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Kok, M.W.A. (author)
The microtubule cytoskeleton is an intracellular polymer network involved in cell shape, cell motility, and cell division. Microtubules are self-assembling, dynamic polymers composed of tubulin proteins that alternate between phases of growth and shrinkage, a behaviour known as “dynamic instability”. A key feature of microtubules is their...
doctoral thesis 2019
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Vittorietti, M. (author), Kok, Piet J.J. (author), Sietsma, J. (author), Jongbloed, G. (author)
Understanding the intricate and complex materials microstructure and how it is related to materials properties is an important problem in the Materials Science field. For a full comprehension of this relation, it is fundamental to be able to describe the main characteristics of the 3-dimensional microstructure. The most basic model used for...
journal article 2019
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Baltussen, Elisabeth J.M. (author), Brouwer de Koning, Susan G. (author), Sanders, J. (author), Aalbers, A.G.J. (author), Kok, N. F.M. (author), Beets, Geerard L. (author), Hendriks, B.H.W. (author), Sterenborg, Henricus J.C.M. (author), Kuhlmann, K. F.D. (author), Ruers, Theo J.M. (author)
Background: In colorectal cancer surgery there is a delicate balance between complete removal of the tumor and sparing as much healthy tissue as possible. Especially in rectal cancer, intraoperative tissue recognition could be of great benefit in preventing positive resection margins and sparing as much healthy tissue as possible. To better...
journal article 2019
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Curran, A.N. (author), de Bruijn, Karin M. (author), Klerk, W.J. (author), Kok, M. (author)
To make informed flood risk management (FRM) decisions in large protected river systems, flood risk and hazard analyses should include the potential for dike breaching. 'Load interdependency' analyses attempt to include the system-wide effects of dike breaching while accounting for the uncertainty of both river loads and dike fragility. The...
journal article 2019
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Girrbach, Fabian (author), Zandbergen, Raymond (author), Kok, M. (author), Hageman, Tijmen A.G. (author), Bellusci, Giovanni (author), Diehl, Moritz (author)
Inertial sensors are used in an increasing number of autonomous applications. Integrating such sensors into dynamic systems, the problem of their calibration arises naturally. Existing methods often require the sensor to be accurately placed in certain poses, which can be infeasible in practice. In this paper, we present an optimization-based...
conference paper 2019
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Nowka, Danny (author), Kok, M. (author), Seel, Thomas (author)
In inertial motion tracking of kinematic chains, inertial measurement units (IMUs) are attached to each segment in order to track their motion in three-dimensional space. Determining the relations between the functional axes of a joint and the local coordinate system of the attached sensor is a crucial requirement. For the case of hinge...
conference paper 2019
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Marijnissen, R.J.C. (author), Kok, M. (author), Kroeze, Carolien (author), van Loon-Steensma, J.M. (author)
It is not uncommon for a flood defence to be combined with other societal uses as a multifunctional flood defence, from housing in urban areas to nature conservation in rural areas. The assessment of the safety of multifunctional flood defences is often done using conservative estimates. This study synthesizes new probabilistic approaches to...
journal article 2019
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van der Krogt, M.G. (author), Schweckendiek, T. (author), Kok, M. (author)
One of the failure mechanisms of dikes is slope instability at the landward side. Often, one instability does not lead to flooding, and several successive instabilities are needed before the dike overtops, and erosion and breaching can occur, especially at lower water levels. In this paper we propose a method to estimate the probability of...
conference paper 2019
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Kok, M. (author), van de Riet, O. (author), Walker, W.E. (author)
Here we examine whether a study conducted 25 years ago (1992) would have had different conclusions if concepts and analytical methods developed since then had been used. The 1992 problem was to identify a strategy for reducing flood risk in the Netherlands by, for example, strengthening the river dikes against the risk of flooding. Since then,...
journal article 2019
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Sandberg, Evelien M. (author), Twijnstra, A.R.H. (author), van Meir, C. A. (author), Kok, H. S. (author), van Geloven, Nan (author), Gludovacz, K. (author), Kolkman, W. (author), Nagel, H.T.C. (author), Haans, L (author), Kapiteijn, K. (author), Jansen, F.W. (author)
Objective: To evaluate if immediate catheter removal (ICR) after laparoscopic hysterectomy is associated with similar retention outcomes compared with delayed removal (DCR). Study design: Non-inferiority randomised controlled trial. Population: Women undergoing laparoscopic hysterectomy in six hospitals in the Netherlands. Methods: Women were...
journal article 2019
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Kok, D.D. (author), Pande, S. (author), van Lier, J.B. (author), Ortigara, Angela R.C. (author), Savenije, H.H.G. (author), Uhlenbrook, S. (author)
Phosphorus is a nutrient necessary for the development of crops and is thus commonly applied as fertilizer to sustain agricultural production. It occurs naturally, in indefinite quantities of uncertain quality in phosphate rock formations, but also accumulates in urban and livestock wastewater wherefrom it is often lost as a pollutant....
journal article 2018
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Lendering, K.T. (author), Sebastian, A.G. (author), Jonkman, S.N. (author), Kok, M. (author)
The application of risk-based approaches for the design of flood infrastructure has become increasingly common in flood management. This approach, based on risk reduction and reliability, is used to assess the performance of conventional interventions (e.g., flood defences and dams) and to support decisions regarding their implementation....
journal article 2018
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Kok, D.D. (author), Pande, S. (author), Ortigara, Angela Renata Cordeiro (author), Savenije, H.H.G. (author), Uhlenbrook, S. (author)
Despite Africa controlling the vast majority of the global phosphate it also faces the greatest food shortages - partially due to a lack of access to the fertilizer market. A more accessible source of phosphorus comes from wastewater flows, which is currently lost through the discharge to open surface waters. Analysing the potential...
journal article 2018
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Tas, Roderick P. (author), Chen, Chiung Yi (author), Katrukha, Eugene A. (author), Vleugel, M. (author), Kok, M.W.A. (author), Dogterom, A.M. (author), Akhmanova, Anna (author), Kapitein, Lukas C. (author)
Force generation by molecular motors drives biological processes such as asymmetric cell division and cell migration. Microtubule gliding assays in which surface-immobilized motor proteins drive microtubule propulsion are widely used to study basic motor properties as well as the collective behavior of active self-organized systems....
journal article 2018
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Curran, A.N. (author), De Bruijn, K. M. (author), Kok, M. (author)
Hazard analysis is a crucial step in flood risk management, and for large rivers, the effects of breaches need to be taken into account. Hazard analyses that incorporate this overall “system behaviour” have become increasingly popular in flood risk assessment. Methods to perform such analyses often focus on high water levels as a trigger for...
journal article 2018
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Kok, M. (author), Solin, Arno (author)
We present a method for scalable and fully 3D magnetic field simultaneous localisation and mapping (SLAM) using local anomalies in the magnetic field as a source of position information. These anomalies are due to the presence of ferromagnetic material in the structure of buildings and in objects such as furniture. We represent the magnetic...
conference paper 2018
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van der Krogt, M.G. (author), Schweckendiek, T. (author), Kok, M. (author)
Transformation models are used to infer geotechnical properties from indirect measurements. A site-specific transformation model can be calibrated with direct and indirect measurements from a site. When such a model is used, then spatial variability, measurement errors and statistical uncertainty propagate into the uncertainty of the spatial...
journal article 2018
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Tümer, N. (author), Kok, A.C. (author), Vos, F.M. (author), Streekstra, Geert J. (author), Askeland, Christian (author), Tuijthof, G.J.M. (author), Zadpoor, A.A. (author)
A rigid surface–volume registration scheme is presented in this study to register computed tomography (CT) and free-hand tracked ultrasound (US) images of the talocrural joint. Prior to registration, bone surfaces expected to be visible in US are extracted from the CT volume and bone contours in 2D US data are enhanced based on monogenic signal...
journal article 2018
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Molnar, Marco (author), Kok, M. (author), Engel, Tilman (author), Kaplick, Hannes (author), Mayer, Frank (author), Seel, Thomas (author)
Low back pain (LBP) is a leading cause of activity limitation. Objective assessment of the spinal motion plays a key role in diagnosis and treatment of LBP. We propose a method that facilitates clinical assessment of lower back motions by means of a wireless inertial sensor network. The sensor units are attached to the right and left side of...
conference paper 2018
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Kok, R. (author), Vrijdag, A. (author), van 't Veer, A.P. (author), Abbink, D.A. (author)
Crew of small fast ships often experiences excessive vertical accelerations when sailing in waves, leading to discomfort and injuries. In an attempt to avoid this, experienced operators reduce speed voluntarily when they anticipate that the next vertical peak acceleration will be unacceptably large. However, at night and during excessive spray,...
conference paper 2018
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