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Lattwein, K.R. (author), Beekers, Inés (author), Kouijzer, Joop J.P. (author), Leon-Grooters, Mariël (author), Langeveld, Simone A.G. (author), van Rooij, Tom (author), van der Steen, A.F.W. (author), de Jong, N. (author), van Wamel, Willem J.B. (author), Kooiman, Klazina (author)Bacteria encased in a biofilm poses significant challenges to successful treatment, since both the immune system and antibiotics are ineffective. Sonobactericide, which uses ultrasound and microbubbles, is a potential new strategy for increasing antimicrobial effectiveness or directly killing bacteria. Several studies suggest that...journal article 2022
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Internalization of targeted microbubbles by endothelial cells and drug delivery by pores and tunnelsBeekers, Inés (author), Langeveld, Simone A.G. (author), Meijlink, Bram (author), van der Steen, A.F.W. (author), de Jong, N. (author), Verweij, M.D. (author), Kooiman, Klazina (author)Ultrasound insonification of microbubbles can locally enhance drug delivery by increasing the cell membrane permeability. To aid development of a safe and effective therapeutic microbubble, more insight into the microbubble-cell interaction is needed. In this in vitro study we aimed to investigate the initial 3D morphology of the endothelial...journal article 2022
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Panasiuk, Oleksandr (author), Hedström, Annelie (author), Langeveld, J.G. (author), Viklander, Maria (author)Infiltration and inflow (I/I) into sanitary sewers causes numerous negative effects on the whole wastewater management system and ultimately, on the receiving waters. Consequently, a number of methods have been developed to analyse the performance of sewer systems with respect to I/I, including: distributed temperature sensing (DTS), closed...journal article 2022
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Kraaikamp, C. (author), Langeveld, Niels (author)In this paper we consider continued fraction (CF) expansions on intervals different from [0,1]. For every x in such interval we find a CF expansion with a finite number of possible digits. Using the natural extension, the density of the invariant measure is obtained in a number of examples. In case this method does not work, a Gauss–Kuzmin...journal article 2017
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van Beek, Janko (author), Teesing, Gwen (author), Oude Munnink, Bas B. (author), Meima, Abraham (author), Vriend, Henrike J. (author), Elzakkers, Jessica (author), de Graaf, Miranda (author), Langeveld, J.G. (author), Medema, G.J. (author)An outbreak of SARS-CoV-2 Alpha variant (Pango lineage B.1.1.7) was detected at a primary school (School X) in Lansingerland, the Netherlands, in December 2020. The outbreak was studied retrospectively, and population-based screening was used to assess the extent of virus circulation and decelerate transmission. Cases were SARS-CoV-2...journal article 2022
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van Bijnen, J.A.C. (author), Korving, J.L. (author), Langeveld, J.G. (author), Clemens, F.H.L.R. (author)Due to a variety of contaminants in floodwater, exposure to urban pluvial flooding may pose a health risk to humans. In-sewer defects may cause increased pluvial flooding, possibly increasing health risks. This paper addresses the impact of in-sewer defects on urban pluvial flooding and, subsequently, on infection probabilities for humans. As...journal article 2018
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Meijer, D.H. (author), van Bijnen, J.A.C. (author), Langeveld, J.G. (author), Korving, J.L. (author), Post, J.A.B. (author), Clemens, F.H.L.R. (author)Underground water infrastructure is essential for life in cities. The aging of these infrastructures requires maintenance strategies to maintain a minimum service level. Not all elements are equally important for the functioning of the infrastructure as a whole. Identifying the most critical elements in a network is crucial for formulating...journal article 2018
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Nieuwenhuis, E.M. (author), Post, J.A.B. (author), Duinmeijer, S.P.A. (author), Langeveld, J.G. (author), Clemens, F.H.L.R. (author)The accumulation of FOG (Fat, Oil and Grease) deposits in sewer pumping stations results in an increase in maintenance costs, malfunctioning of pumps and, a potential increase of wastewater spills in receiving open water bodies. It is thought that a variety of parameters (e.g. geometry of the pump sump, pump operation, socioeconomic...journal article 2018
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Moreno Rodenas, A. (author), Cecinati, Francesca (author), Langeveld, J.G. (author), Clemens, F.H.L.R. (author)Integrated Catchment Modelling aims to simulate jointly urban drainage systems, wastewater treatment plant and rivers. The effect of rainfall input uncertainties in the modelling of individual urban drainage systems has been discussed in several studies already. However, this influence changes when simultaneously simulating several urban...journal article 2017
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van Daal-Rombouts, P.M.M. (author), Sun, Siao (author), Langeveld, J.G. (author), Bertrand-Krajewski, J.-L. (author), Clemens, F.H.L.R. (author)Optimisation or real time control (RTC) studies in wastewater systems increasingly require rapid simulations of sewer systems in extensive catchments. To reduce the simulation time calibrated simplified models are applied, with the performance generally based on the goodness of fit of the calibration. In this research the performance of three...journal article 2016
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Moreno Rodenas, A. (author), Bellos, V. (author), Langeveld, J.G. (author), Clemens, F.H.L.R. (author)This work presents a method to emulate the flow dynamics of physically based hydrodynamic simulators under variations of time-dependent rainfall and parametric scenarios. Although surrogate modelling is often employed to deal with the computational burden of this type of simulators, common techniques used for model emulation as polynomial...journal article 2018
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Meijer, D.H. (author), Post, Johan (author), van der Hoek, J.P. (author), Korving, Hans (author), Langeveld, J.G. (author), Clemens, F.H.L.R. (author)Drinking water distribution networks (WDNs) are a crucial infrastructure for life in cities. Deterioration of this ageing, and partly hidden from view, infrastructure can result in losses due to leakage and an increased contamination risk. To counteract this, maintenance strategies are required to maintain the service level. Information on...journal article 2021
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Makris, K. (author), Langeveld, J.G. (author), Clemens, F.H.L.R. (author)Polyvinyl chloride (PVC) has become one of the dominant construction materials for sewer systems over the past decades, as a result of its reputed merits. However, since PVC sewer pipes have operated for decades in a hostile environment, concern over their longevity has been lately raised by sewer managers in the Netherlands. Towards that...journal article 2019
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Panasiuk, Oleksandr (author), Hedström, Annelie (author), Langeveld, J.G. (author), de Haan, Cornelis (author), Liefting, Erik (author), Schilperoort, Remy (author), Viklander, Maria (author)Infiltration and inflow (I/I) into sewers cause negative effects on the sewer system, wastewater treatment plant and environment. Identifying the causes and locating the inflows is necessary in order to address the I/I problem. This paper focuses on using distributed temperature sensing (DTS) for identifying, locating and characterising I/I...journal article 2019
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Rietveld, M.W.J. (author), Clemens, F.H.L.R. (author), Langeveld, J.G. (author)Gully pots are utilized for conveying runoff to drainage systems, as well as for reducing the system’s solids loading by retaining suspended solids. However, the accumulation of solids in gully pots reduces their removal efficiency, leading to an increase in solids transport towards the drainage system. This article aims to identify the main...journal article 2020
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Rietveld, M.W.J. (author), Clemens, F.H.L.R. (author), Langeveld, J.G. (author)Runoff entering urban drainage systems contains suspended solids, which carry pollutants and may cause blockages in downstream parts of the system (for example infiltration facilities). Suspended solids inflow should, therefore, preferably be controlled by solids removal at gully pots. This paper presents the results of lab experiments on the...journal article 2020
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Izquierdo-Lara, Ray W. (author), Heijnen, Leo (author), Oude Munnink, Bas B. (author), Schapendonk, Claudia M.E. (author), Elsinga, Goffe (author), Langeveld, J.G. (author), Post, Johan (author), Prasad, Divyae K. (author), Medema, G.J. (author)Monitoring of SARS-CoV-2 in wastewater (WW) is a promising tool for epidemiological surveillance, correlating not only viral RNA levels with the infection dynamics within the population, but also to viral diversity. However, the complex mixture of viral lineages in WW samples makes tracking of specific variants or lineages circulating in the...journal article 2023
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Langeveld, J.G. (author), Cherqui, Frédéric (author), Tscheikner-Gratl, Franz (author), Muthanna, Tone Merete (author), Juarez, Marina Fernandez Delgado (author), Leitão, Joao P. (author), Roghani, Bardia (author), Kerres, Karsten (author), do Céu Almeida, Maria (author)Urban drainage systems have developed way beyond the traditional piped combined or separate sewer systems. Many ‘new’ systems are being introduced, ranging from stormwater infiltration facilities to green roofs. However, the widely advocated blue-green infrastructures are typically overlooked by asset managers, which will very likely have...journal article 2022
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Cecinati, Francesca (author), Moreno Rodenas, A. (author), Rico-Ramirez, Miguel A. (author), ten Veldhuis, Marie-claire (author), Langeveld, J.G. (author)In urban hydrological models, rainfall is the main input and one of the main sources of uncertainty. To reach sufficient spatial coverage and resolution, the integration of several rainfall data sources, including rain gauges and weather radars, is often necessary. The uncertainty associated with rain gauge measurements is dependent on...journal article 2018
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Moreno Rodenas, A. (author), Tscheikner-Gratl, F. (author), Langeveld, J.G. (author), Clemens, F.H.L.R. (author)Receiving water quality simulation in highly urbanised areas requires the integration of several processes occurring at different space-time scales. These integrated catchment models deliver results with a significant uncertainty level associated. Still, uncertainty analysis is seldom applied in practice and the relative contribution of the...journal article 2019