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Strachinaru, Mihai (author), Bosch, Johan G. (author), van Dalen, Bas M. (author), van Gils, Lennart (author), van der Steen, A.F.W. (author), de Jong, N. (author), Geleijnse, Marcel L. (author), Vos, H.J. (author)
The propagation velocity of shear waves relates to tissue stiffness. We prove that a regular clinical cardiac ultrasound system can determine shear wave velocity with a conventional unmodified tissue Doppler imaging (TDI) application. The investigation was performed on five tissue phantoms with different stiffness using a research platform...
journal article 2017
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Kokhuis, Tom J A (author), Naaijkens, Benno A. (author), Juffermans, Lynda J.M. (author), Kamp, Otto (author), van der Steen, A.F.W. (author), Versluis, Michel (author), de Jong, N. (author)
The use of stem cells for regenerative tissue repair is promising but hampered by the low number of cells delivered to the site of injury. To increase the delivery, we propose a technique in which stem cells are linked to functionalized microbubbles, creating echogenic complex dubbed StemBells. StemBells are highly susceptible to acoustic...
journal article 2017
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van Rooij, Tom (author), Beekers, D.I. (author), Lattwein, Kirby R. (author), van der Steen, A.F.W. (author), de Jong, N. (author), Kooiman, Klazina (author)
One of the main challenges for ultrasound molecular imaging is acoustically distinguishing nonbound microbubbles from those bound to their molecular target. In this in vitro study, we compared two types of in-house produced targeted lipid-coated microbubbles, either consisting of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine, C16:0 (DPPC) or 1...
journal article 2017
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Cohen, M.A. (author), Yuan, M. (author), de Jong, B.W.A. (author), Beukers, Ewout (author), Bosman, S.J. (author), Steele, G.A. (author)
We report on a technique for applying a DC bias in a 3D microwave cavity. We achieve this by isolating the two halves of the cavity with a dielectric and directly using them as DC electrodes. As a proof of concept, we embed a variable capacitance diode in the cavity and tune the resonant frequency with a DC voltage, demonstrating the...
journal article 2017
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Chen, C. (author), Chen, Z. (author), Bera, Deep (author), Raghunathan, S.B. (author), Shabanimotlagh, M. (author), Noothout, E.C. (author), Chang, Z.Y. (author), Ponte, Jacco (author), Prins, Christian (author), Vos, H.J. (author), Bosch, J.G. (author), Verweij, M.D. (author), de Jong, N. (author), Pertijs, M.A.P. (author)
This paper presents a power-and area-efficient front-end application-specific integrated circuit (ASIC) that is directly integrated with an array of 32 × 32 piezoelectric transducer elements to enable next-generation miniature ultrasound probes for real-time 3-D transesophageal echocardiography. The 6.1 × 6.1 mm<sup>2</sup> ASIC, implemented...
journal article 2017
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Vos, H.J. (author), van Dalen, Bas M. (author), Heinonen, Ilkka (author), Bosch, Johan G. (author), Sorop, Oana (author), Duncker, Dirk J. (author), van der Steen, A.F.W. (author), de Jong, N. (author)
Cardiac muscle stiffness can potentially be estimated non-invasively with shear wave elastography. Shear waves are present on the septal wall after mitral and aortic valve closure, thus providing an opportunity to assess stiffness in early systole and early diastole. We report on the shear wave recordings of 22 minipigs with high-frame-rate...
journal article 2017
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Daeichin, Verya (author), van Rooij, Tom (author), Skachkov, Ilya (author), Ergin, Bulent (author), Specht, Patricia A.C. (author), Lima, Alexandre (author), Ince, Can (author), Bosch, Johan G. (author), van der Steen, A.F.W. (author), de Jong, N. (author), Kooiman, Klazina (author)
Although high-frequency ultrasound imaging is gaining attention in various applications, hardly any ultrasound contrast agents (UCAs) dedicated to such frequencies (&gt;15 MHz) are available for contrast-enhanced ultrasound (CEUS) imaging. Moreover, the composition of the limited commercially available UCAs for high-frequency CEUS (hfCEUS) is...
journal article 2017
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van de Berg, N.J.P. (author), de Jong, T.L. (author), van Gerwen, D.J. (author), Dankelman, J. (author), van den Dobbelsteen, J.J. (author)
Steering of needles involves the planning and timely modifying of instrument-tissue force interactions to allow for controlled deflections during the insertion in tissue. In this work, the effect of tip shape on these forces was studied using 10 mm diameter needle tips. Six different tips were selected, including beveled and conical versions,...
journal article 2017
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Kooiman, Klazina (author), van Rooij, Tom (author), Qin, Bin (author), Mastik, Frits (author), Vos, H.J. (author), Versluis, Michel (author), Klibanov, Alexander L. (author), de Jong, N. (author), Villanueva, Flordeliza S. (author), Chen, Xucai (author)
Acoustic behavior of lipid-coated microbubbles has been widely studied, which has led to several numerical microbubble dynamics models that incorporate lipid coating behavior, such as buckling and rupture. In this study we investigated the relationship between micro-bubble acoustic and lipid coating behavior on a nanosecond scale by using...
journal article 2017
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Di Marcello, M. (author), Tsalidis, G.A. (author), Spinelli, G. (author), de Jong, W. (author), Kiel, J.H.A. (author)
Torrefaction is a promising biomass upgrading technology as it makes biomass more coal alike and offers benefits in logistics and handling operations. Gasification is an attractive thermochemical conversion technology due to its flexibility in the product gas end-uses. Therefore, it is valuable to investigate whether additional benefits are...
journal article 2017
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Noorbergen, Lars J. (author), Abels, H.A. (author), Hilgen, Frederik J. (author), Robson, Brittany E. (author), de Jong, Edwin (author), Dekkers, Mark J. (author), Krijgsman, Wout (author), Smit, Jan (author), Collinson, Margaret E. (author), Kuiper, Klaudia F. (author)
Fluvial systems in which peat formation occurs are typified by autogenic processes such as river meandering, crevasse splaying and channel avulsion. Nevertheless, autogenic processes cannot satisfactorily explain the repetitive nature and lateral continuity of many coal seams (compacted peats). The fluvial lower Palaeocene Tullock Member of...
journal article 2017
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Lajoinie, Guillaume (author), Linnartz, Erik (author), Kruizinga, P. (author), de Jong, N. (author), Stride, Eleanor (author), Van Soest, Gijs (author), Versluis, Michel (author)
Microbubbles are used to enhance the contrast in ultrasound imaging. When coated with an optically absorbing material, these bubbles can also provide contrast in photoacoustic imaging. This multimodal aspect is of pronounced interest to the field of medical imaging. The aim of this paper is to provide a theoretical framework to describe the...
journal article 2017
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Lajoinie, Guillaume (author), Lee, Jeong Yu (author), Owen, Joshua (author), Kruizinga, P. (author), de Jong, N. (author), Van Soest, Gijs (author), Stride, Eleanor (author), Versluis, Michel (author)
Photoacoustic (PA) imaging offers several attractive features as a biomedical imaging modality, including excellent spatial resolution and functional information such as tissue oxygenation. A key limitation, however, is the contrast to noise ratio that can be obtained from tissue depths greater than 1-2 mm. Microbubbles coated with an...
journal article 2017
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Tsalidis, G.A. (author), Di Marcello, M. (author), Spinelli, G. (author), de Jong, W. (author), Kiel, J.H.A. (author)
Torrefaction is a promising biomass upgrading method, offering advantages in logistics and handling. Gasification is an attractive thermochemical conversion technology due to its flexibility in the product gas end-use. The aim of this paper is to investigate the impact of torrefaction on the gasification performance of a softwood (spruce) and...
journal article 2017
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Mulvana, Helen (author), Browning, Richard J. (author), Luan, Ying (author), de Jong, N. (author), Tang, Meng-Xing (author), Eckersley, Robert J. (author), Stride, Eleanor (author)
journal article 2017
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Tsalidis, G.A. (author), Discha, F.E. (author), Korevaar, G. (author), Haije, W.G. (author), de Jong, W. (author), Kiel, J.H.A. (author)
This study evaluates whether a transition of large ports facilities to biofuel production for mobility improves the environmental performance and satisfies the renewable energy directive (RED) and it is the first LCA study that considers biofuel production from torrefied wood. The systems studied are wood, torrefied wood, and straw pellets...
journal article 2017
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Mulder, Inge A. (author), Khmelinskii, Artem (author), Dzyubachyk, Oleh (author), de Jong, Sebastiaan (author), Rieff, Nathalie (author), Wermer, Marieke J.H. (author), Hoehn, Mathias (author), Lelieveldt, B.P.F. (author), van den Maagdenberg, Arn M.J.M. (author)
Magnetic resonance imaging (MRI) has become increasingly important in ischemic stroke experiments in mice, especially because it enables longitudinal studies. Still, quantitative analysis of MRI data remains challenging mainly because segmentation of mouse brain lesions in MRI data heavily relies on time-consuming manual tracing and...
journal article 2017
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Fernandez Lopez, M. (author), Anastasakis, K. (author), de Jong, W. (author), Valverde, Jose Luis (author), Sanchez-Silva, Luz (author)
Fast pyrolysis characterization of three dry manure samples was studied using a pyrolyzer. A heating rate of 600°C/s and a holding time of 10 s were selected to reproduce industrial conditions. The effect of the peak pyrolysis temperature (600, 800 and 1000°C) on the pyrolysis product yield and composition was evaluated. Char and bio-oil were...
conference paper 2017
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de Jong, T.L. (author), Pluymen, L.H. (author), van Gerwen, D.J. (author), Kleinrensink, GJ (author), Dankelman, J. (author), van den Dobbelsteen, J.J. (author)
Medical phantoms can be used to study needle-tissue interaction and to train medical residents. The purpose of this research is to study the suitability of polyvinyl alcohol (PVA) as a liver tissue mimicking material in terms of needle-tissue interaction. Insertions into ex-vivo human livers were used for reference. Six PVA samples were...
journal article 2017
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de Jong, P. (author), Kremer, F.G.J. (author)
conference paper 2017
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