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Vinke, Elisabeth J. (author), Huizinga, W. (author), Bergtholdt, Martin (author), Adams, Hieab H. (author), Steketee, Rebecca M.E. (author), Papma, Janne M. (author), De Jong, Frank Jan (author), Niessen, W.J. (author), Ikram, M. Arfan (author)
Brain imaging data are increasingly made publicly accessible, and volumetric imaging measures derived from population-based cohorts may serve as normative data for individual patient diagnostic assessment. Yet, these normative cohorts are usually not a perfect reflection of a patient's base population, nor are imaging parameters such as field...
journal article 2019
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Achterberg, Hakim C. (author), Sørensen, Lauge (author), Wolters, Frank J. (author), Niessen, W.J. (author), Vernooij, Meike W. (author), Ikram, M. Arfan (author), Nielsen, Mads (author), de Bruijne, Marleen (author)
Hippocampal volume and shape are known magnetic resonance imaging biomarkers of neurodegeneration. Recently, hippocampal texture has been shown to improve prediction of dementia in patients with mild cognitive impairment, but it is unknown whether texture adds prognostic information beyond volume and shape and whether the predictive value...
journal article 2019
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Vinke, Elisabeth J. (author), de Groot, Marius (author), Venkatraghavan, Vikram (author), Klein, S. (author), Niessen, W.J. (author), Ikram, M. Arfan (author), Vernooij, Meike W. (author)
With aging, the brain undergoes several structural changes. These changes reflect the normal aging process and are therefore not necessarily pathologic. In fact, better understanding of these normal changes is an important cornerstone to also disentangle pathologic changes. Several studies have investigated normal brain aging, both cross...
journal article 2018