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Wu, J. (author), Sigmund, Ole (author), Groen, Jeroen P. (author)
Multi-scale structures, as found in nature (e.g., bone and bamboo), hold the promise of achieving superior performance while being intrinsically lightweight, robust, and multi-functional. Recent years have seen a rapid development in topology optimization approaches for designing multi-scale structures, but the field actually dates back to...
review 2021
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Cuellar Lopez, J.S. (author), Smit, G. (author), Plettenburg, D.H. (author), Zadpoor, A.A. (author)
Fabrication of complex and multi-articulated mechanisms is often seen as a time consuming and demanding process. The development of functional multi-articulated mechanisms that could be fabricated in a single step without the need for post-manufacturing assembly is therefore very attractive. Additive manufacturing (AM) has been pointed out as...
review 2018
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Culmone, C. (author), Smit, G. (author), Breedveld, P. (author)
Goal: Additive manufacturing, also known as 3D printing, has begun to play a significant role in the field of medical devices. This review aims to provide a comprehensive overview and classification of additively manufactured medical instruments for diagnostics and surgery by identifying medical and technical aspects. Methods: A scientific...
review 2019
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Lussenburg, K.M. (author), Sakes, A. (author), Breedveld, P. (author)
Additive Manufacturing (AM) or 3D printing has enabled the production of increasingly complex parts that are difficult to produce with conventional manufacturing methods. Its additive nature has made it possible to create interlocking parts in a single production step. This creates opportunities for new ways of designing and producing...
review 2021
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Li, Yageng (author), Shi, Yixuan (author), Lu, Yuchen (author), Li, Xuan (author), Zhou, J. (author), Zadpoor, A.A. (author), Wang, Luning (author)
With the advancement of additive manufacturing (AM), customized vascular stents can now be fabricated to fit the curvatures and sizes of a narrowed or blocked blood vessel, thereby reducing the possibility of thrombosis and restenosis. More importantly, AM enables the design and fabrication of complex and functional stent unit cells that...
review 2023
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Bayat, Mohamad (author), Zinovieva, Olga (author), Ferrari, Federico (author), Ayas, C. (author), Langelaar, Matthijs (author), Spangenberg, Jon (author), Salajeghe, Roozbeh (author), Poulios, Konstantinos (author), Mohanty, Sankhya (author), Sigmund, Ole (author), Hattel, Jesper (author)
Additive manufacturing (AM) processes have proven to be a perfect match for topology optimization (TO), as they are able to realize sophisticated geometries in a unique layer-by-layer manner. From a manufacturing viewpoint, however, there is a significant likelihood of process-related defects within complex geometrical features designed by TO...
review 2023
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Li, Y. (author), Jahr, H. (author), Zhou, J. (author), Zadpoor, A.A. (author)
Partially due to the unavailability of ideal bone substitutes, the treatment of large bony defects remains one of the most important challenges of orthopedic surgery. Additively manufactured (AM) biodegradable porous metals that have emerged since 2018 provide unprecedented opportunities for fulfilling the requirements of an ideal bone...
review 2020
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Putra, N.E. (author), Mirzaali, Mohammad J. (author), Apachitei, I. (author), Zhou, J. (author), Zadpoor, A.A. (author)
The growing interest in multi-functional metallic biomaterials for bone substitutes challenges the current additive manufacturing (AM, =3D printing) technologies. It is foreseeable that advances in multi-material AM for metallic biomaterials will not only allow for complex geometrical designs, but also improve their multi-functionalities by...
review 2020
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Laan, Rianne (author), Nout, Remi A. (author), Dankelman, J. (author), van de Berg, N.J. (author)
Background:<br/> Brachytherapy involves placement of radioactive sources inside or near the tumour. For gynaecological cancer, recent developments, including 3D imaging and image-guided adaptive brachytherapy, have improved treatment quality and outcomes. However, for large or complex tumours, target coverage and local control with commercially...
journal article 2019
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Hakkaart, X.D.V. (author), Pronk, J.T. (author), van Maris, A.J.A. (author)
Understanding microbial growth and metabolism is a key learning objective of microbiology and biotechnology courses, essential for understanding microbial ecology, microbial biotechnology and medical microbiology. Chemostat cultivation, a key research tool in microbial physiology that enables quantitative analysis of growth and metabolism under...
journal article 2017
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Bekker, A.C.M. (author), Verlinden, J.C. (author)
Wire and Arc Additive Manufacturing (WAAM) is a metal 3D printing technique based on robotic welding. This technique yields potential in decreasing material consumption due to its high material efficiency and freedom of shape. Empirical measurements of WAAM, using a deposition rate of 1 kg/h, were performed on site of MX3D. The measured power...
journal article 2018
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Li, Y. (author), Zhou, J. (author), Pavanram, P. (author), Leeflang, M.A. (author), Fockaert, L.I. (author), Pouran, B. (author), Tümer, N. (author), Schröder, K. U. (author), Mol, J.M.C. (author), Weinans, Harrie (author), Jahr, H. (author), Zadpoor, A.A. (author)
An ideal bone substituting material should be bone-mimicking in terms of mechanical properties, present a precisely controlled and fully interconnected porous structure, and degrade in the human body to allow for full regeneration of large bony defects. However, simultaneously satisfying all these three requirements has so far been highly...
journal article 2017
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Hille, Helge C. (author), Kumar, Siddhant (author), De Lorenzis, Laura (author)
We propose Floating Isogeometric Analysis (FLIGA), which extends IGA to extreme deformation analysis. The method is based on a novel tensor-product construction of B-Splines for the update of the basis functions in one direction of the parametric space. With basis functions “floating” deformation-dependently in this direction, mesh distortion...
journal article 2022
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Pfarr, Daniel (author), Louter, P.C. (author)
The use of thin glass promises to enable a variety of construction industry pursuits. In addition to the ecological benefits of more efficient use of resources, architects can anticipate new design freedoms with thin glass. Based on the sandwich theory, the flexible thin glass can be combined with a 3D-printed open-cell polymer core to form a...
journal article 2023
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Setaki, F. (author), Tian, F. (author), Turrin, M. (author), Tenpierik, M.J. (author), Nijs, L. (author), van Timmeren, A. (author)
This paper discusses a novel, compact sound absorption solution with high performance at various frequencies, including low frequencies, achieved through the effective use of Computational Design and Additive Manufacturing (AM). Sound absorption is widely applied for reducing noise and improving room acoustics; however, it is often constrained...
journal article 2023
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Sobota, V.C.M. (author), van de Kaa, G. (author), Luomaranta, Toni (author), Martinsuo, Miia (author), Ortt, J.R. (author)
Purpose: This paper addresses the most important factors for the selection of additive manufacturing (AM) technology as a method of production of metal parts. AM creates objects by adding material layer by layer based on 3D models. At present, interest in AM is high as it is hoped that AM contributes to the competitiveness of Western...
journal article 2020
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Dong, J. (author), Tümer, N. (author), Leeflang, M.A. (author), Taheri, P. (author), Fratila-Apachitei, E.L. (author), Mol, J.M.C. (author), Zadpoor, A.A. (author), Zhou, J. (author)
Porous biodegradable Mg and its alloys are considered to have a great potential to serve as ideal bone substitutes. The recent progress in additive manufacturing (AM) has prompted its application to fabricate Mg scaffolds with geometrically ordered porous structures. Extrusion-based AM, followed by debinding and sintering, has been recently...
journal article 2022
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van de Ven, E.A. (author), Maas, Robert (author), Ayas, C. (author), Langelaar, Matthijs (author), van Keulen, A. (author)
Although additive manufacturing (AM) allows for a large design freedom, there are some manufacturing limitations that have to be taken into consideration. One of the most restricting design rules is the minimum allowable overhang angle. To make topology optimization suitable for AM, several algorithms have been published to enforce a minimum...
journal article 2021
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Oldhoff, M. G.E. (author), Mirzaali, Mohammad J. (author), Tümer, N. (author), Zhou, J. (author), Zadpoor, A.A. (author)
Additive manufacturing (AM) offers great design freedom that enables objects with desired unique and complex geometry and topology to be readily and cost-effectively fabricated. The overall benefits of AM are well known, such as increased material and resource efficiency, enhanced design and production flexibility, the ability to create...
journal article 2021
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Kerstens, Fabio (author), Cervone, A. (author), Gradl, P.R. (author)
High performance liquid rocket engines require cooling to maintain structural integrity of the combustion chamber which is exposed to high thermal and environmental loads. For many systems, this is achieved by means of regenerative cooling, where a coolant flows through passages around the chamber wall whilst extracting heat from the wall. A...
journal article 2021
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