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De Jong, J. (author)
DNA is packaged together with proteins, such as histones, in the nucleus of a cell to form a fiber called chromatin. The nature of this packaging, the "chromatin structure", is essential for proper cell functioning. This is illustrated by the fact that perturbating chromatin can be associated with many diseases. Hence, artificial perturbation of...
doctoral thesis 2015
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Babaei, S. (author), Akhtar, W. (author), De Jong, J. (author), Reinders, M.J.T. (author), De Ridder, J. (author)
Genomically distal mutations can contribute to the deregulation of cancer genes by engaging in chromatin interactions. To study this, we overlay viral cancer-causing insertions obtained in a murine retroviral insertional mutagenesis screen with genome-wide chromatin conformation capture data. Here we find that insertions tend to cluster in 3D...
journal article 2015
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De Jong, S.A.P. (author), Slingerland, J.D. (author), Van de Giesen, N.C. (author)
This paper describes a method to correct for the effect of solar radiation in atmospheric distributed temperature sensing (DTS) applications. By using two cables with different diameters, one can determine what temperature a zero diameter cable would have. Such a virtual cable would not be affected by solar heating and would take on the...
journal article 2015
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Camfferman, F.A. (author), Ecury-Goossen, G.M. (author), La Roche, J.E. (author), De Jong, N. (author), Van 't Leven, W. (author), Vos, H.J. (author), Verweij, M.D. (author), Nasserinejad, K. (author), Cools, F. (author), Govaert, P. (author), Dudink, J. (author)
Introduction: Preterm infants are born during critical stages of brain development, in which the adaptive capacity of the fetus to extra-uterine environment is limited. Inadequate brain perfusion has been directly linked to preterm brain damage. Advanced high-frequency ultrasound probes and processing algorithms allow visualization of...
journal article 2015
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Hongsiri, W. (author), Danon, B. (author), De Jong, W. (author)
It is known that both acids and salts have a positive catalytic effect on the dehydration of pentoses to form furfural, a potentially attractive platform chemical. In this study the effects of the combined usage of an organic acid, instead of stronger mineral acids, and a saline catalyst is investigated. In order to assess these effects, the...
journal article 2014
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Kruizinga, P. (author), Springeling, G. (author), Van Soest, G. (author), Van der Steen, A.F.W. (author), De Jong, N. (author), Robertus, J.L. (author), Van der Lugt, A. (author)
We introduce a method for photoacoustic imaging of the carotid artery, tailored toward detection of lipid-rich atherosclerotic lesions. A common human carotid artery was obtained at autopsy, embedded in a neck mimicking phantom and imaged with a multimodality imaging system using interstitial illumination. Light was delivered through a 1.25-mm...
journal article 2014
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Van der Velden, W.C.P. (author), Van Zuijlen, A.H. (author), De Jong, A.T. (author), Bijl, H. (author)
A Large Eddy Simulation (LES) with four different closure models are analyzed in OpenFOAM, an open source Computional Fluid Dynamics (CFD) package and validated for the determination of the streamwise and spanwise coherence length of the pressure field below a turbulent boundary layer at low Reynolds numbers. Matching results are found for outer...
conference paper 2014
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Auping, W.L. (author), De Jong, S. (author), Pruyt, E. (author), Kwakkel, J.H. (author)
The US’ shale gas revolution, a spectacular increase in natural gas extraction from previously unconventional sources, has led to considerable lower gas prices in North America. This study focusses on consequences of the shale gas revolution on state stability of traditional oil and gas exporting countries in the vicinity of the EU. For this...
conference paper 2014
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Christodoulou, C. (author), Tsekos, C. (author), Tsalidis, G.A. (author), Fantini, M. (author), Panopoulos, K.D. (author), De Jong, W. (author), Kakaras, E. (author)
Few tests have been carried out in order to evaluate the use of cardoon in gasification and combustion applications most of the researchers dealt with agglomeration problems. The aim of this work is to deal with the agglomeration problem and to present a solution for the utilization of this biofuel at a near industrial application scale. For...
journal article 2014
document
De Jong, S.A.P. (author), Slingerland, J.D. (author), Van de Giesen, N.C. (author)
This paper describes a method to correct for the effect of solar radiation in atmospheric Distributed Temperature Sensing (DTS) applications. By using two cables with different diameters, one can determine what temperature a zero diameter cable would have. Such virtual cable would not be affected by solar heating and would take on the...
journal article 2014
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Van Ledden, M. (author), Van den Berg, N.J.F. (author), De Jong, M.S. (author), Van Gelder, P.H.A.J.M. (author), Den Heijer, C. (author), Vrijling, J.K. (author), Jonkman, S.N. (author), Roos, P.C. (author), Hulscher, S.J.M.H. (author), Lansen, A.J. (author)
This paper explores an alternative method to determine extreme surge levels at the Dutch Coast. For this exploration, specific focus is on the extreme water level at Hoek van Holland, The Netherlands. The alternative method has been based on a joint probability model of the storm characteristics at the North Sea. The intent of this method is to...
conference paper 2014
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Lu, Y. (author), Sutanudjaja, E. (author), Drost, N. (author), Hut, R.W. (author), Dunne, S.C. (author), Van de Giesen, N.C. (author), De Jong, K. (author), Van Beek, L. (author), Bierkens, M. (author)
journal article 2014
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Hut, R.W. (author), De Jong, S. (author), Van de Giesen, N.C. (author)
journal article 2014
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De Jong, J. (author), Akhtar, W. (author), Badhai, J. (author), Rust, A.G. (author), Rad, R. (author), Hilkens, J. (author), Berns, A. (author), Van Lohuizen, M. (author), Wessels, L.F.A. (author), De Ridder, J. (author)
The ability of retroviruses and transposons to insert their genetic material into host DNA makes them widely used tools in molecular biology, cancer research and gene therapy. However, these systems have biases that may strongly affect research outcomes. To address this issue, we generated very large datasets consisting of to unselected...
journal article 2014
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Siebelt, M. (author), Groen, H.C. (author), Koelewijn, S.J. (author), De Blois, E. (author), Sandker, M. (author), Waarsing, J.H. (author), Müller, C. (author), Van Osch, G.J.V.M. (author), De Jong, M. (author), Weinans, H.H. (author)
Introduction Articular cartilage needs sulfated-glycosaminoglycans (sGAGs) to withstand high pressures while mechanically loaded. Chondrocyte sGAG synthesis is regulated by exposure to compressive forces. Moderate physical exercise is known to improve cartilage sGAG content and might protect against osteoarthritis (OA). This study investigated...
journal article 2014
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Yakaboylu, O. (author), Harinck, J. (author), Smit, K.G. (author), De Jong, W. (author)
The supercritical water gasification process is an alternative to both conventional gasification as well as anaerobic digestion as it does not require drying and the process takes place at much shorter residence times; a few minutes at most. The drastic changes in the thermo-physical properties of water from the liquid state to the supercritical...
journal article 2014
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De Jong, P.M.A. (author)
During today’s aircraft descents, Air Traf?c Control (ATC) commands aircraft to descend to specific altitudes and directions to maintain separation and spacing from other aircraft. When the aircraft is instructed to maintain an intermediate descent altitude, it requires engine thrust to maintain speed, leading to increased fuel burn and noise...
doctoral thesis 2014
document
Knoop, V.L. (author), De Jong, D.M. (author), Hoogendoorn, S.P. (author)
It is analyzed what the effect is of the exact network structure on the shape of the Network Fundamental Diagram (NFD). In order to do so, a tool is developed which can create random networks for which the aggregated properties are the same. Using this tool, different urban networks with the same properties are designed. They show different NFDs...
conference paper 2014
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Knoop, V.L. (author), De Jong, D.M. (author), Hoogendoorn, S.P. (author)
The Macroscopic or Network Fundamental Diagram (NFD) describes the relationship between the network flow and the number of travellers within the network. The shape of the NFD is important for control purposes like perimeter control or routing. However, it is unknown how the network structure influences the shape of the NFD. This is studied in...
conference paper 2014
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Hut, R.W. (author), De Jong, S. (author), Van de Giesen, N.C. (author)
Abstract.
journal article 2013
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