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Van den Berg, B.A. (author), Reinders, M.J.T. (author), Hulsman, M. (author), Wu, L. (author), Pel, H.J. (author), Roubos, J.A. (author), De Ridder, D. (author)
Protein sequence features are explored in relation to the production of over-expressed extracellular proteins by fungi. Knowledge on features influencing protein production and secretion could be employed to improve enzyme production levels in industrial bioprocesses via protein engineering. A large set, over 600 homologous and nearly 2,000...
journal article 2012
document
van den Berg, B.A. (author), Reinders, M.J.T. (author), Pel, HJ (author), Roubos, J.A. (author), de Ridder, D. (author)
poster 2012
document
van den Berg, B.A. (author), Reinders, M.J.T. (author), Pel, HJ (author), Wu, L (author), Roubos, J.A. (author), de Ridder, D. (author)
Aspergillus niger is widely used for industrial enzyme production. Knowledge on high-level protein secretion could be useful to improve production rates. We used sequencebased classification methods to identify important properties<br/>for successful high-level secretion, which will be used to redesign proteins for improved secretion.
poster 2011