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Zonneveld, Hazel I. (author), Pruim, R.H.R. (author), Bos, Daniel (author), Vrooman, Henri A. (author), Muetzel, Ryan L. (author), Hofman, Albert (author), Rombouts, Serge ARB (author), Niessen, W.J. (author), More Authors (author)
Structural brain markers are studied extensively in the field of neurodegeneration, but are thought to occur rather late in the process. Functional measures such as functional connectivity are gaining interest as potentially more subtle markers of neurodegeneration. However, brain structure and function are also affected by ‘normal’ brain...
journal article 2019
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Chaves Figueiredo, S. (author), Romero Rodriguez, C. (author), Ahmed, Zeeshan Y. (author), Bos, D. H. (author), Xu, Y. (author), Salet, Theo (author), Copuroglu, Oguzhan (author), Schlangen, E. (author), Bos, Freek P. (author)
New additive manufacturing methods for cementitious materials hold a high potential to increase automation in the construction industry. However, these methods require new materials to be developed that meet performance requirements related to specific characteristics of the manufacturing process. The appropriate characterization methods of...
journal article 2019
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Borg Costanzi, C. (author), Ahmed, Z. Y. (author), Schipper, H.R. (author), Bos, F. (author), Knaack, U. (author)
One of the geometrical restrictions associated with printed paste materials such as concrete, is that material must be self-supporting during printing. In this research paper a new methodology for 3D Printing Concrete onto a temporary freeform surface is presented. This is achieved by setting up a workflow for combining a Flexible Mould...
journal article 2018
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Khalilnezhad, H. (author), Popov, M. (author), van der Sluis, L. (author), Bos, Jorrit A. (author), de Jong, Jan P.W. (author), Ametani, A. (author)
Zero-missing is a phenomenon in shunt compensated cable systems in which the current through the line breaker does not cross the zero point for several cycles. This paper deals with a thorough investigation on countermeasures of the zero-missing phenomenon in transmission systems and determines the requirements, benefits, and risks of...
journal article 2018
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Bos, Boy Gustaaf Cornelis (author), Thoen, D.J. (author), Haalebos, E.A.F. (author), Gimbel, P. M.L. (author), Klapwijk, T.M. (author), Baselmans, J.J.A. (author), Endo, A. (author)
The superconducting critical temperature (T-\mathrm{c} > 15 K) of niobium titanium nitride (NbTiN) thin films allows for low-loss circuits up to 1.1 THz, enabling on-chip spectroscopy and multipixel imaging with advanced detectors. The drive for large-scale detector microchips is demanding NbTiN films with uniform properties over an...
journal article 2017
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Bos, R.A. (author), Plettenburg, D.H. (author)
The addition of a cosmetic glove to an upper limb prosthesis has a distinct effect on the cosmetic value, but its viscoelastic behaviour adds a substantial amount of stiffness and hysteresis to the system. As a result, the overall usability of the prosthesis is degraded. A novel negative stiffness element is designed to compensate for the...
journal article 2017
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Bos, R. (author), Bierbooms, W.A.A.M. (author)
An important problem in wind turbine design is the prediction of the 50-year load, as set by the IEC 61400-1 Design Load Case (DLC) 1.1. In most cases, designers work with limited simulation budgets and are forced to use extrapolation schemes to obtain the required return level. That this is no easy task is proven by the many studies dedicated...
journal article 2017
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Evans, Tavia E. (author), O'Sullivan, Michael J. (author), De Groot, Marius (author), Niessen, W.J. (author), Hofman, Albert (author), Krestin, Gabriel P. (author), Van Der Lugt, Aad (author), Portegies, Marileen L P (author), Koudstaal, Peter J. (author), Bos, Daniel (author), Vernooij, Meike W. (author), Ikram, Mohammad A. (author)
Background and Purpose - The presence of subclinical vascular brain disease, including white matter lesions and lacunar infarcts, substantially increases the risk of clinical stroke. White matter microstructural integrity is considered an earlier, potentially better, marker of the total burden of vascular brain disease. Its association with...
journal article 2016
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Bos, R. (author), Giyanani, A.H. (author), Bierbooms, W.A.A.M. (author)
Lidars have gained a lot of popularity in the field of wind energy, partly because of their potential to be used for wind turbine control. By scanning the oncoming wind field, any threats such as gusts can be detected early and high loads can be avoided by taking preventive actions. Unfortunately, lidars suffer from some inherent weaknesses that...
journal article 2016
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Bos, R.A. (author), Haarman, CJW (author), Stortelder, T. (author), Nizamis, K (author), Herder, J.L. (author), Stienen, AHA (author), Plettenburg, D.H. (author)
The development of dynamic hand orthoses is a fast-growing field of research and has resulted in many different devices. A large and diverse solution space is formed by the various mechatronic components which are used in these devices. They are the result of making complex design choices within the constraints imposed by the application, the...
journal article 2016
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Bos, R. (author), Veldkamp, D. (author)
An important yet difficult task in the design of wind turbines is to assess the extreme load behaviour, most notably finding the 50-year load. Where existing methods often focus on ways to extrapolate from small sample sizes, this paper proposes a different approach. It combines generating constrained gusts in turbulence fields, Delaunay...
journal article 2016
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Bomer, N. (author), Den Hollander, W.T.H.F. (author), Ramos, Y.F.M. (author), Bos, S.D. (author), Van der Breggen, R. (author), Lakenberg, N. (author), Pepers, B.A. (author), Van Eeden, A.E. (author), Darvishan, A. (author), Tobi, E.W. (author), Duijnisveld, B.J. (author), Van den Akker, E.B. (author), Heijmans, B.T. (author), Van Roon-Mom, W.M.C. (author), Verbeek, F.J. (author), Osch, G.J.V.M. (author), Nelissen, R.G.H.H. (author), Slagboom, P.E. (author), Meulenbelt, I. (author)
Objectives: To investigate how the genetic susceptibility gene DIO2 confers risk to osteoarthritis (OA) onset in humans and to explore whether counteracting the deleterious effect could contribute to novel therapeutic approaches. Methods: Epigenetically regulated expression of DIO2 was explored by assessing methylation of positional CpG...
journal article 2015
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Ikram, M.A. (author), Van der Lugt, A. (author), Niessen, W.J. (author), Koudstaal, P.J. (author), Krestin, G.P. (author), Hofman, A. (author), Bos, D. (author), Vernooij, M.W. (author)
Imaging plays an essential role in research on neurological diseases in the elderly. The Rotterdam Scan Study was initiated as part of the ongoing Rotterdam Study with the aim to elucidate the causes of neurological disease by performing imaging of the brain in a prospective population-based setting. Initially, in 1995 and 1999, random...
journal article 2015
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Bos, J. (author), De Jonge, N. (author), Veeke, H.P.M. (author)
Het in- en uitbesteden van bepalingen leidt tot een relatief grote werklast voor zowel het uitbestedende als inbestedende laboratorium. Het doel van het onderzoek was inzicht verkrijgen in de logistieke keten van orders in Nederland. Wij onderzochten de in- en uitbesteding door middel van observatie en interviews bij een drietal laboratoria, bij...
journal article 2014
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Bos, R. (author), Bierbooms, W. (author), Van Bussel, G. (author)
With the trend of moving towards 10-20MW turbines, rotor diameters are growing beyond the size of the largest turbulent structures in the atmospheric boundary layer. As a consequence, the fully uniform transients that are commonly used to predict extreme gust loads are losing their connection to reality and may lead to gross over dimensioning....
journal article 2014
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Van Tiel, J. (author), Reijman, M. (author), Bos, P.K. (author), Hermans, J. (author), Van Buul, G.M. (author), Bron, E.E. (author), Klein, S. (author), Verhaar, J.A.N. (author), Krestin, G.P. (author), Bierma-Zeinstra, S.M.A. (author), Weinans, H. (author), Kotek, G. (author), Oei, E.H.G. (author)
journal article 2013
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Slieker, R.C. (author), Bos, S.D. (author), Goeman, J.J. (author), Bovee, J.V.M.G. (author), Talens, R.P. (author), Van der Breggen, R. (author), Suchiman, H.E.D. (author), Lameijer, E.W. (author), Putter, H. (author), Van dern Akker, E.B. (author), Zhang, Y. (author), Jukema, J.W. (author), Slagboom, P.E. (author), Meulenbelt, I. (author), Heijmans, B.T. (author)
Background: DNA methylation has been recognized as a key mechanism in cell differentiation. Various studies have compared tissues to characterize epigenetically regulated genomic regions, but due to differences in study design and focus there still is no consensus as to the annotation of genomic regions predominantly involved in tissue-specific...
journal article 2013
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Van den Eeckhout, K. (author), Bos, A.J.J. (author), Poelman, D. (author), Smet, P.F. (author)
Persistent luminescence or afterglow is caused by a gradual release of charge carriers from trapping centers. The energy needed to release these charge carriers is determined by the trap depths. Knowledge of these trap depths is therefore crucial in the understanding of the persistent luminescence mechanism. Unfortunately, the trap depths in...
journal article 2013
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Argiolu, R. (author), Van der Heijden, R. (author), Bos, I. (author), Marchau, V.A.W.J. (author)
In recent years, a model was developed describing effects of Intelligent Transport Systems (ITS) on location preferences of office-keeping organisations in urbanised. The model is based on a Hierarchical Information Integration Approach, using Stated Preference data. The model indicates that ITS significantly contribute to office location...
journal article 2013
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Doets, M. (author), van der Voordt, D.J.M. (author), Bos, P. (author), Willemse, M. (author)
Het ASz bestaat uit ziekenhuizen in Sliedrecht, Zwijndrecht en Dordrecht. Bij het ASz mogen de patiënten de juiste zorg op het juiste moment en de juiste plaats met de juiste middelen door de juiste persoon met het juiste resultaat verwachten. Maar wat is juist? Als het gaat om (medisch inhoudelijke) kwaliteitseisen en normen, dan vertrouwen...
journal article 2012
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