed in manned aviation. Current geometric conflict resolution (CR) methods have proven to be very efficient at relatively moderate densities. However, at higher densities, performance is hindered by the...
journal article 2022
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