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Starmans, M.P.A. (author), Miclea, Razvan L. (author), Vilgrain, Valerie (author), Ronot, Maxime (author), Purcell, Yvonne (author), Verbeek, Jef (author), Niessen, W.J. (author), Klein, Stefan (author), Thomeer, Maarten G. (author)Rationale and Objectives: Distinguishing malignant from benign liver lesions based on magnetic resonance imaging (MRI) is an important but often challenging task, especially in noncirrhotic livers. We developed and externally validated a radiomics model to quantitatively assess T2-weighted MRI to distinguish the most common malignant and...journal article 2024
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Benmahdjoub, Mohamed (author), Thabit, Abdullah (author), Van Veelen, Marie Lise C. (author), Niessen, W.J. (author), Wolvius, Eppo B. (author), Van Walsum, Theo (author)Augmented reality (AR) has shown potential in computer-aided surgery. It allows for the visualization of hidden anatomical structures as well as assists in navigating and locating surgical instruments at the surgical site. Various modalities (devices and/or visualizations) have been used in the literature, but few studies investigated the...journal article 2023
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Liu, Sijie (author), Xin, Jingmin (author), Wu, Jiayi (author), Deng, Yangyang (author), Su, Ruisheng (author), Niessen, W.J. (author), Zheng, Nanning (author), van Walsum, T. (author)Identification and detection of thin-cap fibroatheroma (TCFA) from intravascular optical coherence tomography (IVOCT) images is critical for treatment of coronary heart diseases. Recently, deep learning methods have shown promising successes in TCFA identification. However, most methods usually do not effectively utilize multi-view...journal article 2023
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Yilmaz, Pinar (author), Alferink, Louise J.M. (author), Cremers, Lotte G.M. (author), Murad, Sarwa D. (author), Niessen, W.J. (author), Ikram, M. Arfan (author), Vernooij, Meike W. (author)Background & Aims: Impaired liver function affects brain health and therefore understanding potential mechanisms for subclinical liver disease is essential. We assessed the liver–brain associations using liver measures with brain imaging markers, and cognitive measures in the general population. Methods: Within the population-based...journal article 2023
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Venkatraghavan, Vikram (author), Voort, Sebastian R.van der (author), Bos, Daniel (author), Smits, M. (author), Barkhof, Frederik (author), Niessen, W.J. (author), Klein, Stefan (author), Bron, Esther E. (author)Computer-aided methods have shown added value for diagnosing and predicting brain disorders and can thus support decision making in clinical care and treatment planning. This chapter will provide insight into the type of methods, their working, their input data –such as cognitive tests, imaging, and genetic data– and the types of output they...book chapter 2023
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Su, Jiahang (author), Li, Shuai (author), Wolff, Lennard (author), van Zwam, Wim (author), Niessen, W.J. (author), van der Lugt, Aad (author), van Walsum, T. (author)Extracting the cerebral anterior vessel tree of patients with an intracranial large vessel occlusion (LVO) is relevant to investigate potential biomarkers that can contribute to treatment decision making. The purpose of our work is to develop a method that can achieve this from routinely acquired computed tomography angiography (CTA) and...journal article 2023
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van der Voort, Sebastian R. (author), Incekara, Fatih (author), Wijnenga, Maarten M.J. (author), Kapsas, Georgios (author), Schouten, J.W. (author), French, P.J. (author), Niessen, W.J. (author), Smits, M. (author), Klein, Stefan (author)BACKGROUND: Accurate characterization of glioma is crucial for clinical decision making. A delineation of the tumor is also desirable in the initial decision stages but is time-consuming. Previously, deep learning methods have been developed that can either non-invasively predict the genetic or histological features of glioma, or that can...journal article 2023
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Niessen, S.E.M. (author), Groot, K.J. (author), Hickel, S. (author), Terrapon, Vincent E. (author)Linear stability analyses are performed to study the dynamics of linear convective instability mechanisms in a laminar shock-wave/boundary-layer interaction at Mach 1.7. In order to account for all two-dimensional gradients elliptically, we introduce perturbations into an initial-value problem that are found as solutions to an eigenvalue...journal article 2023
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Su, Ruisheng (author), van der Sluijs, P. Matthijs (author), Bobi, Joaquim (author), Taha, Aladdin (author), van Beusekom, Heleen M.M. (author), van der Lugt, Aad (author), Niessen, W.J. (author), Ruijters, Danny (author), van Walsum, T. (author)Background: X-ray digital subtraction angiography (DSA) is the imaging modality for peri-procedural guidance and treatment evaluation in (neuro-) vascular interventions. Perfusion image construction from DSA, as a means of quantitatively depicting cerebral hemodynamics, has been shown feasible. However, the quantitative property of perfusion...journal article 2023
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Liu, X. (author), Kayser, Manfred (author), Kushner, S.A. (author), Tiemeier, H (author), Rivadeneira, F (author), Jaddoe, Vincent (author), Niessen, W.J. (author), Wolvius, E.B. (author), Roshchupkin, G.V. (author)STUDY QUESTION: Is there an association between low-to-moderate levels of prenatal alcohol exposure (PAE) and children's facial shape? SUMMARY ANSWER: PAE before and during pregnancy, even at low level (<12 g of alcohol per week), was found associated with the facial shape of children, and these associations were found attenuated as...journal article 2023
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Abdel-Alim, Tareq (author), Kurniawan, Melissa (author), Mathijssen, Irene (author), Dremmen, Marjolein (author), Dirven, Clemens (author), Niessen, W.J. (author), Roshchupkin, Gennady (author), Van Veelen, Marie Lise (author)Background: The aim of this study was to compare three surgical interventions for correction of sagittal synostosis-frontobiparietal remodeling (FBR), extended strip craniotomy (ESC), and spring-Assisted correction (SAC)-based on three-dimensional (3D) photogrammetry and operation characteristics. Methods: Patients who were born between 1991...journal article 2023
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Benmahdjoub, Mohamed (author), Niessen, W.J. (author), Wolvius, Eppo B. (author), van Walsum, T. (author)Augmented reality (AR) permits the visualization of pre-operative data in the surgical field of view of the surgeon. This requires the alignment of the AR device’s coordinate system with the used navigation/tracking system. We propose a multimodal marker approach to align an AR device with a tracking system: in our implementation, an...journal article 2022
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Starmans, Martijn P.A. (author), Timbergen, Milea J.M. (author), Vos, Melissa (author), Renckens, Michel (author), Grünhagen, Dirk J. (author), van Leenders, Geert J.L.H. (author), Niessen, W.J. (author), Visser, Jacob J. (author), Klein, Stefan (author)Treatment planning of gastrointestinal stromal tumors (GISTs) includes distinguishing GISTs from other intra-abdominal tumors and GISTs’ molecular analysis. The aim of this study was to evaluate radiomics for distinguishing GISTs from other intra-abdominal tumors, and in GISTs, predict the c-KIT, PDGFRA, BRAF mutational status, and mitotic...journal article 2022
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Castillo, J.M. (author), Arif, M. (author), Starmans, M.P.A. (author), Niessen, W.J. (author), Bangma, C.H. (author), Schoots, Ivo G. (author), Veenland, J.F. (author)The computer-aided analysis of prostate multiparametric MRI (mpMRI) could improve significant-prostate-cancer (PCa) detection. Various deep-learning-and radiomics-based methods for significant-PCa segmentation or classification have been reported in the literature. To be able to assess the generalizability of the performance of these methods,...journal article 2022
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Su, Ruisheng (author), van der Sluijs, Matthijs (author), Cornelissen, Sandra A.P. (author), Lycklama, Geert (author), Hofmeijer, Jeannette (author), Majoie, Charles B.L.M. (author), Niessen, W.J. (author), van der Lugt, Aad (author), van Walsum, T. (author)Intracranial vessel perforation is a peri-procedural complication during endovascular therapy (EVT). Prompt recognition is important as its occurrence is strongly associated with unfavorable treatment outcomes. However, perforations can be hard to detect because they are rare, can be subtle, and the interventionalist is working under time...journal article 2022
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Su, Jiahang (author), Wolff, Lennard (author), van Doormaal, Pieter Jan (author), Dippel, Diederik W.J. (author), van Zwam, Wim (author), Niessen, W.J. (author), van der Lugt, Aad (author), van Walsum, T. (author)Purpose: The assessment of collateral status may depend on the timing of image acquisition. The purpose of this study is to investigate whether there are optimal time points in CT Perfusion (CTP) for collateral status assessment, and compare collaterals scores at these time points with collateral scores from multiphase CT angiography (mCTA)....journal article 2022
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Thabit, Abdullah (author), Benmahdjoub, Mohamed (author), van Veelen, Marie Lise C. (author), Niessen, W.J. (author), Wolvius, Eppo B. (author), van Walsum, T. (author)Purpose: In minimally invasive spring-assisted craniectomy, surgeons plan the surgery by manually locating the cranial sutures. However, this approach is prone to error. Augmented reality (AR) could be used to visualize the cranial sutures and assist in the surgery planning. The purpose of our work is to develop an AR-based system to...journal article 2022
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Thabit, Abdullah (author), Niessen, W.J. (author), Wolvius, Eppo B. (author), van Walsum, T. (author)Optical-based navigation systems are widely used in surgical interventions. However, despite their great utility and accuracy, they are expensive and require time and effort to setup for surgeries. Moreover, traditional navigation systems use 2D screens to display instrument positions causing the surgeons to look away from the operative field...conference paper 2022
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Starmans, Martijn P.A. (author), Buisman, Florian E. (author), Renckens, Michel (author), Willemssen, François E.J.A. (author), van der Voort, Sebastian R. (author), Groot Koerkamp, B. (author), Grünhagen, Dirk J. (author), Niessen, W.J. (author), Vermeulen, Peter B. (author)Histopathological growth patterns (HGPs) are independent prognosticators for colorectal liver metastases (CRLM). Currently, HGPs are determined postoperatively. In this study, we evaluated radiomics for preoperative prediction of HGPs on computed tomography (CT), and its robustness to segmentation and acquisition variations. Patients with...journal article 2021
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Niessen, W.J. (author), Hofer, Edith (author), Roshchupkin, Gennady (author), Adams, Hieab H.H. (author), Knol, Maria J. (author), Lin, Honghuang (author), Li, Shuo (author), Zare, Habil (author), shazad, Ahmad (author)Cortical thickness, surface area and volumes (MRI cortical measures) vary with age and cognitive function, and in neurological and psychiatric diseases. We examined heritability, genetic correlations and genome-wide associations of cortical measures across the whole cortex, and in 34 anatomically predefined regions. Our discovery sample...working paper 2021