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Kim, Jinhyun (author), Lee, S.H. (author), Tieves, F. (author), Choi, Da Som (author), Hollmann, F. (author), Paul, C.E. (author), Park, Chan Beum (author)Light-driven activation of redox enzymes is an emerging route for sustainable chemical synthesis. Among redox enzymes, the family of Old Yellow Enzyme (OYE) dependent on the nicotinamide adenine dinucleotide cofactor (NADH) catalyzes the stereoselective reduction of α,β-unsaturated hydrocarbons. Here, we report OYE-catalyzed asymmetric...journal article 2018
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Lee, W. (author), Yang, Xiaopeng (author), Jung, Daehen (author), Park, Seikwon (author), Kim, Heeeun (author), You, Heecheon (author)A revised pilot oxygen mask design was developed for better fit to the Korean Air Force pilots’ faces. The present study compared an existing pilot oxygen mask and a prototype of the revised mask design with 88 Korean Air Force pilots in terms of subjective discomfort, facial contact pressure, and slip distance on the face in high gravity....journal article 2018
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Ganji, M. (author), Shaltiel, Indra A. (author), Bisht, Shveta (author), Kim, E. (author), Kalichava, A. (author), Haering, Christian H. (author), Dekker, C. (author)It has been hypothesized that SMC protein complexes such as condensin and cohesin spatially organize chromosomes by extruding DNA into large loops. We directly visualized the formation and processive extension of DNA loops by yeast condensin in real time. Our findings constitute unambiguous evidence for loop extrusion. We observed that a...journal article 2018
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Kim, S.H. (author), Ganji, M. (author), Kim, E. (author), van der Torre, J. (author), Abbondanzieri, E. (author), Dekker, C. (author)The three-dimensional organization of DNA is increasingly understood to play a decisive role in vital cellular processes. Many studies focus on the role of DNA-packaging proteins, crowding, and confinement in arranging chromatin, but structural information might also be directly encoded in bare DNA itself. Here, we visualize plectonemes ...journal article 2018
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Lee, S. (author), Kim, Younguk (author), Eisemann, E. (author)This article presents an iterative backward-warping technique and its applications. It predictively synthesizes depth buffers for novel views. Our solution is based on a fixed-point iteration that converges quickly in practice. Unlike the previous techniques, our solution is a pure backward warping without using bidirectional sources. To...journal article 2018
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Stelloo, Suzan (author), Nevedomskaya, Ekaterina (author), Kim, Yongsoo (author), Schuurman, Karianne (author), Valle-Encinas, Eider (author), Lobo, João (author), Krijgsman, Oscar (author), Peeper, Daniel Simon (author), Chang, Seiwon Laura (author), Wessels, L.F.A. (author)The Androgen Receptor (AR) is the key-driving transcription factor in prostate cancer, tightly controlled by epigenetic regulation. To date, most epigenetic profiling has been performed in cell lines or limited tissue samples. Here, to comprehensively study the epigenetic landscape, we perform RNA-seq with ChIP-seq for AR and histone...journal article 2018
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Mustaffa, Z. (author), van Gelder, P.H.A.J.M. (author), Dawotola, A. W. (author), Yu, S. Y. (author), Kim, D. K. (author)This paper presents a method for assessing the reliability of a corroded pipeline placed in series, with special consideration given to the effect of the length scale imposed by each segment of the pipe. The features of corrosion in different pipe segments are statistically correlated; thus, a failure in one section may impact the adjacent...journal article 2018
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Kim, Jaehun (author), Won, Minz (author), Liem, C.C.S. (author), Hanjalic, A. (author)In this paper, we propose a hybrid Neural Collaborative Filtering (NCF) model trained with a multi-objective function to achieve a music playlist generation system. The proposed approach focuses particularly on the cold-start problem (playlists with no seed tracks) and uses a text encoder employing a Recurrent Neural Network (RNN) to exploit...conference paper 2018
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Choi, Woojun (author), Lee, Yongtae (author), Kim, Seonhong (author), Lee, Sanghoon (author), Jang, Jieun (author), Chun, Junhyun (author), Makinwa, K.A.A. (author), Chae, Youngcheol (author)This paper presents a compact resistor-based CMOS temperature sensor intended for dense thermal monitoring. It is based on an RC poly-phase filter (PPF), whose temperature-dependent phase shift is read out by a frequency-locked loop (FLL). The PPF's phase shift is determined by a zero-crossing (ZC) detector, allowing the rest of the FLL to be...journal article 2018
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Yang, Yujia (author), Kim, Chung Soo (author), Hobbs, Richard G. (author), Kruit, P. (author), Berggren, Karl K. (author)Semitransparent mirrors are standard elements in light optics for splitting light beams or creating two versions of the same image. Such mirrors do not exist in electron optics, although they could be beneficial in existing techniques such as electron interferometry and holography and could enable alternative electron imaging and spectroscopy...journal article 2018
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Choi, Woojun (author), Lee, Yong-Tae (author), Kim, Seonhong (author), Lee, Sanghoon (author), Jang, Jieun (author), Chun, Junhyun (author), Makinwa, K.A.A. (author), Chae, Youngcheol (author)In microprocessors and DRAMs, on-chip temperature sensors are essential components, ensuring reliability by monitoring thermal gradients and hot spots. Such sensors must be as small as possible, since multiple sensors are required for dense thermal monitoring. However, conventional BJT-based temperature sensors are not compatible with the sub...conference paper 2018
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Höfler, G.T. (author), Fernandez Fueyo, E. (author), Pesic, M. (author), Younes, S.H.H. (author), Choi, Eun Gyu (author), Kim, Yong H. (author), Urlacher, Vlada B. (author), Arends, I.W.C.E. (author), Hollmann, F. (author)A photoenzymatic NADH regeneration system was established. The combination of deazariboflavin as a photocatalyst with putidaredoxin reductase enabled the selective reduction of NAD<sup>+</sup> into the enzyme-active 1,4-NADH to promote an alcohol dehydrogenase catalysed stereospecific reduction reaction. The catalytic turnover of all the...journal article 2018
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Severson, Tesa M. (author), Kim, Yongsoo (author), Joosten, Stacey E.P. (author), Schuurman, Karianne (author), Van Der Groep, Petra (author), Moelans, Cathy B. (author), Ter Hoeve, Natalie D. (author), Manson, Quirine F. (author), Martens, J.W.M. (author), Wessels, L.F.A. (author)Male breast cancer (MBC) is rare and largely hormonally driven. Here, the authors examine the action of steroid hormone receptors in male and female breast cancers and find gender selective hormone receptor action that associates with the survival of MBC patients.journal article 2018
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Agarwal, Girish (author), Allen, Roland E. (author), Bezděková, Iva (author), Boyd, Robert W. (author), Chen, Goong (author), Hanson, R. (author), Hawthorne, Dean L. (author), Hemmer, Philip (author), Kim, Moochan B. (author), Kocharovskaya, Olga (author), Lee, D. (author), Lidström, Sebastian K. (author), Lidström, Suzy (author), Losert, Harald (author), Maier, Helmut (author), Neuberger, John W. (author), Padgett, Miles J. (author), Raizen, Mark (author), Rajendran, Surjeet (author), Rasel, Ernst (author), Schleich, Wolfgang P. (author), Scully, Marlan O. (author), Shchedrin, Gavriil (author), Shvets, Gennady (author), Sokolov, Alexei (author), Svidzinsky, Anatoly (author), Walsworth, Ronald L. (author), Weiss, Rainer (author), Wilczek, Frank (author), Willner, Alan E. (author), Yablonovich, Eli (author), Zheludev, Nikolay (author)The Winter Colloquium on the Physics of Quantum Electronics (PQE) has been a seminal force in quantum optics and related areas since 1971. It is rather mind-boggling to recognize how the concepts presented at these conferences have transformed scientific understanding and human society. In January 2017, the participants of PQE were asked to...journal article 2018
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Kim, A. (author), van der Bijl-Brouwer, M. (author)Design is today suggested as an alternative way of working in government contexts. Manydeveloped nations are trying to embed design in their public organizations. Yet recent<br/>studies have shown that design is not easily permeating into everyday practice of public organizations. This research therefore aims to understand what the current...conference paper 2019
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Kim, Jaehun (author), Picek, S. (author), Heuser, Annelie (author), Bhasin, Shivam (author), Hanjalic, A. (author)Profiled side-channel analysis based on deep learning, and more precisely Convolutional Neural Networks, is a paradigm showing significant potential. The results, although scarce for now, suggest that such techniques are even able to break cryptographic implementations protected with countermeasures. In this paper, we start by proposing a new...journal article 2019
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Lee, Yongtae (author), Choi, Woojun (author), Kim, Taewoong (author), Song, Seungwoo (author), Makinwa, K.A.A. (author), Chae, Youngcheol (author)This letter describes a compact resistor-based temperature sensor intended for the thermal monitoring of microprocessors and DRAMs. It consists of an RC poly phase filter (PPF) that is read out by a frequency-locked loop (FLL) based on a dual zero-crossing (ZC) detection scheme. The sensor,fabricated in 65-nm CMOS,occupies 5800 μm<sup>2</sup>...conference paper 2019
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Singh, Abhishek A. (author), Schuurman, Karianne (author), Nevedomskaya, Ekaterina (author), Stelloo, Suzan (author), Linder, Simon (author), Droog, Marjolein (author), Kim, Yongsoo (author), Sanders, Joyce (author), van der Poel, Henk (author), Bergman, Andries M. (author), Wessels, L.F.A. (author), Zwart, Wilbert (author)Chromatin immunoprecipitation (ChIP)-seq analyses of transcription factors in clinical specimens are challenging due to the technical limitations and low quantities of starting material, often resulting in low enrichments and poor signal-to-noise ratio. Here, we present an optimized protocol for transcription factor ChIP-seq analyses in human...journal article 2019
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Duives, D.C. (author), Wang, Guangxing (author), Kim, Jiwon (author)Currently, effective crowd management based on the information provided by crowd monitoring systems is difficult as this information comes in at the moment adverse crowd movements are already occurring. Up to this moment, very little forecasting techniques have been developed that predict crowd flows a longer time period ahead. Moreover, most...journal article 2019
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Lee, Yongtae (author), Choi, Woojun (author), Kim, Taewoong (author), Song, Seungwoo (author), Makinwa, K.A.A. (author), Chae, Youngcheol (author)This letter describes a compact resistor-based temperature sensor intended for the thermal monitoring of microprocessors and DRAMs. It consists of an RC poly phase filter (PPF) that is read out by a frequency-locked loop (FLL) based on a dual zero-crossing (ZC) detection scheme. The sensor, fabricated in 65-nm CMOS, occupies 5800 μ m2 and...journal article 2019