- document
-
Nechemia-Arbely, Yael (author), Fachinetti, Daniele (author), Miga, Karen H. (author), Sekulic, Nikolina (author), Soni, G.V. (author), Kim, Dong Hyun (author), Wong, Adeline K. (author), Lee, Ah Young (author), Nguyen, Kristen (author), Dekker, C. (author), Ren, Bing (author), Black, Ben E. (author), Cleveland, Don W. (author)Chromatin assembled with centromere protein A (CENP-A) is the epigenetic mark of centromere identity. Using new reference models, we now identify sites of CENP-A and histone H3.1 binding within the megabase, α-satellite repeat-containing centromeres of 23 human chromosomes. The overwhelming majority (97%) of α-satellite DNA is found to be...journal article 2017
- document
-
Choi, Da Som (author), Ni, Y. (author), Fernandez Fueyo, E. (author), Lee, Minah (author), Hollmann, F. (author), Park, Chan Beum (author)Peroxygenases are very promising catalysts for oxyfunctionalization reactions. Their practical applicability, however, is hampered by their sensitivity against the oxidant (H<sub>2</sub>O<sub>2</sub>), therefore necessitating in situ generation of H<sub>2</sub>O<sub>2</sub>. Here, we report a photoelectrochemical approach to provide...journal article 2017
- document
- Lee, Jae-Hoon (author), Kim, Younghwan (author) journal article 2017
- document
-
Lee, O.Z.A. (author), Dialynas, G. (author), de Winter, J.C.F. (author), Happee, R. (author), Schwab, A.L. (author)Recent years have seen an increase in cycling as a transport mode in urban centers. This has spurred an interest in the use of bicycle simulators to study cyclist behavior [1, 2, 3, 4]. However, few implement a model based approach that couples the bicycle roll and steer in a realistic manner [5]. Balancing is a key task in cycling and we aimed...conference paper 2017
- document
-
Lee, Ying-Chieh (author), Ko, Chia-Ying (author), Lin, Y. (author), Wang, Chi-Yun (author), Huang, Chun-Wei (author), Seto, Karen C. (author)Eight East Asian countries are home to approximately one-quarter of the world’s urban population, and by 2050, the combined urban population of these countries is expected to increase to 1.29 billion from 881 million today. Thus a central challenge for East Asian cities is how to pursue more low-carbon urbanization pathways. One of the key...conference paper 2017
- document
-
Chang, Joonho (author), Jung, Kihyo (author), Lee, W. (author), You, Heecheon (author)The present study developed and tested a new usability evaluation method which considers natural product-use motions. The proposed method measures both natural product-use motions (NMs) and actual product-use motions (AMs) for a product using an optical motion capture system and examines the usability of the product based on motion similarity...journal article 2017
- document
-
Lajoinie, Guillaume (author), Lee, Jeong Yu (author), Owen, Joshua (author), Kruizinga, P. (author), de Jong, N. (author), Van Soest, Gijs (author), Stride, Eleanor (author), Versluis, Michel (author)Photoacoustic (PA) imaging offers several attractive features as a biomedical imaging modality, including excellent spatial resolution and functional information such as tissue oxygenation. A key limitation, however, is the contrast to noise ratio that can be obtained from tissue depths greater than 1-2 mm. Microbubbles coated with an...journal article 2017
- document
-
Mocci, J. (author), Cua, M. (author), Lee, S. (author), Jian, Y (author), Pozzi, P. (author), Quintavalla, M. (author), Trestino, C. (author), Verstraete, H.R.G.W. (author), Wahl, D. (author), Muradore, R. (author), Zawadzki, R.J. (author), Verhaegen, M.H.G. (author), Sarunic, M.V. (author), Bonora, S. (author)The use of adaptive lenses instead of deformable mirrors can simplify the implementation of an adaptive optics system. The recently introduced Multi-actuator Adaptive Lens (MAL) can be used in closed loop with a wavefront sensor to correct for time-variant wavefront aberrations. The MAL can guarantee a level of correction and a response time...conference paper 2017
- document
-
Dulin, D. (author), Arnold, Jamie J. (author), van Laar, T. (author), Oh, Hyung Suk (author), Lee, Cheri (author), Perkins, Angela L. (author), Harki, Daniel A. (author), Depken, S.M. (author), Cameron, Craig E. (author), Dekker, N.H. (author)RNA viruses pose a threat to public health that is exacerbated by the dearth of antiviral therapeutics. The RNA-dependent RNA polymerase (RdRp) holds promise as a broad-spectrum, therapeutic target because of the conserved nature of the nucleotide-substrate-binding and catalytic sites. Conventional, quantitative, kinetic analysis of antiviral...journal article 2017
- document
-
Son, Eun Jin (author), Lee, Sahng Ha (author), Kuk, Su Keun (author), Pesic, M. (author), Choi, Da Som (author), Ko, Jong Wan (author), Kim, Kayoung (author), Hollmann, F. (author), Park, Chan Beum (author)In green plants, solar-powered electrons are transferred through sophistically arranged photosystems and are subsequently channelled into the Calvin cycle to generate chemical energy. Inspired by the natural photosynthetic scheme, a photoelectrochemical cell (PEC) is constructed configured with protonated graphitic carbon nitride (p-g-C<sub>3...journal article 2017
- document
-
Cofactor-Free, Direct Photoactivation of Enoate Reductases for the Asymmetric Reduction of C=C BondsLee, Sahng Ha (author), Choi, Da Som (author), Pesic, M. (author), Lee, Yang Woo (author), Paul, C.E. (author), Hollmann, F. (author), Park, Chan Beum (author)Enoate reductases from the family of old yellow enzymes (OYEs) can catalyze stereoselective trans-hydrogenation of activated C=C bonds. Their application is limited by the necessity for a continuous supply of redox equivalents such as nicotinamide cofactors [NAD(P)H]. Visible light-driven activation of OYEs through NAD(P)H-free, direct...journal article 2017
- document
-
Lee, S. (author)This paper focuses on the conception and design of architecture as the work of producing media about buildings and other environmental artifacts. I approach<br/>the questions regarding simplicity and complexity through "interdependence" and "intermodality." I believe the two concepts offer more precise frames of relations and contexts involving...conference paper 2016
- document
-
Lee, S. (author)A work of architecture occupies a delicate position between functional performance and production of certain meaning and experience. The design of architecture becomes stifling when an architects attempts to harmonize the two facets. Modernist architects argued that a building should express materiality and assemblage in the most direct, “honest...poster 2016
- document
-
Alonso Del Pino, M. (author), Reck, Theodore (author), Lee, Choonsup (author), Jung-Kubiak, Cecile (author), Llombart, Nuria (author), Mehdi, Imran (author), Chattopadhyay, Goutam (author)This article presents the latest developments of our work related to a micro-lens antenna integrated in a heterodyne receiver using silicon micromachining technology at Terahertz frequencies. The antenna is composed of a waveguide feed which uses a leaky wave cavity to enhance the directivity and illuminate a shallow lens efficiently. The...conference paper 2016
- document
-
Yin, L.J. (author), Ji, Wei Wei (author), Liu, Shi Yu (author), He, Wei Dong (author), Zhao, Lin (author), Xu, Xin (author), Fabre, A. (author), Dierre, B.F.P.R. (author), Lee, Ming Hsien (author), van Ommen, J.R. (author), Hintzen, H.T.J.M. (author)Synthesizing pure phase Ba<sub>3</sub>Si<sub>6</sub>O<sub>9</sub>N<sub>4</sub> by the conventional solid-state reaction method is challenging because of easily formed secondary phase Ba<sub>3</sub>Si<sub>6</sub>O<sub>12</sub>N<sub>2</sub> showing similar crystal structure. In this work, an alternative low temperature synthesis method is...journal article 2016
- document
-
Sloof, W.G. (author), Pei, R. (author), McDonald, S.A. (author), Fife, J.L. (author), Shen, L. (author), Boatemaa, L. (author), Farle, A.S. (author), Yan, K. (author), Zhang, X. (author), Van der Zwaag, S. (author), Lee, P.D. (author), Withers, P.J. (author)MAX phase materials are emerging as attractive engineering materials in applications where the material is exposed to severe thermal and mechanical conditions in an oxidative environment. The Ti2AlC MAX phase possesses attractive thermomechanical properties even beyond a temperature of 1000 K. An attractive feature of this material is its...journal article 2016
- document
- Fang, Ming-Chung (author), Lee, Zi-Yi (author) journal article 2016
- document
- Park, Dong-Min. (author), Kim, Yonghwan (author), Seo, Min-Guk (author), Lee, Jaehoon (author) journal article 2016
- document
-
Holzheu, Stefanie (author), Lee, S. (author)With the work-in-progress research project ColorTracker we explore color as a formal design tool. This project-based paper describes a novel software application that processes color composition of a place and transcribes the data into three-dimensional geometries for architectural design. The research comprises two parallel trajectories: a...conference paper 2016
- document
-
Matthes, S (author), Grewe, V. (author), Lee, D (author), Linke, F. (author), Shine, Keith (author), Stromatas, Stavros (author)Trajectory optimisation is one option to reduce air traffic impact on environment. A multidimensional environmental assessment framework is needed to optimize impact on climate, local air quality and noise simultaneously. An interface between flight planning and environmental impact information can be established with environmental cost...conference paper 2016