Zhang, Y. (author), Luo, Liang (author), Ge, Jin (author), Yan, Su Qiong (author), Peng, Yan Xin (author), Liu, Ya Ru (author), Liu, Jin Xiang (author), Liu, C. (author), Ma, Tianqiong (author) An "on water" organocatalytic cyanoarylmethylation of aryl acetonitrile to isatins is developed, giving products in high yields and up to excellent diastereoselectivities. A remarkable enhancement of reaction rates and diastereoselectivities by water was observed under mild conditions. Moreover, this approach provides a highly efficient and...
journal article 2019
