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Isaakidou, A. (author), Ganjian, M. (author), van Hoften, R. (author), Cruz Saldivar, M. (author), Leeflang, M.A. (author), Groetsch, A. (author), Wątroba, M. (author), Schwiedrzik, J. (author), Mirzaali, Mohammad J. (author), Apachitei, I. (author), Fratila-Apachitei, E.L. (author), Zadpoor, A.A. (author)The currently available treatments for inner ear disorders often involve systemic drug administration, leading to suboptimal drug concentrations and side effects. Cochlear implants offer a potential solution by providing localized and sustained drug delivery to the cochlea. While the mechanical characterization of both the implants and their...journal article 2024
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de Winter, Jikke (author), Manzaneque Garcia, T. (author), Ghatkesar, M.K. (author)The emerging high-resolution 3D printing technique called two-photon polymerization (2PP) enables to print devices bottom-up rapidly, contrary to the top-down lithography-based fabrication methods. In this work, various polymer microbeams are 3D printed and their resonant characteristics are analyzed to understand the origin of damping. The...journal article 2024
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de Vries, Sietse (author), Schuller, Tomás (author), Galindo-Rosales, Francisco J. (author), Fanzio, P. (author)Fused Filament Fabrication is an additive manufacturing technique in which molten thermoplastic polymers are extruded through a nozzle. Therefore, the interplay between the viscoelastic nature of the polymer melt, temperature, printing conditions and nozzle shape may lead to inconsistent extrusion. To improve the extrusion control and...journal article 2024
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Salandova, M. (author), Leeflang, M.A. (author), Klimopoulou, M. (author), Fratila-Apachitei, E.L. (author), Apachitei, I. (author), Zadpoor, A.A. (author)This study proposes a new concept for an on-demand drug releasing device intended for integration into additively manufactured (i.e., 3D printed) orthopedic implants. The system comprises a surface with conduits connected to a subsurface reservoir used for storage and on-demand release of antimicrobial agents, covered with a cap that prevents...journal article 2024
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Trauzettel, F. (author), Vander Poorten, Emmanuel (author), Ourak, Mouloud (author), Dankelman, J. (author), Breedveld, P. (author)While articulated surgical instruments have enabled the proliferation of minimally invasive interventions, procedures such as laparo-endoscopic single-site surgery are waning in popularity. One potential reason for this decline is a lack of sufficiently dexterous instruments. Although multi-steerable instruments exist, these are often complex...journal article 2024
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Mohammadi, Kaivan (author), Shafia, Moein (author), Akbari, Javad (author), Hedayati, R. (author)Pentamodes (first conceived theoretically by Milton and Cherkaev) are a very interesting class of mechanical metamaterials that can be used as building blocks of structures withdecoupled bulk and shear moduli. The pentamodes usually are composed of double cone-shaped struts with the middle diameter being large and the end diameters being tiny...journal article 2024
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de Jong, P.H. (author), Salvatori, Y.S. (author), Libonati, F. (author), Mirzaali, Mohammad J. (author), Zadpoor, A.A. (author)Shape morphing is the ability of objects to adapt to different shapes and reduce stress concentrations through increased contact area. This is a common trait of natural and engineered objects and has several applications in, among others, soft robotics and orthopedic implants. Shape morphing is achieved through flexible materials or rigid...journal article 2023
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Setaki, F. (author), Tian, F. (author), Turrin, M. (author), Tenpierik, M.J. (author), Nijs, L. (author), van Timmeren, A. (author)This paper discusses a novel, compact sound absorption solution with high performance at various frequencies, including low frequencies, achieved through the effective use of Computational Design and Additive Manufacturing (AM). Sound absorption is widely applied for reducing noise and improving room acoustics; however, it is often constrained...journal article 2023
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Fugazzola, Maria C. (author), Golafshan, Nasim (author), van Aken, Joris A. (author), Plomp, S. (author), De Grauw, Janny (author), van Buul, Ward (author), Hermsen, Gied (author), Weinans, Harrie (author), Castilho, Miguel (author), van Weeren, René (author), Malda, Jos (author)Summary: The objective of this study was to evaluate a non-resorbable implant for the focal repair of osteochondral defects. Enhanced adherence of repair cartilage overgrowing the implants was the secondary goal and was tested by introducing porosities on the articular surface of the implant. This study evaluated four versions of the...journal article 2023
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Shikh Anuar, Fadhilah (author), Mustapha, Khairul Azhar (author), Sa'at, Fatimah Al Zahrah Mohd (author), Zini, Nurul Hilwa Mohd (author), Tokit, Ernie Mat (author), Narasimmanaidu, Satishwara Rao (author), Hooman, K. (author)In this study, the microstructure of open-cell metal foam was generated and reconstructed, to produce a new generation of open-cell foam, which is called 3D printed open-cell foam. At the current stage of research, nylon powder and plastic acid are utilized as the materials for two different 3D printing technologies: Selective Laser Sintering...journal article 2023
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Khatami, Mohamad (author), Doniavi, Ali (author), Abazari, Amir Musa (author), Fotouhi, M. (author)This paper presents a new design strategy to improve the flexibility and strength-to-weight ratio of polymeric stents. The proposed design introduces a variable-thickness (VT) stent that outperforms conventional polymeric stents with constant thickness (CT). While polymeric stents offer benefits like flexibility and bioabsorption, their...journal article 2023
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Oh, J.J. (author), Ammu, S.K. (author), Vriend-Harwig, V.D. (author), Kieffer, R.Y. (author), Dr. Kleiner, F.K. (author), Balasubramanian, S. (author), Karana, E. (author), Masania, K. (author), Aubin-Tam, M.E. (author)Engineered living materials (ELMs) are a novel class of functional materials that typically feature spatial confinement of living components within an inert polymer matrix to recreate biological functions. Understanding the growth and spatial configuration of cellular populations within a matrix is crucial to predicting and improving their...journal article 2023
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Xu, Y. (author), Šavija, B. (author)Auxetic cementitious composites (ACCs) with improved mechanical properties are created, by casting 3D printed polymeric auxetic reinforcement structures inside cementitious mortar. Four types of ACCs incorporating reinforcement with different auxetic mechanisms were prepared: “re-entrant” (RE), “rotating-square” (RS), “chiral” (CR) and ...journal article 2023
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Bierach, C.B. (author), Alberts Coelho, A.A.C. (author), Turrin, M. (author), Așut, Serdar (author), Knaack, U. (author)Under urgent sustainability targets, the building industry craves for renewable and recyclable biomaterials as cellulose is a fiber; Lignin is a plant-derived low-cost polymer with remarkable properties, yet its valorization is in its infancy. Recent studies have shown potentials to combine cellulose and lignin into a renewable bio-based...journal article 2023
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Hedayati, R. (author), Yousefi, Armin (author), Dezaki, Mohammadreza Lalegani (author), Bodaghi, Mahdi (author)Both 2D and 3D re-entrant designs are among the well-known prevalent auxetic structures exhibiting negative Poisson's ratio. The present study introduces novel analytical relationships for 2D re-entrant hexagonal honeycombs for both negative and positive ranges of the cell interior angle θ (θ<0 showing a negative Poisson's ratio). The...journal article 2023
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Hedayati, R. (author), Stulova, Victoria (author)Due to payload weight limitations and human vulnerability to harsh space conditions, it is preferable that the potential landing location for humans has an already constructed habitat preferably made from in situ materials. Therefore, the prospect of utilizing a readily available Martian material, such as regolith, in an easily programmable...journal article 2023
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Xu, Y. (author), Šavija, B. (author)A composite can have properties much better than the components it is made of. This work proposes a three-dimensional auxetic cementitious-polymeric composite structure (3D-ACPC) which incorporates 3D printed polymeric shell with cementitious mortar. Uniaxial compression experiments are performed on the 3D-ACPC to study their quasi-static...journal article 2023
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van Kootwijk, A. (author), Jonker, B. P. (author), Wolvius, E. B. (author), Cruz Saldivar, M. (author), Leeflang, M.A. (author), Zhou, J. (author), Tümer, N. (author), Mirzaali, Mohammad J. (author), Zadpoor, A.A. (author)Objective: Mandibular reconstruction using patient-specific cage implants is a promising alternative to the vascularized free flap reconstruction for nonirradiated patients with adequate soft tissues, or for patients whose clinical condition is not conducive to microsurgical reconstruction. This study aimed to assess the biomechanical...journal article 2023
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Wan, Z. (author), Xu, Y. (author), He, S. (author), Chen, Y. (author), Xie, J. (author), Šavija, B. (author)Direct ink writing of cementitious materials can be an alternative way for creating vascular self-healing concrete by intentionally incorporating hollow channels in the cementitious matrix. In this study, a 3D-printable fibre reinforced mortar was first developed. Three groups of specimens were fabricated using direct ink writing, where the...journal article 2023
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Blankespoor, Maarten (author), Manzaneque Garcia, T. (author), Ghatkesar, M.K. (author)The capacity to precisely pipette femtoliter volumes of liquid enables many applications, for example, to functionalize a nanoscale surface and manipulate fluids inside a single-cell. A pressure-controlled pipetting method is the most preferred, since it enables the widest range of working liquids. However, precisely controlling femtoliter...journal article 2023