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Zhang, Tianyu (author), Ma, Yunjian (author), Tan, Chin Ping (author), Hollmann, F. (author), Wang, Jianrong (author), Yang, Bo (author), Wang, Yonghua (author)
was...
journal article 2019
document
Zhao, Ze Xin (author), Lan, Dongming (author), Tan, Xiyu (author), Hollmann, F. (author), Bornscheuer, Uwe T. (author), Yang, Bo (author), Wang, Yonghua (author)
in the past have mostly focused on...
journal article 2019
document
Dong, J. (author), Fernandez Fueyo, E. (author), Hollmann, F. (author), Paul, C.E. (author), Pesic, M. (author), Schmidt, S. (author), Wang, Yonghua (author), Younes, S.H.H. (author), Zhang, W. (author)
Oxidation chemistry using enzymes is approaching maturity and practical applicability in organic synthesis. Oxidoreductases (enzymes catalysing redox reactions) enable chemists to perform highly selective and efficient transformations ranging from simple alcohol oxidations to stereoselective halogenations of non‐activated C−H bonds. For many of...
journal article 2018
document
Hollmann, F. (author), Kara, S (author), Opperman, Diederik J. (author), Wang, Yonghua (author)
Cyclic esters and amides (lactones and lactams) are important active ingredients and polymer building blocks. In recent years, numerous biocatalytic methods for their preparation have been developed including enzymatic and chemoenzymatic Baeyer–Villiger oxidations, oxidative lactonisation of diols, and reductive lactonisation and...
journal article 2018
document
Liu, Nan (author), Liu, D. (author), Wang, Weifei (author), Hollmann, F. (author), Xu, Long (author), Ma, Yunjian (author), Yang, Bo (author), Bai, Weidong (author), Sun, Xiaotao (author), Wang, Yonghua (author)
α‐Linolenic acid‐rich diacylglycerol has been demonstrated with promising health promotion functions. This study examined the production, immobilization of lipase PCL, and its application in the synthesis of diacylglycerol by esterification of α‐linolenic acid with glycerol. The resin ECR8806 was selected as an effective support for the...
journal article 2018
document
Wang, Yonghua (author), Lan, Dongming (author), Durrani, Rabia (author), Hollmann, F. (author)
Peroxygenases are promising catalysts for preparative oxyfunctionalization chemistry as they combine the versatility of P450 monooxygenases with simplicity of cofactor-independent enzymes. Though many interesting applications have been reported, today ‘we have only scratched the surface’ and significant efforts are necessary to solve issues...
review 2017
document
Wang, Xu Ping (author), Zhou, Peng Fei (author), Li, Zhi Gang (author), Yang, Bo (author), Hollmann, F. (author), Wang, Yong Hua (author)
A Ser105Ala mutant of the lipase B from Candida antarctica enables 'perhydrolase-only' reactions. At the example of the chemoenzymatic Baeyer-Villiger oxidation of cyclohexanone, we demonstrate that with this mutant selective oxidation can be achieved in deep eutectic solvent while essentially eliminating the undesired hydrolysis reaction of...
journal article 2017
document
Zhou, Pengfei (author), Wang, Xuping (author), Zeng, Chaoxi (author), Wang, Weifei (author), Yang, Bo (author), Hollmann, F. (author), Wang, Yonghua (author)
journal article 2017
document
Lan, Dongming (author), Wang, Xuping (author), Zhou, Pengfei (author), Hollmann, F. (author), Wang, Yonghua (author)
journal article 2017
document
Zhou, Pengfei (author), Wang, Xuping (author), Yang, Bo (author), Hollmann, F. (author), Wang, Yonghua (author)
Epoxides are important synthetic intermediates for the synthesis of a broad range of industrial products. This study presents a promising solution to the current limitation of enzyme instability. By using simple deep eutectic solvents such as choline chloride/sorbitol, significant stabilization of the biocatalyst has been achieved leading to...
journal article 2017
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