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document
Deelen, C. (author)
report 1979
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Deelen, C. (author)
report 1980
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Deelen, C. (author)
report 1980
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Deelen, C. (author)
report 1980
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Deelen, C. (author)
report 1980
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Deelen, C. (author)
report 1981
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Vermeer, A.C.M. (author), Deelen, C. (author)
report 1981
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Deelen, C. (author)
report 1984
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Deelen, C. (author)
Voor het ontwerp van een dijk is het van belang in hoeverre de spreiding in de onderdelen die samen de kruinhoogte bepalen doorwerkt op het eindresultaat. Hierbij kan worden gedacht aan de onnauwkeurigheden in de natuurrandvoorwaarden zoals waterstands-, wind en golfkondities, maar ook aan de invloed van een bepaalde golfvoorspellingsmethode of...
report 1986
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Passtoors, W.M. (author), Boer, J.M. (author), Goeman, J.G. (author), Van den Akker, E.B. (author), Deelen, J. (author), Zwaan, B.J. (author), Scarborough, A. (author), Van der Breggen, R. (author), Vossen, R.H.A.M. (author)
The Leiden Longevity Study consists of families that express extended survival across generations, decreased morbidity in middle-age, and beneficial metabolic profiles. To identify which pathways drive this complex phenotype of familial longevity and healthy aging, we performed a genome-wide gene expression study within this cohort to screen for...
journal article 2012
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Deelen, T. (author)
master thesis 2013
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Deelen, M. (author)
master thesis 2013
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Passtoors, W.M. (author), Van den Akker, E.B. (author), Deelen, J. (author), Maier, A.B. (author), Van der Breggen, R. (author), Jansen, R. (author), Trompet, S. (author), Van Heemst, D. (author), Derhovanessian, E. (author), Pawelec, G. (author), Van Ommen, G.J.B. (author), Slagboom, P.E. (author), Beekman, M. (author)
journal article 2015
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Deelen, J (author), D., Evans (author), Dan E., Arking (author), Tesi, N. (author), M, Nygaard (author), Liu, Xiaoming (author), Mary K., Wojczynski (author), Reinders, M.J.T. (author), Holstege, H. (author)
Human longevity is heritable, but genome-wide association (GWA) studies have had limitedsuccess. Here, we perform two meta-analyses of GWA studies of a rigorous longevityphenotype definition including 11,262/3484 cases surviving at or beyond the age corre-sponding to the 90th/99th survival percentile, respectively, and 25,483 controls whose...
journal article 2019
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Deelen, Joris (author), Kettunen, Johannes (author), Fischer, Krista (author), van der Spek, Ashley (author), Trompet, Stella (author), Boyd, Andy (author), Zierer, Jonas (author), van den Akker, E.B. (author), Ala-Korpela, Mika (author)
Predicting longer-term mortality risk requires collection of clinical data, which is often cumbersome. Therefore, we use a well-standardized metabolomics platform to identify metabolic predictors of long-term mortality in the circulation of 44,168 individuals (age at baseline 18–109), of whom 5512 died during follow-up. We apply a stepwise ...
journal article 2019
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Beekman, Marian (author), Schutte, Bianca A.M. (author), van den Akker, E.B. (author), Noordam, Raymond (author), Dibbets-Schneider, Petra (author), de Geus-Oei, Lioe Fee (author), Deelen, Joris (author), Rest, Ondine van de (author), Heemst, Diana van (author)
Scope: Abdominal obesity is one of the main modifiable risk factors of age-related cardiometabolic disease. Cardiometabolic disease risk and its associated high abdominal fat mass, cholesterol, and glucose concentrations can be reduced by a healthier lifestyle. Hence, the aim is to understand the relation between lifestyle-induced changes in...
journal article 2020
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