"uuid","repository link","title","author","contributor","publication year","abstract","subject topic","language","publication type","publisher","isbn","issn","patent","patent status","bibliographic note","access restriction","embargo date","faculty","department","research group","programme","project","coordinates"
"uuid:e9127977-27f5-46d2-8f12-732a789ae796","http://resolver.tudelft.nl/uuid:e9127977-27f5-46d2-8f12-732a789ae796","Biomass gasification in a novel 50kWth indirectly heated bubbling fluidized bed steam reformer","Del Grosso, M. (TU Delft Large Scale Energy Storage); de Jong, W. (TU Delft Large Scale Energy Storage)","","2016","style=""margin: 0cm 0cm 10pt;"">In the global chase towards sustainability and cleaner ways of generating power, the utilization of biomass for clean energy conversion process has become increasingly interesting as biomass is potentially a CO2-neutral energy source. Among the processes known to produce power, gasification represents an attractive and versatile technology to convert wide variety of biomass into product gas mainly composed by CO, H2, CO2, H2O and CH4, that can be used for (combined) heat and power (CHP) production, transportation fuels and chemicals. For small to medium scale biomass gasification, fluidized bed technology is attractive: the process takes place in a bed of small particles fluidised by a suitable gasification medium and the very good gas-solid mixing ensures temperature uniformity through the bed and leads to an excellent mass and heat transfer. In indirectly heated gasification, also known as second generation or allothermal gasification, the heat needed for the desired reactions is provided by ex-situ oxidation reactions and this leads to a higher quality product.","","en","abstract","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:b3bb4606-d0f6-4db5-984b-2cbdb7ac6860","http://resolver.tudelft.nl/uuid:b3bb4606-d0f6-4db5-984b-2cbdb7ac6860","Biomass gasification in a novel 50kWth indirectly heated bubbling fluidized bed steam reformer: Radiant Tube Burner preliminary tests","Del Grosso, M. (TU Delft Large Scale Energy Storage); Tsekos, C. (TU Delft Large Scale Energy Storage); de Jong, W. (TU Delft Large Scale Energy Storage)","","2018","","","en","abstract","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:a7f0bb8c-492d-4c90-bad1-32b454f59a1e","http://resolver.tudelft.nl/uuid:a7f0bb8c-492d-4c90-bad1-32b454f59a1e","Real estate implications of transitions in Dutch health care institutions","Brand, Alexander (AAG); Bollinger, Daan (AAG); de Jong, P. (TU Delft Design & Construction Management); van der Voordt, Theo (TU Delft Real Estate Management)","","2017","Due to structural changes in laws and regulations and ways of financing, Dutch health care organisations are in a phase of reorientation and transition. As such, many strategical issues have to be solved that will influence their corporate real estate strategy. In such a dynamic context real estate represents a high risk. The transition requires increased transparency and understanding of performance. The current Dutch situation can be described as:
•Increased vacancy arouses. Hypothesis: Health care organisations prevent vacancy by disposing of or reinvestments in existing locations, with improved quality of the remaining real estate.
•Lower rates and increased uncertainty. Hypothesis: The response will consists of increased focus, demanding a proper preparation.
•A growing dilemma of lower budget for real estate and high need for investments. Hypothesis: The level of available financial resources for the renewal of the stock and guaranteed sound management is questionable.
The purpose of the research is to test these hypotheses in order to gain a better understanding of the qualitative and quantitative (financial) mutations in health care real estate and to bridge the gap between the current supply and the future demand.
To which extent are Dutch health care organisations ready to realise the transition by the introduction of new concepts, in order to meet the future demand of health care real estate?
Based on a survey, relevant real estate related data including performance parameters has been collected by AAG, a consultancy firm and shared service centre for health and care, in 2015 and 2016. This database is the starting point for benchmark analyses on the resilience and flexibility of health care organisations to provide the required transition.
The data include qualitative data about the location, building, and user experience, and quantitative information (financial, physical, features). Mapping the current situation (IST) generates a better understanding of the (im)possibilities of the health care real estate in the Netherlands (1). In order to forecast the effects of the transition it is necessary to use future scenarios (SOLL) to reveal resilience and flexibility (2). Such scenarios are qualitative as well as quantitative – determining the possible maximum investment and improvement (3). These scenarios will be hold against the actual plans of the health care organisation (4).
gaan om te zwaaien naar de buren met de illusie dat deze dit live kunnen zien op hun computer. Geo-informatie kan lang niet altijd zomaar gebruikt worden. Geo-informatie mag ook lang niet altijd zomaar gebruikt worden. Met dit laatste komen we bij het onderwerp van dit boek: het informatierecht. Openbaarheid, gebruiksvoorwaarden, intellectuele eigendom, en privacy zijn factoren waar op zijn minst rekening mee moet worden gehouden bij het gebruik van de geo-informatie.","Boekdeel nat.wet.","nl","book chapter","Reed Business Information","","","","","","","","","","OLD Geo-information and Land Development","","",""
"uuid:cd0c66f8-c461-4fee-b0ed-ce07ceee22ae","http://resolver.tudelft.nl/uuid:cd0c66f8-c461-4fee-b0ed-ce07ceee22ae","Types of study by design","van der Voordt, Theo (TU Delft Real Estate Management); de Jong, T.M. (TU Delft Technical Ecology and Methodology (OLD))","de Jong, T.M. (editor); van der Voordt, D.J.M. (editor)","2002","In this book study by design – also called research by or through design – is defined as the development of knowledge by designing, studying the effects of this design, changing the design itself or its context, and studying the effects of the transformations. The ‘TOTE-model’ from systems analysis may be recognised in this : Test → Operate → Test → Exit. Methodologically this should be preceded by a pre-design study, particularly in order to ascertain which requirements should be met by the design; although a design does not need to be goal-directed by definition.","","en","book chapter","DUP Science","","","","","","","","","","Real Estate Management","","",""
"uuid:0766f773-ffd4-4de3-9597-4b5634c08f72","http://resolver.tudelft.nl/uuid:0766f773-ffd4-4de3-9597-4b5634c08f72","Criteria for scientific study and design","de Jong, T.M. (TU Delft Technical Ecology and Methodology (OLD)); van der Voordt, Theo (TU Delft Real Estate Management)","de Jong, T.M. (editor); van der Voordt, D.J.M. (editor)","2002","Could a design be the product of scientific work to be compared with a scientific report? If so, under which conditions and when? The topic is eagerly discussed both within and outside of faculties of architecture. On the web-site of the Design Research Society (DRS) there is a lively debate on what a design study and a study by design really are and when a designer can also be designated a scientist. These questions stood central during the 1996 EAAE Congress organised by the Delft Faculty of Architecture on the theme ‘Doctorates in Design + Architecture’.a In order to answer these questions we discuss first the terms ‘research’ and ‘study’ and the usual pre-requisites that must be met for study to be designated ‘scientific’. Next, similarities and differences between designing and studying are dealt with. Following that, we discuss the usual way in the scientific community of looking at the criteria for a design to be branded as a product of scientific study. For that purpose a summary is given of the requirements the Technical University in Delft associates with a the rôle it played during the initiative leading to this handbook of design related study. Finally we give a specimen of criteria for evaluation of a scientific architectural design (ex post) and of a proposal for a design related study (ex ante).","","en","book chapter","DUP Science","","","","","","","","","","Technical Ecology and Methodology (OLD)","","",""
"uuid:175b1149-4c08-425c-a0ca-0bc74df3f6cd","http://resolver.tudelft.nl/uuid:175b1149-4c08-425c-a0ca-0bc74df3f6cd","Introduction","de Jong, T.M. (TU Delft Technical Ecology and Methodology (OLD)); van der Voordt, Theo (TU Delft Real Estate Management)","de Jong, T.M. (editor); van der Voordt, D.J.M. (editor)","2002","This methodological book describes eight forms of study as they relate to design:
- Naming and describing;
- Design research and typology;
- Evaluating;
- Modelling;
- Programming and optimising;
- Technical study;
- Design study;
- Study by design.
These eight sections are the spine of the work. Its compartmentalisation is based on the work of two Methodology Committees of the Faculty of Architecture at the Technical University of Delft (in 1990 and in 2000 AD) and establishes, in this sense, the list of the methodological end-terms of the education. The sequencing of the sections and the chapters within them is showing a certain space for conditioning. Design research, for instance, is impossible without a description of the designs to be studied; in its turn describing study pre-supposes that the components and concepts in these designs can be named and retrieved (naming).","","en","book chapter","DUP Science","","","","","","","","","","Technical Ecology and Methodology (OLD)","","",""
"uuid:751b2aeb-2be1-4b05-8f30-c09a298b9879","http://resolver.tudelft.nl/uuid:751b2aeb-2be1-4b05-8f30-c09a298b9879","Retrieval and reference","de Jong, T.M. (TU Delft Technical Ecology and Methodology (OLD)); van der Voordt, Theo (TU Delft Real Estate Management)","de Jong, T.M. (editor); van der Voordt, D.J.M. (editor)","2002","Knowledge from study may be transferred in different ways: in words and images, via lectures and exhibitions, in the form of articles or books; and electronically.
For the time being, the form used most frequently is written publication in text and illustration. However publishing on CD-ROM and the Internet are witnessing rapid development. Maybe this is going to have important consequences for the way in which people are searching for information. In this contribution we discuss some points needing attention for optimal accessibility of knowledge from study and suitably dealing with the sources used. We refer to handbooks for the conventional playing rules of reporting in writing such as clear and interest evoking titles of chapters and paragraphs, clear structure and table of contents, avoiding unnecessary jargon, a clear summary and their like.a,b The emphasis in this Chapter is on adequate pointers to references and the use of key-words.
Before embarking, first, something about the way to stimulate potential readers to take notice of the information. It starts already with the cover and the titlepage. These give a first impression of what is waiting for the potential reader. With this author, text or images present themselves. One glance should make clear what the subject is; although it is sometimes attractive to confuse the reader. Starting from cover and title page, the reference data (copyright notice, year of publication, ISBN number, place of issue and publisher), table of contents, foreword (written by a recommending outsider or referee) and introduction, the reader is introduced from his own world into the world of the author. The author and those responsible for the lay-out should picture themselves in this process and shape the publication from the vantage point of potential readers (the target audience), their questions, their pre-suppositions, or lack thereof.
Possible pre-suppositions of the reader should be supplemented or corrected. With this it is prevented that potential readers are thinking after a while “What the hell is this?” A clear text on the back cover, an index of key-words, a list of references and a sensible use of footnotes and final-notes are important conditions as well in order to achieve a publication that invites reading.","","en","book chapter","DUP Science","","","","","","","","","","Technical Ecology and Methodology (OLD)","","",""
"uuid:cd130ae4-def7-4c5f-8b11-8100a6f60011","http://resolver.tudelft.nl/uuid:cd130ae4-def7-4c5f-8b11-8100a6f60011","Analysis of ideas competition entries.","Volker, L. (TU Delft Design & Construction Management); Zijlstra, H. (TU Delft Old - Section Restoration, Re-use and Renovation); de Jong, P (External organisation); van Dorst, M.J. (TU Delft Environmental Technology and Design)","Smit, MGJ (editor)","2009","","Vakpubl., Overig wet. > 3 pag","en","book chapter","TU Delft, Faculty of Architecture","","","","","","","","","","Design & Construction Management","","",""
"uuid:ee1a4b6d-a7f9-4fb2-ac5c-8926d3a59c20","http://resolver.tudelft.nl/uuid:ee1a4b6d-a7f9-4fb2-ac5c-8926d3a59c20","Sorption enhanced catalysis for CO2 hydrogenation towards fuels and chemicals with focus on methanation","Wei, L. (TU Delft Large Scale Energy Storage); Haije, W.G. (TU Delft ChemE/Materials for Energy Conversion and Storage); Grénman, Henrik (Åbo Akademi University); de Jong, W. (TU Delft Large Scale Energy Storage)","Romolos Cesario, Moisés (editor); Araújo de Macedo, Daniel (editor)","2022","Hydrogen produced by the electrolysis of water using sustainable electricity will play an increasingly important role as an energy and a feedstock vector. Shifting from fossil to renewable resources means that new industrial platforms have to be set up to provide carbon-based fuels and bulk base chemicals to replace the current fossil resources based routes. The global demand cannot be met by indirect use of carbon dioxide via biomass necessitating the use from point sources or direct air capture, which changes the value of CO2 from waste to commodity chemicals. The production of chemicals by hydrogenation of CO2 is typically hampered by the thermodynamic conversion being far from 100% under currently viable reaction conditions. The equilibrium can, however, be shifted to increase conversion by removing one of the reaction products, namely water, from the reaction mixture with sorbents like zeolites. Prerequisite to conversion enhancement and process intensification is the close proximity of sorption and catalytic sites. This review presents the state of the art in synthesis and application of these, in fact, bifunctional materials.","Bifunctional materials; Large scale green base chemicals; Methane; Separation enhanced CO hydrogenation; Zeolite catalyst","en","book chapter","Elsevier","","","","","Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2022-10-29","","","Large Scale Energy Storage","","",""
"uuid:eef63f11-cfa0-409c-b3f6-0ec17e4118bd","http://resolver.tudelft.nl/uuid:eef63f11-cfa0-409c-b3f6-0ec17e4118bd","Methods on QRA","de Jong, J.H.","","2004","","offshore","","conference paper","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:2910f31a-d764-41f0-a46d-9f13657b2c9d","http://resolver.tudelft.nl/uuid:2910f31a-d764-41f0-a46d-9f13657b2c9d","Gradient estimation in uncertain data","de Jong, F.; Van Vliet, L.J.; Jonker, P.P.","","1998","","","en","conference paper","","","","","","","","","","","","","",""
"uuid:37b797cd-7796-4fa7-aa32-a018c5a9b10f","http://resolver.tudelft.nl/uuid:37b797cd-7796-4fa7-aa32-a018c5a9b10f","Validation of a time domain panel code for high speed craft operating in stern quartering seas","van Walree, Frans; de Jong, Pepijn","","2011","","resistance & propulsion","","conference paper","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:b79515ab-18c8-49fe-b471-2b16ac82259e","http://resolver.tudelft.nl/uuid:b79515ab-18c8-49fe-b471-2b16ac82259e","Deterministic validation of a time domain panel code for parametric roll","van Walree, Frans; de Jong, Pepijn","","2011","","resistance & propulsion","","conference paper","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:2f7e9a64-7ade-41cb-a80a-ca73b5991cb7","http://resolver.tudelft.nl/uuid:2f7e9a64-7ade-41cb-a80a-ca73b5991cb7","Towing point influence in model tests for high-speed vessels","de Jong, P.; Kremer, F.G.J.","","2017","","hydrodynamics","","conference paper","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:19f6855e-a4ac-4677-8fbc-a1b636aabcdf","http://resolver.tudelft.nl/uuid:19f6855e-a4ac-4677-8fbc-a1b636aabcdf","Hydrodynamic lift in a time-domain panel method for the seakeeping of fast ships","de Jong, Pepijn; van Walree, Frans","","2008","","hydrodynamics","","conference paper","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:4d0ee515-8f49-4386-9023-1062172b7f0c","http://resolver.tudelft.nl/uuid:4d0ee515-8f49-4386-9023-1062172b7f0c","The development and validation of a time-domain panel method for the seakeeping of high speed ships","de Jong, Pepijn; van Walree, Frans","","2009","","hydrodynamics","","conference paper","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:ccfb474e-d8f7-4f58-9157-91b5d6648ad0","http://resolver.tudelft.nl/uuid:ccfb474e-d8f7-4f58-9157-91b5d6648ad0","Experimental and numerical investigation on the heel and drift induced hydrodynamic loads of a high speed craft","Bonci, M.; de Jong, P.; van Walree, F.; Renilson, M.; Keuning, L.; Huijsmans, R.","","2017","","hydrodynamics","","conference paper","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:10234710-e061-4df7-a1ba-ba7b48908b9c","http://resolver.tudelft.nl/uuid:10234710-e061-4df7-a1ba-ba7b48908b9c","Time domain simulations of the behaviour of fast ships in oblique seas","van Walree, Frans; de Jong, Pepijn","","2008","","hydrodynamics","","conference paper","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:da9ba99f-c5fc-41b6-a5dc-9e911196b978","http://resolver.tudelft.nl/uuid:da9ba99f-c5fc-41b6-a5dc-9e911196b978","Design towards higher integration levels in power electronics","de Jong, E.C.W.; Popovic, J.; Ferreira, J.A.","","2006","","","en","conference paper","IEEE","","","","","","","","Electrical Engineering, Mathematics and Computer Science","","","","",""
"uuid:128d1f1d-8b4e-410d-a690-f752ca89f96d","http://resolver.tudelft.nl/uuid:128d1f1d-8b4e-410d-a690-f752ca89f96d","Evaluation of the Free Surface Evaluation in a Time-Domain Panel Method for the Seakeeping of high Speed Ships","de Jong, Pepijn; van Walree, Frans; Keuning, Lex; Huijsman, Rene H.M.","","2007","","offshore","","conference paper","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:d8e635d2-2ba1-47f1-8ad0-59d44c45024d","http://resolver.tudelft.nl/uuid:d8e635d2-2ba1-47f1-8ad0-59d44c45024d","Climate change and inland shipping","van der Toorn, A. (a.vandertoorn@tudelft.nl) (TU Delft, Civil Engineering and Geosciences, Hydraulic Engineering); de Jong, M. (m.dejong@tudelft.nl)) (TU Delft, Civil Engineering and Geosciences, Hydraulic Engineering)","","2010","Although much attention is given to the consequences of climate change with respect to melting icecaps, starving polar bears, sea level rise and inadequate storm defense systems, there may be severe consequences for inland shipping too. Not only because of more frequent occurrence and longer durations of closed storm surge barriers, which may disconnect the free entrance for inland vessels to seaports, but also because the hinterland connections itself may change in the sense that so called melting rivers with a rather stable and predictable discharge over the year, may change in fast fluctuating and more unpredictable so called rain rivers. This may sometimes lead to higher water levels, which may give problems for the passage of bridges by (to) high inland (container) vessels, but what is more undesired are (long) periods of low discharge, which may allow only shipping with restricted shallow draught, which in turn may cause disruption of lean and mean logistic chains. There are many different type of solutions to anticipate to this future threats, such as better river management (think about retention basins in times of high discharge or in times of low discharge think about inflow from reservoirs, flow reduction by weirs and adjustable groins, extra draught by dedicated dredging), other more shallow ship properties, extra and/or shifted fleet capacity, other transport modalities, more accurate, actual and long term predicted river depth information, logistic buffers, extra stock, etc. An extra complication comes from the fact that some of these measures should be taken in the public domain by (inter)national government(s), local authorities, river managers, etc., while others are more or less the responsibility of private transport companies, producers or even individual ship owners. And most of them are believers of the law of up scaling more than downsizing! In this paper some results of the working group Inland navigation from the project Knowledge for Climate are presented and a few specific measures such as infrastructural adaptations are further investigated and scored against different criteria.","climate change; inland navigation; Rhine river; adaptive measures","en","conference paper","","","","","","","","","","","","","",""
"uuid:a53a96d2-dd50-4b84-9680-7fc6edd97daa","http://resolver.tudelft.nl/uuid:a53a96d2-dd50-4b84-9680-7fc6edd97daa","Time domain simulations of the behaviour of fast ships in oblique seas","van Walree, Frans; de Jong, Pepijn","de Jong, P. (advisor)","2008","","hydrodynamics","","conference paper","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:a01bfe41-b87f-410a-afc6-a932ecf48923","http://resolver.tudelft.nl/uuid:a01bfe41-b87f-410a-afc6-a932ecf48923","Tests with a six degrees of freedom forced oscillator to investigat the nonlinear effects in ship motions","de Jong, Pepijn; Keuning, J.A.","","2005","","hydrodynamics","","conference paper","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:a91fa495-1966-49d1-9d31-3780fb961d11","http://resolver.tudelft.nl/uuid:a91fa495-1966-49d1-9d31-3780fb961d11","Tests with six degrees of freedom forced oscillator to investigate the nonlinear effects in ship motions","de Jong, Pepijn; Keuning, Jan Alexander","","2005","","proceedings","","conference paper","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","","","",""
"uuid:115cae1a-f944-4a8e-a266-c1fd18abaf99","http://resolver.tudelft.nl/uuid:115cae1a-f944-4a8e-a266-c1fd18abaf99","The Development of Velocity Prediction Program for Traditional Dutch Sailing Vessels of the Type Skûtsje","de Jong, Pepijn; Katgert, Michiel; Keuning, Lex","","2008","","yachting","","conference paper","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:c568dedd-ae33-4f1d-ba1b-4ff8fea81291","http://resolver.tudelft.nl/uuid:c568dedd-ae33-4f1d-ba1b-4ff8fea81291","Customary land tenure dynamics at peri-urban Ghana: Implications for land administration system modeling","Arko-Adjei, A.; de Jong, J.; Zevenbergen, J.A.; Tuladhar, A.M.","","2009","Customary land tenure is criticized as dynamic with the institutional framework unable to provide enough tenure security at all times. It is also criticized as ineffective to cope with the trends in land tenure delivery at peri-urban areas where individualization of land and demand for land is high. The aim of this paper is to investigate how customary land tenure systems of Ghana meet the dynamic need of the modern life in peri-urban areas. The study used a mixture of qualitative and quantitative methods including general and in-depth interviews, oral narrations, focus group discussions and questionnaires to collect and analyze data from stakeholders in three peri-urban areas of the three land owning groups in Ghana. The study shows that the institutional framework is resilient with the customary land tenure institutions maintaining their traditional power to allocate land and resolve land conflicts. The findings from the study have implications for land administration in peri-urban areas. Cadastres in these areas do not reflect the situation on the ground. The paper concludes that although dynamics of customary land tenure presents many challenges to the existing land administration system, it also has positive implications which provide framework for designing an alternative land administration system that can cope with the dynamics of customary land tenure.","customary land tenure dynamics; peri-urban areas; land administration","en","conference paper","FIG","","","","","","","","OTB Research Institute","","","","",""
"uuid:fb2555cb-07ca-4d77-9f99-0013f105e46e","http://resolver.tudelft.nl/uuid:fb2555cb-07ca-4d77-9f99-0013f105e46e","Uncertainty in Bollard Pull Predictions","Vrijdag, Arthur.; de Jong, Jochem; van Nuland, Hain","","2013","","resistance & propulsion","","conference paper","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:8af2535a-b902-47c0-8c41-04a116dee4fd","http://resolver.tudelft.nl/uuid:8af2535a-b902-47c0-8c41-04a116dee4fd","Loss modeling and analysis of the nuna solar car drive system","Arkesteijn, G.C.M.; de Jong, E.C.W.; Polinder, H.","","2007","","","en","conference paper","MC2D & MITI","","","","","","","","Electrical Engineering, Mathematics and Computer Science","","","","",""
"uuid:f884856a-aaa4-4301-ac02-9a661eaf7010","http://resolver.tudelft.nl/uuid:f884856a-aaa4-4301-ac02-9a661eaf7010","Time domain simulations of the behaviour of fast ships in oblique seas","van Walree, Frans; de Jong, Pepijn","","2008","","proceedings","","conference paper","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:1354e2fa-f8bb-482e-a097-9f0fed7b6742","http://resolver.tudelft.nl/uuid:1354e2fa-f8bb-482e-a097-9f0fed7b6742","Introducing a Dutch guideline on using the Observational Method","Bles, T.; Stoevelaar, R.; de Jong, E.","","2015","In the Netherlands research has been performed on the Observational Method, aiming at a wider use of the method in the design of underground and infrastructural construction works. This paper summarizes the guideline that was output of the research, providing a clear definition, an overview of obstacles and pre-conditions, practical recommendations on how to make a safe design while using the principles of Observational Method within the context of the Eurocode 7 and practical recommendations on how to organize the method during construction.","observational method; geo risk management; guideline; Eurocode 7; design; organization","en","conference paper","","","","","","","","","","","","","",""
"uuid:882023ef-13e2-425d-bd42-23162c734423","http://resolver.tudelft.nl/uuid:882023ef-13e2-425d-bd42-23162c734423","The Effect of Ship Speed, Heading Angle and Wave Steepness on the likelihood of Broaching-To in Astern Quartering Seas","de Jong, Pepijn; Renilson, Martin R.; van Walree, Frans","","2015","","hydrodynamics; Broaching-to; seakeeping and manoeuvring; time-domain panel method","","conference paper","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:9ce81849-8591-4f5d-9670-102a284a599c","http://resolver.tudelft.nl/uuid:9ce81849-8591-4f5d-9670-102a284a599c","The broaching of fast rescue craft in following seas","de Jong, P.; Renilson, M.R.; van Walree, F.","","2013","","hydrodynamics","","conference paper","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:d0dffe4f-bd99-4044-ab25-f4425d31120d","http://resolver.tudelft.nl/uuid:d0dffe4f-bd99-4044-ab25-f4425d31120d","Adaptive reuse in Dutch care accommodation","de Jong, P.; Remøy, H.T.; van der Voordt, D.J.M.; van der Kuij, R.S.","","2014","Purpose – Identifying opportunities for adaptive reuse in a changing (increasing market driven) context for Dutch care accommodation. Design/methodology/approach – Combination of two student thesis, both based on case study and decision model development. Findings – Due to new courses in the Dutch care industry functions of care accommodation are shifting, which could result in additional vacancy, unless the buildings are adaptable for the new situation. It is expected that new programs will be defined for the new care accommodations. However, one of the first lessons of transformation is to seek functions close to the original. With focus on adaptive reuse the problematic accommodations can be dedicated to closely related functions. The decision should be supported by a LCC?based comparative assessment.","adaptive reuse; care accommodation; LCC","en","conference paper","European Real Estate Society","","","","","","","","Architecture and The Built Environment","Management in the Built Environment","","","",""
"uuid:e4180cd9-2ef5-4eb8-80a8-83fa93494eae","http://resolver.tudelft.nl/uuid:e4180cd9-2ef5-4eb8-80a8-83fa93494eae","New wind-wave flumes at Delft","de Jong, J. (Delft Hydraulics)","","1969","On March 24, 1969, the new wind-wave flumes at the Delft Hydraulics Laboratory (Figures 5 and 6) were officially opened by the Director-General of the Rijkswaterstaat. The design work started in 1964, and the building and installations 1tlere completed in November 1968. A general description of this equipment and some insight into its underlying principles are given below.","physical model tests; scale models; wind waves","en","conference paper","","","","","","","","","","","","","",""
"uuid:57804874-f590-45b8-aac1-ace9a007cbad","http://resolver.tudelft.nl/uuid:57804874-f590-45b8-aac1-ace9a007cbad","Time domain simulations of the behaviour of fast ships in oblique seas","van Walree, Frans; de Jong, Pepijn","","2008","","hydrodynamics","","conference paper","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:61963329-4416-4cac-84ca-de55c6b38e3c","http://resolver.tudelft.nl/uuid:61963329-4416-4cac-84ca-de55c6b38e3c","Geographic data as personal data in four EU member states","de Jong, A.-J.; van Loenen, B. (TU Delft OLD Geo-information and Land Development); Zevenbergen, J.A. (University of Twente)","Halounova, L. (editor); Li, S. (editor); Safár, V. (editor); Tomková, M. (editor); Rapant, P. (editor); Brázdil, K. (editor); Shi, W. (editor); Anton, F. (editor); Liu, Y. (editor); Stein, A. (editor); Cheng, T. (editor); Pettit, C. (editor); Li, Q.-Q. (editor); Sester, M. (editor); Mostafavi, M.A. (editor); Madden, M. (editor); Tong, X. (editor); Brovelli, M.A. (editor); Haekyong, K. (editor); Kawashima, H. (editor); Coltekin, A. (editor)","2016","The EU Directive 95/46/EC on the protection of individuals with regard to the processing of personal data and on the free movement of such data aims at harmonising data protection legislation in the European Union. This should promote the free flow of products and services within the EU. This research found a wide variety of interpretations of the application of data protection legislation to geographic data. The variety was found among the different EU Member States, the different stakeholders and the different types of
geographic data. In the Netherlands, the Data Protection Authority (DPA) states that panoramic images of streets are considered personal data. While Dutch case law judges that the data protection legislation does not apply if certain features are blurred and no link to an address is provided. The topographic datasets studied in the case studies do not contain personal data, according to the
Dutch DPA, while the German DPA and the Belgian DPA judge that topographic maps of a large scale can contain personal data, and impose conditions on the processing of topographic maps. The UK DPA does consider this data outside of the scope of legal definition of personal data. The patchwork of differences in data protection legislation can be harmonised by using a traffic light
model. This model focuses on the context in which the processing of the data takes place and has four categories of data: (1) sensitive personal data, (2) personal data, (3), data that can possibly lead to identification, and (4) non-personal data. For some geographic data, for example factual data that does not reveal sensitive information about a person, can be categorised in the third
category giving room to opening up data under the INSPIRE Directive.","data protection; open data","en","conference paper","Copernicus","","","","","","","","","","OLD Geo-information and Land Development","","",""
"uuid:3534d831-f60b-4601-9825-8dde69edf12b","http://resolver.tudelft.nl/uuid:3534d831-f60b-4601-9825-8dde69edf12b","Continuous deployment and schema evolution in SQL databases","de Jong, Michael (Student TU Delft); van Deursen, A. (TU Delft Software Technology)","","2015","Continuous Deployment is an important enabler of rapid delivery of business value and early end user feedback. While frequent code deployment is well understood, the impact of frequent change on persistent data is less understood and supported. SQL schema evolutions in particular can make it expensive to deploy a new version, and may even lead to downtime if schema changes can only be applied by blocking operations. In this paper we study the problem of continuous deployment in the presence of database schema evolution in more detail. We identify a number of shortcomings to existing solutions and tools, mostly related to avoidable downtime and support for foreign keys. We propose a novel approach to address these problems, and provide an open source implementation. Initial evaluation suggests the approach is effective and sufficiently efficient.","","en","conference paper","Institute of Electrical and Electronics Engineers (IEEE)","","","","","","","","","Software Technology","","","",""
"uuid:abaad308-aacd-42f3-b1e1-0944f881ff6d","http://resolver.tudelft.nl/uuid:abaad308-aacd-42f3-b1e1-0944f881ff6d","Loosely coupled level sets for retinal layers and drusen segmentation in subjects with dry age-related macular degeneration","Novosel, J. (TU Delft ImPhys/Quantitative Imaging; Rotterdam Eye Hospital); Wang, Ziyuan; de Jong, Henk (Rotterdam Eye Hospital); Vermeer, K.A. (Rotterdam Eye Hospital); van Vliet, L.J. (TU Delft ImPhys/Quantitative Imaging)","Styner, Martin A. (editor); Angelini, Elsa D. (editor)","2016","Optical coherence tomography (OCT) is used to produce high-resolution three-dimensional images of the retina, which permit the investigation of retinal irregularities. In dry age-related macular degeneration (AMD), a chronic eye disease that causes central vision loss, disruptions such as drusen and changes in retinal layer thicknesses occur which could be used as biomarkers for disease monitoring and diagnosis. Due to the topology disrupting pathology, existing segmentation methods often fail. Here, we present a solution for the segmentation of retinal layers in dry AMD subjects by extending our previously presented loosely coupled level sets framework which operates on attenuation coefficients. In eyes affected by AMD, Bruch’s membrane becomes visible only below the drusen and our segmentation framework is adapted to delineate such a partially discernible interface. Furthermore, the initialization stage, which tentatively segments five interfaces, is modified to accommodate the appearance of drusen. This stage is based on Dijkstra's algorithm and combines prior knowledge on the shape of the interface, gradient and attenuation coefficient in the newly proposed cost function. This prior knowledge is incorporated by varying the weights for horizontal, diagonal and vertical edges. Finally, quantitative evaluation of the accuracy shows a good agreement between manual and automated segmentation.","Optical coherence tomography; attenuation coefficient; Dijkstra's algorithm","en","conference paper","SPIE","","","","","","","","","","ImPhys/Quantitative Imaging","","",""
"uuid:b3a3dff3-f44f-489c-8132-618590d83e4e","http://resolver.tudelft.nl/uuid:b3a3dff3-f44f-489c-8132-618590d83e4e","Optimalisatie van het wegontwerp van het luchtzijdige wegverkeerssysteem op de luchthaven Schiphol","de Jong, Eveline; Baggen, J.H. (TU Delft Transport and Logistics; TU Delft Transport and Planning); Knoop, V.L. (TU Delft Transport and Planning)","","2016","Het luchtzijdige wegverkeerssysteem op de luchthaven Amsterdam Airport Schiphol (Schiphol) is een niet-openbaar wegverkeerssysteem dat wordt gebruikt door afhandelaren van de vliegtuigen, bussen voor de passagiers en de ordehandhaving van de luchthaven. Naast een grote verscheidenheid aan voertuigen die we er aantreffen gelden er ook andere regels dan op de openbare weg. De problemen die ondervonden worden in de huidige situatie zijn vertragingen en verkeersongevallen. Het doel van dit paper is het vinden van een infrastructureel wegontwerp dat de effectiviteit van de randwegen rondom de pieren verbeterd. Daarbij wordt effectiviteit gemeten in reistijd, reisafstand, robuustheid, veiligheid, ruimtegebruik en kosten. De randwegen rondom de B-pier van Schiphol worden gebruikt als voorbeeldstudie, en om generieke inzichten te krijgen in de invloed van het wegontwerp worden ook twee generaliseerde netwerkvormen gebruikt. Het onderzoek biedt een overzicht van wegsectie- en knooppuntontwerpen die kunnen worden toegepast op wegverkeerssystemen gebaseerd op ontwerpen voor de openbare weg en wegontwerpen op andere vliegvelden. De combinaties van wegsectie- en knooppuntontwerpen worden toegepast op het netwerk van pier B in het verkeerssimulatiepakket VISSIM. De effecten op reistijd, reisafstand, robuustheid en veiligheid worden bepaald met de simulatieresultaten en voertuigtrajectanalyses in het surrogate safety assessment model (SSAM). Het ruimtegebruik en de kosten van de alternatieven zijn onderdeel van de ontwerpspecificaties. De uitkomst van het onderzoek is dat wegontwerpen allemaal ten minste één van de zes aspecten verbeteren ten opzichte van de basissituatie, dat er geen enkel alternatief is dat voor elk aspect het beste resultaat heeft en er dat er geen enkel alternatief is dat alle aspecten van de basissituatie verbetert. Een actorenanalyse laat zien dat de actoren verschillende belangen en interesses hebben, en dat het toepassen van gewichtensets per actorengroep resulteert in verschillende resultaten. Op basis van de beoordeling van de meerderheid van de actorengroepen is het ontwerp met tweerichtingsverkeer met voorrangsplein het beste ontwerp voor pier B.","","nl","conference paper","","","","","","","","","","","Transport and Logistics","","",""
"uuid:0c7f2aeb-f2d6-4c56-9ab7-5f47f73d133f","http://resolver.tudelft.nl/uuid:0c7f2aeb-f2d6-4c56-9ab7-5f47f73d133f","A Collaborative Approach to Teaching Software Architecture","van Deursen, A. (TU Delft Software Technology); Aniche, Maurício (TU Delft Software Engineering); Aué, Joop (Student TU Delft); Slag, R.G.J. (Student TU Delft); de Jong, M. (Student TU Delft); Nederlof, A. (Student TU Delft); Bouwers, E.M. (Student TU Delft)","","2017","Teaching software architecture is hard. The topic is abstract and is best understood by experiencing it, which requires proper scale to fully grasp its complexity. Furthermore, students need to practice both technical and social skills to become good software architects. To overcome these teaching challenges, we developed the Collaborative Software Architecture Course. In this course, participants work together to study and document a large, open source software system of their own choice. In the process, all communication is transparent in order to foster an open learning environment, and the end-result is published as an online book to benefit the larger open source community.
We have taught this course during the past four years to classes of 50-100 students each. Our experience suggests that: (1) open source systems can be successfully used to let students gain experience with key software architecture concepts, (2) students are capable of making code contributions to the open source projects, (3) integrators (architects) from open source systems are willing to interact with students about their contributions, (4) working together on a joint book helps teams to look beyond their own work, and study the architectural descriptions produced by the other teams.","","en","conference paper","Association for Computing Machinery (ACM)","","","","","","","","","Software Technology","Software Engineering","","",""
"uuid:a1fa43f9-9066-4f21-a199-56793f0d2614","http://resolver.tudelft.nl/uuid:a1fa43f9-9066-4f21-a199-56793f0d2614","Zero-Downtime SQL Database Schema Evolution for Continuous Deployment","de Jong, M. (Magnet.me); van Deursen, A. (TU Delft Software Technology); Cleve, Anthony (University of Namur)","","2017","When a web service or application evolves, its database schema — tables, constraints, and indices — often need to evolve along with it. Depending on the database, some of these changes require a full table lock, preventing the service from accessing the tables under change. To deal with this, web services are typically taken offline momentarily to modify the database schema. However with the introduction of concepts like Continuous Deployment, web services are deployed into their production environments every time the source code is modified. Having to take the service offline — potentially several times a day — to perform schema changes is undesirable. In this paper we introduce QuantumDB— a tool-supported approach that abstracts this evolution process away from the web service without locking tables. This allows us to redeploy a web service without needing to take it offline even when a database schema change is necessary. In addition QuantumDB puts no restrictions on the method of deployment, supports schema changes to multiple tables using changesets, and does not subvert foreign key constraints during the evolution process. We evaluate QuantumDB by applying 19 synthetic and 95 industrial evolution scenarios to our open source implementation of QuantumDB. These experiments demonstrate that QuantumDB realizes zero- downtime migrations at the cost of acceptable overhead, and is applicable in industrial continuous deployment contexts.","Databases; Web services; Servers; Switches; Tools","en","conference paper","IEEE","","","","","","","","","Software Technology","","","",""
"uuid:f351c546-d6d3-47b1-a221-7b0e3a21d53d","http://resolver.tudelft.nl/uuid:f351c546-d6d3-47b1-a221-7b0e3a21d53d","Needle deflection in thermal ablation procedures of liver tumors: a CT image analysis","de Jong, T.L. (TU Delft Medical Instruments & Bio-Inspired Technology); Klink, Camiel (Erasmus MC); Moelker, Adriaan (Erasmus MC); Dankelman, J. (TU Delft Medical Instruments & Bio-Inspired Technology); van den Dobbelsteen, J.J. (TU Delft Medical Instruments & Bio-Inspired Technology)","Fei, B (editor); Webster III, RJ (editor)","2018","Introduction: Accurate needle placement is crucial in image-guided needle interventions. A targeting error may be introduced due to undesired needle deflection upon insertion through tissue, caused by e.g. patient breathing, tissue heterogeneity, or asymmetric needle tip geometries. This paper aims to quantify needle deflection in thermal ablation procedures of liver tumors by means of a CT image analysis. Methods: Needle selection was done by using all clinical CT data that were made during thermal ablation procedures of the liver, ranging from 2008-2016, in the Erasmus MC, the Netherlands. The 3D needle shape was reconstructed for all selected insertions using manual segmentation. Subsequently, a straight line was computed between the entry point of the needle into the body and the needle tip. The maximal perpendicular distance between this straight line and the actual needle was used to calculate needle deflection. Results: In total, 365 needles were included in the analysis ranging from 14G to 17G in diameter. Average needle insertion depth was 95mm (range: 32 mm – 182 mm). Needle deflection was on average 1.3 mm (range: 0.0 mm – 6.5 mm). 54% of the needles (n=196) had a needle deflection of more than one millimeter, whereas 7% of the needles (n=25) showed a large needle deflection of more than three millimeters.
Conclusions: Needle deflection in interventional radiology occurs in more than half of the needle insertions. Therefore, deflection should be taken into account when performing procedures and when defining design requirements for novel needles. Further, needle insertion models need to be developed that account for needle deflection.","bending; deflection; interventional radiology; MW; needles; RFA; thermal ablation","en","conference paper","SPIE","","","","","","","","","","Medical Instruments & Bio-Inspired Technology","","",""
"uuid:99097a4e-529e-466c-ab6d-6ed5c06a85a1","http://resolver.tudelft.nl/uuid:99097a4e-529e-466c-ab6d-6ed5c06a85a1","Deep sub-wavelength metrology for advanced defect classification","van der Walle, P (TNO); Kramer, E. (TNO); van der Donck, J.C.J. (TNO); Mulckhuyse, W (TNO); Nijsten, L. (TNO); Bernal Arango, F.A. (TU Delft QN/Kuipers Lab; TNO); de Jong, A. (TNO); van Zeijl, E. (TNO); Spruit, H. E.T. (TNO); van den Berg, J.H. (TNO); Nanda, G. (TU Delft QN/Kavli Nanolab Delft); van Langen-Suurling, A.K. (TU Delft QN/Kavli Nanolab Delft; Kavli institute of nanoscience Delft); Alkemade, P.F.A. (TU Delft QN/Kavli Nanolab Delft; Kavli institute of nanoscience Delft); Pereira, S.F. (TU Delft ImPhys/Optics); Maas, D.J. (TNO)","Lehmann, Peter (editor); Osten, Wolfgang (editor); Albertazzi Gonçalves, Armando (editor)","2017","Particle defects are important contributors to yield loss in semi-conductor manufacturing. Particles need to be detected and characterized in order to determine and eliminate their root cause. We have conceived a process flow for advanced defect classification (ADC) that distinguishes three consecutive steps; detection, review and classification. For defect detection, TNO has developed the Rapid Nano (RN3) particle scanner, which illuminates the sample from nine azimuth angles. The RN3 is capable of detecting 42 nm Latex Sphere Equivalent (LSE) particles on XXX-flat Silicon wafers. For each sample, the lower detection limit (LDL) can be verified by an analysis of the speckle signal, which originates from the surface roughness of the substrate. In detection-mode (RN3.1), the signal from all illumination angles is added. In review-mode (RN3.9), the signals from all nine arms are recorded individually and analyzed in order to retrieve additional information on the shape and size of deep sub-wavelength defects. This paper presents experimental and modelling results on the extraction of shape information from the RN3.9 multi-azimuth signal such as aspect ratio, skewness, and orientation of test defects. Both modeling and experimental work confirm that the RN3.9 signal contains detailed defect shape information. After review by RN3.9, defects are coarsely classified, yielding a purified Defect-of-Interest (DoI) list for further analysis on slower metrology tools, such as SEM, AFM or HIM, that provide more detailed review data and further classification. Purifying the DoI list via optical metrology with RN3.9 will make inspection time on slower review tools more efficient.","advanced defect classification; dark field microscopy; defect detection; defect review; latex sphere equivalent; Particle contamination; semiconductor; speckle","en","conference paper","SPIE","","","","","","","","","","QN/Kuipers Lab","","",""
"uuid:651cf9c9-391c-4f7d-9a3f-a79b393711e3","http://resolver.tudelft.nl/uuid:651cf9c9-391c-4f7d-9a3f-a79b393711e3","Investigation of Statistical Distribution of Energization Overvoltages in 380 kV Hybrid OHL-Cable Systems","Khalilnezhad, H. (TU Delft Intelligent Electrical Power Grids); Popov, M. (TU Delft Intelligent Electrical Power Grids); Bos, Jorrit A. (TenneT TSO B.V.); de Jong, JPW (TenneT TSO B.V.); van der Sluis, L. (TU Delft EEMS - General)","","2018","Switching operations in power systems can produce significant overvoltages under specific circumstances. With the increasing application of underground cables in transmission systems, the statistical distribution of energization overvoltages is expected to change substantially due to the different electrical characteristics of cables and OHLs. Therefore, it is crucial to perform an insulation coordination study by analysis of the statistical distribution of energization overvoltages. This paper presents a statistical switching analysis on a hybrid OHL-Cable circuit to investigate how such hybrid circuits can affect the distribution of overvoltages. The literature has addressed the distribution of energization overvoltages only for OHLs or cables, but such an study is not available for hybrid systems consisting of OHLs and cables combined. The study is carried out for different cable lengths in the case study to identify how an increasing cable share in the circuit influences the overvoltages distribution due to no-load energization. Moreover, the impact of symmetrical and asymmetrical circuit structures is also addressed. The study is carried out on a distributed frequency-dependent parameter model of the Dutch 380 kV grid in PSCAD/EMTDC.","Cable; energization; insulation coordination; switching overvoltage; statistical switching","en","conference paper","","","","","","Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2021-08-17","","","Intelligent Electrical Power Grids","","",""
"uuid:71675a2f-65fa-47ce-8fb7-8c1540fc96cf","http://resolver.tudelft.nl/uuid:71675a2f-65fa-47ce-8fb7-8c1540fc96cf","Open Source Urbanism: Requirements for an Open Design Platform to Support an Emerging Concept","Zhilin, S. (TU Delft Organisation & Governance); Klievink, A.J. (TU Delft Organisation & Governance); de Jong, W.M. (TU Delft Organisation & Governance)","","2018","Citizens interested in the democratization of urban development processes experiment with the co-creation of public spaces. Some of them collect, improve, and share design blueprints and manuals of their projects on the internet with help of free and open source tools. As a result, they produce open source design manuals that can be used freely, modified, and developed further. However, such attempts at opening urban design are still uncoordinated, atomized, and dispersed, and therefore fail to create the value that a more concerted effort might. We argue that open source urbanism practices would benefit from open design platforms that are purposefully designed for the complex domain of urbanism. As a first step, this paper identifies the requirements that such platform should meet. As there are currently no examples of such a platform, we analyze the platforms that are there and partially satisfy the demand to extract the shared underlying requirements","open source; urban design; commons; co-production; open design platforms","en","conference paper","","","","","","","","","","","Organisation & Governance","","",""
"uuid:fcc9a011-1ae8-45e3-b2c3-eb7918f44895","http://resolver.tudelft.nl/uuid:fcc9a011-1ae8-45e3-b2c3-eb7918f44895","Feasibility of ultrasound flow measurements via non-linear wave propagation","Massaad Mouawad, J.M. (TU Delft ImPhys/Acoustical Wavefield Imaging); van Neer, P.L.M.J. (TU Delft ImPhys/Acoustical Wavefield Imaging; TNO); van Willigen, D.M. (TU Delft Electronic Instrumentation); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation); Verweij, M.D. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC)","Hashimoto, K. (editor); Ruppel, C. (editor)","2018","Typically, ultrasonic flow meters assume linear wave propagation. Nevertheless, if the transducers of an ultrasonic flow sensor excite a pressure wave with a high amplitude, nonlinear wave propagation effects become significant. The appearance of higher harmonics increases the bandwidth of the received signal, which may potentially lead to a more precise flow measurement. However, the question arises whether the increased bandwidth can be used in practice, since the intensity of the 2nd harmonic can be 25 dB below the fundamental. One exploit of the increased bandwidth is to filter the received signals and to obtain two components: the fundamental and the 2nd harmonic. Differences between the upstream and downstream transit times are directly related to the flow speed, and these can be computed for each component of the received signals. This paper shows that averaging the transit time differences of the fundamental signals and the 2nd harmonic signals results in a lower standard deviation compared to the standard deviation of the transit time differences of the fundamental or the 2nd harmonic signal alone. This demonstrates the feasibility of using non-linear wave propagation to improve the precision of flow measurements using ultrasound.","flow; non-linearity; ultrasound; precision","en","conference paper","IEEE","","","","","Accepted Author Manuscript","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:32a35ba0-d3f9-4681-8fee-59134e87466a","http://resolver.tudelft.nl/uuid:32a35ba0-d3f9-4681-8fee-59134e87466a","CaptureBias: Supporting Media Scholars with Ambiguity-Aware Bias Representation for News Videos","de Jong, M. (TU Delft Web Information Systems); Mavridis, P. (Vrije Universiteit Amsterdam); Aroyo, Lora (Universiteit Leiden); Bozzon, A. (TU Delft Web Information Systems); Vos, Jesse de (Nederlands Instituut voor Beeld en Geluid); Oomen, Johan (Nederlands Instituut voor Beeld en Geluid); Dimitrova, Antoaneta (Universiteit Leiden); Badenoch, Alec (Universiteit Utrecht)","Aroyo, Lora (editor); Dumitrache, Anca (editor); Paritosh, Praveen (editor); Quinn, Alex (editor); Welty, Chris (editor); Checco, Alessandro (editor); Demartini, Gianluca (editor); Gadiraju, Ujwal (editor); Sarasua, Cristina (editor)","2018","In this project we explore the presence of ambiguity in textual and visual media and its influence on accurately understanding and
capturing bias in news. We study this topic in the context of supporting
media scholars and social scientists in their media analysis. Our focus
lies on racial and gender bias as well as framing and the comparison
of their manifestation across modalities, cultures and languages. In this
paper we lay out a human in the loop approach to investigate the role of
ambiguity in detection and interpretation of bias.","Bias detection; bias in news video files; ambiguity-aware bias representation; disagreement; machine learning; crowdsourcing; human in the loop","en","conference paper","CEUR-WS","","","","","Accepted Author Manuscript","","","","","Web Information Systems","","",""
"uuid:df25feaa-5bd9-417b-96cb-db2e23fa22aa","http://resolver.tudelft.nl/uuid:df25feaa-5bd9-417b-96cb-db2e23fa22aa","A Human in the Loop Approach to Capture Bias and Support Media Scientists in News Video Analysis","Mavridis, P. (TU Delft Web Information Systems); de Jong, M. (Vrije Universiteit Amsterdam); Aroyo, Lora (Universiteit Leiden); Bozzon, A. (TU Delft Web Information Systems); Vos, Jesse de (Nederlands Instituut voor Beeld en Geluid); Oomen, Johan (Nederlands Instituut voor Beeld en Geluid); Dimitrova, Antoaneta (Universiteit Leiden); Badenoch, Alec (Universiteit Utrecht)","Aroyo, Lora (editor); Dumitrache, Anca (editor); Paritosh, Praveen (editor); Quinn, Alex (editor); Welty, Chris (editor); Checco, Alessandro (editor); Demartini, Gianluca (editor); Gadiraju, Ujwal (editor); Sarasua, Cristina (editor)","2018","Bias is inevitable and inherent in any form of communication. News often appear biased to citizens with dierent political orientations, and understood dierently by news media scholars and the broader public. In this paper we advocate the need for accurate methods for bias identication in video news item, to enable rich analytics capabilities in order to assist humanities media scholars and social political scientists. We propose to analyze biases that are typical in video news (including
framing, gender and racial biases) by means of a human-in-the-loop approach
that combines text and image analysis with human computation techniques.","Bias detection; bias in news video files; machine learning; crowdsourcing; human computation; human in the loop","en","conference paper","CEUR-WS","","","","","Accepted Author Manuscript","","","","","Web Information Systems","","",""
"uuid:a2250984-9ef3-4069-b871-cc3b7b33aa79","http://resolver.tudelft.nl/uuid:a2250984-9ef3-4069-b871-cc3b7b33aa79","Exploration and comparison of geothermal areas in Indonesia by fluid-rock geochemistry","Deon, F. (TU Delft Reservoir Engineering); Barnhoorn, A. (TU Delft Applied Geophysics and Petrophysics); Lievens, C. (University of Twente); Saptadij, N. (Bandung Institute of Technology ITB); Sutopo, S. (Bandung Institute of Technology ITB); van der Meer, F (University of Twente); den Hartog, T. (University of Twente); Brehmer, M (Helmholtz Centre Potsdam - GFZ German Research Centre for Geosciences); Bruhn, D.F. (TU Delft Reservoir Engineering); de Jong, M (Bandung Institute of Technology ITB); Ryannugroho, R. (Bandung Institute of Technology ITB); Hutami, R. (Bandung Institute of Technology ITB); Sule, R. (Bandung Institute of Technology ITB); Hecker, C. (University of Twente); Bonté, D (Universiteit Utrecht)","","2016","Indonesia with its large, but partially unexplored geothermal potential is one of the most interesting and suitable places in the world to conduct geothermal exploration research.
This study focuses on geothermal exploration based on fluid-rock geochemistry/geomechanics and aims to compile an overview on geochemical data-rock properties from important geothermal fields in Indonesia. The work will be conducted over the next two years and this paper intends to present the methods and approaches we would like to use. The research carried out in the field and in the laboratory is performed in the framework of the GEOCAP cooperation (Geothermal Capacity Building program Indonesia- the Netherlands). Research along with capacity building will be combined in this Indonesian-Dutch project. The application of petrology and geochemistry accounts to a better understanding of areas where operating power plants exist but also helps in the initial exploration stage of green areas. Because of their relevance and geological setting geothermal fields in Java, Sulawesi and the sedimentary basin of central Sumatra have been chosen as focus areas of this study. Operators, universities and governmental agencies will benefit from this approach as it will be applied also to new green-field regions and areas to be tendered.","geothermal exploration; capacity building; fluid chemistry and rock petrology","en","conference paper","","","","","","","","","","","Reservoir Engineering","","",""
"uuid:9706ce66-0439-4ecd-9ea2-6502f5f26ac7","http://resolver.tudelft.nl/uuid:9706ce66-0439-4ecd-9ea2-6502f5f26ac7","Experimental and numerical investigation on the heel and drift induced hydrodynamical loads of a high speed craft","Bonci, M. (TU Delft Ship Hydromechanics and Structures); de Jong, Pepijn (Maritime Research Institute Netherlands (MARIN)); van Walree, Frans (Maritime Research Institute Netherlands (MARIN)); Renilson, Martin (University of Tasmania); Keuning, J.A. (TU Delft Ship Hydromechanics and Structures); Huijsmans, R.H.M. (TU Delft Ship Hydromechanics and Structures)","","2017","In order to provide an insight into the manoeuvring of high speed crafts, an experimental study was undertaken at the towing tank of Delft University of Technology, using a rescue vessel of the Royal Netherlands Sea Rescue Institution (KNRM).
Design/methodology/approach – A theory-practice oriented approach is followed. Literature review is conducted to identify the need for a new economy that distances itself from the outdated neo-liberal models and gives space to a material-driven circular economy on the one hand and the more pragmatic life-cycle cost (total cost of ownership) approach on the other.
Findings – It seems that the donut economy offers the compass that the practice currently needs. It offers scope for making assumptions in a period in which people know which way things are going and at the same time want to have 'hard data'.
Quality/value – The study has the potential to support the university real estate management in its aim to meet their sustainable mission and to set a general approach. It will contribute to a larger research on this topic.","Total cost of ownership; Doughnut economics; Circular strategies","en","conference paper","","","","","","","","","","","Design & Construction Management","","",""
"uuid:0b0a9254-bfc3-4cc2-aa74-bd768b8b3b36","http://resolver.tudelft.nl/uuid:0b0a9254-bfc3-4cc2-aa74-bd768b8b3b36","Shunt Compensation Design of EHV Double-Circuit Mixed OHL-Cable Connections","Khalilnezhad, H. (TU Delft Intelligent Electrical Power Grids); Chen, S. (External organisation); Popov, M. (TU Delft Intelligent Electrical Power Grids); Bos, J.A. (TenneT TSO B.V.); de Jong, J.P.W. (TenneT TSO B.V.); van der Sluis, L. (TU Delft EEMS - General)","","2016","This paper deals with the shunt compensation design of long 380kV-50Hz XLPE cables by simulating a double-circuit partially cabled connection with the transmission length of 80km in the Dutch transmission system. The proposed procedure for shunt compensation sizing is fully elaborated in this paper. Four sizing criteria are used to find the minimum required size of compensation. All simulations are performed for different cable lengths. Moreover, different compensation arrangements including line-end and distributed arrangements are compared in terms of minimum required compensation size. Finally, the influence of mixed-line configuration, i.e. the number and the location of cable sections, on the minimum required compensation size is investigated by simulating five mixed-line configurations. All simulations are performed for two load-flow scenarios representing two extreme situations in the future planning of the Dutch transmission grid.
2, CH4, CO and CO2 were measured by means of gas chromatography (GC). A decrease in the char yield and an increase of the gas yield were observed when temperature increased. From 800°C on, it was observed that the char yield of samples Dig R and SW were constant, which indicated that the primary devolatilization reactions stopped. This fact was also corroborated by GC analysis. The bio-oil yield slightly increased with temperature, showing a maximum of 20.7 and 27.8 wt.% for samples Pre and SW, respectively, whereas sample Dig R showed a maximum yield of 16.5 wt.% at 800°C. CO2 and CO were the main released gases whereas H2 and CH4 production increased with temperature. Finally, an increase of char porosity was observed with temperature.","","en","conference paper","EDP Sciences","","","","","","","","","","Energy Technology","","",""
"uuid:55480c9b-2b77-4d38-97a9-bbda29d99229","http://resolver.tudelft.nl/uuid:55480c9b-2b77-4d38-97a9-bbda29d99229","Investigation of poultry litter conversion into useful energy resources using fast pyrolysis","Simbolon, L.M. (Brunel University); Pandey, D. S. (Brunel University; Anglia Ruskin University); Tsekos, C. (TU Delft Large Scale Energy Storage); de Jong, W. (TU Delft Large Scale Energy Storage; Rijksuniversiteit Groningen); Tassou, S. A. (Brunel University)","Scarlat, N. (editor); Grassi, A. (editor); Carvalho, M.d.G. (editor); Helm, P. (editor)","2019","The present study explored a thermochemical treatment method as an alternative approach to process animal feedlot (poultry litter). Fast pyrolysis of poultry litter experiments was conducted using a Pyroprobe 5200 reactor in the temperature range of 400-600 °C. The influence of reactor temperature on the yield of pyrolytic gases, condensate (bio-oil) and biochar yield was reported along with the mass balance. The biochar yield decreased consistently with an increase in temperature (from ~62 wt.% at 400 °C to ~ 40 wt.% at 600 °C), whereas the maximum bio-oil yield 23.2 wt.% was reported at 600 °C. The evolved pyrolytic gases were dominated by CO and CO2 and have shown an increasing trend with the temperature. Evolved gases were measured by a micro-gas Chromatograph. The yield of the liquid fraction (bio-oil) and biochar were quantified for the mass balance analysis. The yield of liquid and biochar are in agreement with previous work.","Animal residue; Biochar; Fast pyrolysis; Pyrolysis oil; Thermochemical conversion","en","conference paper","ETA-Florence Renewable Engergies","","","","","Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2020-01-01","","","Large Scale Energy Storage","","",""
"uuid:4ae5e757-eaa2-4aae-825a-ddca25448182","http://resolver.tudelft.nl/uuid:4ae5e757-eaa2-4aae-825a-ddca25448182","3-D contrast enhanced ultrasound imaging of an in vivo chicken embryo with a sparse array and deep learning based adaptive beamforming","Ossenkoppele, B.W. (TU Delft ImPhys/Imaging Physics; TU Delft ImPhys/Medical Imaging); Wei, Luxi (Erasmus MC); Luijten, Ben (Eindhoven University of Technology); Vos, H.J. (TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Van Sloun, Ruud J.G. (Eindhoven University of Technology; Philips Research); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC)","","2022","3-D contrast enhanced ultrasound enables better visualization of inherently 3-D vascular geometries compared to an intersecting plane. Additionally, it would allow the application of motion correction techniques for all directions. Both contrast detection and motion correction work better on high-frame rate data. However high-frame rate 3-D ultrasound imaging with dense matrix arrays is challenging to realize. Sparse arrays alleviate some of the limitations in cable count and data rate that fully populated arrays encounter, but their increased level of secondary lobes negatively impacts image contrast. Meanwhile the use of unfocused transmit beams needed to achieve high-frame rates negatively impacts resolution. Here we propose to use adaptive beamforming by deep learning (ABLE) to improve the image quality of contrast enhanced ultrasound images acquired with a sparse spiral array. We train the neural network on simulated data and evaluate simulated images and in vivo images of an ex ovo chicken embryo. ABLE improved resolution compared to delay-and-sum (DAS) and spatial coherence (SC) beamforming on the simulated and in vivo data. The qualitative improvements persist after histogram matching, indicating that the image quality improvement of the ABLE images was not purely due to dynamic range stretching.","beamforming; contrast enhanced ultrasound; deep learning; sparse array; spiral array","en","conference paper","IEEE","","","","","Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2023-07-01","","ImPhys/Imaging Physics","ImPhys/Medical Imaging","","",""
"uuid:436f77ab-7d34-405d-b7a4-de44c6d16623","http://resolver.tudelft.nl/uuid:436f77ab-7d34-405d-b7a4-de44c6d16623","A variational approach to determine the optimal power distribution for cycling in a time trial","de Jong, J. (Universiteit Utrecht); Fokkink, R.J. (TU Delft Applied Probability); Olsder, G.J. (TU Delft Discrete Mathematics and Optimization); Schwab, A.L. (TU Delft Biomechatronics & Human-Machine Control)","van der Helm, F.C.T. (editor); Jansen, A.J. (editor)","2016","The optimal pacing strategy of a cyclist in an individual time-trial depends on terrain, weather conditions and the cyclists endurance capacity. Previous experimental and theoretical studies have shown that a suboptimal pacing strategy may have a substantial negative effect. In this paper we express the optimal pacing problem as a mathematical optimal control problem which we solve using Pontryagin's maximum principle. Our solution of the pacing problem is partly numerical and partly analytical. It applies to a straight course without bends. It turns out that the optimal pacing problem is a singular control problem. Intricate mathematical arguments are required to prove that the singular control times form a single interval: optimal pacing starts with maximum power and decays through a singular control, which may be degenerate, to minimum power.","bicycling; maximum principle; power equation","en","conference paper","Elsevier","","","","","","","","","","Applied Probability","","",""
"uuid:251fdc1c-ae77-4c95-86b1-f73b8332da9b","http://resolver.tudelft.nl/uuid:251fdc1c-ae77-4c95-86b1-f73b8332da9b","A Pitch-Matched Transceiver ASIC for 3D Ultrasonography with Micro-Beamforming ADCs based on Passive Boxcar Integration and a Multi-Level Datalink","Guo, P. (TU Delft Bio-Electronics); Chang, Z.Y. (TU Delft Electronic Instrumentation); Noothout, E.C. (TU Delft ImPhys/Verweij group); Vos, H.J. (TU Delft ImPhys/Verweij group; Erasmus MC); Bosch, J. G. (Erasmus MC); de Jong, N. (TU Delft ImPhys/De Jong group; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; TU Delft ImPhys/Verweij group; Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation)","","2023","This paper presents a pitch-matched transceiver ASIC integrated with a 2-D transducer array for a wearable ultrasound device for transfontanelle ultrasonography. The ASIC combines 8-fold multiplexing, 4-channel micro-beamforming (μ BF) and sub-array-level digitization to achieve a 128-fold channel-count reduction. The μ BF is based on passive boxcar integration and interfaces with a 10-bit 40 MS/s SAR ADC in the charge domain, thus obviating the need for explicit anti-alias filtering and power-hungry ADC drivers. A compact and low-power reference generator employs an area-efficient MOS capacitor as a reservoir to quickly set a reference for the ADC in the charge domain. A low-power multi-level data link concatenates outputs of four ADCs, leading to an aggregate 3.84 Gb/s data rate. Per channel, the RX circuit consumes 2.06 mW and occupies 0.05 mm2.","","en","conference paper","Institute of Electrical and Electronics Engineers (IEEE)","","","","","Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2024-01-29","","","Bio-Electronics","","",""
"uuid:3b246b0f-485a-4de5-bd53-4d8809a7cdd0","http://resolver.tudelft.nl/uuid:3b246b0f-485a-4de5-bd53-4d8809a7cdd0","Acoustic Design of a Transducer Array for Ultrasonic Clamp-on Flow Metering","Massaad Mouawad, J.M. (TU Delft ImPhys/Acoustical Wavefield Imaging); van Willigen, D.M. (TU Delft Electronic Instrumentation); van Neer, P.L.M.J. (TU Delft ImPhys/Acoustical Wavefield Imaging); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation); Verweij, M.D. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC)","Cochran, Sandy (editor); Lucas, Margaret (editor)","2019","Current ultrasonic clamp-on flow meters are based on single-element transducers that require manual calibration by aligning these to a fixed acoustic path. Moreover, the size and operational frequency of the transducers cannot be adapted to the parameters of the pipe and the liquid, which are in practice not precisely known a priory. A set of two transducer arrays could be used to solve these issues. With an array, properties of the pipe and the liquid can be estimated before measuring flow. Furthermore, electronic beam steering can be used for auto-alignment of the acoustic beam, reducing the need for manual calibration. Moreover, an array allows for the use of signal processing to suppress the effects of spurious Lamb waves propagating in the pipe wall. This research work describes the acoustic design process of a transducer array for ultrasonic clamp-on flow measurements for a wide range of conditions. First, performance requirements are defined. Then, the design models are presented, and a step by step process of the acoustic stack design of the transducer array is described. At each design step, material dimensions are optimized to achieve a thickness resonance mode at 1 MHz within a bandwidth of interest between 0.2 MHz and 2 MHz. Finally, the expected performance of the designed array is reported, based on simulation results.","","en","conference paper","IEEE","","","","","Accepted Author Manuscript","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:380c6a8d-9b46-4304-b89a-c211b13b8862","http://resolver.tudelft.nl/uuid:380c6a8d-9b46-4304-b89a-c211b13b8862","3D high frame rate flow measurement using a prototype matrix transducer for carotid imaging","Fool, F. (TU Delft ImPhys/Acoustical Wavefield Imaging); Vos, H.J. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Shabanimotlagh, M. (TU Delft ImPhys/Acoustical Wavefield Imaging); Soozande, M. (TU Delft ImPhys/Acoustical Wavefield Imaging); Mozaffarzadeh, M. (TU Delft ImPhys/Acoustical Wavefield Imaging); Kim, T. (TU Delft Electronic Instrumentation); Kang, E. (TU Delft Electronic Instrumentation); Pertijs, M.A.P. (TU Delft Electronic Instrumentation); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC)","Cochran, Sandy (editor); Lucas, Margaret (editor)","2019","To accurately investigate the state of the carotid artery by the local haemodynamics and motion of the plaque using ultrasound, high-frame rate volumetric imaging is necessary. We have specifically designed a matrix array for this purpose. In this proceeding we will focus on imaging a volumetric flow profile using this matrix. For this purpose, we extend a fast frequency domain vector flow imaging method to 3D and perform measurements on a flow phantom. The results indicate that it is feasible to estimate 3D velocity vectors on a 3D grid using our matrix transducer and the proposed algorithm.","Fourier domain algorithm; Matrix array; Plane wave imaging; Vector velocity imaging; Volumetric flow","en","conference paper","IEEE","","","","","Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2020-06-09","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:793197b3-666a-4f43-b031-0beff49f32a6","http://resolver.tudelft.nl/uuid:793197b3-666a-4f43-b031-0beff49f32a6","A 1.2mW/channel 100m-Pitch-Matched Transceiver ASIC with Boxcar-Integration-Based RX Micro-Beamformer for High-Resolution 3D Ultrasound Imaging","Guo, P. (TU Delft Electronic Instrumentation); Fool, F. (TU Delft ImPhys/Medical Imaging); Noothout, E.C. (TU Delft ImPhys/Medical Imaging); Chang, Z.Y. (TU Delft Electronic Instrumentation); Vos, H.J. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Bosch, Johan G. (Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation)","Fujino, Laura C. (editor)","2022","The integration of 2D ultrasonic transducer arrays and pitch-matched ASICs has enabled the realization of various 3D ultrasound imaging devices in recent years [1]-[3]. As applications such as 3D intravascular ultrasonography, intra-cardiac echocardiography, and trans-fontanelle ultrasonography call for miniaturization and improved spatial resolution, higher-frequency transducers (>5MHz) with a correspondingly smaller array pitch (<150m) are needed. Such devices generally employ a large number of transducer elements, calling for channel-count reduction in the ASIC while meeting stringent restrictions on per-element power consumption and die area. Micro-beamforming (BF) is an effective way of reducing channel count by performing a delay-and-sum operation on the echo signals received within a sub-array [1]. However, prior BF implementations employ per-element capacitive memory to realize the delay [1], [2], making it increasingly difficult to apply BF in smaller-pitch arrays.","","en","conference paper","IEEE","","","","","Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2023-07-01","","","Electronic Instrumentation","","",""
"uuid:874ab466-b501-4909-9401-e97ffeb738d2","http://resolver.tudelft.nl/uuid:874ab466-b501-4909-9401-e97ffeb738d2","Large Matrix Array Aperture for 3D Vascular Imaging Capture","Colas, Quorentin (VERMON); Bantignies, Claire (VERMON); Perroteau, Marie (VERMON); Porcher, Nicolas (VERMON); Vassal, Steeven (VERMON); Bosch, Johan G. (Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging); Verweij, M.D. (TU Delft ImPhys/Medical Imaging); Pertijs, M.A.P. (Erasmus MC)","","2022","Three-dimensional ultrasound has initially been used to address volumetric imaging for diagnostic purposes and represents the leading-edge technological orientation in both transducer and IC (integrated circuit) architecture and design. However, new applications are coming up like biomarker measurements, preoperative navigation, real time surgery guidance or therapeutic procedures where 3D ultrasound modalities are key but their design objectives may need to be thought outside 3D echocardiography and radiology technological trade-offs. For those new applications, system architectures would need less complexity and imaging performances enabling easier hardware reconfigurability tailored to application-oriented imaging. This paper presents an ongoing development where a large matrix transducer has been assembled with multiple ASIC dies in a reconfigurable way. The transducer has a central frequency of 8MHz, a square pitch of 150μm× 150μm capable to fully image the upper carotid window thanks to a large aperture of 80×240 elements, resulting in a transducer active footprint of 12×36 square millimeters.","3D; ASIC integration; Matrix array; reconfigurable; transducer","en","conference paper","IEEE","","","","","Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2023-07-01","","","ImPhys/Medical Imaging","","",""
"uuid:27860187-b263-4e98-a423-8f8629891116","http://resolver.tudelft.nl/uuid:27860187-b263-4e98-a423-8f8629891116","Experimental Investigation of the Effect of Subdicing on an Ultrasound Matrix Transducer","Simoes dos Santos, D. (TU Delft ImPhys/Medical Imaging); Fool, F. (TU Delft ImPhys/Medical Imaging); Kim, Taehoon (Student TU Delft); Noothout, E.C. (TU Delft ImPhys/Medical Imaging); Vos, H.J. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Bosch, Johan G. (Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC)","","2021","Over the past decades, real-time three-dimensional (3D) medical ultrasound has attracted much attention since it enables clinicians to diagnose more accurately. This calls for ultrasound matrix transducers with a large number of elements, which can be interfaced with an application-specific integrated circuit (ASIC) for data reduction. An important aspect of the design of such a transducer is the geometry of each element, since it affects the mode of vibration and, consequently, the efficiency of the transducer. In this paper, we experimentally investigate the effect of subdicing on a piezoelectric (PZT) transducer. We fabricate and acoustically characterize a prototype PZT matrix transducer built on top of ASICs. The prototype transducer contains subdiced and non-subdiced elements, whose performance can be directly compared under the same conditions. Measurement results show that subdiced elements have a better performance compared to non-subdiced ones. Subdicing increases the peak pressure by 25%, raises the bandwidth by 10% and reduces the ringing time by 25%.","ASIC; PZT; matrix; subdicing; ultrasound transducer","en","conference paper","IEEE","","","","","Accepted Author Manuscript","","","","","ImPhys/Medical Imaging","","",""
"uuid:9fb77013-6acb-4f12-b26c-883aa1cbb588","http://resolver.tudelft.nl/uuid:9fb77013-6acb-4f12-b26c-883aa1cbb588","A Pitch-Matched ASIC with Integrated 65V TX and Shared Hybrid Beamforming ADC for Catheter-Based High-Frame-Rate 3D Ultrasound Probes","Hopf, Y.M. (TU Delft Electronic Instrumentation); Ossenkoppele, B.W. (TU Delft ImPhys/Medical Imaging); Soozande, M. (Erasmus MC); Noothout, E.C. (TU Delft ImPhys/Medical Imaging); Chang, Z.Y. (TU Delft Electronic Instrumentation); Chen, C. (TU Delft Electronic Instrumentation); Vos, H.J. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Bosch, J.G. (Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation)","Fujino, Laura C. (editor)","2022","Intra-cardiac echography (ICE) probes (Fig. 32.2.1) are widely used in electrophysiology for their good procedure guidance and relatively safe application. ASICs are increasingly employed in these miniature probes to enhance signal quality and reduce the number of connections needed in mm-diameter catheters [1]-[5]. 3D visualization in real-time is additionally enabled by 2D transducer arrays with, for each transducer element, a high-voltage (HV) transmit (TX) part, to generate acoustic pulses of sufficient pressure, and a receive (RX) path, to process the resulting echoes. To achieve the required reduction in RX channels, micro-beamforming (BF), which merges the signals from a subarray using a delay-and-sum operation, has been shown to be an effective solution [3], [4]. However, due to the frame-rate reduction that is associated with BF, these designs cannot serve emerging high-frame-rate imaging modes (1000 volumes/s) like 3D blood-flow and elastography imaging. In-probe digitization has recently been investigated to provide further channel-count reduction, make data transmission more robust, and enable pre-processing in the probe [1]-[3]. However, these earlier designs have either no TX functionality [2], [3] or only low-voltage (LV) TX [1] integrated. Combining BF and digitization with area-hungry HV transmitters in a pitch-matched scalable fashion while supporting high-frame-rate imaging remains an unmet challenge. The work presented in this paper meets this target, enabled by a hybrid ADC, the small die size of which allows for co-integration with 65V element-level pulsers.","Low voltage; Three-dimensional displays; Transducers; Ultrasonic imaging; Array signal processing; Transmitters; Imaging","en","conference paper","IEEE","","","","","Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2023-07-01","","","Electronic Instrumentation","","",""
"uuid:15292a42-e50e-46c7-b44d-64ac98f9fbac","http://resolver.tudelft.nl/uuid:15292a42-e50e-46c7-b44d-64ac98f9fbac","Een beslissingsondersteunend systeem voor de strategische planning van de inzet van schepen bij Scaldis Reefer Chartering (summary)","de Jong, H.E.M.","","1995","","","","doctoral thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:80f45e0a-c106-4ec0-9c39-b703c4b09f47","http://resolver.tudelft.nl/uuid:80f45e0a-c106-4ec0-9c39-b703c4b09f47","Three-dimensional integration of power electronic converters on printed circuit board","de Jong, E.C.W.","","2007","The current construction technology for PCB assembled power converters is based on the assembly of pre-manufactured discrete components. Fundamental limits of this construction method are steadily being reached as power converters tend to exploit higher processing speeds to gain advantages in both magnetic component size and overall power density. This thesis investigates a new design approach encompassing thermal management, geometrical packaging and electromagnetic integration (focussing on the PCB in particular) to push the limits further. In the research, a quantitative means to deal with component layout and the effect it has on the temperature characteristic of the converter is introduced as design tool.It incorporates the ability to define a design objective, such as high power density or increased reliability, and to weigh the respective trade-offs encountered during thermal design of a converter. Examples are provided. Furthermore, the inherent limitation of 2D component layout (rigid PCB) often limits the freedom to arrange components with compatible shapes tightly together. A geometrical packaging approach is investigated to alleviate this limitation and thereby improve power density. Compatible components can be arranged tightly together in 3D by implementing flexible PCB to fold the circuit, to accommodate the components. Electromagnetic integration has been identified as the enabling factor to realise structures that combine the functionality of several, otherwise discrete, components into a single structure, and combined with rigid-flex PCB technology these structures can be seamlessly embedded within the geometrically packaged converter system. The implementation of such multi-functional structures decreases the number of production and assembly steps during manufacturing and provides cost savings in material and assembly of the converter. The design procedure that encompasses the electrical, thermal and spatial aspects of compact PCB assembled converters is described and illustrated by working through the complete design of a 3D PCB converter technology demonstrator.","thermal management; geometrical packaging; electromagnetic integration","en","doctoral thesis","","","","","","","","","Electrical Engineering, Mathematics and Computer Science","","","","",""
"uuid:6d8e8c2c-7ba0-4cd5-9301-40c4661b351f","http://resolver.tudelft.nl/uuid:6d8e8c2c-7ba0-4cd5-9301-40c4661b351f","Microscopic Dynamics and Structure of Liquid Lithium and Liquid Lithium-Based Alloys","de Jong, P.H.K.","de Graaf, L.A. (promotor); van der Lugt, W. (promotor)","1993","","inelastic neutron scattering; neutron diffraction; dynamics","en","doctoral thesis","","","","","","","","","Applied Sciences","","","","",""
"uuid:e6b77de2-e930-4741-b26d-fcb8a672306b","http://resolver.tudelft.nl/uuid:e6b77de2-e930-4741-b26d-fcb8a672306b","Een beslissingsondersteunend systeem voor de strategische planning van de inzet van schepen bij Scaldis Reefer Chartering","de Jong, H.E.M.","","1995","","","","doctoral thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:1f8de5ab-d231-4486-b4d5-6557e324237b","http://resolver.tudelft.nl/uuid:1f8de5ab-d231-4486-b4d5-6557e324237b","On the optimization and the design of ship screw propellers with and without end plates","de Jong, Karel","","1991","","resistance & propulsion","","doctoral thesis","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:d19d1369-5259-4052-91e8-22a334be26d3","http://resolver.tudelft.nl/uuid:d19d1369-5259-4052-91e8-22a334be26d3","An Adaptive Trip Planning Support Environment","de Jong, R.","Sol, H.G. (promotor); Hamerslag, R. (promotor)","1992","","logistiek; informatiesystemen","en","doctoral thesis","","","","","","","","","Electrical Engineering, Mathematics and Computer Science","","","","",""
"uuid:239bdb2c-b59f-40d2-91b7-367139dbad13","http://resolver.tudelft.nl/uuid:239bdb2c-b59f-40d2-91b7-367139dbad13","Renovation techniques for fatigue cracked orthotropic steel bridge decks","de Jong, F.B.P.","Bijlaard, F.S.K. (promotor)","2007","This dissertation presents the research into renovation techniques for orthotropic steel bridge decks. These techniques are needed to solve fatigue problems in the decks of these bridges, as several fatigue cracks have been detected in the deck structure of these bridges the last decade. A well-known example of fatigue cracks are those observed in the deck plate of the Van Brienenoord bascule bridge in 1997, at that time a 7 year old bridge. The renovation techniques are part of a proposed maintenance philosophy for steel bridge decks. Lifetime calculations, inspections and renovation techniques are the three essential parts of this philosophy. A reliable lifetime calculation model for fatigue damage in the deck plate is described, including the influence of the asphalt surfacing. Accurate calculation results are obtained, both for movable and fixed bridges. Inspection programs can be based on the lifetime calculation results. Several innovative inspection techniques are presented briefly. For fixed bridges the replacement of the asphalt surfacing with a reinforced high performance concrete surfacing is an effective renovation method. For movable bridge decks three solutions that extend the lifetime of the orthotropic deck structure were researched in this thesis.","orthotropic; steel; bridge; fatigue; renovation; inspection; maintenance; high performance concrete","en","doctoral thesis","","","","","","","","","Civil Engineering and Geosciences","","","","",""
"uuid:045e3bff-8d8e-496c-99a5-4e1387be2163","http://resolver.tudelft.nl/uuid:045e3bff-8d8e-496c-99a5-4e1387be2163","Institutional Transplantation - How to adopt good transport infrastructure decision-making ideas from other countries?","de Jong, W.M.","ten Heuvelhof, E.F. (promotor)","1999","","","en","doctoral thesis","","","","","","","","","Technology, Policy and Management","","","","",""
"uuid:5c917e38-7baa-480f-9b28-97e2428ac8ee","http://resolver.tudelft.nl/uuid:5c917e38-7baa-480f-9b28-97e2428ac8ee","Characterization of Coatings inside Food and Beverage Cans","de Jong, A.J.","de Wit, J.H.W. (promotor)","2000","","","en","doctoral thesis","Delft University Press","","","","","","","","Applied Sciences","","","","",""
"uuid:a9382f3c-1b84-4b15-90e2-1d511af296a9","http://resolver.tudelft.nl/uuid:a9382f3c-1b84-4b15-90e2-1d511af296a9","Seakeeping behavior of high speed ships – An experimental and numerical study","de Jong, Pepijn","","2011","","scientific publications","","doctoral thesis","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:281ae9c5-9ca2-4dce-aa72-39d5d16c5475","http://resolver.tudelft.nl/uuid:281ae9c5-9ca2-4dce-aa72-39d5d16c5475","Some aspects of ship motions in irregular beam and longitudinal waves","de Jong, Bart","","1970","","hydrodynamics","","doctoral thesis","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:34375ba6-4ea9-4d66-905a-b8d311d5dfa4","http://resolver.tudelft.nl/uuid:34375ba6-4ea9-4d66-905a-b8d311d5dfa4","Structural and mechanistic aspects of quinohaemoprotein ethanol dehydrogenase from Comamonas testosteroni","de Jong, G.A.H.","Duine, J.A. (promotor)","1995","","","en","doctoral thesis","","","","","","","","","Applied Sciences","","","","",""
"uuid:9cd36947-5e27-4436-9bbb-d7fc5daa6047","http://resolver.tudelft.nl/uuid:9cd36947-5e27-4436-9bbb-d7fc5daa6047","Gate-based readout of hybrid quantum dot systems","de Jong, D. (TU Delft BUS/Quantum Delft)","Kouwenhoven, Leo P. (promotor); Vandersypen, L.M.K. (promotor); Delft University of Technology (degree granting institution)","2021","Quantum mechanics yields exciting opportunities for developing novel technologies. In particular, quantum computation enables performing otherwise intractable calculations. However, unwanted disturbances to the quantum bits (qubits) form a formidable challenge for its implementation. Topologically encoding information protects against these disturbances. Qubits based on Majorana zero modes are promising for achieving topological protection and form a model application for the results of this thesis. This thesis focuses on gate-based sensing, a scalable and high-fidelity readout mechanism for solid-state quantum information processing devices. We investigate semiconductor/superconductor hybrid quantum dot devices implemented in InAs nanowires. Radio frequency (RF) techniques allow rapid and multiplexed measurements of mesoscopic systems without relying on DC-transport. As such, we show that RF measurements provide a vital tool for rapid readout and quick tune-up of semiconductor qubits. We start by presenting the theoretical foundations of quantum dots and resonators, necessary for describing the subsequent experimental results. Next, we provide relevant details concerning the experiments in this thesis. The first experiment shows the implementation of dispersive gate sensing (DGS) in a semiconductor double quantum dot (DQD). We show dispersive shifts on the order of the resonator linewidth and study its behavior for different readout powers. These shifts match theoretical expectations and allow differentiating between Coulomb blockade and resonance with a signal-to-noise ratio (SNR) of 2 within \SI{1}{\micro\second}. We subsequently apply DGS to a semiconducting quantum dot coupled to a superconducting island and observe spin-dependent tunneling and simultaneous two-particle tunneling involving Cooper pairs. By inhibiting electron tunneling to the outside leads, we bring the system to an otherwise inaccessible regime and show that DGS can probe floating systems. The third experiment replaces the MHz-resonators with on-chip superconducting coplanar waveguide resonators in the GHz regime. We extract the differential conductance quantitatively without relying on any DC calibration data. Furthermore, we obtain an SNR of 15 in 1 microsecond distinguishing Coulomb blockade from resonance in a semiconductor DQD. In the final experiment, we combine the preceding experimental results and investigate a superconducting island between two semiconductor quantum dots. We can split single Cooper pairs on demand with this geometry while retaining the resulting electrons. Secondly, we measure the electron parity using gate-based sensing in a DQD without external charge sensors. This thesis concludes by discussing the relevance of the obtained experimental results to the Majorana box qubit and suggestions for subsequent experiments. The results of this thesis show that gate-based sensing is a versatile tool in the context of mesoscopic experiments and quantum information processing devices in particular.","","en","doctoral thesis","","978-90-8593-499-8","","","","","","","","","BUS/Quantum Delft","","",""
"uuid:315bdd4b-84bb-4a9b-8f2d-831a6a13459e","http://resolver.tudelft.nl/uuid:315bdd4b-84bb-4a9b-8f2d-831a6a13459e","Needles and liver phantoms in interventional radiology: Design considerations","de Jong, T.L. (TU Delft Medical Instruments & Bio-Inspired Technology)","Dankelman, J. (promotor); van den Dobbelsteen, J.J. (promotor); Delft University of Technology (degree granting institution)","2019","Liver carcinoma is in the top five leading causes of cancer death worldwide. Patients often require radiologic interventions in which needles are inserted, for example when taking biopsies, accessing blood vessels or bile ducts, and ablating tumors. Accurate and precise needle placement in interventional radiology is important, but also challenging. Challenges include several factors, such as anatomical obstructions along the insertion path, patient motion, and unwanted needle bending upon insertion. Incorrect needle placement may prolong procedure time, increase radiation dose for the patient and may cause complications. Proposed approaches to improve needle placement in interventional radiology include, but are not limited to, steerable needles and liver phantoms. Although steerable needles are technically feasible to produce, these prototypes are often general-purpose. Currently, there is a lack of (analyzed) clinical and experimental data that provide insight into needle placement, and that would clarify the right design requirements for novel needles in interventional radiology. Another gap exists in the development of liver phantoms, which can be used in a validation set-up for novel needles and/or a training model for medical doctors. Current phantom development focusses mostly on medical imaging properties. However, matching needle-tissue interaction forces and simulating breathing motion are also crucial for a phantom to be of use in a realistic validation set-up. Therefore, the objectives of this thesis are to define relevant design considerations for novel needles, and to develop a high fidelity liver phantom that features respiratory motion and that mimics needle-tissue interaction forces upon insertion. Accomplishing this will improve and advance needle placement in interventional radiology.","","en","doctoral thesis","","978-94-6375-600-6","","","","","","","","","Medical Instruments & Bio-Inspired Technology","","",""
"uuid:4f4196f3-fadb-4170-b6d2-c0923dbd325a","http://resolver.tudelft.nl/uuid:4f4196f3-fadb-4170-b6d2-c0923dbd325a","Dynamical behavior of trampoline membranes","de Jong, M.H.J. (TU Delft QN/Groeblacher Lab; TU Delft Dynamics of Micro and Nano Systems)","Groeblacher, S. (promotor); Norte, R.A. (copromotor); Delft University of Technology (degree granting institution)","2022","This thesis comprises several experiments involving silicon nitride trampoline membranes. These membranes are excellent mechanical resonators and can be fabricated with desirable optical properties. Their dynamical behavior, particularly the interaction of their mechanical motion with light, is of interest for optomechanics and sensing applications. In the first experiment, I study the dissipation of trampoline membranes due to coupling to the substrate modes. It is known that the clamping of the substrate can affect the dissipation of its resonators, and this experiment provides a systematic investigation into this effect. The results show a clear reduction of mechanical Q-factor (increase of dissipation) when a resonator is resonant with a substrate mode. This highlights the design of the substrate modes for high-Q mechanical resonators. In the second experiment, I study the appearance of mechanical frequency combs in trampoline membranes. The interaction of a standing wave light field with the silicon nitride membrane through the dielectrophoretic force is similar to an optical trap. If the mechanical motion is sufficiently large, the periodicity of that force creates perfect integer multiple copies of the original motion frequency, which form a frequency comb. This makes it possible to generate mechanical frequency combs using a simple setup with little technical requirements. In the third experiment, I study the behavior of ringdown measurements involving near-degenerate modes. When both modes are within the detection bandwidth of the setup, their signal interferes and the ringdown displays ’ringing’. It is possible to extract the linear and non-linear parameters of both near-degenerate modes, and extract their relative coherence in the Brownian motion regime. This provides a characterization method for systems with near-degenerate mechanical modes. In the fourth experiment, I study the interaction of two trampoline membranes with a single optical cavity mode. The optical field couples the mechanical motion of the two membranes, but with a time delay based on the cavity lifetime. The associated phase-shift of the mechanical responses causes destructive interference, which leads to mechanical noise cancellation. This could be used to improve sensors suffering from mechanical thermal noise, and is important when studying optomechanical multi-resonator interactions.","Optomechanics; Dynamics; Microresonators; Mode coupling; Frequency combs; Noise cancellation","en","doctoral thesis","","9789085935438","","","","","","","","","QN/Groeblacher Lab","","",""
"uuid:ef90d088-f7ac-4767-a926-3b4bac9497e9","http://resolver.tudelft.nl/uuid:ef90d088-f7ac-4767-a926-3b4bac9497e9","Alkaliphilic Life: Adaptation strategies by Caldalkalibacillus thermarum","de Jong, S.I. (TU Delft BT/Environmental Biotechnology)","van Loosdrecht, Mark C.M. (promotor); McMillan, D.G.G. (copromotor); Delft University of Technology (degree granting institution)","2024","Alkaliphiles thrive in environments with a pH of 8.5 or above, while maintaining an internal pH closer to neutral. Thus, alkaliphilic microorganisms have a proton gradient inverted with respect to the normal orientation. Intuitively, this would nullify the potential to generate energy via respiration with regularly oriented respiratory chains that rely on proton-coupled ATP synthases. Yet, alkaliphilic respiratory chains are oriented traditionally and are actively used. The question therefore is how they are able to create conditions conducive to such behaviour. In addition, attempts to answer that question will hopefully also clarify how alkaliphiles acidify their cytoplasm with respect to the exterior milieu in the first place. This thesis details methods required to study these questions and provides some answers regarding alkaliphilic life. This thesis focuses on a single category of alkaliphiles: the low-salt gram positive alkaliphiles. These microbes have just a single membrane, the proteins therein, and a cell wall to generate conditions suitable for energy generation and other transport mechanisms. In short, it can be regarded as the most basic system to study an alkaline, or basic, problem....","Alkaliphile; Membrane; Genomics; Proteomics; Lipidomics","en","doctoral thesis","","978-94-6361-963-9","","","","","","","","","BT/Environmental Biotechnology","","",""
"uuid:a6514795-194f-49fd-937e-2bc61f9c371b","http://resolver.tudelft.nl/uuid:a6514795-194f-49fd-937e-2bc61f9c371b","Proeftochttoeslagen. Deel II","de Jong, H.R.","","1969","","hydrodynamics","","journal article","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:ab53f461-d039-46c5-85ca-330762ef2cb0","http://resolver.tudelft.nl/uuid:ab53f461-d039-46c5-85ca-330762ef2cb0","Thermal design based on surface temperature mapping","de Jong, E.C.W.; Ferreira, J.A.; Bauer, P.","","2005","","","en","journal article","IEEE","","","","","","","","","","","","",""
"uuid:c38fa1d4-5805-433f-9b07-5d79a02386c6","http://resolver.tudelft.nl/uuid:c38fa1d4-5805-433f-9b07-5d79a02386c6","Zeegangsgedrag van snelle schepen","de Jong, Pepijn","","2012","","hydrodynamics","","journal article","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:1087b040-d3fa-4931-b985-84e531cc899f","http://resolver.tudelft.nl/uuid:1087b040-d3fa-4931-b985-84e531cc899f","Hulpzeilvoortstuwing","de Jong, Marja; Struyk, Gijsbert; Vogels, Roderik; Voncken, Colin","","2012","","yachting","","journal article","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:6eb4bf7d-baeb-4cc1-a96c-bedea7753d0f","http://resolver.tudelft.nl/uuid:6eb4bf7d-baeb-4cc1-a96c-bedea7753d0f","A microcontroller-based self-calibration technique for a smart capacitive angular-position sensor","Li, X.; Meijer, G.C.M.; de Jong, G.W.","","1997","","","en","journal article","IEEE","","","","","","","","","","","","",""
"uuid:1bf61db6-9f3c-41fa-8566-47201730f8f7","http://resolver.tudelft.nl/uuid:1bf61db6-9f3c-41fa-8566-47201730f8f7","N.S.P. proeftochttoeslagen 1976","de Jong, H.R.","","1976","","hydrodynamics","","journal article","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:751d04fe-3a59-4f7a-92bb-5fe18c06335d","http://resolver.tudelft.nl/uuid:751d04fe-3a59-4f7a-92bb-5fe18c06335d","The influence of electric-field bending on the nonlinearity of capacitive sensors","Li, X.; de Jong, G.; Meijer, G.C.M.","","2000","","","en","journal article","IEEE","","","","","","","","","","","","",""
"uuid:3bf0b142-7fb6-4359-aa42-fea8e6dd7b36","http://resolver.tudelft.nl/uuid:3bf0b142-7fb6-4359-aa42-fea8e6dd7b36","The application of the capacitor's physics to optimize capacitive angular-position sensors","de Jong, G.; Meijer, G.C.M.","","1997","","","en","journal article","IEEE","","","","","","","","","","","","",""
"uuid:9861c24e-4239-4b39-a9e5-5a0a1d4b2a50","http://resolver.tudelft.nl/uuid:9861c24e-4239-4b39-a9e5-5a0a1d4b2a50","An accurate low-cost capacitive absolute angular-position sensor with a full-circle range","Meijer, G.C.M.; de Jong, G.W.; Spronck, J.W.","","1996","","","en","journal article","IEEE","","","","","","","","","","","","",""
"uuid:30683878-6b86-4342-9d16-1e5b58e5afb3","http://resolver.tudelft.nl/uuid:30683878-6b86-4342-9d16-1e5b58e5afb3","Proeftochttoeslagen op de vermogenskrommen geëxtrapoleerd volgens de methode en met de wrijvingscoëfficiënten van Froude","de Jong, H.R.","","1965","","hydrodynamics","","journal article","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:431c07af-da43-47a7-b9f1-377727611f7d","http://resolver.tudelft.nl/uuid:431c07af-da43-47a7-b9f1-377727611f7d","Hulpzeilvoortstuwing","de Jong, M.; Struyk, G.; Vogels, R.; Vonken, C.","","2013","","yachting","","journal article","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:73232da4-1497-4838-8f1f-d5441ee31784","http://resolver.tudelft.nl/uuid:73232da4-1497-4838-8f1f-d5441ee31784","6-DOF forced ocillation tests for the evaluation of nonlinearities in the superposition of ship motions","de Jong, Pepijn; Keuning, Jan Alexander","","2006","","hydrodynamics","","journal article","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:6dc59f03-b8ba-4183-a4b5-33d77df978e0","http://resolver.tudelft.nl/uuid:6dc59f03-b8ba-4183-a4b5-33d77df978e0","Absolute voltage amplification using dynamic feedback control","de Jong, P.C.; Meijer, G.C.M.","","1997","","","en","journal article","IEEE","","","","","","","","","","","","",""
"uuid:02211a75-f067-4955-a2ad-f111f5078ed8","http://resolver.tudelft.nl/uuid:02211a75-f067-4955-a2ad-f111f5078ed8","The rigging of the clipper ""Stad Amsterdam""","de Jong, Marijke","","2000","","ship design production and operation","","journal article","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:c47e2bee-bfd1-4010-8a1a-6ac8234f4956","http://resolver.tudelft.nl/uuid:c47e2bee-bfd1-4010-8a1a-6ac8234f4956","On the influence of choice of generator lines on the optimum efficiency of screw propellers","de Jong, K.; Sparenberg, J.A.","","1990","","resistance & propulsion","","journal article","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:d26c87a1-e79f-49a4-8e37-c1a919691baf","http://resolver.tudelft.nl/uuid:d26c87a1-e79f-49a4-8e37-c1a919691baf","A sensitive optical micro-machined ultrasound sensor (OMUS) based on a silicon photonic ring resonator on an acoustical membrane","Leinders, S.M.; Westerveld, W.J.; Pozo, J.; Neer, P.L.M.J.; Snyder, B.; O'Brien, P.; Urbach, H.P.; de Jong, N.; Verweij, M.D.","","2015","With the increasing use of ultrasonography, especially in medical imaging, novel fabrication techniques together with novel sensor designs are needed to meet the requirements for future applications like three-dimensional intercardiac and intravascular imaging. These applications require arrays of many small elements to selectively record the sound waves coming from a certain direction. Here we present proof of concept of an optical micro-machined ultrasound sensor (OMUS) fabricated with a semi-industrial CMOS fabrication line. The sensor is based on integrated photonics, which allows for elements with small spatial footprint. We demonstrate that the first prototype is already capable of detecting pressures of 0.4?Pa, which matches the performance of the state of the art piezo-electric transducers while having a 65 times smaller spatial footprint. The sensor is compatible with MRI due to the lack of electronical wiring. Another important benefit of the use of integrated photonics is the easy interrogation of an array of elements. Hence, in future designs only two optical fibers are needed to interrogate an entire array, which minimizes the amount of connections of smart catheters. The demonstrated OMUS has potential applications in medical ultrasound imaging, non destructive testing as well as in flow sensing.","","en","journal article","Nature Publishing Group","","","","","","","","Applied Sciences","ImPhys/Imaging Physics","","","",""
"uuid:3c8a2950-532f-41c5-96c7-131ba8f58e07","http://resolver.tudelft.nl/uuid:3c8a2950-532f-41c5-96c7-131ba8f58e07","The hydrodynamic coefficients of two parallel identical cylinders oscillating in the free surface","de Jong, Bart","","1970","","hydrodynamics","","journal article","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:4e9cd348-40eb-4023-81b0-790d26fd1679","http://resolver.tudelft.nl/uuid:4e9cd348-40eb-4023-81b0-790d26fd1679","A high-temperature electronic system for pressure-transducers","de Jong, P.C.; Meijer, G.C.M.","","2000","","","en","journal article","IEEE","","","","","","","","","","","","",""
"uuid:8cd015c8-f8e6-4455-918c-c266f251d0e9","http://resolver.tudelft.nl/uuid:8cd015c8-f8e6-4455-918c-c266f251d0e9","Pleasure yacht of passenger ship? Designing a luxury superyacht in compliance with the passenger yacht code","de Jong, D.","","2014","","ship design production and operation","","journal article","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","","","",""
"uuid:d0964346-e0ff-4384-aac4-c476a93a63a2","http://resolver.tudelft.nl/uuid:d0964346-e0ff-4384-aac4-c476a93a63a2","Microscopic dynamics in liquid lithium","Torcini, A.; Balucani, U.; de Jong, P.H.K.; Verkerk, P.","","1995","","","en","journal article","American Physical Society","","","","","","","","","","","","",""
"uuid:746ec42b-21d7-4805-a7fb-e84d507e468b","http://resolver.tudelft.nl/uuid:746ec42b-21d7-4805-a7fb-e84d507e468b","Zero-dimensional states and single electron charging in quantum dots","Johnson, A.T.; Kouwenhoven, L.P.; de Jong, W.; van der Vaart, N.C.; Harmans, C.J.P.M.; Foxon, C.T.","","1992","","","en","journal article","American Physical Society","","","","","","","","","","","","",""
"uuid:34d02c7e-66f4-476f-ade7-09ef2d7e4a17","http://resolver.tudelft.nl/uuid:34d02c7e-66f4-476f-ade7-09ef2d7e4a17","Control of industrial crystallizers","Jager, J.; Kramer, H.J.M.; de Jong, E.J.; de Wolf, S.; Bosgra, O.H.; Boxman, A.; Merkus, H.G.; Scarlett, B.","","1992","","","en","journal article","Elsevier","","","","","","","","","","","","",""
"uuid:bb1671fd-9bde-4ad0-a562-83171fd409b6","http://resolver.tudelft.nl/uuid:bb1671fd-9bde-4ad0-a562-83171fd409b6","Ruimte voor integrale toegankelijkheid van gebouwen","van der Voordt, D.J.M.; de Jong, G.E.","","1994","","","nl","journal article","","","","","","","","","Architecture and The Built Environment","","","","",""
"uuid:f0248acb-b524-4e1b-987b-50863573663c","http://resolver.tudelft.nl/uuid:f0248acb-b524-4e1b-987b-50863573663c","Risicomanagement bij huisvestingsprojecten: Innovaties voor een succesvolle implementatie","Gehner, E.; de Jong, I.","","2011","In de praktijk van infrastructuurprojecten wordt risicomanagement standaard toegepast bij projecten. Rijkswaterstaat heeft als professionele opdrachtgever ongeveer acht jaar geleden risicomanagement geïmplementeerd en onderdeel gemaakt van iedere uitvoerende projectorganisatie. Bij huisvestingsprojecten ligt dit anders. Opdrachtgevers van dergelijke projecten hebben slechts een enkele keer te maken met een dergelijk complex project. De eigenaar-gebruiker kan zich moeilijk verlaten op ervaring en intuïtie en dus lijkt risicomanagement een vanzelfsprekende aangelegenheid. Niets is minder waar.","","nl","journal article","Weka","","","","","","","","Architecture","Real Estate and Housing","","","",""
"uuid:659ab6cf-28a1-4279-8684-98e1d85199cc","http://resolver.tudelft.nl/uuid:659ab6cf-28a1-4279-8684-98e1d85199cc","Strategic Use of Analytical Information in Transport Planning in China: How Is It Different from Western Democracies?","Mu, R. (Dalian University of Technology); Mouter, N. (TU Delft Transport and Logistics); de Jong, W.M. (TU Delft Organisation & Governance)","","2016","Theory on the strategic use of knowledge in planning large infrastructure projects is comparatively well-developed in the fields of public policy and urban/transport planning for Western democracies. But how policymakers make use of knowledge and what position policy analysts hold in non-Western countries still remains largely unknown territory in the literature. This article begins to explore this topic by studying two urban transport projects in the Chinese city of Dalian. Based on empirical evidence, the article concludes with a number of preliminary but notable differences between Western countries and China in terms of the administrative mechanisms underlying the strategic use of knowledge in policymaking. We found that Chinese institutional incentives with regard to cadre evaluation and promotion channels largely constitute the motivation of politicians to use knowledge strategically. Additionally, the wider social and administrative cultures in China, including a command-and-control tradition and a high level of power distance create a basis for the strategic use of information as well as the manipulation of analytical data.","China; comparative policy analysis; Dalian; strategic use of knowledge; transport planning","en","journal article","","","","","","Accepted Author Manuscript","","2017-10-20","","","Transport and Logistics","","",""
"uuid:19954de3-fa21-4096-8616-1bebb81fcc48","http://resolver.tudelft.nl/uuid:19954de3-fa21-4096-8616-1bebb81fcc48","Probing the Nuclear Spin-Lattice Relaxation Time at the Nanoscale","Wagenaar, J.J.T. (Universiteit Leiden); Den Haan, A.M.J. (Universiteit Leiden); de Voogd, J.M. (Universiteit Leiden); Bossoni, L. (Universiteit Leiden); de Jong, T.A. (Universiteit Leiden); de Wit, M. (Universiteit Leiden); Bastiaans, K.M. (Universiteit Leiden); Thoen, David (TU Delft Tera-Hertz Sensing); Endo, A. (TU Delft QN/Quantum Nanoscience; TU Delft Tera-Hertz Sensing; Kavli institute of nanoscience Delft); Klapwijk, T.M. (TU Delft QN/Klapwijk Lab; Moscow State Pedagogical University; Kavli institute of nanoscience Delft); Zaanen, J. (Universiteit Leiden); Oosterkamp, TH (Universiteit Leiden)","","2016","Nuclear spin-lattice relaxation times are measured on copper using magnetic-resonance force microscopy performed at temperatures down to 42 mK. The low temperature is verified by comparison with the Korringa relation. Measuring spin-lattice relaxation times locally at very low temperatures opens up the possibility to measure the magnetic properties of inhomogeneous electron systems realized in oxide interfaces, topological insulators, and other strongly correlated electron systems such as high-Tc superconductors.","","en","journal article","","","","","","","","","","QN/Quantum Nanoscience","Tera-Hertz Sensing","","",""
"uuid:a3e3ffcb-d988-4fec-8df9-44511d3a9160","http://resolver.tudelft.nl/uuid:a3e3ffcb-d988-4fec-8df9-44511d3a9160","Triamcinolone acetonide activates an anti-inflammatory and folate receptor–positive macrophage that prevents osteophytosis in vivo","Siebelt, M (Erasmus MC); Korthagen, NM (University Medical Center Utrecht); Wei, W. (Erasmus MC); Groen, H (Erasmus MC); Bastiaansen-Jenniskens, YM (Erasmus MC); Müller, C (ETH Zürich); Waarsing, JH (Erasmus MC); de Jong, M (University Medical Center Utrecht; Erasmus MC); Weinans, Harrie (TU Delft Biomaterials & Tissue Biomechanics; University Medical Center Utrecht)","","2015","","","en","journal article","","","","","","","","","","","Biomaterials & Tissue Biomechanics","","",""
"uuid:dd9ec35f-99b5-4238-ab79-5cb3db00ef49","http://resolver.tudelft.nl/uuid:dd9ec35f-99b5-4238-ab79-5cb3db00ef49","Size and Promoter Effects on Stability of Carbon-Nanofiber-Supported Iron-Based Fischer-Tropsch Catalysts","Xie, Jingxiu (Universiteit Utrecht); Torres Galvis, Hirsa M. (Universiteit Utrecht); Koeken, Ard C J (Dow); Kirilin, Alexey (Dow); Dugulan, A.I. (TU Delft RST/Fundamental Aspects of Materials and Energy); Ruitenbeek, Matthijs (Dow); de Jong, Krijn P. (Universiteit Utrecht)","","2016","The Fischer−Tropsch Synthesis converts synthesis gas from alternative carbon resources, including natural gas, coal, and biomass, to hydrocarbons used as fuels or chemicals. In particular, iron-based catalysts at elevated temperatures favor the selective production of C2−C4 olefins, which are important building blocks for the chemical industry. Bulk iron catalysts (with promoters) were conventionally used, but these deactivate due to either phase transformation or carbon deposition resulting in disintegration of the catalyst particles. For supported iron catalysts, iron particle growth may result in loss of catalytic activity over time. In this work, the effects of promoters and particle size on the stability of supported iron nanoparticles (initial sizes of 3−9 nm) were investigated at industrially relevant conditions (340 °C, 20 bar, H2/CO = 1). Upon addition of sodium and sulfur promoters to iron nanoparticles supported on carbon nanofibers, initial catalytic activities were high, but substantial deactivation was observed over a period of 100 h. In situ Mössbauer spectroscopy revealed that after 20 h time-on-stream, promoted catalysts attained 100% carbidization, whereas for unpromoted catalysts, this was around 25%. In situ carbon deposition studies were carried out using a tapered element oscillating microbalance (TEOM). No carbon laydown was detected for the unpromoted catalysts, whereas for promoted catalysts, carbon deposition occurred mainly over the first 4 h and thus did not play a pivotal role in deactivation over 100 h. Instead, the loss of catalytic activity coincided with the increase in Fe particle size to 20−50 nm, thereby supporting the proposal that the loss of active Fe surface area was the main cause of deactivation.","Fischer−Tropsch; FTO; iron; lower olefins; synthesis gas; stability; sintering","en","journal article","","","","","","","","","","","RST/Fundamental Aspects of Materials and Energy","","",""
"uuid:31bce0f8-c532-4264-8caf-155f4eda537d","http://resolver.tudelft.nl/uuid:31bce0f8-c532-4264-8caf-155f4eda537d","Development of a new therapeutic technique to direct stem cells to the infarcted heart using targeted microbubbles: StemBells","Woudstra, L. (Amsterdam UMC); Krijnen, PAJ (Amsterdam UMC); Bogaards, SJP (Amsterdam UMC); Meinster, E (Amsterdam UMC); Emmens, RW (Amsterdam UMC; Erasmus MC); Kokhuis, TJA (Interuniversity Cardiology Institute of the Netherlands (ICIN)); Bollen, IAE (Amsterdam UMC); Baltzer, H (Amsterdam UMC); Baart, SMT (Amsterdam UMC); Parbhudayal, R (Amsterdam UMC); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC; Interuniversity Cardiology Institute of the Netherlands (ICIN)); Helder, MN (Amsterdam UMC); Hinsbergh, V.W.M. (Amsterdam UMC); Musters, RJP (Amsterdam UMC); Kamp, O. (Interuniversity Cardiology Institute of the Netherlands (ICIN); Amsterdam UMC); Niessen, H.W.M. (Amsterdam UMC); van Dijk, A. (Amsterdam UMC); Juffermans, LJ (Amsterdam UMC; Interuniversity Cardiology Institute of the Netherlands (ICIN))","","2016","Successful stem cell therapy after acute myocardial infarction (AMI) is hindered by lack of engraftment of sufficient stem cells at the site of injury. We designed a novel technique to overcome this problem by assembling stem cell-microbubble complexes, named 'StemBells'. StemBells were assembled through binding of dual-targeted microbubbles (~3μm) to adipose-derived stem cells (ASCs) via a CD90 antibody. StemBells were targeted to the infarct area via an ICAM-1 antibody on the microbubbles. StemBells were characterized microscopically and by flow cytometry. The effect of ultrasound on directing StemBells towards the vessel wall was demonstrated in an in vitro flow model. In a rat AMI-reperfusion model, StemBells or ASCs were injected one week post-infarction. A pilot study demonstrated feasibility of intravenous StemBell injection, resulting in localization in ICAM-1-positive infarct area three hours post-injection. In a functional study five weeks after injection of StemBells cardiac function was significantly improved compared with controls, as monitored by 2D-echocardiography. This functional improvement neither coincided with a reduction in infarct size as determined by histochemical analysis, nor with a change in anti- and pro-inflammatory macrophages. In conclusion, the StemBell technique is a novel and feasible method, able to improve cardiac function post-AMI in rats.","Acoustic radiation force; Acute myocardial infarction; Adipose tissue-derived stem cells; Microbubbles; StemBells; Targeting","en","journal article","","","","","","","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:dc1c976a-b2f0-4335-9070-527216edfef7","http://resolver.tudelft.nl/uuid:dc1c976a-b2f0-4335-9070-527216edfef7","Financing Sino-Singapore Tianjin Eco-City: What lessons can be drawn for other large-scale sustainable city-projects?","Zhan, C. (TU Delft Organisation & Governance); de Jong, W.M. (TU Delft Organisation & Governance; Fudan University)","","2017","Sino-Singapore Tianjin Eco-City (SSTEC) is currently the best-known and arguably the most successful large-scale sustainable new town development project in China; as such, experiences gathered there are of significant importance for the development of other eco-cities in China and elsewhere. This article focuses on a thus far relatively understudied aspect of SSTEC, the financial vehicles used to fund SSTEC. The authors find that highly structured and intense collaboration at the national level between China and Singapore plays a catalytic role in attracting many other players to the project by giving them confidence that it is too big to fail. It encourages various preferential policies from lower governmental bodies, broad involvement of the private sector, a market-based operation model and the issuing of bonds in Singapore, which all contribute significantly to Tianjin eco-city's financial viability. The broad involvement of the private sector relieves part of the financial burden from local governments, while the bonds issued in international markets lower the interest rate for master developers. However, the Sino-Singaporean collaboration at the national level is far less likely to be replicated to other eco-cities, since this requires an enormous willingness on the part of other countries to invest manpower, money, and other resources into the construction of eco-cities in China.","Bonds; China; Financial arrangements; Organizational arrangements; Tianjin Eco-City; OA-Fund TU Delft","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:73276743-0520-4d3f-92fa-befcfc0a3bcf","http://resolver.tudelft.nl/uuid:73276743-0520-4d3f-92fa-befcfc0a3bcf","The influence of tip shape on bending force during needle insertion","van de Berg, N.J. (TU Delft Medical Instruments & Bio-Inspired Technology); de Jong, T.L. (TU Delft Medical Instruments & Bio-Inspired Technology); van Gerwen, D.J. (TU Delft Medical Instruments & Bio-Inspired Technology); Dankelman, J. (TU Delft Medical Instruments & Bio-Inspired Technology); van den Dobbelsteen, J.J. (TU Delft Medical Instruments & Bio-Inspired Technology)","","2017","Steering of needles involves the planning and timely modifying of instrument-tissue force interactions to allow for controlled deflections during the insertion in tissue. In this work, the effect of tip shape on these forces was studied using 10 mm diameter needle tips. Six different tips were selected, including beveled and conical versions, with or without pre-bend or pre-curve. A six-degree-of-freedom force/torque sensor measured the loads during indentations in tissue simulants. The increased insertion (axial) and bending (radial) forces with insertion depth-the force-displacement slopes-were analyzed. Results showed that the ratio between radial and axial forces was not always proportional. This means that the tip load does not have a constant orientation, as is often assumed in mechanics-based steering models. For all tip types, the tip-load assumed a more radial orientation with increased axial load. This effect was larger for straight tips than for pre-bent or pre-curved tips. In addition, the force-displacement slopes were consistently higher for (1) increased tip angles, and for (2) beveled tips compared to conical tips. Needles with a bent or curved tip allow for an increased bending force and a decreased variability of the tip load vector orientation.","Biomedical engineering; Scientific data","en","journal article","","","","","","","","","","","Medical Instruments & Bio-Inspired Technology","","",""
"uuid:7d321682-45dd-442d-a8ea-2d61d9dab8df","http://resolver.tudelft.nl/uuid:7d321682-45dd-442d-a8ea-2d61d9dab8df","Dataset on force measurements of needle insertions into two ex-vivo human livers","de Jong, T.L. (TU Delft Medical Instruments & Bio-Inspired Technology); Dankelman, J. (TU Delft Medical Instruments & Bio-Inspired Technology); van den Dobbelsteen, J.J. (TU Delft Medical Instruments & Bio-Inspired Technology)","","2017","A needle-tissue interaction experiment has been carried out, by inserting the inner needle of a trocar needle into two ex-vivo human livers. The dataset contains the forces that act on the needle during insertion and retraction into the livers. In addition, a MATLAB code file is included that provides base-level analysis of the data and generates force-position diagrams of the needle insertions. The dataset is available on Mendeley Data (do1i:10.17632/94s7xd9mzt.2), and is made publicly available to enable other researchers to use it for their own research purposes. For further interpretation and discussion of the data, one is referred to the associated research article entitled “PVA matches human liver in needle-tissue interaction” de Jong et al., 2017.","","en","journal article","","","","","","","","","","","Medical Instruments & Bio-Inspired Technology","","",""
"uuid:21f5a09a-bcca-441a-a023-22aa7fa5f904","http://resolver.tudelft.nl/uuid:21f5a09a-bcca-441a-a023-22aa7fa5f904","Economic City Branding in China: the Multi-Level Governance of Municipal Self-Promotion in the Greater Pearl River Delta","Lu, H. (TU Delft Organisation & Governance); de Jong, W.M. (TU Delft Organisation & Governance; Fudan University; Erasmus Universiteit Rotterdam); Chen, Y. (TU Delft Urban Development Management)","","2017","In the urban development policy in China, city brands play an important role in setting targets for Chinese cities. These economic city brands, however, are not produced in an institutional vacuum: they are embedded in the visions national, provincial and municipal governments have for these cities, i.e., on multi-level governance. In this paper, a data-intense analysis of economic city branding practices has been conducted in the Greater Pearl River Delta, taking into account national, provincial and municipal documents in socio-economic, urban and land use planning. Evidence of economic and ecological initiatives through branding at the level of symbolic urban projects, such as new towns, has also been examined. It transpires that Hong Kong, Macau, Guangzhou and Shenzhen have adopted more sophisticated economic brand identities than the others and the reflection of brand-related targets from their actual projects is also more credible. While China’s national plans focus primarily on Hong Kong and Macau, provincial documents place more emphasis on the wealthier cities on the mainland (Shenzhen and Guangzhou). The other cities attract less attention and have more freedom to adopt economic city brands, but their efforts to live up to their promise are quite limited due to their weak financial position.","economic city branding; multi-level governance; city profile; China; new towns; OA-Fund TU Delft","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:47632dfc-4c6a-4860-8a7b-d803d5bc6395","http://resolver.tudelft.nl/uuid:47632dfc-4c6a-4860-8a7b-d803d5bc6395","Combined optical sizing and acoustical characterization of single freely-floating microbubbles","Luan, Ying (Erasmus MC); Renaud, Guillaume (Erasmus MC; UPMC-Sorbonne Universités & CNRS); Raymond, Jason L. (Erasmus MC); Segers, Tim (University of Twente); Lajoinie, Guillaume (University of Twente); Beurskens, Robert (Erasmus MC); Mastik, Frits (Erasmus MC); Kokhuis, Tom J A (Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Versluis, Michel (University of Twente); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC)","","2016","In this study we present a combined optical sizing and acoustical characterization technique for the study of the dynamics of single freely-floating ultrasound contrast agent microbubbles exposed to long burst ultrasound excitations up to the milliseconds range. A co-axial flow device was used to position individual microbubbles on a streamline within the confocal region of three ultrasound transducers and a high-resolution microscope objective. Bright-field images of microbubbles passing through the confocal region were captured using a high-speed camera synchronized to the acoustical data acquisition to assess the microbubble response to a 1-MHz ultrasound burst. Nonlinear bubble vibrations were identified at a driving pressure as low as 50 kPa. The results demonstrate good agreement with numerical simulations based on the shell-buckling model proposed by Marmottant et al. [J. Acoust. Soc. Am. 118, 3499-3505 (2005)]. The system demonstrates the potential for a high-throughput in vitro characterization of individual microbubbles.","Ultranonography; Bubble dynamics; Nonlinear dynamics; Vibration testing; Cameras","en","journal article","","","","","","","","2017-12-07","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:909d636f-5381-49f4-8c11-a404d3d58163","http://resolver.tudelft.nl/uuid:909d636f-5381-49f4-8c11-a404d3d58163","Time and Energy Management During Approach: A Human-in-the-Loop Study","de Jong, P.M.A. (TU Delft Control & Simulation); Bussink, F. J L (Royal Netherlands Aerospace Centre NLR); Verhoeven, RPM (Royal Netherlands Aerospace Centre NLR); de Gelder, N (Royal Netherlands Aerospace Centre NLR); van Paassen, M.M. (TU Delft Control & Simulation); Mulder, Max (TU Delft Control & Operations)","","2017","","","en","journal article","","","","","","","","","","Control & Operations","Control & Simulation","","",""
"uuid:57b32f08-2abd-4991-ab0b-586a1a394215","http://resolver.tudelft.nl/uuid:57b32f08-2abd-4991-ab0b-586a1a394215","Economic transformation in the Beijing-Tianjin-Hebei region: Is it undergoing the Environmental Kuznets Curve?","Xiong, Lichun (Beijing Forestry University); Yu, Chang (Beijing Forestry University); de Jong, W.M. (TU Delft Organisation & Governance; Fudan University; Erasmus Universiteit Rotterdam); Wang, Fengting (China Agricultural University); Cheng, Baodong (Beijing Forestry University)","","2017","The Beijing-Tianjin-Hebei Region Integration Plan is one of the most important national strategies in China promoting regional economic development. The environmental problems in this region, however, especially air pollution and contaminated groundwater, have enormous influence on the people's health while also causing economic loss. Therefore, this study aims to analyze the pattern of its environmental and economic development. Panel data in the period 2004-2014 are used to establish an advanced model of the Environmental Kuznets Curve. The results indicate that the economic growth and environmental pollution of Beijing-Tianjin-Hebei region do not completely meet the Environment Kuznets Curve assumptions. The discharge volume of industrial wastewater and economic growth reflect a wave-type relation. The sulfur dioxide discharge volume and economic growth reflect a U-shaped relation; the generated volume of industrial solid wastes and economic growth reflect a reversed N-shaped relation, which is in accordance with the Environmental Kuznets Curve characteristics at the second inflection point. The variables added value of the secondary industry, population size and raw coal consumption volume have a significant positive influence on the discharge of various environmental pollutants in Beijing-Tianjin-Hebei region. The analysis provides policy recommendations for the government to develop regional economic and environmental protection policies.","Beijing-Tianjin-Hebei region; Economic growth; Environmental Kuznets curve; Environmental pollution","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:c2e78f4b-da86-41a2-8f60-79cf11d43ffe","http://resolver.tudelft.nl/uuid:c2e78f4b-da86-41a2-8f60-79cf11d43ffe","Pilot scale steam-oxygen CFB gasification of commercial torrefied wood pellets. The effect of torrefaction on the gasification performance","Di Marcello, M. (TU Delft Energy Technology); Tsalidis, G.A. (TU Delft Large Scale Energy Storage); Spinelli, G. (University of Teramo); de Jong, W. (TU Delft Large Scale Energy Storage; Rijksuniversiteit Groningen); Kiel, J.H.A. (TU Delft Process and Energy; ECN Solar Energy)","","2017","Torrefaction is a promising biomass upgrading technology as it makes biomass more coal alike and offers benefits in logistics and handling operations. Gasification is an attractive thermochemical conversion technology due to its flexibility in the product gas end-uses. Therefore, it is valuable to investigate whether additional benefits are foreseen when torrefaction is coupled with gasification. Therefore, two commercial torrefied wood fuels and their parent materials are gasified at 800–850 °C under atmospheric steam-oxygen circulating fluidized bed gasification conditions and magnesite as bed material. The torrefied feedstocks consisted of wood residues torrefied by Topell at 250 °C (Topell black), and mixed wood and wood residues torrefied by Torrcoal at 300 °C (Torrcoal black). The gasification results show that torrefaction resulted in an increased gas quality, as it yielded higher H2 and CO contents, a decrease of the CO2 content, increased gas yield and a significant decrease of the total tar content for both feedstocks. For the Torrcoal samples, torrefaction resulted in a decrease in the carbon conversion efficiency (CCE). In addition, the cold gas efficiency (CGE) remained approximately the same due to the increase in the H2 and CO contents. The Topell samples showed an increase in the CCE and CGE upon torrefaction, but this could be attributed to a significant grinding in the screw feeder. It is generally concluded that both torrefied fuels may offer benefits as a feedstock for steam-oxygen blown circulating fluidized bed gasification, in particular in terms of gas quality and yield.","Circulating fluidized bed; Gasification; Magnesite; Tar; Torrefaction; Wood","en","journal article","","","","","","","","","","Process and Energy","Energy Technology","","",""
"uuid:35a52eb0-1c02-4cea-be05-9b853d8ce42b","http://resolver.tudelft.nl/uuid:35a52eb0-1c02-4cea-be05-9b853d8ce42b","An LCA-based evaluation of biomass to transportation fuel production and utilization pathways in a large port’s context","Tsalidis, G.A. (TU Delft Large Scale Energy Storage); Discha, F.E. (TU Delft Delft Energy Initiative); Korevaar, G. (TU Delft Energie and Industrie); Haije, W.G. (TU Delft Large Scale Energy Storage); de Jong, W. (TU Delft Large Scale Energy Storage; Rijksuniversiteit Groningen); Kiel, J.H.A. (TU Delft Energy Technology; ECN, Petten)","","2017","This study evaluates whether a transition of large ports facilities to biofuel production for mobility improves the environmental performance and satisfies the renewable energy directive (RED) and it is the first LCA study that considers biofuel production from torrefied wood. The systems studied are wood, torrefied wood, and straw pellets circulating fluidized bed gasification for H2, synthetic natural gas, or Fischer–Tropsch (FT) diesel production and use. These systems are evaluated for their global warming, acidification, eutrophication and particulate matter potentials, as well as, for their aggregated environmental performance. The effects of the electricity mix selection and ecoinvent database’s economic allocation are also analyzed. All biomass systems result in a better aggregated environmental performance and benefits for the global warming potential. However, regarding the acidification, particulate matter, and eutrophication potentials, most biomass systems are inferior to the reference systems. Switching to a zero-emission electricity mix offers benefits for all the biomass and fossil-H2 systems and researchers should use databases cautiously. The bio-H2 and FT diesel of wood-based systems show the best environmental performance and satisfy the current and future RED targets. On one hand, the bio-H2 systems result in the largest benefits regarding the global warming potential, and on the other hand, both wood-based FT diesel systems offer overall benefits which concern not only the sustainable target of CO2 emissions reduction, but also the air quality improvement of the broader area as well.","Gasification; Life cycle assessment; Straw; Torrefaction; Transportation fuel; Wood","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:3d2f11ed-294e-40d9-9ed6-a102967dd402","http://resolver.tudelft.nl/uuid:3d2f11ed-294e-40d9-9ed6-a102967dd402","Laser-driven resonance of dye-doped oil-coated microbubbles: Experimental study","Lajoinie, Guillaume (University of Twente); Lee, Jeong Yu (University of Oxford); Owen, Joshua (University of Oxford); Kruizinga, P. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Van Soest, Gijs (Erasmus MC); Stride, Eleanor (University of Oxford); Versluis, Michel (University of Twente)","","2017","Photoacoustic (PA) imaging offers several attractive features as a biomedical imaging modality, including excellent spatial resolution and functional information such as tissue oxygenation. A key limitation, however, is the contrast to noise ratio that can be obtained from tissue depths greater than 1-2 mm. Microbubbles coated with an optically absorbing shell have been proposed as a possible contrast agent for PA imaging, offering greater signal amplification and improved biocompatibility compared to metallic nanoparticles. A theoretical description of the dynamics of a coated microbubble subject to laser irradiation has been developed previously. The aim of this study was to test the predictions of the model. Two different types of oil-coated microbubbles were fabricated and then exposed to both pulsed and continuous wave (CW) laser irradiation. Their response was characterized using ultra high-speed imaging. Although there was considerable variability across the population, good agreement was found between the experimental results and theoretical predictions in terms of the frequency and amplitude of microbubble oscillation following pulsed excitation. Under CW irradiation, highly nonlinear behavior was observed which may be of considerable interest for developing different PA imaging techniques with greatly improved contrast enhancement.","Lasers; Microbubbles; Acoustic signal processing; Medical imaging; Acoustic transducers","en","journal article","","","","","","","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:1893cabe-ba19-4ed6-956a-1555fea65709","http://resolver.tudelft.nl/uuid:1893cabe-ba19-4ed6-956a-1555fea65709","Laser-driven resonance of dye-doped oil-coated microbubbles: A theoretical and numerical study","Lajoinie, Guillaume (University of Twente); Linnartz, Erik (University of Twente); Kruizinga, P. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Stride, Eleanor (University of Oxford); Van Soest, Gijs (Erasmus MC); Versluis, Michel (University of Twente)","","2017","Microbubbles are used to enhance the contrast in ultrasound imaging. When coated with an optically absorbing material, these bubbles can also provide contrast in photoacoustic imaging. This multimodal aspect is of pronounced interest to the field of medical imaging. The aim of this paper is to provide a theoretical framework to describe the physical phenomena underlying the photoacoustic response. This article presents a model for a spherical gas microbubble suspended in an aqueous environment and coated with an oil layer containing an optically absorbing dye. The model includes heat transfer between the gas core and the surrounding liquids. This framework is suitable for the investigation of both continuous wave and pulsed laser excitation. This work utilizes a combination of finite difference simulations and numerical integration to determine the dependancy on the physical properties, including composition and thickness of the oil layer on the microbubble response. A normalization scheme for a linearized version of the model was derived to facilitate comparison with experimental measurements. The results show that viscosity and thickness of the oil layer determine whether or not microbubble resonance can be excited. This work also examines the use of non-sinusoidal excitation to promote harmonic imaging techniques to further improve the imaging sensitivity.","Viscosity; Bubble dynamics; Ultrasonography; Photoacoustic imaging; Laser theory","en","journal article","","","","","","","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:19f8c29d-20f8-4790-8a6e-6f8e715ed6a5","http://resolver.tudelft.nl/uuid:19f8c29d-20f8-4790-8a6e-6f8e715ed6a5","Cardiac Shear Wave Velocity Detection in the Porcine Heart","Vos, H.J. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); van Dalen, Bas M. (Erasmus MC); Heinonen, Ilkka (Erasmus MC; University of Turku); Bosch, Johan G. (Erasmus MC); Sorop, Oana (Erasmus MC); Duncker, Dirk J. (Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC; Netherlands Heart Institute; Chinese Academy of Sciences); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC; University of Turku)","","2017","Cardiac muscle stiffness can potentially be estimated non-invasively with shear wave elastography. Shear waves are present on the septal wall after mitral and aortic valve closure, thus providing an opportunity to assess stiffness in early systole and early diastole. We report on the shear wave recordings of 22 minipigs with high-frame-rate echocardiography. The waves were captured with 4000 frames/s using a programmable commercial ultrasound machine. The wave pattern was extracted from the data through a local tissue velocity estimator based on one-lag autocorrelation. The wave propagation velocity was determined with a normalized Radon transform, resulting in median wave propagation velocities of 2.2 m/s after mitral valve closure and 4.2 m/s after aortic valve closure. Overall the velocities ranged between 0.8 and 6.3 m/s in a 95% confidence interval. By dispersion analysis we found that the propagation velocity only mildly increased with shear wave frequency.","Echocardiography; High-frame-rate imaging; Shear wave elastography; Stiffness measurements; Valve closure","en","journal article","","","","","","","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:9c9a2153-0f21-4aaf-bcb4-e2a137723486","http://resolver.tudelft.nl/uuid:9c9a2153-0f21-4aaf-bcb4-e2a137723486","Seeing the People’s Republic of China through the Eyes of Montesquieu: Why Sino-European Collaboration on Eco City Development Suffers from European Misinterpretations of “Good Governance”","de Jong, W.M. (TU Delft Organisation & Governance; Fudan University; Erasmus Universiteit Rotterdam); Stout, H. (Erasmus Universiteit Rotterdam); Sun, L. (University of Leeds)","","2017","China faces a number of impressive challenges in dealing with climate change: rising energy use, growing emission levels of greenhouse gases, dangerous levels of air pollution over cities and low resilience against flood and drought. Sustainable urbanization has been adopted as a keyword in handling these challenges. The Chinese central government has undertaken a variety of measures, including the launch of large Sino-European programs to learn from ‘developed nations’. In the wake of these partnerships, a great variety of cross-national and cross-city agreements were signed. Sino-European cooperation does not often run as smoothly as initially hoped because of diverging interests, cultural misunderstandings and practical limitations. In the background, a mismatch in normative conceptions Chinese and European participants have of ‘good governance’ plays a role. In this contribution, insights taken from Montesquieu’s ‘The Spirit of Laws’ regarding checks and balances and trias politica (updated to ‘sextas politica’ for the 21st century) are used to comprehend how the exertion of power is distributed and expected to be distributed differently in Chinese than in European administrative traditions. The article will end with conclusions on how European misconceptions of Chinese governance complicate Sino-European collaboration in sustainable urbanization policies.","sustainable urbanization; Sino-European collaboration; Montesquieu; checks and balances; sextas politica; OA-Fund TU Delft","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:72a3d6d7-d7ff-40f1-ba1c-b8a2706c5e17","http://resolver.tudelft.nl/uuid:72a3d6d7-d7ff-40f1-ba1c-b8a2706c5e17","Measuring lean implementation for maintenance service companies","de Jong, Stephan J.; Beelaerts van Blokland, W.W.A. (TU Delft Transport Engineering and Logistics)","","2016","Purpose – Implementation of lean manufacturing is currently performed in the production industry; however, for the airline maintenance service industry, it is still in its infancy. Indicators such as work in process, cycle time, on-time performance and inventory are useful indicators to measure lean implementation; however, a financial economic perspective taking fixed assets into consideration is still missing. Hence, the purpose of this paper is to propose a method to measure lean implementation from a fixed asset perspective for this type of industry. With the indicators, continuous improvement scenarios can be explored by value stream discrete event simulation. Design/methodology/approach – From literature, indicators regarding asset specificity to measure lean implementation are found. These indicators are analysed by a linear least square method to know if variables are interrelated to form a preliminary model. The indicators are tested by value stream-based discrete event simulation regarding continuous improvement scenarios. Findings – With the new found lean transaction cost efficiency indicators, namely, turnover, gross margin and inventory pre-fixed asset (T/FA, GM/FA and I/FA, respectively), it is possible to measure operation performance from an asset specificity perspective under the influence of lean implementation. Secondly, the results of implementing continuous improvement scenarios are measured with the new indicators by a discrete event simulation. Research limitations/implications – This research is limited to the airline maintenance, repair and overhaul (MRO) service industry regarding component repair. Further research is necessary to test the indicators regarding other airline MRO service companies and other sectors of complex service industries like health care. Practical implications – The lean transaction cost efficiency model provides the capability for a maintenance service company to simulate the effects of process improvements on operation performance for service-based companies prior to implementation. Social/implications – Simulation of a Greenfield process can involve employees with possible changes in processes. This approach supports the adoption of anticipated changes. Originality/value – The found indicators form a preliminary model, which contributes to the usage and linkage of theories on lean manufacturing and transaction cost theory – asset specificity.","Asset specificity; Implementation; Lean; MRO aviation; Simulation; Transaction cost","en","journal article","","","","","","Accepted Author Manuscript","","2017-03-09","","","Transport Engineering and Logistics","","",""
"uuid:5c7c0315-edb9-4b53-8a9e-f065d6379e49","http://resolver.tudelft.nl/uuid:5c7c0315-edb9-4b53-8a9e-f065d6379e49","PVA matches human liver in needle-tissue interaction","de Jong, T.L. (TU Delft Medical Instruments & Bio-Inspired Technology); Pluymen (student), L.H.; van Gerwen, D.J. (TU Delft Medical Instruments & Bio-Inspired Technology); Kleinrensink, GJ (Erasmus Universiteit Rotterdam); Dankelman, J. (TU Delft Medical Instruments & Bio-Inspired Technology); van den Dobbelsteen, J.J. (TU Delft Medical Instruments & Bio-Inspired Technology)","","2017","Medical phantoms can be used to study needle-tissue interaction and to train medical residents. The purpose of this research is to study the suitability of polyvinyl alcohol (PVA) as a liver tissue mimicking material in terms of needle-tissue interaction. Insertions into ex-vivo human livers were used for reference. Six PVA samples were created by varying the mass percentage of PVA to water (4 m% and 7 m%) and the number of freeze-thaw cycles (1, 2 and 3 cycles, 16 hours of freezing at −19 °C, 8 hours of thawing). The inner needle of an 18 Gauge trocar needle with triangular tip was inserted 13 times into each of the samples, using an insertion velocity of 5 mm/s. In addition, 39 insertions were performed in two ex-vivo human livers. Axial forces on the needle were captured during insertion and retraction and characterized by friction along the needle shaft, peak forces, and number of peak forces per unit length. The concentration of PVA and the number of freeze-thaw cycles both influenced the mechanical interaction between needle and specimen. Insertions into 4 m% PVA phantoms with 2 freeze-thaw cycles were comparable to human liver in terms of estimated friction along the needle shaft and the number of peak forces. Therefore, these phantoms are considered to be suitable liver mimicking materials for image-guided needle interventions. The mechanical properties of PVA hydrogels can be influenced in a controlled manner by varying the concentration of PVA and the number of freeze-thaw cycles, to mimic liver tissue characteristics.","Medical phantoms; Needle-tissue interaction; Polyvinyl alcohol (PVA) hydrogel; Radiologic liver interventions; Tissue mimicking material","en","journal article","","","","","","Accepted Author Manuscript","","2019-01-10","","","Medical Instruments & Bio-Inspired Technology","","",""
"uuid:3fbb5e68-4a1d-4bf2-9279-7fee1d6d67fa","http://resolver.tudelft.nl/uuid:3fbb5e68-4a1d-4bf2-9279-7fee1d6d67fa","Path Dependence in Financing Urban Infrastructure Development in China: 1949–2016","Zhan, C. (TU Delft Organisation & Governance); de Jong, W.M. (TU Delft Organisation & Governance); de Bruijn, J.A. (TU Delft Multi Actor Systems)","","2017","In the past few decades, urban infrastructures in China have seen an enormous upgrade, and due to large-scale urbanization many more investments are due in the coming years. In order to supplement public funding, Public Private Partnerships (PPP) and municipal bonds have recently grown popular in China. The introduction of this new policy does not occur in a void but should be understood as the path-dependent consequence of a historical evolution of funding arrangements for urban development. How have Chinese governments traditionally arranged financing for these extensive investments and how has the emphasis in funding sources shifted over time? We argue that the evolution of urban development financing has gone through three phases (planned economy, reform and pilot, and socialist market economy), each with different emphasis in financial sources. Our analysis demonstrates how weaknesses in earlier phases present challenges that new solutions in later phases are aimed to address.","Path dependence; Institution; Urban development; Finance; China","en","journal article","","","","","","","","","","Multi Actor Systems","Organisation & Governance","","",""
"uuid:ed2399b2-1039-404f-a2ed-39e00a888b56","http://resolver.tudelft.nl/uuid:ed2399b2-1039-404f-a2ed-39e00a888b56","Spatial spillover effects of environmental pollution in China's Central Plains Urban Agglomeration","Xiong, Lichun (Beijing Forestry University); de Jong, W.M. (TU Delft Organisation & Governance; Fudan University); Wang, Fengting (China Agricultural University); Cheng, Baodong (Beijing Forestry University); Yu, Chang (Beijing Forestry University)","","2018","Promoting the rise of Central China is one of the most important national strategies regarding the promotion of China's economic development. However, the environmental issues in the central regions have become remarkably severe. It is therefore worthwhile exploring how economic development and environmental protection can be coordinated. Focusing on the 29 prefecture-level cities in the Central Plains Urban Agglomeration, the authors empirically analyze the relationship between the economy and the environment from 2004 to 2014. The combined methods of the spatial autocorrelation model, the environmental Kuznets curve, and the global spatial correlation test are systematically employed. The results show that: (1) a strong spatial correlation exists between industrial wastewater discharge, industrial sulfur dioxide, and dust emissions in the Central Plains Urban Agglomeration; (2) the relationship between the economy and the environment of this urban agglomeration reveals an inverted ""U"" curve, which confirms the classical environmental Kuznets curve hypothesis. Industrial dust emissions have surpassed the inflection point of the Kuznets curve, but its spatial spillover effect still remains strong. This is caused by an accumulation effect and a lag effect; (3) the proportion of the secondary industry and population has a strong positive effect on pollution discharge; investments in science and technology have a certain inhibitory effect on industrial sulfur dioxide emission. Moreover, an increase in the number of industrial enterprises has a negative effect on industrial wastewater emission. At the end, the authors put forward policy recommendations regarding the establishment of a joint supervisory department and unified environmental standards at the regional level to deal with the spillover effects of pollution.","Central PlainsUrbanAgglomeration; EnvironmentKuznets Curve; Spatial auto-correlationmodel","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:53c2daa4-6097-4aaa-87cf-c7234c19fa5e","http://resolver.tudelft.nl/uuid:53c2daa4-6097-4aaa-87cf-c7234c19fa5e","‘If It Ain’t Broke, Don’t Explain It’: The Influence of Visual and Verbal Information about Prior Use on Consumers’ Evaluations of Refurbished Electronics","Mugge, R. (TU Delft Product Innovatie Management); de Jong, Wytske (Student TU Delft); Hultink, H.J. (TU Delft Marketing and Consumer Research); Person, Oscar (Aalto University)","","2018","Refurbishment presents opportunities for designers to improve the sustainability of new and old products via an experiment and post hoc interviews, this research investigates and explores how information about prior use – offered in a visual (signs of wear and tear) or verbal (textual description) form – influences consumers’ evaluations of refurbished products. The findings show that visual information about prior use has a negative effect on consumers’ evaluations of refurbished electronics. Furthermore, presenting consumers with verbal information on prior use can negatively affect consumers’ evaluations of a refurbished product if no signs of wear and tear are present because it confuses consumers. If signs of wear and tear are present, verbal information about prior use will not influence consumers’ evaluations.","circular economy; consumer behaviour; refurbished products; remanufacturing; wear and tear","en","journal article","","","","","","","","","","Product Innovatie Management","Marketing and Consumer Research","","",""
"uuid:7486481e-1e2e-4233-97c7-e122cc5d1cf6","http://resolver.tudelft.nl/uuid:7486481e-1e2e-4233-97c7-e122cc5d1cf6","Ensemble landmarking of 3D facial surface scans","de Jong, M.A. (Erasmus MC; Leiden University Medical Center); Hysi, Pirro (King’s College London); Spector, Tim (King’s College London); Niessen, W.J. (TU Delft ImPhys/Quantitative Imaging; Erasmus MC); Koudstaal, M.J. (Erasmus MC); Wolvius, Eppo B. (Erasmus MC); Kayser, Manfred (Erasmus MC); Böhringer, Stefan (Leiden University Medical Center)","","2018","Landmarking of 3D facial surface scans is an important analysis step in medical and biological applications, such as genome-wide association studies (GWAS). Manual landmarking is often employed with considerable cost and rater dependent variability. Landmarking automatically with minimal training is therefore desirable. We apply statistical ensemble methods to improve automated landmarking of 3D facial surface scans. Base landmarking algorithms using features derived from 3D surface scans are combined using either bagging or stacking. A focus is on low training complexity of maximal 40 training samples with template based landmarking algorithms that have proved successful in such applications. Additionally, we use correlations between landmark coordinates by introducing a search strategy guided by principal components (PCs) of training landmarks. We found that bagging has no useful impact, while stacking strongly improves accuracy to an average error of 1.7 mm across all 21 landmarks in this study, a 22% improvement as compared to a previous, comparable algorithm. Heritability estimates in twin pairs also show improvements when using facial distances from landmarks. Ensemble methods allow improvement of automatic, accurate landmarking of 3D facial images with minimal training which is advantageous in large cohort studies for GWAS and when landmarking needs change or data quality varies.","","en","journal article","","","","","","","","","","","ImPhys/Quantitative Imaging","","",""
"uuid:5301d889-a340-4250-ad28-7b36e71707e0","http://resolver.tudelft.nl/uuid:5301d889-a340-4250-ad28-7b36e71707e0","Towards Credible City Branding Practices: How Do Iran’s Largest Cities Face Ecological Modernization?","Noori, F. (TU Delft Organisation & Governance; Erasmus Universiteit Rotterdam); de Jong, W.M. (TU Delft Organisation & Governance; Erasmus Universiteit Rotterdam; Fudan University)","","2018","City branding is not only increasingly practiced in cities in established economies, but also among municipal governments in countries, until quite recently, rather closed off from the outside world. One country with a strong drive to engage in urban (re)development in the post-oil era through enhancing its ‘ecological modernization’ is Iran. Megacities in Iran have all begun to venture into making profiles of what they think they are or would like to be. However, some of the adopted city branding strategies lack sophistication. In this article, the authors examine what indicators can be used for evaluating the credibility of city brands and apply these to Iran’s 15 megacities. After offering brief descriptions of the generic features of each of these cities, they map their use of city brand identities and popular city labels related to ecological modernization and analyze the credibility of their city branding practices. Based on their findings, the authors distinguish five types of cities and explain what makes some types more credible in their use of brands than others. Generally speaking, compared to cities in other nations, Iranian cities pay special attention to historical, natural, cultural, and religious aspects.","city branding; ecological modernization; brand credibility; Iran; megacities; OA-Fund TU Delft","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:1717ead8-34f4-4bc0-945c-1c4f0fbba773","http://resolver.tudelft.nl/uuid:1717ead8-34f4-4bc0-945c-1c4f0fbba773","Transport Demand Management Policy Integration in Chinese Cities: A Proposed Analysis of Its Effects","Yang, W. (TU Delft Organisation & Governance); Veeneman, Wijnand (TU Delft Organisation & Governance); de Jong, W.M. (TU Delft Organisation & Governance)","","2018","Transport demand management (TDM) measures are widely regarded as essential tools to deal with traffic issues. Their effectiveness has been under scrutiny. Packaging of TDM measures has recently received much attention from researchers and governments because it can achieve more complex policy goals and resolve the negative effects of single TDM measures. Many studies have examined the concept of policy packaging, the ideal packaging process, and potential barriers at the theoretical level. However, the way TDM packaging as a concept works in a real-world context has received little attention. Additionally, there is little methodology to analyse its characteristics from a dynamic and historical perspective. Therefore, this study provides a methodology for analysing TDM packaging in four dimensions (i.e., density, classification, interaction, and time). These dimensions respectively reveal how many and what kind of TDM measures have been implemented, how they interact in a package, and how these characteristics change over time. We examine this methodology through comparative case studies based on policy document analysis in two Chinese cities, Dalian and Shenzhen, both of which adopt a large number of TDM measures. The results show that this methodology successfully reveals the characteristics of case cities: both tend to put more TDM measures into the transport policy package to deal with traffic issues, but the package in Shenzhen is more integrative than that in Dalian. We also find that with the integration of packaging increasing, transport systems are becoming more sustainable, and Shenzhen performs better in this regard than Dalian. This methodology can be used to analyse policy packaging in broader areas and to examine its influence on transport systems in more case studies in future research.","transport demand management (TDM); policy packaging; transport policy; congestion; emissions; Dalian; Shenzhen; China","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:e60bbbd6-bd9f-4e2c-bdd1-61b5ab6141c6","http://resolver.tudelft.nl/uuid:e60bbbd6-bd9f-4e2c-bdd1-61b5ab6141c6","The impact of dry torrefaction on the fast pyrolysis behavior of ash wood and commercial Dutch mixed wood in a pyroprobe","Tsalidis, G.A. (TU Delft Energie and Industrie); Tsekos, C. (TU Delft Large Scale Energy Storage); Anastasakis, K. (TU Delft Energy Technology; Aarhus University); de Jong, W. (TU Delft Large Scale Energy Storage; Rijksuniversiteit Groningen)","","2018","In this study torrefied feedstocks, consisting of mixed wood and wood residues torrefied at 300 °C and ash wood torrefied at 250 and 265 °C, were pyrolyzed in a pyroprobe at five pyrolysis temperatures (600–1000 °C) and a fast heating rate (600 °C·s−1) to investigate the effect of torrefaction on the formation of volatiles and their evolution in a 100 kW circulating fluidized bed gasifier. Results showed that torrefaction converted mostly the hemicellulose content of feedstocks. Furthermore, torrefaction resulted in decreasing the bio-oil and gas yields, increasing the char and phenol yields and not affecting the polyaromatic hydrocarbons yield. Phenol and naphthalene showed the largest yield at 600–700 °C and 800–1000 °C, respectively. At such high temperatures, the rest polyaromatic hydrocarbons showed yields similar to phenol's. At 900 °C torrefaction affected mainly the phenolic species, with 4-propyl-phenol being the dominant species of its group for mixed wood and wood residues feedstock. In the gasifier, H2 and CO2 yields increased, CH4 yield remained constant, and CO yield depended on tar conversion and oxidation and steam reactions. The phenol and naphthalene yields further decreased and increased, respectively, whereas, polyaromatic hydrocarbons did not change in the gasifier.","pyroprobe; torrefaction","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2018-11-08","","","Energie and Industrie","","",""
"uuid:e868926a-6102-470a-adf2-ba57c3cd4af7","http://resolver.tudelft.nl/uuid:e868926a-6102-470a-adf2-ba57c3cd4af7","Fluorescent metal organic frameworks for the visual enhancement of latent fingermarks","de Jong, R. (Netherlands Forensic Institute - NFI); de Puit, M. (TU Delft OLD ChemE/Organic Materials and Interfaces; Netherlands Forensic Institute - NFI)","","2018","Lanthanide-based (Eu and Tb) metal organic frameworks (MOFs) synthesized in this work are highly fluorescent crystalline structures that form through a self-assembly process in an aqueous environment. Various bio-organic molecules, including proteins and amino acids, can act as inducing agents for this process. The fact that these components are present in fingermark secretions, in combination with the excellent luminescent properties of the MOFs, create a visualisation method for (latent) fingermarks. The aqueous MOF precursor solutions are not ideal for the visualisation of latent fingermarks on non-porous surfaces, such as aluminium foil and glass. However, they offer a simple, non-toxic, long-lasting and effective approach for the visibility enhancement of fingermarks treated with cyanoacrylate fuming on aluminium foil and glass and latent fingermarks on the adhesive side of a transparent tape. The luminescent properties of MOF-treated fingermarks persevered for at least 12 months, providing great alternative for commonly used organic dyes such as Basic Yellow 40 and Gentian Violet. In this communication we evaluate the applicability of the proposed method for the forensic fingermark workflow.","Forensic analysis; Forensic chemistry; Latent traces; Metal organic frameworks","en","journal article","","","","","","","","2019-08-16","","","OLD ChemE/Organic Materials and Interfaces","","",""
"uuid:6c9b31d9-ae36-4b2f-ad96-a50b686f6e56","http://resolver.tudelft.nl/uuid:6c9b31d9-ae36-4b2f-ad96-a50b686f6e56","High Frame Rate Contrast-Enhanced Ultrasound for Velocimetry in the Human Abdominal Aorta","Voorneveld, J.D. (Erasmus MC); Engelhard, S. (Rijnstate Hospital); Vos, H.J. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Reijnen, M. (Rijnstate Hospital); Gijsen, F.J.H. (Erasmus MC); Versluis, M. (University of Twente); Jebbink, E. Groot (University of Twente); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Bosch, J. G. (Erasmus MC)","","2018","Treatment of abdominal aortic (AA) aneurysms and stenotic lesions may be improved by analyzing their associated blood flow patterns. Angle-independent blood flow patterns in the AA can be obtained by combining echo-particle image velocimetry (ePIV) with high frame rate contrast-enhanced ultrasonography. However, ePIV performance is affected by ultrasound contrast agent (UCA) concentration, microbubble stability and tissue clutter. In this study we assessed the influence of acoustic pressure and UCA concentration on image quality for ePIV analysis. We also compared amplitude modulation (AM) and singular value decomposition (SVD) as tissue suppression strategies for ePIV. Fourteen healthy volunteers were imaged in the region of the distal AA. We tested four different UCA bolus volumes (0.25, 0.5, 0.75 and 1.5 ml) and four different acoustic output pressures (mechanical indices: 0.01, 0.03, 0.06 and 0.09). As image quality metrics, we measured contrast-to-background ratio, bubble disruption ratio and maximum normalized cross-correlation value during ePIV. At mechanical indices ≥ 0.06, we detected severe bubble destruction, suggesting that very low acoustic pressures should be used for ePIV. SVD was able to suppress tissue clutter better than AM. The maximum tracking correlation was affected by both UCA concentration and flow rate, where at high flow rates, lower UCA concentrations resulted in slightly higher correlation values but more signal drop-outs during late diastole. High frame rate ePIV was successfully performed in the AA of healthy volunteers and shows promise for future studies in patients.","abdominal aorta; echo-particle image velocimetry; echography; ePIV; high frame rate ultrasound; ultrasound contrast agents; vascular flow","en","journal article","","","","","","Accepted Author manuscript","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:ada2732d-0a64-4806-aff1-0d3962aa4473","http://resolver.tudelft.nl/uuid:ada2732d-0a64-4806-aff1-0d3962aa4473","Nieuw adsorptiemateriaal lijkt zeer geschikt voor rwzi's","Schijfsma, Hidde (Student TU Delft); de Jong, Coen (Witteveen+Bos); van der Hoek, J.P. (TU Delft Sanitary Engineering; Waternet); Cassou, Frank (CycloPure)","","2018","Recentelijk is in het lab van professor Will Dichtel van Cornell University (Ithaca, New York) een nieuw adsorptiemateriaal ontwikkeld voor de verwijdering van microverontreinigingen. Deze unieke poreuze cyclodextrine polymeren (P-CDPs) kunnen een breed scala aan organische microverontreinigingen (in relevante concentraties) verwijderen en hebben daarnaast gunstige levenscycluskosten. En zijn dus zeer geschikt voor de toepassing in afvalwaterzuivering. P-CDP adsorptiemateriaal wordt op dit moment gecommercialiseerd door materiaal- en technologiebedrijf CycloPure onder de naam van High-Affinity Cyclodextrin Polymers
(HACP's).","","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2019-02-01","","","Sanitary Engineering","","",""
"uuid:e42a5e3e-d554-43fb-9047-d322f9f12156","http://resolver.tudelft.nl/uuid:e42a5e3e-d554-43fb-9047-d322f9f12156","Characterization of Contrast Agent Microbubbles for Ultrasound Imaging and Therapy Research","Mulvana, Helen (University of Glasgow); Browning, Richard J. (University of Oxford); Luan, Ying (King’s College London); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Tang, Meng-Xing (University of Oxford; Imperial College London); Eckersley, Robert J. (King’s College London); Stride, Eleanor (University of Oxford)","","2017","","Acoustic microscopy and imaging; medical imaging; therapeutics; ultrasound contrast agents (UCAs)","en","journal article","","","","","","","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:1246e9fe-4cc1-47c4-9845-91fe78ae7f90","http://resolver.tudelft.nl/uuid:1246e9fe-4cc1-47c4-9845-91fe78ae7f90","Non-spherical oscillations drive the ultrasound-mediated release from targeted microbubbles","Lajoinie, Guillaume (University of Twente); Luan, Ying (Erasmus MC); Gelderblom, Erik (University of Twente); Dollet, Benjamin (Grenoble Alps University/CNRS/IRD); Mastik, Frits (Erasmus MC); Dewitte, Heleen (Universiteit Gent); Lentacker, Ine (Universiteit Gent); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Versluis, Michel (University of Twente)","","2018","","","en","journal article","","","","","","","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:18c6968c-2def-48cb-a14d-a2871ea973ad","http://resolver.tudelft.nl/uuid:18c6968c-2def-48cb-a14d-a2871ea973ad","Immobilization of Prunus amygdalus Hydroxynitrile Lyase on Celite","Bracco Garcia, M.P. (TU Delft BT/Biocatalysis); Torrelo Villa, G. (TU Delft BT/Biocatalysis); Noordam, Sander (Student TU Delft); de Jong, Glenn; Hanefeld, U. (TU Delft BT/Biocatalysis)","","2018","The hydroxynitrile lyase from Prunus amygdalus was immobilized on Celite R-633. The immobilized enzyme could successfully be utilized in buffer saturated MTBE and excellent conversions of benzaldehyde to R-mandelonitrile were observed. No leaching occurred. To achieve high enantioselectivities, the suppression of the undesired background reaction was essential. This could be achieved by high enzyme loadings and the tight packing of the immobilized enzymes. When the immobilized enzyme is loosely packed, both the enzyme catalysis and the background reaction accelerates and only a modest enantioselectivity is observed. The enzyme was recycled for up to ten times, with some loss of activity and also enantioselectivity after 5 cycles, independent of packing.","biocatalysis; hydroxynitrile lyase; Oxynitrilase; immobilization; Celite; diffusion; cyanohydrin; OA-Fund TU Delft","en","journal article","","","","","","","","","","","BT/Biocatalysis","","",""
"uuid:37e6dd64-0ac6-409b-8611-46276e001981","http://resolver.tudelft.nl/uuid:37e6dd64-0ac6-409b-8611-46276e001981","Anterior longitudinal ligament in diffuse idiopathic skeletal hyperostosis: Ossified or displaced?","Kuperus, J.S. (University Medical Center Utrecht); Smit, E.J.M. (University Medical Center Utrecht); Pouran, B. (TU Delft Biomaterials & Tissue Biomechanics); van Hamersvelt, R.W. (University Medical Center Utrecht); van Stralen, Marijn (Universiteit Utrecht); Seevinck, P.R. (Universiteit Utrecht); Buckens, C.F. (University Medical Center Utrecht); Bleys, Ronald L.A.W. (University Medical Center Utrecht); Weinans, Harrie (TU Delft Biomaterials & Tissue Biomechanics); Oner, F. C. (University Medical Center Utrecht); de Jong, P.A. (University Medical Center Utrecht); Verlaan, J-J (University Medical Center Utrecht)","","2018","Diffuse idiopathic skeletal hyperostosis (DISH) is often theorized to be an ossification of the anterior longitudinal ligament (ALL). Using computed tomography (CT) imaging and cryomacrotome sectioning, we investigated the spatial relationship between the ALL and newly formed bone in DISH to test this hypothesis. In the current study, four human cadaveric spines diagnosed with DISH using CT imaging were frozen and sectioned using a cryomacrotome. Photographs were obtained of the specimen at 125 µm intervals. Manual segmentations of the ALL on cryomacrotome photographs were projected onto the three-dimensional reconstructed CT scans. The presence and location of newly formed bone were assessed in relationship to the location of the ALL. The ALL could be identified and segmented on the photographs at all levels. The ALL was located at the midline at levels where no new bone had formed. At the locations where new bone had abundantly formed, the ALL was displaced towards to the contralateral side and not replaced by bony tissue. The displacement of the—morphologically normal appearing—ALL away from the newly formed bone implies that newly formed bone in DISH may not originate from the ALL.","anterior longitudinal ligament; bone/bone biology; computed tomography; cryomacrotome; diffuse idiopathic skeletal hyperostosis; pathogenesis; spine","en","journal article","","","","","","","","","","","Biomaterials & Tissue Biomechanics","","",""
"uuid:18842c70-5946-4fc9-9322-198d890b8ca4","http://resolver.tudelft.nl/uuid:18842c70-5946-4fc9-9322-198d890b8ca4","Needle placement errors: do we need steerable needles in interventional radiology?","de Jong, T.L. (TU Delft Medical Instruments & Bio-Inspired Technology); van de Berg, N.J. (TU Delft Medical Instruments & Bio-Inspired Technology); Tas, L. (TU Delft Medical Instruments & Bio-Inspired Technology); Moelker, Adriaan (Erasmus MC); Dankelman, J. (TU Delft Medical Instruments & Bio-Inspired Technology); van den Dobbelsteen, J.J. (TU Delft Medical Instruments & Bio-Inspired Technology)","","2018","Purpose: Accurate and precise needle placement is of utmost importance in interventional radiology. However, targeting can be challenging due to, eg, tissue motion and deformation. Steerable needles are a possible solution to overcome these challenges. The present work studied the clinical need for steerable needles. We aimed to answer three subquestions: 1) What are the current challenges in needle placement? 2) What are allowable needle placement errors? and 3) Do current needles need improvement and would steerable needles add clinical value?
Methods: A questionnaire was administered at the Annual Meeting of Cardiovascular and Interventional Radiology Society of Europe in 2016. In total, 153 respondents volunteered to fill out the survey, among them 125 (interventional) radiologists with experience in needle placement.
Results: 1) Current challenges in needle placement include patient-specific and technical factors. Movement of the target due to breathing makes it most difficult to place a needle (90%). 2) The mean maximal allowable needle placement error in targeted lesions is 2.7 mm. A majority of the respondents (85%) encounter unwanted needle bending upon insertion. The mean maximal encountered unwanted needle bending is 5.3 mm. 3) Needles in interventional radiology need improvement, eg, improved needle visibility and manipulability, according to 95% of the respondents. Added value for steerable needles in current interventions is seen by 93% of the respondents.
Conclusion: Steerable needles have the potential to add clinical value to radiologic interventions. The current data can be used as input for defining clinical design requirements for technical tools, such as steerable needles and navigation models, with the aim to improve needle placement in interventional radiology.","clinical use; interventional radiology; needle bending; needle deflection; needle placement error; questionnaire; steerable needle","en","journal article","","","","","","","","","","","Medical Instruments & Bio-Inspired Technology","","",""
"uuid:a2eedfc9-8a3d-49a3-a382-a6a069bf91ed","http://resolver.tudelft.nl/uuid:a2eedfc9-8a3d-49a3-a382-a6a069bf91ed","Consensus molecular subtype classification of colorectal adenomas","Komor, Malgorzata A. (Netherlands Cancer Institute; Amsterdam UMC); Bosch, Linda J.W. (Netherlands Cancer Institute); Bounova, Gergana (Netherlands Cancer Institute); Bolijn, Anne S. (Netherlands Cancer Institute); Delis‐van Diemen, Pien M. (Netherlands Cancer Institute); Rausch, Christian (Netherlands Cancer Institute); Hoogstrate, Youri (Erasmus MC); Stubbs, Andrew P. (Erasmus MC); de Jong, Mark (GenomeScan); Wessels, L.F.A. (TU Delft Pattern Recognition and Bioinformatics)","","2018","Consensus molecular subtyping is an RNA expression-based classification system for colorectal cancer (CRC). Genomic alterations accumulate during CRC pathogenesis, including the premalignant adenoma stage, leading to changes in RNA expression. Only a minority of adenomas progress to malignancies, a transition that is associated with specific DNA copy number aberrations or microsatellite instability (MSI). We aimed to investigate whether colorectal adenomas can already be stratified into consensus molecular subtype (CMS) classes, and whether specific CMS classes are related to the presence of specific DNA copy number aberrations associated with progression to malignancy. RNA sequencing was performed on 62 adenomas and 59 CRCs. MSI status was determined with polymerase chain reaction-based methodology. DNA copy number was assessed by low-coverage DNA sequencing (n = 30) or array-comparative genomic hybridisation (n = 32). Adenomas were classified into CMS classes together with CRCs from the study cohort and from The Cancer Genome Atlas (n = 556), by use of the established CMS classifier. As a result, 54 of 62 (87%) adenomas were classified according to the CMS. The CMS3 ‘metabolic subtype’, which was least common among CRCs, was most prevalent among adenomas (n = 45; 73%). One of the two adenomas showing MSI was classified as CMS1 (2%), the ‘MSI immune’ subtype. Eight adenomas (13%) were classified as the ‘canonical’ CMS2. No adenomas were classified as the ‘mesenchymal’ CMS4, consistent with the fact that adenomas lack invasion-associated stroma. The distribution of the CMS classes among adenomas was confirmed in an independent series. CMS3 was enriched with adenomas at low risk of progressing to CRC, whereas relatively more high-risk adenomas were observed in CMS2. We conclude that adenomas can be stratified into the CMS classes. Considering that CMS1 and CMS2 expression signatures may mark adenomas at increased risk of progression, the distribution of the CMS classes among adenomas is consistent with the proportion of adenomas expected to progress to CRC.","adenoma; colon; colorectal cancer; neoplasia; rectum","en","journal article","","","","","","","","","","","Pattern Recognition and Bioinformatics","","",""
"uuid:d588be69-fe96-4848-b6e1-7538e8711797","http://resolver.tudelft.nl/uuid:d588be69-fe96-4848-b6e1-7538e8711797","Conceptual models for short-eccentricity-scale climate control on peat formation in a lower Palaeocene fluvial system, north-eastern Montana (USA)","Noorbergen, Lars J. (Vrije Universiteit Amsterdam); Abels, H.A. (TU Delft Applied Geology); Hilgen, Frederik J. (Universiteit Utrecht); Robson, Brittany E. (Royal Holloway University of London); de Jong, Edwin (Universiteit Utrecht); Dekkers, Mark J. (Universiteit Utrecht); Krijgsman, Wout (Universiteit Utrecht); Smit, Jan (Vrije Universiteit Amsterdam); Collinson, Margaret E. (Royal Holloway University of London); Kuiper, Klaudia F. (Vrije Universiteit Amsterdam)","","2017","Fluvial systems in which peat formation occurs are typified by autogenic processes such as river meandering, crevasse splaying and channel avulsion. Nevertheless, autogenic processes cannot satisfactorily explain the repetitive nature and lateral continuity of many coal seams (compacted peats). The fluvial lower Palaeocene Tullock Member of the Fort Union Formation (Western Interior Williston Basin; Montana, USA) contains lignite rank coal seams that are traceable over distances of several kilometres. This sequence is used to test the hypothesis that peat formation in the fluvial system was controlled by orbitally forced climate change interacting with autogenic processes. Major successions are documented with an average thickness of 6·8 m consisting of ca 6 m thick intervals of channel and overbank deposits overlain by ca 1 m thick coal seam units. These major coal seams locally split and merge. Time-stratigraphic correlation, using a Cretaceous-Palaeogene boundary event horizon, several distinctive volcanic ash-fall layers, and the C29r/C29n magnetic polarity reversal, shows consistent lateral recurrence of seven successive major successions along a 10 km wide fence panel perpendicular to east/south-east palaeo-flow. The stratigraphic pattern, complemented by stratigraphic age control and cyclostratigraphic tests, suggests that the major peat-forming phases, resulting in major coal seams, were driven by 100 kyr eccentricity-related climate cycles. Two distinct conceptual models were developed, both based on the hypothesis that the major peat-forming phases ended when enhanced seasonal contrast, at times of minimum precession during increasing eccentricity, intensified mire degradation and flooding. In model 1, orbitally forced climate change controls the timing of peat compaction, leading to enhancement of autogenic channel avulsions. In model 2, orbitally forced climate change controls upstream sediment supply and clastic influx determining the persistence of peat-forming conditions. At the scale of the major successions, model 2 is supported because interfingering channel sandstones do not interrupt lateral continuity of major coal seams.","Conceptual model; Fluvial system; Lignite rank coal; North-eastern Montana; Orbitally forced climate change; Palaeocene; Peat formation; Time-stratigraphic correlation","en","journal article","","","","","","","","","","","Applied Geology","","",""
"uuid:d977d490-9429-444a-97bb-a9597de0dc73","http://resolver.tudelft.nl/uuid:d977d490-9429-444a-97bb-a9597de0dc73","Utilizing high-energy γ-photons for high-resolution 213Bi SPECT in mice","De Swart, Jan (Erasmus MC); Chan, Ho Sze (Erasmus MC); Goorden, M.C. (TU Delft RST/Biomedical Imaging); Morgenstern, Alfred (European Commission Joint Research Centre, Institute for Transuranium Elements Karlsruhe); Bruchertseifer, Frank (European Commission Joint Research Centre, Institute for Transuranium Elements Karlsruhe); Beekman, F.J. (TU Delft RST/Biomedical Imaging; MILabs B.V.; Brain Center Rudolf Magnus); de Jong, M. (Erasmus MC); Konijnenberg, Mark W. (Erasmus MC)","","2016","The combined α-, γ-, and x-ray emitter 213Bi (half-life, 46 min) is promising for radionuclide therapy. SPECT imaging of 213Bi is challenging, because most emitted photons have a much higher energy (440 keV) than common in SPECT. We assessed 213Bi imaging capabilities of the Versatile Emission Computed Tomograph (VECTor) dedicated to (simultaneous) preclinical imaging of both SPECT and PET isotopes over a wide photon energy range of 25-600 keV. Methods: VECTor was equipped with a dedicated clustered pinhole collimator. Both the 79 keV x-rays and the 440 keV γ-rays emitted by 213Bi could be imaged. Phantom experiments were performed to determine the maximum resolution, contrast-to-noise ratio, and activity recovery coefficient for different energy window settings. Additionally, imaging of [213Bi-DOTA,Tyr3]octreotate and 213Bi-diethylene triamine pentaacetic acid (DTPA) in mouse models was performed. Results: Using 440 keV γ-rays instead of 79 keV x-rays in image reconstruction strongly improved the resolution (0.75 mm) and contrast-to-noise characteristics. Results obtained with a single 440 keV energy window setting were close to those with a combined 79 keV/440 keV window. We found a reliable activity recovery coefficient down to 0.240 MBq/mL with 30-min imaging time. In a tumor-bearing mouse injected with 3 MBq of [213Bi-DOTA,Tyr3]octreotate, tumor uptake could be visualized with a 1-h postmortem scan. Imaging a nontumor mouse at 5-min frames after injection of 7.4 MBq of 213Bi-DTPA showed renal uptake and urinary clearance, visualizing the renal excretion pathway from cortex to ureter. Quantification of the uptake data allowed kinetic modeling and estimation of the absorbed dose to the kidneys. Conclusion: It is feasible to image 213Bi down to a 0.75-mm resolution using a SPECT system equipped with a dedicated collimator.","Bi; SPECT; Ultra-high-energy","en","journal article","","","","","","","","","","","RST/Biomedical Imaging","","",""
"uuid:fcc6773c-6180-4b47-ae42-9c339e268782","http://resolver.tudelft.nl/uuid:fcc6773c-6180-4b47-ae42-9c339e268782","Urban experimentation and institutional arrangements","Raven, Rob (Universiteit Utrecht); Sengers, Frans (Universiteit Utrecht); Spaeth, Philipp (Albert-Ludwigs-Universität Freiburg); Xie, Linjun (The University of Nottingham Ningbo China); Cheshmehzangi, Ali (The University of Nottingham Ningbo China); de Jong, W.M. (TU Delft Organisation & Governance; Fudan University)","","2017","Currently little is known about how institutional arrangements co-evolve with urban experimentation. This paper mobilizes neo-institutional literature and recent urban experimentation literature as a framework to explore how and why institutional arrangements differ across urban contexts. Empirically the paper focusses on smart city initiatives in Amsterdam, Hamburg and Ningbo. These three cities are frontrunners in adopting a comprehensive smart city agenda, but they do so in different ways. The paper examines regulative, normative and cognitive elements of institutional arrangements, explores how they shape experimentation, and reflects on their place-based specificities. The comparative analysis suggests that the focus of, and approach to, experimentation can be understood as resting in a (possibly unique) combination of strategic agency and dynamics at multiple spatial scales.","comparative case study; institutional arrangements; smart cities; Urban experimentation","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:432beff3-10ef-46db-a99a-84b2adc496ac","http://resolver.tudelft.nl/uuid:432beff3-10ef-46db-a99a-84b2adc496ac","The effect of torrefaction on the process performance of oxygen-steam blown CFB gasification of hardwood and softwood","Tsalidis, G.A. (TU Delft Large Scale Energy Storage); Di Marcello, M. (TU Delft Energy Technology); Spinelli, G. (University of Teramo); de Jong, W. (TU Delft Large Scale Energy Storage; Rijksuniversiteit Groningen); Kiel, J.H.A. (TU Delft Energy Technology; ECN, Petten)","","2017","Torrefaction is a promising biomass upgrading method, offering advantages in logistics and handling. Gasification is an attractive thermochemical conversion technology due to its flexibility in the product gas end-use. The aim of this paper is to investigate the impact of torrefaction on the gasification performance of a softwood (spruce) and a hardwood (ash). Spruce and ash were torrefied at 260 and 280 °C, and at 250 and 265 °C, respectively, and pelletized. All feedstocks were gasified at 850 °C and atmospheric pressure under oxygen-steam circulating fluidized bed gasification conditions, with magnesite as bed material and with an equivalence ratio (ER) of 0.3 and a steam-to-biomass mass ratio (SBR) of 1.0. Only the torrefied feedstocks were gasified varying ER and SBR values. The results show that torrefaction affected the gasification performance of both feedstocks leading to decreasing the cold gas and carbon conversion efficiencies. For spruce, torrefaction did not affect the permanent gas composition but led to a decrease of the total tar content for both spruce 260 and spruce 280. For ash, torrefaction resulted in decreasing the CH4 volume fraction, and increasing the H2 volume fraction and the total tar content for both torrefaction temperatures. Varying the ER and SBR affected only the Class 3 tars of ash 250. Conclusively, torrefaction of spruce and ash did not offer substantial benefits on the gasification performance under the investigated conditions. It is suggested that research of torrefied wood gasification includes feedstock's chemical analysis and characterization of products obtained under fast devolatilization conditions.","Circulating fluidized bed gasification; Hardwood; Softwood; Tar; Torrefaction","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:71b81644-e487-4fc1-aa6b-b691e2d90de2","http://resolver.tudelft.nl/uuid:71b81644-e487-4fc1-aa6b-b691e2d90de2","Automated Ischemic Lesion Segmentation in MRI Mouse Brain Data after Transient Middle Cerebral Artery Occlusion","Mulder, Inge A. (Leiden University Medical Center); Khmelinskii, Artem (Leiden University Medical Center; Percuros B.V); Dzyubachyk, Oleh (Leiden University Medical Center); de Jong, Sebastiaan (Leiden University Medical Center); Rieff, Nathalie (Leiden University Medical Center); Wermer, Marieke J.H. (Leiden University Medical Center); Hoehn, Mathias (Leiden University Medical Center; Percuros B.V; Max Planck Institute for Metabolism Research); Lelieveldt, B.P.F. (TU Delft Pattern Recognition and Bioinformatics; Leiden University Medical Center); van den Maagdenberg, Arn M.J.M. (Leiden University Medical Center)","","2017","Magnetic resonance imaging (MRI) has become increasingly important in ischemic stroke experiments in mice, especially because it enables longitudinal studies. Still, quantitative analysis of MRI data remains challenging mainly because segmentation of mouse brain lesions in MRI data heavily relies on time-consuming manual tracing and thresholding techniques. Therefore, in the present study, a fully automated approach was developed to analyze longitudinal MRI data for quantification of ischemic lesion volume progression in the mouse brain. We present a level-set-based lesion segmentation algorithm that is built using a minimal set of assumptions and requires only one MRI sequence (T2) as input. To validate our algorithm we used a heterogeneous data set consisting of 121 mouse brain scans of various age groups and time points after infarct induction and obtained using different MRI hardware and acquisition parameters. We evaluated the volumetric accuracy and regional overlap of ischemic lesions segmented by our automated method against the ground truth obtained in a semi-automated fashion that includes a highly time-consuming manual correction step. Our method shows good agreement with human observations and is accurate on heterogeneous data, whilst requiring much shorter average execution time. The algorithm developed here was compiled into a toolbox and made publically available, as well as all the data sets.","Automated segmentation; Ischemic stroke; Lesion; Mouse; MRI; Quantification; Volume","en","journal article","","","","","","","","","","","Pattern Recognition and Bioinformatics","","",""
"uuid:15e16ac6-db15-4958-924a-ce47596db528","http://resolver.tudelft.nl/uuid:15e16ac6-db15-4958-924a-ce47596db528","A Framework for Incorporation of Infeed Uncertainty in Power System Risk-Based Security Assessment","de Jong, M.A. (TU Delft Numerical Analysis); Papaefthymiou, G. (TU Delft Intelligent Electrical Power Grids); Palensky, P. (TU Delft Intelligent Electrical Power Grids)","","2018","In this paper, a risk-based security assessment methodology is presented, which allows the assessment of operational security of a power system’s future state under uncertainty deriving from varying topology scenarios (contingencies) and forecast errors (loads and renewable infeeds). The methodology models input uncertaintywith a copula function-based Monte–Carlo (MC) framework. Furthermore, it provides the highest level of accuracy on initiating causes of failures through an AC power flow (AC PF) framework. Finally, it achieves speed in solution by the combination of twomeasures of risk. A fast screening tool, based on severity functions, allows us to quickly screen the system for the most severe states. A detailed analysis tool, based on an AC optimal power flow (AC OPF) framework and the notion of lost load, provides additional valuable information, including remedial actions to steer away from severe system states. This paper presents results from the application of the methodology proving the necessity of such a framework. It is shown that not taking into account stochastic
dependence through a proper MC setup seriously underestimates system risk and that an AC framework is needed, as voltage deviations are shown to often be initiators of system collapse.","AC OPF; Monte-Carlo simulation; RBSA; copula theory; correlation; severity functions; stochastic dependence","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2021-12-08","","","Numerical Analysis","","",""
"uuid:3d792a97-a204-483f-94b5-6bd82f278b2f","http://resolver.tudelft.nl/uuid:3d792a97-a204-483f-94b5-6bd82f278b2f","On the dynamics of StemBells: Microbubble-conjugated stem cells for ultrasound-controlled delivery","Kokhuis, Tom J A (Erasmus MC; Netherlands Heart Institute); Naaijkens, Benno A. (Netherlands Heart Institute; Amsterdam UMC); Juffermans, Lynda J.M. (Netherlands Heart Institute; Amsterdam UMC); Kamp, Otto (Netherlands Heart Institute; Amsterdam UMC); van der Steen, A.F.W. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC; Netherlands Heart Institute; Shenzhen Institutes of Advanced Technology); Versluis, Michel (University of Twente); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC; Netherlands Heart Institute)","","2017","The use of stem cells for regenerative tissue repair is promising but hampered by the low number of cells delivered to the site of injury. To increase the delivery, we propose a technique in which stem cells are linked to functionalized microbubbles, creating echogenic complex dubbed StemBells. StemBells are highly susceptible to acoustic radiation force which can be employed after injection to push the StemBells locally to the treatment site. To optimally benefit from the delivery technique, a thorough characterization of the dynamics of StemBells during ultrasound exposure is needed. Using high-speed optical imaging, we study the dynamics of StemBells as a function of the applied frequency from which resonance curves were constructed. A theoretical model, based on a modified Rayleigh-Plesset type equation, captured the experimental resonance characteristics and radial dynamics in detail.","","en","journal article","","","","","","","","2018-07-11","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:a46b8987-295d-4eb6-919b-b7dc631f024d","http://resolver.tudelft.nl/uuid:a46b8987-295d-4eb6-919b-b7dc631f024d","A split-cavity design for the incorporation of a DC bias in a 3D microwave cavity","Cohen, M.A. (TU Delft QN/Steele Lab); Yuan, M. (TU Delft QN/Steele Lab); de Jong, B.W.A. (Student TU Delft); Beukers, Ewout (Student TU Delft); Bosman, S.J. (TU Delft QN/Steele Lab); Steele, G.A. (TU Delft QN/Steele Lab)","","2017","We report on a technique for applying a DC bias in a 3D microwave cavity. We achieve this by isolating the two halves of the cavity with a dielectric and directly using them as DC electrodes. As a proof of concept, we embed a variable capacitance diode in the cavity and tune the resonant frequency with a DC voltage, demonstrating the incorporation of a DC bias into the 3D cavity with no measurable change in its quality factor at room temperature. We also characterize the architecture at millikelvin temperatures and show that the split cavity design maintains a quality factor Qi ∼ 8.8 × 105, making it promising for future quantum applications.","","en","journal article","","","","","","","","2018-04-24","","","QN/Steele Lab","","",""
"uuid:7bda72ca-2b6e-416b-8eed-297134fae56e","http://resolver.tudelft.nl/uuid:7bda72ca-2b6e-416b-8eed-297134fae56e","Microbubble Composition and Preparation for High-Frequency Contrast-Enhanced Ultrasound Imaging: In Vitro and in Vivo Evaluation","Daeichin, Verya (Erasmus Universiteit Rotterdam); van Rooij, Tom (Erasmus Universiteit Rotterdam); Skachkov, Ilya (Erasmus Universiteit Rotterdam; Universiteit Utrecht); Ergin, Bulent (Universiteit van Amsterdam); Specht, Patricia A.C. (Erasmus Universiteit Rotterdam); Lima, Alexandre (Erasmus Universiteit Rotterdam); Ince, Can (Erasmus Universiteit Rotterdam); Bosch, Johan G. (Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC; Shenzhen Institute of Advanced Technologies); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Netherlands Heart Institute; Erasmus Universiteit Rotterdam); Kooiman, Klazina (Erasmus MC)","","2017","Although high-frequency ultrasound imaging is gaining attention in various applications, hardly any ultrasound contrast agents (UCAs) dedicated to such frequencies (>15 MHz) are available for contrast-enhanced ultrasound (CEUS) imaging. Moreover, the composition of the limited commercially available UCAs for high-frequency CEUS (hfCEUS) is largely unknown, while shell properties have been shown to be an important factor for their performance. The aim of our study was to produce UCAs in-house for hfCEUS. Twelve different UCA formulations A-L were made by either sonication or mechanical agitation. The gas core consisted of C4F10 and the main coating lipid was either 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC; A-F formulation) or 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC; G-L formulation). Mechanical agitation resulted in UCAs with smaller microbubbles (number weighted mean diameter ∼1 μm) than sonication (number weighted mean diameter ∼2 μm} ). UCA formulations with similar size distributions but different main lipid components showed that the DPPC-based UCA formulations had higher nonlinear responses at both the fundamental and subharmonic frequencies in vitro for hfCEUS using the Vevo2100 high-frequency preclinical scanner (FUJIFILM VisualSonics, Inc.). In addition, UCA formulations F (DSPC-based) and L (DPPC-based) that were made by mechanical agitation performed similar in vitro to the commercially available Target-Ready MicroMarker (FUJIFILM VisualSonics, Inc.). UCA formulation F also performed similar to Target-Ready MicroMarker in vivo in pigs with similar mean contrast intensity within the kidney ( n = 7 ), but formulation L did not. This is likely due to the lower stability of formulation L in vivo. Our study shows that DSPC-based microbubbles produced by mechanical agitation resulted in small microbubbles with high nonlinear responses suitable for hfCEUS imaging.","Contrast agent; Contrast-enhanced ultrasound (CEUS) imaging; High-frequency; in vitro; in vivo; Microbubble","en","journal article","","","","","","","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:389c851c-5309-48fd-8065-c5ada341313e","http://resolver.tudelft.nl/uuid:389c851c-5309-48fd-8065-c5ada341313e","Cardiac Shear Wave Elastography Using a Clinical Ultrasound System","Strachinaru, Mihai (Erasmus MC); Bosch, Johan G. (Erasmus MC); van Dalen, Bas M. (Erasmus MC); van Gils, Lennart (Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Geleijnse, Marcel L. (Erasmus MC); Vos, H.J. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC)","","2017","The propagation velocity of shear waves relates to tissue stiffness. We prove that a regular clinical cardiac ultrasound system can determine shear wave velocity with a conventional unmodified tissue Doppler imaging (TDI) application. The investigation was performed on five tissue phantoms with different stiffness using a research platform capable of inducing and tracking shear waves and a clinical cardiac system (Philips iE33, achieving frame rates of 400–700 Hz in TDI by tuning the normal system settings). We also tested the technique in vivo on a normal individual and on typical pathologies modifying the consistency of the left ventricular wall. The research platform scanner was used as reference. Shear wave velocities measured with TDI on the clinical cardiac system were very close to those measured by the research platform scanner. The mean difference between the clinical and research systems was 0.18 ± 0.22 m/s, and the limits of agreement, from −0.27 to +0.63 m/s. In vivo, the velocity of the wave induced by aortic valve closure in the interventricular septum increased in patients with expected increased wall stiffness.","Elastography; High-frame-rate tissue Doppler; Shear waves; Stiffness","en","journal article","","","","","","","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:c9ee5be2-af5a-4eab-8b7c-a4eadeca8923","http://resolver.tudelft.nl/uuid:c9ee5be2-af5a-4eab-8b7c-a4eadeca8923","Countermeasures of Zero-missing Phenomenon in (E)HV Cable Systems","Khalilnezhad, H. (TU Delft Intelligent Electrical Power Grids); Popov, M. (TU Delft Intelligent Electrical Power Grids); van der Sluis, L. (TU Delft EEMS - General); Bos, Jorrit A. (TenneT TSO B.V.); de Jong, Jan P.W. (TenneT TSO B.V.); Ametani, Akihiro (Doshisha University)","","2018","Zero-missing is a phenomenon in shunt compensated cable systems in which the current through the line breaker does not cross the zero point for several cycles. This paper deals with a thorough investigation on countermeasures of the zero-missing phenomenon in transmission systems and determines the requirements, benefits, and risks of applying each method. The effectiveness of countermeasures is studied on a simulated cable project with different cable lengths in an actual grid model of the Dutch 380 kV transmission system. Results are analyzed based on three criteria related to the IEC standards and the Dutch grid code. In addition, the switching sequence of circuit-breakers is specified to maximize the effectiveness of the countermeasures. A statistical switching analysis is performed for the insulation coordination study since the application of some countermeasures increases the probability of high transient switching overvoltages. Moreover, the closing variation threshold of circuit-breakers is calculated as a function of the circuit impedance and the shunt compensation degree.","Cables; circuit breakers; Inductors; RLC circuits; shunt reactor; Shunts (electrical); statistical analysis; Surges; Switches; Switching circuits; switching transients; Transient analysis; zero-missing phenomenon","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2021-08-17","","","Intelligent Electrical Power Grids","","",""
"uuid:8ec93ff7-6c67-460f-a0fb-5009059fea82","http://resolver.tudelft.nl/uuid:8ec93ff7-6c67-460f-a0fb-5009059fea82","Vibrational Responses of Bound and Nonbound Targeted Lipid-Coated Single Microbubbles","van Rooij, Tom (Erasmus MC); Beekers, D.I. (Erasmus MC); Lattwein, Kirby R. (Erasmus MC); van der Steen, A.F.W. (Erasmus MC); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Kooiman, Klazina (Erasmus MC)","","2017","One of the main challenges for ultrasound molecular imaging is acoustically distinguishing nonbound microbubbles from those bound to their molecular target. In this in vitro study, we compared two types of in-house produced targeted lipid-coated microbubbles, either consisting of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine, C16:0 (DPPC) or 1,2-distearoyl-sn-glycero-3-phosphocholine, C18:0 (DSPC) as the main lipid, using the Brandaris 128 ultrahigh-speed camera to determine vibrational response differences between bound and nonbound biotinylated microbubbles. In contrast to previous studies that studied vibrational differences upon binding, we used a covalently bound model biomarker (i.e., streptavidin) rather than physisorption, to ensure binding of the biomarker to the membrane. The microbubbles were insonified at frequencies between 1 and 4 MHz at pressures of 50 and 150 kPa. This paper shows lower acoustic stability of bound microbubbles, of which DPPC-based microbubbles deflated most. For DPPC microbubbles with diameters between 2 and 4μm driven at 50 kPa, resonance frequencies of bound microbubbles were all higher than 1.8 MHz, whereas those of nonbound microbubbles were significantly lower. In addition, the relative radial excursions at resonance were also higher for bound DPPC microbubbles. These differences did not persist when the pressure was increased to 150 kPa, except for the acoustic stability which further decreased. No differences in resonance frequencies were observed between bound and nonbound DSPC microbubbles. Nonlinear responses in terms of emissions at the subharmonic and second harmonic frequencies were similar for bound and nonbound microbubbles at both pressures. In conclusion, we identified differences in vibrational responses of bound DPPC microbubbles with diameters between 2 and 4μm that distinguish them from nonbound ones.","Biotin-streptavidin; lipid-coating; molecular imaging; nonlinear behavior; targeted microbubbles; ultrahigh-speed optical imaging; ultrasound contrast agents","en","journal article","","","","","","","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:147c2809-708d-451e-a20d-beac610ed36f","http://resolver.tudelft.nl/uuid:147c2809-708d-451e-a20d-beac610ed36f","Compressive 3D ultrasound imaging using a single sensor","Kruizinga, P. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); van der Meulen, P.F. (TU Delft Applications); Fedjajevs, A. (Student TU Delft); Mastik, F (Erasmus MC); Springeling, Geert (Erasmus MC); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Bosch, J.G. (Erasmus MC); Leus, G.J.T. (TU Delft Signal Processing Systems)","","2017","Three-dimensional ultrasound is a powerful imaging technique, but it requires thousands of sensors and complex hardware. Very recently, the discovery of compressive sensing has shown that the signal structure can be exploited to reduce the burden posed by traditional sensing requirements. In this spirit, we have designed a simple ultrasound imaging device that can perform three-dimensional imaging using just a single ultrasound sensor. Our device makes a compressed measurement of the spatial ultrasound field using a plastic aperture mask placed in front of the ultrasound sensor. The aperture mask ensures that every pixel in the image is uniquely identifiable in the compressed measurement. We demonstrate that this device can successfully image two structured objects placed in water. The need for just one sensor instead of thousands paves the way for cheaper, faster, simpler, and smaller sensing devices and possible new clinical applications.","","en","journal article","","","","","","","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:cfbbd683-05e7-43f9-bae4-c445023f38bc","http://resolver.tudelft.nl/uuid:cfbbd683-05e7-43f9-bae4-c445023f38bc","A Tale of Two Chinese Transit Metropolises and the Implementation of Their Policies: Shenyang and Dalian (Liaoning Province, China)","Mu, R. (Dalian University of Technology); de Jong, W.M. (TU Delft Organisation & Governance; Fudan University)","","2018","To promote sustainable urbanization and combat the economic, environmental, energy and safety issues that go with rapid motorization, the Ministry of Transport in China has introduced the “Transit Metropolis” program with a substantive amount of funds devoted to the implementation of the program in local governments. This represents the largest ever central government-led effort addressing transit metropolis development in the world. How has the program been implemented locally? Have the selected demonstration cities followed the same principle or taken comparable measures to implement their version of the transit metropolis? What is their performance? These questions remain unknown in the current literature. This article answers the above questions through a literature review, interviews and comparative case studies in Shenyang and Dalian, two large cities in Liaoning Province. It shows that both cities have successfully achieved the target levels for building a transit metropolis. Similarities between the two cities can be found their absence of any policies on automobile restriction and the presence of enormous efforts in transit network expansion and optimization. Differences lie in the fact that Shenyang has been more conventional in developing the transit metropolis, while Dalian has been more innovative and flexible in policy implementation. When comparing our empirical findings with the experience of creating transit metropolis elsewhere in China and in foreign countries, we find that policies and regulations restricting car use and calming traffic are not necessary conditions for successful transit metropolises; however, the attractiveness of transit infrastructure, combined with aesthetic and well-decorated street network is essential for a modal shift for transit. We also find that the perception on the transit metropolis in China more emphasizes transit service improvement, while the concept in Western countries more focuses on the shift of land use patterns that lean more towards influencing transit behavior.","transit metropolis; transport policy; policy implementation; Shenyang; Dalian; China","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:f422937d-b28c-4345-b8e5-f5b258ffa755","http://resolver.tudelft.nl/uuid:f422937d-b28c-4345-b8e5-f5b258ffa755","Funding sustainable cities: A comparative study of Sino-Singapore Tianjin Eco-City and Shenzhen International Low-Carbon City","Zhan, Changjie (Fuzhou University); de Jong, W.M. (TU Delft Organisation & Governance; Fudan University; Erasmus Universiteit Rotterdam); de Bruijn, J.A. (TU Delft Organisation & Governance)","","2018","China has gone through a rapid process of urbanization, but this has come along with serious environmental problems. Therefore, it has started to develop various eco-cities, low-carbon cities, and other types of sustainable cities. The massive launch of these sustainable initiatives, as well as the higher cost of these projects, requires the Chinese government to invest large sums of money. What financial toolkits can be employed to fund this construction has become a critical issue. Against this backdrop, the authors have selected Sino-Singapore Tianjin Eco-city (SSTEC) and Shenzhen International Low-Carbon City (ILCC) and compared how they finance their construction. Both are thus far considered to be successful cases. The results show that the two cases differ from each other in two key aspects. First, ILCC has developed a model with less financial and other supports from the Chinese central government and foreign governments than SSTEC, and, hence, may be more valuable as a source of inspiration for other similar projects for which political support at the national level is not always available. Second, by issuing bonds in the international capital market, SSTEC singles itself out among various sustainable initiatives in China, while planning the village area as a whole and the metro plus property model are distinct practices in ILCC. In the end, the authors present a generic financing model that considers not only economic returns but also social and environmental impacts to facilitate future initiatives to finance in more structural ways.","Bonds; Finance; Public private partnerships; Shenzhen; Sustainable cities; Tianjin","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:628f36a9-9351-4610-b1c5-13ccbbf3f650","http://resolver.tudelft.nl/uuid:628f36a9-9351-4610-b1c5-13ccbbf3f650","Acoustic Characterization of the CLINIcell for Ultrasound Contrast Agent Studies","Beekers, D.I. (Erasmus MC); van Rooij, Tom (Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Acoustical Wavefield Imaging); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging); Verweij, M.D. (TU Delft ImPhys/Acoustical Wavefield Imaging); Kooiman, Klazina (Erasmus MC)","","2018","Ultrasound contrast agents consist of gas-filled coated microbubbles that oscillate upon ultrasound insonification. Their characteristic oscillatory response provides contrast enhancement for imaging and has the potential to locally enhance drug delivery. Since microbubble response depends on the local acoustic pressure, an ultrasound compatible chamber is needed to study their behavior and the underlying drug delivery pathways. In this study, we determined the amplitude of the acoustic pressure in the CLINIcell, an optically transparent chamber suitable for cell culture. The pressure field was characterized based on microbubble response recorded using the Brandaris 128 ultra-high speed camera and an iterative processing method. The results were compared to a control experiment performed in an OptiCell, which is conventionally used in microbubble studies. Microbubbles in the CLINIcell responded in a controlled manner, comparable to those in the OptiCell. For frequencies from 1 to 4 MHz, the mean pressure amplitude was -5.4 dB with respect to the externally applied field. The predictable ultrasound pressure demonstrates the potential of the CLINIcell as an optical, ultrasound, and cell culture compatible device to study microbubble oscillation behavior and ultrasound-mediated drug delivery.","Acoustic characterization; Acoustics; Biomedical optical imaging; Drug delivery; drug delivery; Integrated optics; Optical sensors; Optical variables control; ultra-high speed imaging; Ultrasonic imaging; ultrasound contrast agents","en","journal article","","","","","","","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:90b14100-9e0b-4210-9389-3862bdd8b91d","http://resolver.tudelft.nl/uuid:90b14100-9e0b-4210-9389-3862bdd8b91d","A multimodal transport chain choice model for container transport","de Bok, M.A. (TU Delft Transport and Planning; Significance); de Jong, Gerard (Significance; ITS Leeds); Tavasszy, Lorant (TU Delft Transport and Planning; TU Delft Transport and Logistics); Van Meijeren, Jaco (TNO); Davydenko, Igor (TNO); Benjamins, Michiel (Demis); Groot, Noortje (Ministry of Infrastructure and the Environment); Miete, Onno (Ministry of Infrastructure and the Environment); Van den Berg, Monique (Ministry of Infrastructure and the Environment)","","2018","A large part of freight transport movements are part of a multimodal transport chain, in particular for port-related containerized transport flows. Because data of multimodal transports are unavailable it is challenging to develop a multimodal transport chain models. This paper describes the development of a new module for multimodal transport chains for modelling container transport within the Dutch strategic freight transport model “BasGoed”. The choice model distinguishes unimodal, bi-modal or tri-modal transport chains, depending on whether the transport chain is port-related. A direct road chain is available between each production and consumption combination; direct barge or rail transport is only available between seaports. A route enumeration module generates a choice set for each observed uni- or multimodal container transport. Since no directly observed PC data are available, a synthetic dataset was constructed with container flows between locations of production and consumption, using uni-modal observed transport data. Main assumption is that each container transported by rail or barge requires a road leg at the side of destination and/or origin, to complete the multimodal transport chain. Discrete choice models were estimated with different model structures. The best choice model that was found was a multinomial logit model, segmented by port dependency. The results show that a choice model can be estimated with significant parameters, and with plausible model sensitivities.","Freight transport demand models; multi modal freight transport; The Netherlands","en","journal article","","","","","","","","","","","Transport and Planning","","",""
"uuid:d08d758f-04c1-4240-89c3-7ab86658fe6e","http://resolver.tudelft.nl/uuid:d08d758f-04c1-4240-89c3-7ab86658fe6e","Single-crystal Pt-decorated WO3 ultrathin films: a platform for sub-ppm hydrogen sensing at room temperature","Mattoni, G. (TU Delft QN/Caviglia Lab; Kavli institute of nanoscience Delft); de Jong, B.W.A. (TU Delft Applied Sciences; Kavli institute of nanoscience Delft); Manca, N. (TU Delft QN/Caviglia Lab; Kavli institute of nanoscience Delft); Tomellini, M. (University of Rome Tor Vergata); Caviglia, A. (TU Delft QN/Caviglia Lab; Kavli institute of nanoscience Delft)","","2018","Hydrogen-related technologies are rapidly developing, driven by the necessity of efficient and high-density energy storage. This poses new challenges to the detection of dangerous gases, in particular the realization of cheap, sensitive, and fast hydrogen sensors. Several materials are being studied for this application, but most present critical bottlenecks, such as high operational temperature, low sensitivity, slow response time, and/or complex fabrication procedures. Here, we demonstrate that WO3 in the form of single-crystal, ultrathin films with a Pt catalyst allows high-performance sensing of H2 gas at room temperature. Thanks to the high electrical resistance in the pristine state, this material is able to detect hydrogen concentrations down to 1 ppm near room temperature. Moreover, the high surface-to-volume ratio of WO3 ultrathin films determines fast sensor response and recovery, with characteristic times as low as 1 s when the concentration exceeds 100 ppm. By modeling the hydrogen (de)intercalation dynamics with a kinetic model, we extract the energy barriers of the relevant processes and relate the doping mechanism to the formation of oxygen vacancies. Our results reveal the potential of single-crystal WO3 ultrath","hydrogen sensing; kinetics of intercalcalation and deintercalcalation; room temperature gas detection; ultrathin films; WO3 single crystals","en","journal article","","","","","","","","","Applied Sciences","","QN/Caviglia Lab","","",""
"uuid:99aa7b70-eae9-42fe-90c6-4a44ed2c7cee","http://resolver.tudelft.nl/uuid:99aa7b70-eae9-42fe-90c6-4a44ed2c7cee","The Governance of Risks in Ridesharing: A Revelatory Case from Singapore","Li, Yanwei (Nanjing Normal University); Taeihagh, Araz (National University of Singapore); de Jong, W.M. (TU Delft Organisation & Governance; Fudan University)","","2018","Recently we have witnessed the worldwide adoption of many different types of innovative technologies, such as crowdsourcing, ridesharing, open and big data, aiming at delivering public services more efficiently and effectively. Among them, ridesharing has received substantial attention from decision-makers around the world. Because of the multitude of currently understood or potentially unknown risks associated with ridesharing (unemployment, insurance, information privacy, and environmental risk), governments in different countries apply different strategies to address such risks. Some governments prohibit the adoption of ridesharing altogether, while other governments promote it. In this article, we address the question of how risks involved in ridesharing are governed over time. We present an in-depth single case study on Singapore and examine how the Singaporean government has addressed risks in ridesharing over time. The Singaporean government has a strong ambition to become an innovation hub, and many innovative technologies have been adopted and promoted to that end. At the same time, decision-makers in Singapore are reputed for their proactive style of social governance. The example of Singapore can be regarded as a revelatory case study, helping us further to explore governance practices in other countries.","Case study; Governance; Innovative technologies; Ridesharing; Risk; Singapore; Transport","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:e63e0684-9ba0-456e-9f65-13c926e45abb","http://resolver.tudelft.nl/uuid:e63e0684-9ba0-456e-9f65-13c926e45abb","Transient modelling of rotating and stationary cylindrical heat pipes: An engineering model","Çelik, M. (TU Delft Energy Technology); Paulussen, Geert (Tata Steel); van Erp, Dennis (Tata Steel); de Jong, W. (TU Delft Large Scale Energy Storage); Boersma, B.J. (TU Delft Process and Energy; TU Delft Energy Technology)","","2018","Rotating wickless and stationary capillary cylindrical heat pipes are widely used heat transfer devices. Transient behavior of such heat pipes has been investigated numerically with computational fluid dynamics and lumped parameter models. In this paper, the advantages of both methods are combined into a novel engineering model that is low in computational cost but still accurate and rich in the details it provides. The model describes the interior dynamics of the heat pipe with a 2D representation of a cylindrical heat pipe. Liquid and vapor volumes are coarsely meshed in the axial direction. The cells are allowed to change in size in the radial direction during simulation. This allows for tracking the liquid/vapor interface without having to implement fine meshing. The model includes the equations for mass, momentum and energy and is applicable to both rotating and stationary heat pipes. The predictions of the model are validated with other experimental, numerical, and analytical works having an average deviation of less than 4%. The effects of various parameters on the system are explored. The presented model is suitable for the simulation of heat pipe systems in which both the level of detail and the computational cost are crucial factors.","Capillary heat pipe; Engineering model; Rotating heat pipe; Transient modelling","en","journal article","","","","","","","","","","Process and Energy","Energy Technology","","",""
"uuid:0f5c25f0-86ed-40cb-8012-33ae6c835e15","http://resolver.tudelft.nl/uuid:0f5c25f0-86ed-40cb-8012-33ae6c835e15","Frame-based Programming, Stream-Based Processing for Medical Image Processing Applications","Hoozemans, J.J. (TU Delft Computer Engineering); de Jong, Rob (Philips Healthcare Nederland); van der Vlugt, Steven (Philips Healthcare Nederland); van Straten, J. (TU Delft Computer Engineering); Elango, Uttam Kumar (Student TU Delft); Al-Ars, Z. (TU Delft Computer Engineering)","","2019","This paper presents and evaluates an approach to deploy image and video processing pipelines that are developed frame-oriented on a hardware platform that is stream-oriented, such as an FPGA. First, this calls for a specialized streaming memory hierarchy and accompanying software framework that transparently moves image segments between stages in the image processing pipeline. Second, we use softcore VLIW processors, that are targetable by a C compiler and have hardware debugging capabilities, to evaluate and debug the software before moving to a High-Level Synthesis flow. The algorithm development phase, including debugging and optimizing on the target platform, is often a very time consuming step in the development of a new product. Our proposed platform allows both software developers and hardware designers to test iterations in a matter of seconds (compilation time) instead of hours (synthesis or circuit simulation time).","FPGA; Image processing; Medical imaging","en","journal article","","","","","","","","","","","Computer Engineering","","",""
"uuid:48959287-f003-48a9-bfde-8d50a96aa250","http://resolver.tudelft.nl/uuid:48959287-f003-48a9-bfde-8d50a96aa250","A nitride-based epitaxial surface layer formed by ammonia treatment of silicene-terminated ZrB2","Wiggers, F. B. (University of Twente); Bui, H.V. (University of Twente); Friedlein, R. (Meyer Burger (Germany) AG); Yamada-Takamura, Y. (Japan Advanced Institute of Science and Technology); Schmitz, J.E.J. (TU Delft Electrical Engineering, Mathematics and Computer Science; University of Twente); Kovalgin, A. Y. (University of Twente); de Jong, M (University of Twente)","","2016","We present a method for the formation of an epitaxial surface layer involving B, N, and Si atoms on a ZrB2(0001) thin film on Si(111). It has the potential to be an insulating growth template for 2D semiconductors. The chemical reaction of NH3 molecules with the silicene-terminated ZrB2 surface was characterized by synchrotron-based, high-resolution core-level photoelectron spectroscopy and low-energy electron diffraction. In particular, the dissociative chemisorption of NH3 at 400 °C leads to surface nitridation, and subsequent annealing up to 830 °C results in a solid phase reaction with the ZrB2 subsurface layers. In this way, a new nitride-based epitaxial surface layer is formed with hexagonal symmetry and a single in-plane crystal orientation.","Epitaxy; Photons; Semiconductor surfaces; Insulator surfaces; Nitridation","en","journal article","","","","","","","","2017-04-05","Electrical Engineering, Mathematics and Computer Science","","","","",""
"uuid:d283eaab-2f21-4a9b-a75b-d9c3bf7e6ef3","http://resolver.tudelft.nl/uuid:d283eaab-2f21-4a9b-a75b-d9c3bf7e6ef3","Radiolabeling polymeric micelles for in vivo evaluation: a novel, fast, and facile method","Laan, A.C. (TU Delft RST/Applied Radiation & Isotopes); Santini, Costanza (Erasmus MC); Jennings, Laurence (Institut Charles Sadron); de Jong, Marion (Erasmus MC); Bernsen, Monique R. (Erasmus MC); Denkova, A.G. (TU Delft RST/Applied Radiation & Isotopes)","","2016","Background: Single photon emission computed tomography (SPECT) is an indispensable tool in the determination of the in vivo fate of polymeric micelles. However, for this purpose, the micelles need to be radiolabeled, and almost all radiolabeling procedures published to date involve the conjugation of a chelating agent to the constituting polymer, which could actually affect their biodistribution. In this paper, we report a new facile method for radiolabeling polystyrene-b-poly(ethylene oxide) diblock copolymer micelles without the necessity of any chemical modification. Instead, we entrap the radiolabel (i.e., 111In) in the micellar core during the formation of the micelles by using tropolone as lipophilic ligand. Methods: Micelles were prepared by emulsifying a polymer solution in chloroform with a buffer containing 111In and lipophilic ligand tropolone, by stirring for about 2 h. The produced micelles were physically characterized by means of dynamic light scattering and transmission electron microscopy. The biological properties of the radiolabeled micelles were determined by means of in vivo and ex vivo evaluation. SPECT analysis was done on Balb/c-nu mice, after administration of 1 mg micelles containing 22 MBq of 111In. SPECT images were obtained over 24 h. Biodistribution of the micelles was assessed also ex vivo. Results: The radiolabeling method is robust and reproducible with constant radiolabeling efficiency (~30 %) even at indium concentrations that are much higher than the necessary for in vivo studies, and the radiolabel retention is more than 80 % in mouse serum at 48 h. Radiolabeled micelles having hydrodynamic radius of 97 ± 13 nm have been successfully evaluated in vivo and ex vivo in non-tumor-bearing mice, revealing significant blood circulation up to at least 24 h post injection, with low accumulation in most organs except for the liver and spleen, which are the natural organs for clearance of nanoparticles. Conclusions: An easy and robust radiolabeling method has been developed, and its applicability is demonstrated in animal studies, showing its value for future investigation of polymeric micelles as nanocarriers in tumor-bearing mice.","Amphiphilic diblock copolymers; Polymeric micelles; Radiolabeling; SPECT","en","journal article","","","","","","","","","","","RST/Applied Radiation & Isotopes","","",""
"uuid:df467c54-bab6-4f4a-867e-24f1212cb5c6","http://resolver.tudelft.nl/uuid:df467c54-bab6-4f4a-867e-24f1212cb5c6","How can the Gradual Development of More Sustainable Energy Systems Be Integrated in Urban Planning in China?","Wennersten, Ronald; Sun, Q; de Jong, W.M. (TU Delft Organisation & Governance)","","2016","Great efforts have been made in China to reduce coal consumption over the last decade. However, the energy transition to more sustainable energy systems will be gradual and take a longer time than expected. This paper discusses how sustainable development of energy systems on the local level can be gradually achieved. A challenge will be to develop smaller scale projects on the local level where participatory planning processes with cross sectoral planning can be implemented. Another challenge is to bring transdisciplinary academic research closer to the practice","Sustainable Development; Sustainable Development; Sustainable Energy Systems; Urban Planning","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:e1d3a63b-8aed-45d9-9247-e13e7c5d50f0","http://resolver.tudelft.nl/uuid:e1d3a63b-8aed-45d9-9247-e13e7c5d50f0","Three-dimensional analysis of shape variations and symmetry of the fibula, tibia, calcaneus and talus","Tümer, N. (TU Delft Biomaterials & Tissue Biomechanics); Arbabi, V. (TU Delft Biomaterials & Tissue Biomechanics; University Medical Center Utrecht; University of Birjand); Gielis, Willem Paul (University Medical Center Utrecht); de Jong, Pim A. (University Medical Center Utrecht); Weinans, Harrie (TU Delft Biomaterials & Tissue Biomechanics; University Medical Center Utrecht); Tuijthof, Gabrielle J.M. (Universiteit van Amsterdam; Zuyd University of Applied Sciences); Zadpoor, A.A. (TU Delft Biomaterials & Tissue Biomechanics)","","2019","The bones forming the talocrural joint (TCJ) and subtalar joint (STJ) are often assumed to be bilaterally symmetric. Therefore, the contralateral limb (i.e. the fibula, tibia, calcaneus and talus) is used as a template or an intra-subject control in clinical and research practice. However, the validity of the symmetry assumption is controversial, because insufficient information is available on the shape variations and bilateral (a)symmetry of the fibula, tibia, calcaneus and talus. Using three-dimensional spatially dense sampled representations of bone shapes extracted from bilateral computed tomography scans of 66 individuals (55 male, mean age: 61 ± 10 years; 11 female, mean age: 53 ± 15 years), we analyzed whether: (i) similar shape patterns exist in the left and right bones of the same type; (ii) gender has an effect on bone shape variations; (iii) intra-subject shape variation is smaller than that of inter-subject for a given shape variance direction. For the first set of analyses, all left and right instances of the same type of bone were considered as two separate groups, and statistically compared with each other on multiple aspects including group location (central tendency), variance-covariance scale (dispersion) and orientation (covariance structure) using distance-based permutational tests. For the second and third sets of analyses, all left and right bones of the same type were pooled into one group, and shape variations in the TCJ and STJ bones were extracted using principal component analysis. The effects of gender on age-adjusted bone shape differences were assessed using an analysis of covariance. Moreover, intra-class correlation was employed to evaluate intra- and inter-subject bone shape variations. For each bone type, both sides had similar shape patterns (Ppermutational-values > 0.05). After Bonferroni adjustment, gender led to shape differences, which were mainly in the lateral and medial condyles of the tibia (P = 0.003), the length and height of the calcaneus (P < 0.001), the posterior and anterior talar articular surfaces of the calcaneus (P = 0.001), and in the posterior aspect of the talus (P = 0.001). Intra-subject shape variations in the tibial tuberosity together with the diameter of the tibia, and the curvature of the fibula shaft and the diameter of the fibula were as high as those of inter-subject. This result suggests that the shape symmetry assumption could be violated for some specific shape variations in the fibula and tibia.","bilateral symmetry; calcaneus; fibula; subtalar joint; talocrural joint; talus; tibia","en","journal article","","","","","","","","","","","Biomaterials & Tissue Biomechanics","","",""
"uuid:caf0c0fd-bafd-4872-b56f-ae22843e0bfe","http://resolver.tudelft.nl/uuid:caf0c0fd-bafd-4872-b56f-ae22843e0bfe","Coherent mechanical noise cancellation and cooperativity competition in optomechanical arrays","de Jong, M.H.J. (TU Delft QN/Groeblacher Lab; TU Delft Dynamics of Micro and Nano Systems; Kavli institute of nanoscience Delft); Li, J. (TU Delft QN/Groeblacher Lab; Zhejiang University; Kavli institute of nanoscience Delft); Gartner, C.M. (TU Delft QN/Groeblacher Lab; Kavli institute of nanoscience Delft); Norte, R.A. (TU Delft Dynamics of Micro and Nano Systems); Groeblacher, S. (TU Delft QN/Groeblacher Lab; Kavli institute of nanoscience Delft)","","2022","Studying the interplay between multiple coupled mechanical resonators is a promising new direction in the field of optomechanics. Understanding the dynamics of the interaction can lead to rich new effects, such as enhanced coupling and multi-body physics. In particular, multi-resonator optomechanical systems allow for distinct dynamical effects due to the optical cavity coherently coupling mechanical resonators. Here, we study the mechanical response of two SiN membranes and a single optical mode, and find that the cavity induces a time delay between the local and cavity-transduced thermal noises experienced by the resonators. This results in an optomechanical phase lag that causes destructive interference, cancelling the mechanical thermal noise by up to 20 dB in a controllable fashion and matching our theoretical expectation. Based on the effective coupling between membranes, we further propose, derive, and measure a collective effect, cooperativity competition on mechanical dissipation, whereby the linewidth of one resonator depends on the coupling efficiency (cooperativity) of the other resonator.","","en","journal article","","","","","","","","","","","QN/Groeblacher Lab","","",""
"uuid:dca5afec-3b08-46fa-ab09-d6081cebab7a","http://resolver.tudelft.nl/uuid:dca5afec-3b08-46fa-ab09-d6081cebab7a","Hydroxyl Ethyl Starch (HES) Preserves Intrarenal Microcirculatory Perfusion Shown by Contrast-Enhanced Ultrasound (Ceus), and Renal Function in a Severe Hemodilution Model in Pigs","Ergin, Bülent (Erasmus MC); van Rooij, Tom (Erasmus MC); Lima, Alexandre (Erasmus MC); Ince, Yasin (Erasmus MC); Specht, Patricia A.C. (Erasmus MC); Mik, E.G. (Erasmus MC); Kooiman, Klazina (Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Ince, Can (Erasmus MC)","","2022","Acute normovolemic hemodilution (ANH) is associated with low oxygen carrying capacity of blood and purposed to cause renal injury in perioperative setting. It is best accomplished in a perioperative setting by a colloid such as hydroxyl ethyl starch (HES) due its capacity to fill the vascular compartment and maintain colloidal pressure. However, alterations of intra renal microvascular perfusion, flow and its effects on renal function and damage during ANH has not been sufficiently clarified. Based on the extensive use of HES in the perioperative setting we tested the hypothesis that the use of HES during ANH is able to perfuse the kidney microcirculation adequately without causing renal dysfunction and injury in pigs. Hemodilution (n = 8) was performed by stepwise replacing blood with HES to hematocrit (Hct) levels of 20% (T1), 15% (T2), and 10% (T3). Seven control animals were investigated. Systemic and renal hemodynamics were monitored. Renal microcirculatory perfusion was visualized and quantified using contrast-enhanced ultrasound (CEUS) and laser speckle imaging (LSI). In addition, sublingual microcirculation was measured by handheld vital microscopy (HVM). Intrarenal mean transit time of ultrasound contrast agent (IRMTT-CEUS) was reduced in the renal cortex at Hct 10% in comparison to control at T3 (1.4 ± 0.6 vs. 2.2 ± 0.7 seconds, respectively, P < 0.05). Although renal function was preserved, the serum neutrophil gelatinase-associated lipocalin (NGAL) levels was higher at Hct 10% (0.033 ± 0.004 pg/μg protein) in comparison to control at T3 (0.021 ± 0.002 pg/μg protein. A mild correlation between CO and IRMTT (renal RBC velocity) (r -0.53; P = 0.001) and CO and NGAL levels (r 0.66; P = 0.001) was also found. Our results show that HES induced ANH is associated with a preserved intra renal blood volume, perfusion, and function in the clinical range of Hct (<15%). However, at severely low Hct (10%) ANH was associated with renal injury as indicated by increased NGAL levels. Changes in renal microcirculatory flow (CEUS and LSI) followed those seen in the sublingual microcirculation measured with HVM.","Acute normovolemic hemodilution; contrast-enhanced ultrasound; hydroxyethyl starch; renal microcirculation; sublingual microcirculation","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2023-07-01","","","ImPhys/Medical Imaging","","",""
"uuid:3ef12fc1-f8e0-473e-a7c8-06357e54061a","http://resolver.tudelft.nl/uuid:3ef12fc1-f8e0-473e-a7c8-06357e54061a","How Do Neural Networks Estimate Optical Flow A Neuropsychology-Inspired Study","de Jong, D.B. (TU Delft Education AE); Paredes-Vallés, Federico (TU Delft Control & Simulation); de Croon, G.C.H.E. (TU Delft Control & Simulation)","","2022","End-to-end trained convolutional neural networks have led to a breakthrough in optical flow estimation. The most recent advances focus on improving the optical flow estimation by improving the architecture and setting a new benchmark on the publicly available MPI-Sintel dataset. Instead, in this article, we investigate how deep neural networks estimate optical flow. A better understanding of how these networks function is important for (i) assessing their generalization capabilities to unseen inputs, and (ii) suggesting changes to improve their performance. For our investigation, we focus on FlowNetS, as it is the prototype of an encoder-decoder neural network for optical flow estimation. Furthermore, we use a filter identification method that has played a major role in uncovering the motion filters present in animal brains in neuropsychological research. The method shows that the filters in the deepest layer of FlowNetS are sensitive to a variety of motion patterns. Not only do we find translation filters, as demonstrated in animal brains, but thanks to the easier measurements in artificial neural networks, we even unveil dilation, rotation, and occlusion filters. Furthermore, we find similarities in the refinement part of the network and the perceptual filling-in process which occurs in the mammal primary visual cortex.","Biomedical optical imaging; convolutional neural networks; Estimation; Gabor filters; neuropsychology; Optical computing; Optical fiber networks; Optical flow; Optical imaging; Optical sensors; Visualization","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2023-07-01","","","Education AE","","",""
"uuid:27985217-0e99-4511-9d48-2f65eaf2e70c","http://resolver.tudelft.nl/uuid:27985217-0e99-4511-9d48-2f65eaf2e70c","Refraction-Corrected Transcranial Ultrasound Imaging through the Human Temporal Window using a Single Probe","Mozaffarzadeh, M. (TU Delft ImPhys/Medical Imaging); Verschuur, D.J. (TU Delft ImPhys/Computational Imaging); Verweij, M.D. (TU Delft ImPhys/Medical Imaging); Daeichin, V. (TU Delft ImPhys/Medical Imaging); de Jong, N. (TU Delft ImPhys/Medical Imaging); Renaud, G.G.J. (TU Delft ImPhys/Medical Imaging)","","2022","Transcranial ultrasound imaging (TUI) is a diagnostic modality with numerous applications, but unfortunately, it is hindered by phase aberration caused by the skull. In this article, we propose to reconstruct a transcranial B-mode image with a refraction-corrected synthetic aperture imaging (SAI) scheme. First, the compressional sound velocity of the aberrator (i.e., the skull) is estimated using the bidirectional headwave technique. The medium is described with four layers (i.e., lens, water, skull, and water), and a fast marching method calculates the travel times between individual array elements and image pixels. Finally, a delay-and-sum algorithm is used for image reconstruction with coherent compounding. The point spread function (PSF) in a wire phantom image and reconstructed with the conventional technique (using a constant sound speed throughout the medium), and the proposed method was quantified with numerical synthetic data and experiments with a bone-mimicking plate and a human skull, compared with the PSF achieved in a ground truth image of the medium without the aberrator (i.e., the bone plate or skull). A phased-array transducer (P4-1, ATL/Philips, 2.5 MHz, 96 elements, pitch $=$ 0.295 mm) was used for the experiments. The results with the synthetic signals, the bone-mimicking plate, and the skull indicated that the proposed method reconstructs the scatterers with an average lateral/axial localization error of 0.06/0.14 mm, 0.11/0.13 mm, and 1.0/0.32 mm, respectively. With the human skull, an average contrast ratio (CR) and full-width-half-maximum (FWHM) of 37.1 dB and 1.75 mm were obtained with the proposed approach, respectively. This corresponds to an improvement of CR and FWHM by 7.1 dB and 36% compared with the conventional method, respectively. These numbers were 12.7 dB and 41% with the bone-mimicking plate.","Transcranial ultrasound imaging; Adaptive beamforming; Phase aberration correction; Head waves; Temporal bone; Bones; Image coding; Image reconstruction; Imaging; Probes; Skull; Ultrasonic imaging","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2022-07-31","","","ImPhys/Medical Imaging","","",""
"uuid:42816a83-4ad2-44c6-a030-8dc8b35066fa","http://resolver.tudelft.nl/uuid:42816a83-4ad2-44c6-a030-8dc8b35066fa","Removal of Antibiotic Resistance From Municipal Secondary Effluents by Ozone-Activated Carbon Filtration","Spit, T.P.M. (TU Delft Support Water Management; Witteveen+Bos); van der Hoek, J.P. (TU Delft Sanitary Engineering; Witteveen+Bos); de Jong, Coen (Witteveen+Bos); van Halem, D. (TU Delft Sanitary Engineering); de Kreuk, M.K. (TU Delft Sanitary Engineering); Bicudo, Bruno (TU Delft Sanitary Engineering)","","2022","At wastewater treatment plants (WWTPs), additional steps are introduced for removal of organic micropollutants (OMPs) from the treated effluents, especially pharmaceutical residues. At the same time, a new concern is emerging: antibiotic resistance (AR). This research studied the effect of ozonation, coagulation and granular activated carbon (GAC) filtration applied as tertiary treatment for the removal of OMPs and nutrients, on AR removal. Bacterial culture methods in selective media were used to screen for four different microorganisms: two faecal indicators (Escherichia coli and Enterococci) as antibiotic sensitive bacteria (ASB), and a resistant strain of each of these bacteria, namely Extended-Spectrum Beta-lactamase producing E. coli (ESBL-E.coli) and Vancomycin Resistant Enterococci (VRE) as antibiotic resistant bacteria (ARB). At laboratory scale, ozonation experiments (ozone dose 0.4–0.6 g O 3/g DOC) and coagulation experiments using Polyaluminum chloride (PAX-214) and FeCl 3 (coagulant dose 0.004–1 mM/L) were performed using secondary effluent from two municipal WWTPs. In addition in a pilot plant and full-scale plant ozonation (ozone dose 0.4 g O 3/g DOC) and GAC filtration (empty bed contact time 15 min) were studied for AR removal. No significant differences were found between ARB and ASB removal for coagulation and ozonation which could indicate that ASB can be used as an initial proxy for ARB removal for these technologies. In the laboratory experiments, ozonation and coagulation showed a good removal of both ARB and ASB. However, the doses needed to reach 2–3 log removal were a factor 2.5–4 (ozonation) and 250 (coagulation) higher than applied for OMP removal (by ozonation) and phosphorus (P) removal (by coagulation). In the GAC filters, the risk of ARB enhancement occurred, especially in filters with a matured biology. Although these bacteria are not necessarily directly harmful, they can pass down their resistance to pathogenic bacteria via horizontal gene transfer.","antibiotic resistance; ozon; activated carbon; municipal secondary effluent; tertiary treatment; coagulation","en","journal article","","","","","","","","","","","Support Water Management","","",""
"uuid:450731eb-345c-42cf-9082-25962fd26744","http://resolver.tudelft.nl/uuid:450731eb-345c-42cf-9082-25962fd26744","Independent Component Analysis Filter for Small Vessel Contrast Imaging During Fast Tissue Motion","Wahyulaksana, G. (Erasmus MC); Wei, Luxi (Erasmus MC); Schoormans, Jasper (Erasmus MC); Voorneveld, J.D. (Erasmus MC); van der Steen, A.F.W. (Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Vos, H.J. (TU Delft ImPhys/Medical Imaging; Erasmus MC)","","2022","Suppressing tissue clutter is an essential step in blood flow estimation and visualization, even when using ultrasound contrast agents. Blind source separation (BSS)-based clutter filter for high-framerate ultrasound imaging has been reported to perform better in tissue clutter suppression than the conventional frequency-based wall filter and nonlinear contrast pulsing schemes. The most notable BSS technique, singular value decomposition (SVD) has shown compelling results in cases of slow tissue motion. However, its performance degrades when the tissue motion is faster than the blood flow speed, conditions that are likely to occur when imaging the small vessels, such as in the myocardium. Independent component analysis (ICA) is another BSS technique that has been implemented as a clutter filter in the spatiotemporal domain. Instead, we propose to implement ICA in the spatial domain where motion should have less impact. In this work, we propose a clutter filter with the combination of SVD and ICA to improve the contrast-to-background ratio (CBR) in cases where tissue velocity is significantly faster than the flow speed. In an in vitro study, the range of fast tissue motion velocity was 5-25 mm/s and the range of flow speed was 1-12 mm/s. Our results show that the combination of ICA and SVD yields 7-10 dB higher CBR than SVD alone, especially in the tissue high-velocity range. The improvement is crucial for cardiac imaging where relatively fast myocardial motions are expected.","blind source separation; Clutter; clutter filter; Contrast-enhanced ultrasound; Imaging; Information filters; Power harmonic filters; Probes; slow blood flow; Spatiotemporal phenomena; tissue motion; Ultrasonic imaging","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:d0947a9c-1a30-41ab-9d5a-34cbad4c6371","http://resolver.tudelft.nl/uuid:d0947a9c-1a30-41ab-9d5a-34cbad4c6371","An iterative method to evaluate one-dimensional pulsed nonlinear elastic wavefields and mixing of elastic waves in solids","Selvam, S. (TU Delft ImPhys/Medical Imaging); Volker, Arno; van Neer, P.L.M.J. (TNO); de Jong, N. (TU Delft ImPhys/Medical Imaging); Verweij, M.D. (TU Delft ImPhys/Medical Imaging)","","2022","Over the last 15 years, literature on nondestructive testing has shown that the generation of higher harmonics and nonlinear mixing of waves could be used to obtain the nonlinearity parameters of an elastic medium and thereby gather information about its state, e.g., aging and fatigue. To design ultrasound measurement setups based on these phenomena, efficient numerical modeling tools are needed. In this paper, the iterative nonlinear contrast source method for numerical modeling of nonlinear acoustic waves is extended to the one-dimensional elastic case. In particular, nonlinear mixing of two collinear bulk waves (one compressional, one shear) in a homogeneous, isotropic medium is considered, taking into account its third-order elastic constants ( A, B, and C). The obtained results for nonlinear propagation are in good agreement with a benchmark solution based on the modified Burgers equation. The results for the resonant waves that are caused by the one-way and two-way mixing of primary waves are in quantitative agreement with the results in the literature [Chen, Tang, Zhao, Jacobs, and Qu, J. Acoust. Soc. Am. 136(5), 2389-2404 (2014)]. The contrast source approach allows the identification of the propagating and evanescent components of the scattered wavefield in the wavenumber-frequency domain, which provides physical insight into the mixing process and explains the propagation direction of the resonant wave.","","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2023-07-01","","","ImPhys/Medical Imaging","","",""
"uuid:2aaa3718-8db9-4178-a8fc-d788e0b858f6","http://resolver.tudelft.nl/uuid:2aaa3718-8db9-4178-a8fc-d788e0b858f6","Acoustic Modulation Enables Proton Detection with Nanodroplets at Body Temperature","Heymans, Sophie V. (Katholieke Universiteit Leuven; Erasmus MC); Collado Lara, G. (Erasmus MC); Rovituso, M. (Holland Particle Therapy Centre); Vos, H.J. (TU Delft ImPhys/Medical Imaging; Erasmus MC); D'hooge, Jan (Katholieke Universiteit Leuven); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Van Den Abeele, Koen (Katholieke Universiteit Leuven)","","2022","Superheated nanodroplet (ND) vaporization by proton radiation was recently demonstrated, opening the door to ultrasound-based in vivo proton range verification. However, at body temperature and physiological pressures, perfluorobutane nanodroplets (PFB-NDs), which offer a good compromise between stability and radiation sensitivity, are not directly sensitive to primary protons. Instead, they are vaporized by infrequent secondary particles, which limits the precision for range verification. The radiation-induced vaporization threshold (i.e., sensitization threshold) can be reduced by lowering the pressure in the droplet such that ND vaporization by primary protons can occur. Here, we propose to use an acoustic field to modulate the pressure, intermittently lowering the proton sensitization threshold of PFB-NDs during the rarefactional phase of the ultrasound wave. Simultaneous proton irradiation and sonication with a 1.1 MHz focused transducer, using increasing peak negative pressures (PNPs), were applied on a dilution of PFB-NDs flowing in a tube, while vaporization was acoustically monitored with a linear array. Sensitization to primary protons was achieved at temperatures between 29 °C and 40 °C using acoustic PNPs of relatively low amplitude (from 800 to 200 kPa, respectively), while sonication alone did not lead to ND vaporization at those PNPs. Sensitization was also measured at the clinically relevant body temperature (i.e., 37 °C) using a PNP of 400 kPa. These findings confirm that acoustic modulation lowers the sensitization threshold of superheated NDs, enabling a direct proton response at body temperature.","acoustic droplet vaporization; acoustic modulation; Acoustics; In vivo; Liquids; Nanodroplets; proton range verification; proton therapy; Protons; Temperature sensors; Transducers; Ultrasonic imaging; ultrasound contrast agents","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:ec3078f1-c2d3-4413-80d7-d25e9514a7e9","http://resolver.tudelft.nl/uuid:ec3078f1-c2d3-4413-80d7-d25e9514a7e9","Rules for the Governance of Transport and Land use Integration in High-speed Railway Station Areas in China: The Case of Lanzhou","Wang, B. (TU Delft Urban Development Management); Ersoy, A. (TU Delft Urban Development Management); van Bueren, Ellen (TU Delft Management in the Built Environment); de Jong, Martin (Erasmus Universiteit Rotterdam; Fudan University)","","2022","The rapid high-speed railway development in China has faced many institutional challenges for the integrated development of transport and land use in station areas. This paper aims to gain insight into the institutional rules that structure the actors’ interactions and how they influence the integrated development in station areas. The Institutional Analysis and Development framework has been applied to a specific action situation, named Lanzhou West HSR station area in China. The findings from interviews, document analysis, and field visits reveal that Chinese institutional rules obstruct interactions between actors, thereby hampering the integrated development of functions in HSR station areas.","Rules; institutional analysis; integration of transport and land use; high-speed railway; station area","en","journal article","","","","","","","","","","Management in the Built Environment","Urban Development Management","","",""
"uuid:29c8f417-e167-48b5-8cbf-28eb27f57ab4","http://resolver.tudelft.nl/uuid:29c8f417-e167-48b5-8cbf-28eb27f57ab4","Optimization of Microbubble Concentration and Acoustic Pressure for Left Ventricular High Frame Rate EchoPIV in Patients","Voorneveld, J.D. (Erasmus MC); Keijzer, L.B.H. (Erasmus MC); Strachinaru, Mihai (Erasmus MC); Bowen, Daniel J. (Erasmus MC); Mutluer, Ferit O. (Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Ten Cate, Folkert (Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Vos, H.J. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Van den Bosch, Annemien E. (Erasmus MC); Bosch, Johan G. (Erasmus MC)","","2021","High-frame-rate (HFR) echo-particle image velocimetry (echoPIV) is a promising tool for measuring intracardiac blood flow dynamics. In this study, we investigate the optimal ultrasound contrast agent (UCA: SonoVue) infusion rate and acoustic output to use for HFR echoPIV (PRF = 4900 Hz) in the left ventricle (LV) of patients. Three infusion rates (0.3, 0.6, and 1.2 ml/min) and five acoustic output amplitudes (by varying transmit voltage: 5, 10, 15, 20, and 30 V - corresponding to mechanical indices of 0.01, 0.02, 0.03, 0.04, and 0.06 at 60-mm depth) were tested in 20 patients admitted for symptoms of heart failure. We assess the accuracy of HFR echoPIV against pulsed-wave Doppler acquisitions obtained for mitral inflow and aortic outflow. In terms of image quality, the 1.2-ml/min infusion rate provided the highest contrast-to-background ratio (CBR) (3-dB improvement over 0.3 ml/min). The highest acoustic output tested resulted in the lowest CBR. Increased acoustic output also resulted in increased microbubble disruption. For the echoPIV results, the 1.2-ml/min infusion rate provided the best vector quality and accuracy; mid-range acoustic outputs (corresponding to 15-20-V transmit voltages) provided the best agreement with the pulsed-wave Doppler. Overall, the highest infusion rate (1.2 ml/min) and mid-range acoustic output amplitudes provided the best image quality and echoPIV results.","Blood flow imaging; contrast-enhanced ultrasound (CEUS); echo-particle image velocimetry (echoPIV); echocardiography; heart failure; high-frame-rate (HFR) imaging; ultrafast ultrasound imaging; ultrasound velocimetry; vector flow imaging (VFI)","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:bb763701-bbf4-42d9-840a-132767b5ccc3","http://resolver.tudelft.nl/uuid:bb763701-bbf4-42d9-840a-132767b5ccc3","Classification of human activity using radar and video multimodal learning","de Jong, Richard J. (TNO); de Wit, Jacco J.M. (TNO); Uysal, Faruk (TU Delft Microwave Sensing, Signals & Systems)","","2021","In the defence and security domain, camera systems are widely used for surveillance. The major advantage of using camera systems for surveillance is that they provide high‐resolution imagery, which is easy to interpret. However, the use of camera systems and optical imagery has some drawbacks, especially for application in the military domain. In poor lighting conditions, dust or smoke the image quality degrades and, additionally, cameras cannot provide range information too. These drawbacks can be mitigated by exploiting the strengths of radar. Radar performance can be largely maintained during the night, in various weather conditions and in dust and smoke. Moreover, radar provides the distance to detected objects. Since, the strongpoints and weaknesses of radar and camera systems seem complementary, a natural question is: can radar and camera systems learn from each other? Here the potential of radar/video multimodal learning is evaluated for human activity classification. The novelty of this work is the use of radar spectrograms and related video frames for classification with a multimodal neural network. Radar spectrograms and video frames are both two‐dimensional images, but the information they contain is of different nature. This approach was adopted to limit the required preprocessing load, while maintaining the complementary nature of the sensor data.","","en","journal article","","","","","","","","","","","Microwave Sensing, Signals & Systems","","",""
"uuid:3145517c-b402-4adc-89c5-2c1e22c734c9","http://resolver.tudelft.nl/uuid:3145517c-b402-4adc-89c5-2c1e22c734c9","Mapping key features and dimensions of the inclusive city: A systematic bibliometric analysis and literature study","Liang, Danni (Dalian University of Technology); de Jong, Martin (Rotterdam School of Management; Fudan University; Erasmus Universiteit Rotterdam); Schraven, D.F.J. (TU Delft Integral Design & Management); Wang, Lili (Dalian University of Technology)","","2021","Many local governments engaging in sustainable urban development also have a growing interest in becoming inclusive too, brand themselves as such and develop policies to become inclusive cities. However, knowing what exactly this entails and how it can be achieved is not always quite straightforward and requires thorough theoretical and empirical exploration. Consequently, we present a systematic deconstruction of the inclusive city concept in order to develop a better understanding of the main features and dimensions; this is done by means of both a bibliometric analysis and qualitative literature review. The results indicate that inclusiveness is multidimensional and comprised of spatial, social, environmental, economic, and political dimensions in which the characteristics of participation, equity, accessibility and sustainability are sometimes interwoven. Overall, the inclusive city is not merely a precondition for the creation of just space, well-being, and environmental responsibility, but also an opportunity to take stock of interests of stakeholders in cities and to create local public value. The findings have implications for urban policy and practice, more specifically, the clarification of the inclusive city concept and conceptual dimensions will provide significant reference for policymakers and practitioners to make prudent decisions in the process of creating an inclusive city.","Inclusive city; bibliometric analysis; equity; literature review; sustainable urbanization","en","journal article","","","","","","","","","","","Integral Design & Management","","",""
"uuid:e6720ff1-4ec1-4563-9d2e-c1337214dc62","http://resolver.tudelft.nl/uuid:e6720ff1-4ec1-4563-9d2e-c1337214dc62","Measurement of Pipe and Fluid Properties with a Matrix Array-based Ultrasonic Clamp-on Flow Meter","Massaad Mouawad, J.M. (TU Delft ImPhys/Medical Imaging); van Neer, P.L.M.J. (TU Delft ImPhys/Medical Imaging); van Willigen, D.M. (TU Delft Electronic Instrumentation); Sabbadini, A. (TU Delft ImPhys/Medical Imaging); de Jong, N. (TU Delft ImPhys/Medical Imaging); Pertijs, M.A.P. (TU Delft Electronic Instrumentation); Verweij, M.D. (TU Delft ImPhys/Medical Imaging)","","2021","Current ultrasonic clamp-on flow meters consist of a pair of single-element transducers that are carefully positioned before use. This positioning process consists of manually finding the distance between the transducer elements, along the pipe axis, for which maximum signal-to-noise ratio (SNR) is achieved. This distance depends on the sound speed, thickness, and diameter of the pipe and on the sound speed of the liquid. However, these parameters are either known with low accuracy or completely unknown during positioning, making it a manual and troublesome process. Furthermore, even when sensor positioning is done properly, uncertainty about the mentioned parameters, and therefore on the path of the acoustic beams, limits the final accuracy of flow measurements. In this research, we address these issues using an ultrasonic clamp-on flow meter consisting of two matrix arrays, which enables the measurement of pipe and liquid parameters by the flow meter itself. Automatic parameter extraction, combined with the beam-steering capabilities of transducer arrays, yields a sensor capable of compensating for pipe imperfections. Three parameter extraction procedures are presented. In contrast to similar literature, the procedures proposed here do not require that the medium be submerged nor do they require a priori information about it. First, axial Lamb waves are excited along the pipe wall and recorded with one of the arrays. A dispersion curve-fitting algorithm is used to extract bulk sound speeds and wall thickness of the pipe from the measured dispersion curves. Second, circumferential Lamb waves are excited, measured, and corrected for dispersion to extract the pipe diameter. Third, pulse-echo measurements provide the sound speed of the liquid. The effectiveness of the first two procedures has been evaluated using simulated and measured data of stainless steel and aluminum pipes, and the feasibility of the third procedure has been evaluated using simulated data.","Dispersion correction; Lamb waves; matrix transducer; parameter extraction; ultrasound flow meter","en","journal article","","","","","","Accepted Author Manuscript","","","","","ImPhys/Medical Imaging","","",""
"uuid:1989fa30-b9d5-4c99-b634-24f881be428b","http://resolver.tudelft.nl/uuid:1989fa30-b9d5-4c99-b634-24f881be428b","Never landing drone: Autonomous soaring of a unmanned aerial vehicle in front of a moving obstacle","de Jong, Chris P.L. (Student TU Delft); Remes, B.D.W. (TU Delft Control & Simulation); Hwang, S. (TU Delft Control & Simulation); de Wagter, C. (TU Delft Control & Simulation)","","2021","Increasing endurance is a major challenge for battery-powered aerial vehicles. A method is presented which makes use of an updraft around obstacles to decrease the power consumption of a fixed-wing unmanned aerial vehicle. A soaring flight controller has been developed that can autonomously soar while the unmanned aerial vehicle keeps its relative position to that of a moving object. Multiple simulations have been performed to analyse the limitations of the soaring controller under different conditions. The effect of a change in wind velocity and updraft has been analysed. The simulations showed that an increase in updraft decreases the energy consumption of the flight controller. An increase in wind velocity results in a higher updraft requirement, while a decrease in the wind velocity requires less updraft. The simulations achieved sustained flight at 0% throttle. The controller has been validated experimentally using the updraft generated by a moving ship. The practical, autonomous tests reduced the average throttle down to 4.5% in front of a ship. The method presented in this study achieved successful hovering flight using an energy control module for longitudinal positioning.","fixed-wing; flight control; orographic lift; practical tests; simulation; Soaring; updraft","en","journal article","","","","","","","","","","","Control & Simulation","","",""
"uuid:9aefc795-963c-4ce6-95a2-a720bc040401","http://resolver.tudelft.nl/uuid:9aefc795-963c-4ce6-95a2-a720bc040401","Innovation opportunities for academic libraries to support teaching through open education: A case study at TU Delft, the Netherlands","de Jong, M. (TU Delft Education Support Library Education Services); Munnik, M.E. (TU Delft Library Education Services); Will, N.U. (TU Delft Education Support Library Education Services)","","2019","Opportunities for academic libraries to enrich their products and services through facilitating open education (OE) in higher education are presented in an overview of good practices. A case study of open textbook publishing was performed at TU Delft to study how these products and services could stimulate educators to adopt OE. A simplified user acceptance model of innovation was developed and applied to the case study, to study the educator’s mind-set before and after they published an open textbook with the support of the TU Delft Library. Using the insights that were gained from the case study and from good practices of other university libraries, recommendations are presented for professionalizing products and services by academic libraries to facilitate the adoption of OE into educational practice and to develop institutional policies and regulations that support educators with these practices.","Library innovation; OER; open education; open textbooks; user acceptance model","en","journal article","","","","","","","","","","","Education Support Library Education Services","","",""
"uuid:308f9baa-c9e4-46bd-8319-10fb81e0eae1","http://resolver.tudelft.nl/uuid:308f9baa-c9e4-46bd-8319-10fb81e0eae1","A screw based methodology for instantaneous dynamic balance","de Jong, J.J. (University of Twente); van Dijk, J. (University of Twente); Herder, J.L. (TU Delft Precision and Microsystems Engineering; TU Delft Mechatronic Systems Design)","","2019","Fast-moving industrial robots exert large varying reaction forces and moments on their base frame, inducing vibrations, wear and accuracy degeneration. These shaking forces and moments can be eliminated by a specific design of the mass distribution of the robot links, resulting in a dynamically balanced mechanism. Obtaining the conditions for dynamic balance proves to be a hurdle even for simple planar parallel mechanisms due to the required inclusion and inspection of the kinematic relations. In this paper, a screw theory based methodology is presented, which gives and solves the necessary instantaneous dynamic balance conditions for planar and spatial mechanisms in an uniform and geometrical manner. Instantaneous dynamic balance yields a pose in which robot accelerations induce no shaking forces and moments. This is interpreted as an intersection point of multiple reactionless paths. This method is applied to a 2-DOF planar mechanism, named the Fuga I, for which it resulted in two perpendicularly intersecting reactionless paths, intersecting in the middle of the workspace. Experiments on this demonstrator validated the instantaneous dynamic balance by showing a reduction of approximately 95% of the peak-to-peak shaking forces and moments over the intersecting reactionless paths.","Dynamic balance; Experimental validation; Five-bar mechanism; Parallel manipulator; Reactionless path; Screw theory; Spatial mechanisms","en","journal article","","","","","","Accepted Author Manuscript","","2021-08-14","","Precision and Microsystems Engineering","Mechatronic Systems Design","","",""
"uuid:867d7d24-041d-4cc7-b763-9fc8b8cbfd15","http://resolver.tudelft.nl/uuid:867d7d24-041d-4cc7-b763-9fc8b8cbfd15","The heel-induced sway force and yaw moment of a high-speed craft in following regular waves","Bonci, M. (TU Delft Ship Hydromechanics and Structures); de Jong, Pepijn (Maritime Research Institute Netherlands (MARIN)); van Walree, Frans (Maritime Research Institute Netherlands (MARIN)); Renilson, Martin (University of Tasmania); Keuning, J.A. (TU Delft Ship Hydromechanics and Structures); van 't Veer, A.P. (TU Delft Marine and Transport Technology)","","2020","The coupling between heel and the loads in the horizontal plane is usually neglected in manoeuvrability studies. However, the heel–sway and heel–yaw coupling can play an important role in potentially unsafe conditions, such as in a following sea. In these conditions, small fast vessels experience dynamic instabilities which threaten their ability to maintain a straight course. In this study, the coupling between the static heel and the sway force and yaw moment was investigated for a high-speed craft. The objective of this work is to understand the effect of heel on the manoeuvring in following waves, and to predict this effect by means of numerical tools for different combinations of wave characteristics and vessel speeds. A dedicated captive model test campaign was conducted to evaluate the manoeuvring loads in sway and yaw when the craft has a heel angle in following regular waves. The tests were performed in the towing tank of Delft University of Technology. The heel-induced loads depend strongly on the longitudinal position of the vessel in the wave, and they significantly differ from the heel-induced loads in calm water at the respective speed. The data carried out in the model tests were used to describe empirically the heel-induced loads for several combinations of ship speeds and wave characteristics. This empirical description was meant to correct a 3D potential flow boundary element method (BEM), with the objective of being able to predict these loads on a wide range of conditions. The corrected 3D BEM was used to simulate the behaviour of the high-speed craft in following regular waves. This analysis showed that the heel-induced loads have the effect of stabilizing the ship to the inception of dynamic instabilities in the following sea.","High-speed craft; Manoeuvrability-in-wave; Heel; Captive model tests; Boundary element method; broaching-to","en","journal article","","","","","","","","","","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:a8ddc99d-76bc-4bc6-b21b-6d703d67880c","http://resolver.tudelft.nl/uuid:a8ddc99d-76bc-4bc6-b21b-6d703d67880c","Comparing city image and brand identity in polycentric regions using network analysis","Wäckerlin, Niels (Student TU Delft); Hoppe, T. (TU Delft Organisation & Governance); Warnier, Martijn (TU Delft System Engineering); de Jong, W. Martin (Rotterdam School of Management)","","2019","In a globalising world, cities find themselves competing for visitors, residents, investors, and companies. They use place branding strategies to become more visible. However, conceptual and analytical confusion exists on the subjects of place image and brand identity, and current studies are limited to single cities, neglecting inter-city relationships at the regional level. In this paper, we examine how place image and brand identity of cities in polycentric regions can be compared with each other. Inspired by Zenker and Beckmann’s network analysis approach for studying place branding (J Place Manag Dev 6(1): 6–17, 2013), a method is introduced to compare image and identity networks for polycentric regions. We use this to complement traditional steps of concept mapping (i.e. elicitation, mapping, and aggregation), and apply it to analyse the illustrative case of four cities in the MRDH region within the Netherlands. Results of the comparative analysis between the image network and the identity network provide both visual and quantitative insights revealing structural differences. The network analysis research approach can be useful to both policy-makers and researchers in analysing city image and brand identity, and to develop place branding strategies accordingly, even at the regional level.","Brand identity; City branding; Network analysis; Place image; Polycentric regions","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2019-12-18","","","System Engineering","","",""
"uuid:c21d8633-397b-4ba8-95d4-bcbb4fa79f80","http://resolver.tudelft.nl/uuid:c21d8633-397b-4ba8-95d4-bcbb4fa79f80","High-definition imaging of carotid artery wall dynamics","Kruizinga, P. (Erasmus MC); Mastik, Frits (Erasmus MC); van den Oord, Stijn C.H. (Erasmus MC); Schinkel, Arend F.L. (Erasmus MC); Bosch, Johannes G. (Erasmus MC); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC; Interuniversity Cardiology Institute of the Netherlands); van Soest, G. (Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC; Chinese Academy of Sciences; Interuniversity Cardiology Institute of the Netherlands)","","2014","The carotid artery (CA) is central to cardiovascular research, because of the clinical relevance of CA plaques as culprits of stroke and the accessibility of the CA for cardiovascular screening. The viscoelastic state of this artery, essential for clinical evaluation, can be assessed by observing arterial deformation in response to the pressure changes throughout the cardiac cycle. Ultrasound imaging has proven to be an excellent tool to monitor these dynamic deformation processes. We describe how a new technique called high-frame-rate ultrasound imaging captures the tissue deformation dynamics throughout the cardiac cycle in unprecedented detail. Local tissue motion exhibits distinct features of sub-micrometer displacements on a sub-millisecond time scale. We present a high-definition motion analysis technique based on plane wave ultrasound imaging able to capture these features. We validated this method by screening a group of healthy volunteers and compared the results with those for two patients known to have atherosclerosis to illustrate the potential utility of this technique.","Carotid artery; High-frame-rate ultrasound; Plane wave imaging; Pulse wave velocity; Tissue Doppler","en","journal article","","","","","","","","2015-10-01","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:c947524b-312b-4311-8b24-f6cb98bb3139","http://resolver.tudelft.nl/uuid:c947524b-312b-4311-8b24-f6cb98bb3139","Accelerated 2D Real-Time Refraction-Corrected Transcranial Ultrasound Imaging","Mozaffarzadeh, M. (TU Delft ImPhys/Medical Imaging); Verschuur, D.J. (TU Delft ImPhys/Computational Imaging); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Renaud, G.G.J. (TU Delft ImPhys/Medical Imaging)","","2022","In a recent study, we proposed a technique to correct aberration caused by the skull and reconstruct a transcranial B-mode image with a refraction-corrected synthetic aperture imaging (SAI) scheme. Given a sound speed map, the arrival times were calculated using a fast marching technique (FMT), which solves the Eikonal equation and, therefore, is computationally expensive for real-time imaging. In this article, we introduce a two-point ray tracing method, based on Fermat's principle, for fast calculation of the travel times in the presence of a layered aberrator in front of the ultrasound probe. The ray tracing method along with the reconstruction technique is implemented on a graphical processing unite (GPU). The point spread function (PSF) in a wire phantom image reconstructed with the FMT and the GPU implementation was studied with numerical synthetic data and experiments with a bone-mimicking plate and a sagittally cut human skull. The numerical analysis showed that the error on travel times is less than 10% of the ultrasound temporal period at 2.5 MHz. As a result, the lateral resolution was not significantly degraded compared with images reconstructed with FMT-calculated travel times. The results using the synthetic, bone-mimicking plate, and skull dataset showed that the GPU implementation causes a lateral/axial localization error of 0.10/0.20, 0.15/0.13, and 0.26/0.32 mm compared with a reference measurement (no aberrator in front of the ultrasound probe), respectively. For an imaging depth of 70 mm, the proposed GPU implementation allows reconstructing 19 frames/s with full synthetic aperture (96 transmission events) and 32 frames/s with multiangle plane wave imaging schemes (with 11 steering angles) for a pixel size of $200~\mu \text{m}$. Finally, refraction-corrected power Doppler imaging is demonstrated with a string phantom and a bone-mimicking plate placed between the probe and the moving string. The proposed approach achieves a suitable frame rate for clinical scanning while maintaining the image quality.","","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2023-01-07","","","ImPhys/Medical Imaging","","",""
"uuid:9fa8c89a-c548-4eea-ba43-68a9cc4f1139","http://resolver.tudelft.nl/uuid:9fa8c89a-c548-4eea-ba43-68a9cc4f1139","Measurement of Pipe and Liquid Parameters Using the Beam Steering Capabilities of Array-Based Clamp-On Ultrasonic Flow Meters","Massaad Mouawad, J.M. (TU Delft ImPhys/Medical Imaging); van Neer, P.L.M.J. (TU Delft ImPhys/Medical Imaging; TNO); van Willigen, D.M. (TU Delft Electronic Instrumentation); Pertijs, M.A.P. (TU Delft Electronic Instrumentation); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC)","","2022","Clamp-on ultrasonic flow meters (UFMs) are installed on the outside of the pipe wall. Typically, they consist of two single-element transducers mounted on angled wedges, which are acoustically coupled to the pipe wall. Before flow metering, the transducers are placed at the correct axial position by manually moving one transducer along the pipe wall until the maximum amplitude of the relevant acoustic pulse is obtained. This process is time-consuming and operator-dependent. Next to this, at least five parameters of the pipe and the liquid need to be provided manually to compute the flow speed. In this work, a method is proposed to obtain the five parameters of the pipe and the liquid required to compute the flow speed. The method consists of obtaining the optimal angles for different wave travel paths by varying the steering angle of the emitted acoustic beam systematically. Based on these optimal angles, a system of equations is built and solved to extract the desired parameters. The proposed method was tested experimentally with a custom-made clamp-on UFM consisting of two linear arrays placed on a water-filled stainless steel pipe. The obtained parameters of the pipe and the liquid correspond very well with the expected (nominal) values. Furthermore, the performed experiment also demonstrates that a clamp-on UFM based on transducer arrays can achieve self-alignment without the need to manually move the transducers","beam alignment; clamp-on ultrasonic flow meter; self-calibration; transducer arrays","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:9c68150c-3c00-4d3f-ab1e-6e507ab10226","http://resolver.tudelft.nl/uuid:9c68150c-3c00-4d3f-ab1e-6e507ab10226","Mechanical dissipation by substrate–mode coupling in SiN resonators","de Jong, M.H.J. (TU Delft QN/Groeblacher Lab; TU Delft Dynamics of Micro and Nano Systems); ten Wolde, M.A. (TU Delft Mechatronic Systems Design); Cupertino, A. (TU Delft Dynamics of Micro and Nano Systems); Groeblacher, S. (TU Delft QN/Groeblacher Lab); Steeneken, P.G. (TU Delft Dynamics of Micro and Nano Systems; TU Delft QN/Steeneken Lab); Norte, R.A. (TU Delft QN/Groeblacher Lab; TU Delft Dynamics of Micro and Nano Systems)","","2022","State-of-the-art nanomechanical resonators are heralded as a central component for next-generation clocks, filters, resonant sensors, and quantum technologies. To practically build these technologies will require monolithic integration of microchips, resonators, and readout systems. While it is widely seen that mounting microchip substrates into a system can greatly impact the performance of high-Q resonators, a systematic study has remained elusive, owing to the variety of physical processes and factors that influence the dissipation. Here, we analytically analyze a mechanism by which substrates couple to resonators manufactured on them and experimentally demonstrate that this coupling can increase the mechanical dissipation of nanomechanical resonators when resonance frequencies of resonator and substrate coincide. More generally, we then show that a similar coupling mechanism can exist between two adjacent resonators. Since the substrate–mode coupling mechanism strongly depends on both the resonator position on the substrate and the mounting of the substrate, this work provides key design guidelines for high-precision nanomechanical technologies.","","en","journal article","","","","","","","","","","","QN/Groeblacher Lab","","",""
"uuid:fe622d93-9aed-4731-9240-50196c3781e3","http://resolver.tudelft.nl/uuid:fe622d93-9aed-4731-9240-50196c3781e3","Comparison of Phase-Screen and Geometry-Based Phase Aberration Correction Techniques for Real-Time Transcranial Ultrasound Imaging","Mozaffarzadeh, M. (TU Delft ImPhys/Medical Imaging); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Renaud, G.G.J. (TU Delft ImPhys/Medical Imaging)","","2022","While transcranial ultrasound imaging is a promising diagnostic modality, it is still hindered due to phase aberration and multiple scattering caused by the skull. In this paper, we compare near-field phase-screen modeling (PS) to a geometry-based phase aberration correction technique (GB) when an ultrafast imaging sequence (five plane waves tilted from −15 to +15 degrees in the cutaneous tissue layer) is used for data acquisition. With simulation data, the aberration profile (AP) of two aberrator models (flat and realistic temporal bone) was estimated in five isoplanatic patches, while the wave-speed of the brain tissue surrounding the point targets was either modeled homogeneously (ideal) or slightly heterogeneously to generate speckle (for mimicking a more realistic brain tissue). For the experiment, a phased array P4-1 transducer was used to image a wire phantom; a 4.2-mm-thick bone-mimicking plate was placed in front of the probe. The AP of the plate was estimated in three isoplanatic patches. The numerical results indicate that, while all the scatterers are detectable in the image reconstructed by the GB method, many scatterers are not detected with the PS method when the dataset used for AP estimation is generated with a realistic bone model and heterogeneous brain tissue. The experimental results show that the GB method increases the signal-to-clutter ratio (SCR) by 7.5 dB and 6.5 dB compared to the PS and conventional reconstruction methods, respectively. The GB method reduces the axial/lateral localization error by 1.97/0.66 mm and 2.08/0.7 mm compared to the PS method and conventional reconstruction, respectively. The lateral spatial resolution (full-width-half-maximum) is also improved by 0.1 mm and 1.06 mm compared to the PS method and conventional reconstruction, respectively. Our comparison study suggests that GB aberration correction outperforms the PS method when an ultrafast multi-angle plane wave sequence is used for transcranial imaging with a single transducer.","transcranial ultrasound imaging; phase aberration correction; near-field phase-screen modeling; adaptive beamforming; temporal bone","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:9c316b18-8c8d-4959-a541-87980bc5fcc4","http://resolver.tudelft.nl/uuid:9c316b18-8c8d-4959-a541-87980bc5fcc4","Photovoltaic Potential of the Dutch Inland Shipping Fleet: An Experimentally Validated Method to Simulate the Power Series from Vessel-Integrated Photovoltaics","de Jong, Dora (Student TU Delft); Ziar, H. (TU Delft Photovoltaic Materials and Devices)","","2022","The surface of the vessels, as moving tiny islands, can be utilized to implement vehicle-integrated photovoltaics (VIPV). Herein, a methodology is reported to calculate the power generated by a fleet of urban vessels as a function of time. Then, the result is shown for the largest European shipping fleet, using sailing data of 2746 Dutch general cargo vessels. Results show that the studied fleet can produce ≈ 226 GWh of energy per year, which corresponds to ≈ 6.5% of the whole fleet's energy demand. Next, this research validates the model with three week experimental data gathered by a test vessel sailing through the Netherlands. The validation phase reveals that the model can predict within a 4% error range. Finally, as an interesting finding, it is experimentally shown that the energy production profile of a fleet of urban vessels follows a Weibull distribution, quantified by scale (λ) and shape (k) parameters: λ = 880 Wh Wp−1 and k = 27 for the Dutch fleet. A sensitivity analysis shows that the parameters of the Weibull distribution are a function of urban fabric roughness and the climate. Such probability distribution can be extended to other urban fleets, such as solar cars, and help estimate the financial feasibility of integrating PV into vehicles.","ships; solar photovoltaic potential; urban area; vehicle-integrated photovoltaics (VIPV); waterways","en","journal article","","","","","","","","","","","Photovoltaic Materials and Devices","","",""
"uuid:f8a52ff6-aa6f-48b3-8d46-f61ab3db3838","http://resolver.tudelft.nl/uuid:f8a52ff6-aa6f-48b3-8d46-f61ab3db3838","Sparse 2-D PZT-on-PCB Arrays With Density Tapering","Wei, Luxi (Erasmus MC); Boni, Enrico (University of Florence); Ramalli, Alessandro (University of Florence); Fool, F. (TU Delft ImPhys/Medical Imaging); Noothout, E.C. (TU Delft ImPhys/Medical Imaging); van der Steen, A.F.W. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Tortoli, Piero (University of Florence); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Vos, H.J. (TU Delft ImPhys/Medical Imaging; Erasmus MC)","","2022","Two-dimensional (2-D) arrays offer volumetric imaging capabilities without the need for probe translation or rotation. A sparse array with elements seeded in a tapering spiral pattern enables one-to-one connection to an ultrasound machine, thus allowing flexible transmission and reception strategies. To test the concept of sparse spiral array imaging, we have designed, realized, and characterized two prototype probes designed at 2.5-MHz low-frequency (LF) and 5-MHz high-frequency (HF) center frequencies. Both probes share the same electronic design, based on piezoelectric ceramics and rapid prototyping with printed circuit board substrates to wire the elements to external connectors. Different center frequencies were achieved by adjusting the piezoelectric layer thickness. The LF and HF prototype probes had 88% and 95% of working elements, producing peak pressures of 21 and 96 kPa/V when focused at 5 and 3 cm, respectively. The one-way -3-dB bandwidths were 26% and 32%. These results, together with experimental tests on tissue-mimicking phantoms, show that the probes are viable for volumetric imaging.","matrix array; PZT-on-printed circuit board (PCB); sparse array; Three-dimensional (3-D) imaging; transducer; two-dimensional (2-D) array; ultrasound (US); volume imaging","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2023-07-01","","","ImPhys/Medical Imaging","","",""
"uuid:2e7d4088-5228-474e-95b9-608821caac74","http://resolver.tudelft.nl/uuid:2e7d4088-5228-474e-95b9-608821caac74","Numerical Evaluation of Biochar Production Performance of Downdraft Gasifier by Thermodynamic Model","Shin, Donghoon (Kookmin University); Francis, Akhil (St. Joseph’s College of Engineering and Technology Palai); Aravind, P.V. (TU Delft Energy Technology; Rijksuniversiteit Groningen); Woudstra, T. (TU Delft Process and Energy); de Jong, W. (TU Delft Large Scale Energy Storage); Roekaerts, D.J.E.M. (TU Delft Fluid Mechanics)","","2022","A theoretical evaluation of the biochar production process using a biomass gasifier has been carried out herein. Being distinguished from the previous research trend examining the use of a biomass gasifier, which has been focused on energy efficiency, the present study tries to figure out the effect of biochar production rate on the overall process performance because biochar itself has now been given a spotlight as the main product. Biochar can be utilized for agricultural and industrial purposes, along with the benefit of climate change mitigation. A thermodynamic model based on chemical equilibrium analysis is utilized to demonstrate the effect of biochar production rate on the producer gas characteristics such as gas composition, LHV (lower heating value) and cold gas efficiency. Three gasifier models using chemical equilibrium model are reconstructed to simulate biochar-producing gasifiers, and seven kinds of biomass are considered as feed material. Depending on the assumptions applied to the models as well as the biomass types, the results of the simulation show a large variance, whereas the biochar yield rate increases. Through regression analysis with a generalized reduced gradient optimization method, simplified equations to estimate the cold gas efficiency (CGE) and LHV of producer gas of the biochar production process were derived as having six parameters of biomass LHV, fractions of ash, carbon and water, reduction zone temperature, and biochar yield rate. The correlation factors between the thermodynamic model and the regression model are 96.54% and 98.73% for the LHV of producer gas and CGE, respectively. These equations can supply the pre-estimation of the theoretical maximum performance of a planning biochar plant.","biomass; biochar; downdraft gasifier; thermodynamic model; correlation equation","en","journal article","","","","","","","","","","Process and Energy","Energy Technology","","",""
"uuid:b1ed66cf-4de5-4d90-b964-29ae7c362b3e","http://resolver.tudelft.nl/uuid:b1ed66cf-4de5-4d90-b964-29ae7c362b3e","A modelling based study on the integration of 10 MWth indirect torrefied biomass gasification, methanol and power production","Del Grosso, M. (TU Delft Large Scale Energy Storage); Sridharan, Balaji (Rijksuniversiteit Groningen); Tsekos, C. (TU Delft Large Scale Energy Storage); Klein, S.A. (TU Delft Energy Technology); de Jong, W. (TU Delft Large Scale Energy Storage; Rijksuniversiteit Groningen)","","2020","This work is focused on the process system modelling of an indirectly heated gasifier (10 MWth) using torrefied wood as feedstock and its integration with methanol and power production using Aspen Plus®. The modelling of the gasification process along with the obtained reaction kinetics were validated with experimental data found in literature. Different processing steps such as gasification, gas cleaning and upgrading, methanol synthesis and energy conversion, were modelled and their performance was optimized through a series of sensitivity studies. The results obtained were then used to investigate the effect of different technologies and the variation of operational parameters on the overall process performance. Three cases were examined: “syngas production” (case 1), “methanol production” (case 2), and “power production” (IGCC) (case 3). Case 1 and case 2 were simulated using sand and dolomite as bed materials respectively, in order to study the incorporation of Absorption Enhanced Reforming (AER) on the syngas and methanol production efficiency. For case 3 the simulation was performed for two different configurations: a conventional Integrated Gasification Combined Cycle (IGCC) and an innovative Inverted Brayton Cycle (IBC) turbine system. Dolomite was used as the bed material for both configurations. For case 1, an increase of 5% in hydrogen yield in the product gas when AER is applied was observed. For case 2, higer values of Cold Gas Efficiency and Net Efficiency (34% and 60% instead of 33% and 55%, respectively) and a slightly lower value of Carbon Conversion (96% instead of 100%) were obtained when AER was employed. Gasification temperature was lowered by 110 °C in this scenario. For case 3, a lower value of Net Efficiency was obtained when IBC was considered (43% instead of 47%), while a value of 60% was obtained for methanol production with AE. Moreover, the results of case 3, showed that the latent heat in the hot syngas is best utilised when IBC is considered. The developed model accurately predicted the composition of the produced gas and the operational conditions of all the identified blocks within the methanol synthesis and power production processes. This way the use of this model as a generic tool to compare the utilization of different technologies on the performance of the overall process was validated.","Absorption enhanced reforming; Allothermal gasification; Biomethanol; Integrated gasification combined cycle systems; Process system modelling; Tar removal","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:49f6b7b1-a1c7-4473-bd02-674a153b4da5","http://resolver.tudelft.nl/uuid:49f6b7b1-a1c7-4473-bd02-674a153b4da5","The Effect of Environmental Conditions on the Degradation Behavior of Biomass Pellets","Gilvari, H. (TU Delft Transport Engineering and Logistics); Cutz, L. (TU Delft Large Scale Energy Storage); Tiringer, U. (TU Delft (OLD) MSE-6); Mol, J.M.C. (TU Delft (OLD) MSE-6); de Jong, W. (TU Delft Large Scale Energy Storage); Schott, D.L. (TU Delft Transport Engineering and Logistics)","","2020","Biomass pellets provide a pivotal opportunity in promising energy transition scenarios as a renewable source of energy. A large share of the current utilization of pellets is facilitated by intensive global trade operations. Considering the long distance between the production site and the end-user locations, pellets may face fluctuating storage conditions, resulting in their physical and chemical degradation. We tested the effect of different storage conditions, from freezing temperatures (−19 °C) to high temperature (40 °C) and humidity conditions (85% relative humidity), on the physicochemical properties of untreated and torrefied biomass pellets. Moreover, the effect of sudden changes in the storage conditions on pellet properties was studied by moving the pellets from the freezing to the high temperature and relative humidity conditions and vice versa. The results show that, although storage at one controlled temperature and RH may degrade the pellets, a change in the temperature and relative humidity results in higher degradation in terms of higher moisture uptake and lower mechanical strength.","biomass pellets; storage effects; mechanical durability; heating value; equilibrium moisture content","en","journal article","","","","","","","","","","","Transport Engineering and Logistics","","",""
"uuid:7fa9f695-987f-4b93-a7f5-e32fad794704","http://resolver.tudelft.nl/uuid:7fa9f695-987f-4b93-a7f5-e32fad794704","Classifying Pathways for Smart City Development: Comparing Design, Governance and Implementation in Amsterdam, Barcelona, Dubai, and Abu Dhabi","Noori, Negar (Erasmus Universiteit Rotterdam); Hoppe, T. (TU Delft Organisation & Governance); de Jong, Martin (Rotterdam School of Management; Fudan University)","","2020","The emergence of the Internet of Things (IoT) as the new paradigm of Information and Communication Technology (ICT) and rapid changes in technology and urban needs urge cities around the world towards formulating smart city policies. Nevertheless, policy makers, city planners, and practitioners appear to have quite different expectations from what smart cities can offer them. This has led to the emergence of different types of smart cities and pathways of development. This paper aims to answer the research question: When comparing a selection of smart city projects, can we classify pathways for their implementation? We do this by using a cross-case research design of four cities to explore commonalities and differences in development patterns. An input-output (IO) model of smart city development is used to retrieve which design variables are at play and lead to which output. The four cases pertain to the following smart city projects: Smart Dubai, Masdar City, Barcelona Smart City, and Amsterdam Smart City. Our analysis shows that Amsterdam is based on a business-driven approach that puts innovation at its core; for Masdar, technological optimism is the main essence of the pathway; social inclusion is the focus of Barcelona Smart City; and visionary ambitious leadership is the main driver for Smart Dubai. Based on these insights, a classification for smart city development pathways is established. The results of the present study are useful to academic researchers, smart city practitioners, and policy makers.","Amsterdam Smart City; Barcelona Smart City; Comparative analysis; Design variables; Digitization; Input-output model; Masdar City; Smart city; Smart Dubai; Smart governance","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:3f0041c3-eadd-43fd-9f52-fe0ef9be72c3","http://resolver.tudelft.nl/uuid:3f0041c3-eadd-43fd-9f52-fe0ef9be72c3","Towards a calibration-free ultrasonic clamp-on flow meter: Pipe geometry measurements using matrix arrays: Pipe geometry measurements using matrix arrays","Massaad Mouawad, J.M. (TU Delft ImPhys/Medical Imaging); van Neer, P.L.M.J. (TNO); van Willigen, D.M. (TU Delft Electronic Instrumentation); Pertijs, M.A.P. (TU Delft Electronic Instrumentation); de Jong, N. (TU Delft ImPhys/Medical Imaging); Verweij, M.D. (TU Delft ImPhys/Medical Imaging)","","2020","Current ultrasonic clamp-on flow meters are manually calibrated. This process is based on manual placement of two single-element transducers along a pipe wall. Due to the usually unknown pipe properties and inhomogeneities in the pipe geometry, the axial distance of the transducers needs to be manually calibrated to align the location of the emitted beam on the receiver. In this work it is presented an automatic calibration procedure, based on matrix transducer arrays, to provide calibration information that would normally be entered into the instrument manually prior to ultrasonic clamp-on flow measurements. The calibration consists of two steps: First, along the axial direction of the pipe, Lamb waves are excited and recorded. Then, the measured time signals are combined with the Rayleigh-Lamb dispersion equation to extract pipe wall thickness and bulk wave sound speeds. Second, along the circumferential direction of the pipe, a specific Lamb wave mode is excited and recorded, from which the pipe diameter is estimated. The potential of both calibration procedures is shown, and the necessity of a matrix transducer array (i.e. small elements) is highlighted","","en","journal article","","","","","","","","2021-05-25","","","ImPhys/Medical Imaging","","",""
"uuid:f41e3fb8-5817-4720-82b5-79475d3d1908","http://resolver.tudelft.nl/uuid:f41e3fb8-5817-4720-82b5-79475d3d1908","Fundamental modeling of wave propagation in temporally relaxing media with applications to cardiac shear wave elastography","Sabbadini, A. (TU Delft ImPhys/Medical Imaging); Keijzer, L.B.H. (Erasmus MC); Vos, H.J. (Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging); Verweij, M.D. (TU Delft ImPhys/Medical Imaging)","","2020","Shear wave elastography (SWE) might allow non-invasive assessment of cardiac stiffness by relating shear wave propagation speed to material properties. However, after aortic valve closure, when natural shear waves occur in the septal wall, the stiffness of the muscle decreases significantly, and the effects of such temporal variation of medium properties on shear wave propagation have not been investigated yet. The goal of this work is to fundamentally investigate these effects. To this aim, qualitative results were first obtained experimentally using a mechanical setup, and were then combined with quantitative results from finite difference simulations. The results show that the amplitude and period of the waves increase during propagation, proportional to the relaxation of the medium, and that reflected waves can originate from the temporal stiffness variation. These general results, applied to literature data on cardiac stiffness throughout the heart cycle, predict as a major effect a period increase of 20% in waves propagating during a healthy diastolic phase, whereas only a 10% increase would result from the impaired relaxation of an infarcted heart. Therefore, cardiac relaxation can affect the propagation of waves used for SWE measurements and might even provide direct information on the correct relaxation of a heart.","","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:fd562957-b5ce-4820-b9f3-dbe76001c8ef","http://resolver.tudelft.nl/uuid:fd562957-b5ce-4820-b9f3-dbe76001c8ef","Lamb Waves and Adaptive Beamforming for Aberration Correction in Medical Ultrasound Imaging","Mozaffarzadeh, M. (TU Delft ImPhys/Medical Imaging); Minonzio, C.G. (TU Delft ImPhys/Medical Imaging); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Hemm, Simone (University of Applied Sciences and Arts Northwestern Switzerland); Daeichin, V. (TU Delft ImPhys/Medical Imaging)","","2020","Phase aberration in transcranial ultrasound imaging (TUI) caused by the human skull leads to an inaccurate image reconstruction. In this article, we present a novel method for estimating the speed of sound and an adaptive beamforming technique for phase aberration correction in a flat polyvinylchloride (PVC) slab as a model for the human skull. First, the speed of sound of the PVC slab is found by extracting the overlapping quasi-longitudinal wave velocities of symmetrical Lamb waves in the frequency-wavenumber domain. Then, the thickness of the plate is determined by the echoes from its front and back side. Next, an adaptive beamforming method is developed, utilizing the measured sound speed map of the imaging medium. Finally, to minimize reverberation artifacts caused by strong scatterers (i.e., needles), a dual probe setup is proposed. In this setup, we image the medium from two opposite directions, and the final image can be the minimum intensity projection of the inherently co-registered images of the opposed probes. Our results confirm that the Lamb wave method estimates the longitudinal speed of the slab with an error of 3.5% and is independent of its shear wave speed. Benefiting from the acquired sound speed map, our adaptive beamformer reduces (in real time) a mislocation error of 3.1, caused by an 8 mm slab, to 0.1 mm. Finally, the dual probe configuration shows 7 dB improvement in removing reverberation artifacts of the needle, at the cost of only 2.4-dB contrast loss. The proposed image formation method can be used, e.g., to monitor deep brain stimulation procedures and localization of the electrode(s) deep inside the brain from two temporal bones on the sides of the human skull.","Transcranial ultrasound imaging; Lamb waves; adaptive beamforming; sound speed map; deep brain stimulation","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2021-01-06","","","ImPhys/Medical Imaging","","",""
"uuid:c58ca52c-3c3b-4300-9b4f-40890d292ba3","http://resolver.tudelft.nl/uuid:c58ca52c-3c3b-4300-9b4f-40890d292ba3","The Effect of Biomass Pellet Length, Test Conditions and Torrefaction on Mechanical Durability Characteristics According to ISO Standard 17831-1","Gilvari, H. (TU Delft Transport Engineering and Logistics); de Jong, W. (TU Delft Large Scale Energy Storage); Schott, D.L. (TU Delft Transport Engineering and Logistics)","","2020","With the recent increase in biomass pellet consumption, the mechanical degradation of pellets during transport and handling has become more important. ISO standard 17831-1 is an accepted global standard that is commonly used amongst researchers and industries to determine the mechanical durability of pellets. However, the measured mechanical durability sometimes fails to match the certificate accompanying the shipment. In such cases, pellet length specifications are suspected to play a role. This paper studies the effect of pellet length on mechanical durability for various types of commercially produced biomass pellets. In addition, the effect of test conditions and torrefaction on the mechanical durability of biomass pellets has been investigated. To study the effect of pellet length, pellets were classified into three groups: shorter than 15 mm, 15 to 30 mm, and longer than 30 mm, and their length distributions were measured using an in-house image processing tool. Then, the mechanical durability of pellets was measured using ISO standard 17831-1. The mechanical durability results were compared to random-sized pellet samples. To study the effect of test conditions, the mechanical durability test was operated at different time intervals to elucidate the effect of tumbling at different conditions. The results show that the mechanical durability depends highly on the length distribution of the pellets, with a difference between categories of up to 13%. It was also observed that the mechanical durability remains relatively constant after a specific time interval. Based on the results, we highly recommend modifying the current ISO standard to account for the pellet length distribution (PLD)","biomass pellet; mechanical durability; ISO standard 17831-1; pellet length distribution; image processing","en","journal article","","","","","","","","","","","Transport Engineering and Logistics","","",""
"uuid:03ec1798-1285-42a4-a97b-f7f15f951200","http://resolver.tudelft.nl/uuid:03ec1798-1285-42a4-a97b-f7f15f951200","Economic city branding and stakeholder involvement in China: Attempt of a medium-sized city to trigger industrial transformation","Ma, W. (TU Delft Organisation & Governance; Erasmus Universiteit Rotterdam); de Jong, Martin (Erasmus Universiteit Rotterdam; Fudan University); de Bruijne, M.L.C. (TU Delft Organisation & Governance); Schraven, D.F.J. (TU Delft Integral Design & Management)","","2020","Among known studies of city branding by Chinese megacities to realise urban transformation, there is no explorative study of how smaller Chinese cities engage in city branding and attempt to trigger industrial transformation. In response, this article presents an in-depth case study of city branding processes in a medium-sized Chinese city. Roles, resources and interactions among the city's stakeholders are analysed during the brand creation and implementation stages in two different economic city branding projects. The stakeholder involvement mechanisms we identify confirm that city branding creation in China primarily follows political rather than business channels. Chinese local public authorities and more specifically key politicians, departments, and public enterprises are core stakeholders in branding creation. However, this leads to challenges in the branding implementation, since key public sector players tend to withdraw themselves when implementation begins, leaving previously uninvolved private (and public) players to implement the brands. The unsuccessful transformation contrasts with those observed in Chinese megacities, where involvement of powerful corporations and support from higher levels of government are both much higher. It appears that the imperative of broad stakeholder involvement to make city branding successful as we know it for Western cities may also apply in medium-sized Chinese cities.","Brand creation and implementation; China; Economic city branding; Industrial transformation; Medium-sized city; Stakeholder involvement","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:3c462057-7d71-4f17-8086-2dfd66990a48","http://resolver.tudelft.nl/uuid:3c462057-7d71-4f17-8086-2dfd66990a48","New Town Development and Sustainable Transition under Urban Entrepreneurialism in China","Song, Y. (TU Delft Organisation & Governance); Stead, D. (TU Delft Spatial Planning and Strategy); de Jong, Martin (Rotterdam School of Management; Fudan University; Erasmus Universiteit Rotterdam)","","2020","New towns are a major form of urban growth in China. In recent years, increasing numbers of large new town projects have been planned and built in and around existing cities. These new town projects have frequently been employed by city governments as central elements of pro-growth strategies, based on ideas of urban entrepreneurialism, which seek to promote economic growth, project a dynamic city image, and increase urban competitiveness. This article studies how the pro-growth, urban entrepreneurial approach affects the planning and development of Chinese megacities. A conceptual framework focusing on land-leasing revenue and new town development strategies is employed to explore the linkages between urban growth mechanisms and urban outcomes. Empirical material from four cities in the Pearl River Delta—Guangzhou, Shenzhen, Foshan, and Zhuhai—is presented. The analysis indicates that new town developments in these cities have different levels of dependency on spatial expansion and land revenue, and emphasize different issues of sustainable development in their plans. Cities with a lower dependency on physical and economic growth are be more likely to emphasize the quality of the built environment and address issues of sustainable urban development more closely when planning and implementing new town projects.","Land-driven economy; New town development; Pearl river delta; Urban entrepreneurialism","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:6cca46e6-d492-4b41-b5ef-4649714499c9","http://resolver.tudelft.nl/uuid:6cca46e6-d492-4b41-b5ef-4649714499c9","Cybernetic Data Augmentation for Neural Network Classification of Control Skills","de Jong, M.A. (TU Delft Electrical Engineering, Mathematics and Computer Science); Pool, D.M. (TU Delft Control & Simulation); Mulder, Max (TU Delft Control & Simulation)","","2022","Mathematical human controller (HC) models are widely used in tuning manual control systems and for understanding human performance. Typically, quasi-linear HC models are used, which can accurately capture the linear portion of HCs' behavior, averaged over a long measurement window. This paper presents a deep learning HC skill-level evaluation method that works on short windows of raw HC time signals, and accounts for both the linear and non-linear portions of HC behavior. This deep learning approach is applied to data from a previous skill training experiment performed in the SIMONA Research Simulator at TU Delft. Additional human control data is generated using cybernetic HC model simulations. The results indicate that the deep learning evaluation method is successful in predicting HC skill level with 85-90% validation accuracy, but that training the classifier solely on simulated HC data reduces this accuracy by 15-25%. Inspection of the results especially shows a strong sensitivity of the classifier to the presence of remnant in the simulated training data. In conclusion, these results reveal that current quasi-linear HC model simulations, and in particular the remnant portion, do not adequately capture real time-domain HC behavior to allow effective training-data augmentation.","classification; control skills; Cybernetics; manual control; neural networks","en","journal article","","","","","","","","","Electrical Engineering, Mathematics and Computer Science","","Control & Simulation","","",""
"uuid:e23261e2-64ee-4e8c-9fc6-88701d0fe85c","http://resolver.tudelft.nl/uuid:e23261e2-64ee-4e8c-9fc6-88701d0fe85c","Determining Air Traffic Controller Proficiency: Identifying Objective Measures Using Clustering","de Jong, T. P. (Student TU Delft); Borst, C. (TU Delft Control & Simulation)","","2022","Air traffic control (ATC) is a complex and demanding job reserved for highly-trained professionals. Training ATC candidates is challenging as trainees are subjectively assessed by instructors who are biased by their own ways of working. As an effort to determine control expertise objectively, this study employed clustering techniques on an existing data set in which course and professional controllers participated in a medium-fidelity simulation experiment. Results identified a set of eight measures that formed two distinct and stable expertise clusters. A subsequent sensitivity analysis was able to reveal how far (or close) each course participant was positioned from the expert cluster and on which measures those participants deviated from the experts. At this stage, however, it is difficult to translate these results into specific advice on how to improve underdeveloped skills. Despite the small sample size and limited generalizability of the results in this exploratory study, the method appears to be a promising demonstration in determining objective factors that describe ATC expertise, warranting further research.","cooperation; Decision making and cognitive processes; degree of automation; Human centred automation; Shared control","en","journal article","","","","","","","","","","","Control & Simulation","","",""
"uuid:2fc6d02b-fe4b-44e3-b8d2-6e30dd92f457","http://resolver.tudelft.nl/uuid:2fc6d02b-fe4b-44e3-b8d2-6e30dd92f457","ATP binding by an F1Fo ATP synthase ε subunit is pH dependent, suggesting a diversity of ε subunit functional regulation in bacteria","Krah, Alexander (Korea Institute for Advanced Study; Agency for Science, Technology and Research); Vogelaar, Timothy (Student TU Delft); de Jong, S.I. (TU Delft BT/Environmental Biotechnology); Claridge, Jolyon K. (Massey University); Bond, Peter J. (Agency for Science, Technology and Research; National University of Singapore); McMillan, D.G.G. (TU Delft BT/Biocatalysis; Massey University)","","2023","It is a conjecture that the ε subunit regulates ATP hydrolytic function of the F1Fo ATP synthase in bacteria. This has been proposed by the ε subunit taking an extended conformation, with a terminal helix probing into the central architecture of the hexameric catalytic domain, preventing ATP hydrolysis. The ε subunit takes a contracted conformation when bound to ATP, thus would not interfere with catalysis. A recent crystallographic study has disputed this; the Caldalkalibacillus thermarum TA2.A1 F1Fo ATP synthase cannot natively hydrolyse ATP, yet studies have demonstrated that the loss of the ε subunit terminal helix results in an ATP synthase capable of ATP hydrolysis, supporting ε subunit function. Analysis of sequence and crystallographic data of the C. thermarum F1Fo ATP synthase revealed two unique histidine residues. Molecular dynamics simulations suggested that the protonation state of these residues may influence ATP binding site stability. Yet these residues lie outside
the ATP/Mg2+ binding site of the ε subunit. We then probed the effect of pH on the ATP binding affinity of the ε subunit from the C. thermarum F1Fo ATP synthase at various physiologically relevant pH values. We show that binding affinity changes 5.9 fold between pH 7.0, where binding is weakest, to pH 8.5 where it is strongest. Since the C. thermarum cytoplasm is pH 8.0 when it grows optimally, this correlates to the ε subunit being down due to ATP/Mg2+ affinity, and not being involved in blocking ATP hydrolysis. Here, we have experimentally correlated that the pH of the bacterial cytoplasm is of critical importance for ε subunit ATP affinity regulated by second shell residues thus the function of the ε subunit changes with growth conditions.","F1Fo ATP synthase; regulation-physiologica; alkaliphile bacteria; aerobe; polyextreme environments","en","journal article","","","","","","","","","","","BT/Environmental Biotechnology","","",""
"uuid:71845bfe-2100-4fc4-b767-3adffac41acb","http://resolver.tudelft.nl/uuid:71845bfe-2100-4fc4-b767-3adffac41acb","Ultrasonic Characterization of Ibidi μ-Slide I Luer Channel Slides for Studies With Ultrasound Contrast Agents","Zangabad, Reza Pakdaman (Erasmus MC); Li, H. (Erasmus MC); Kouijzer, Joop J.P. (Erasmus MC); Langeveld, Simone A.G. (Erasmus MC); Beekers, Ines (Erasmus MC); Verweij, M.A. (TU Delft Technology, Policy and Management); de Jong, N. (TU Delft ImPhys/De Jong group; Erasmus MC); Kooiman, Klazina (Erasmus MC)","","2023","Understanding and controlling the ultrasound contrast agent (UCA)'s response to an applied ultrasound pressure field are crucial when investigating ultrasound imaging sequences and therapeutic applications. The magnitude and frequency of the applied ultrasonic pressure waves affect the oscillatory response of the UCA. Therefore, it is important to have an ultrasound compatible and optically transparent chamber in which the acoustic response of the UCA can be studied. The aim of our study was to determine the in situ ultrasound pressure amplitude in the ibidi μ -slide I Luer channel, an optically transparent chamber suitable for cell culture, including culture under flow, for all microchannel heights (200, 400, 600, and 800 μm). First, the in situ pressure field in the 800- μm high channel was experimentally characterized using Brandaris 128 ultrahigh-speed camera recordings of microbubbles (MBs) and a subsequent iterative processing method, upon insonification at 2 MHz, 45° incident angle, and 50-kPa peak negative pressure (PNP). Control studies in another cell culture chamber, the CLINIcell, were compared with the obtained results. The pressure amplitude was -3.7 dB with respect to the pressure field without the ibidi μ -slide. Second, using finite-element analysis, we determined the in situ pressure amplitude in the ibidi with the 800- μm channel (33.1 kPa), which was comparable to the experimental value (34 kPa). The simulations were extended to the other ibidi channel heights (200, 400, and 600 μm) with either 35° or 45° incident angle, and at 1 and 2 MHz. The predicted in situ ultrasound pressure fields were between -8.7 and -1.1 dB of the incident pressure field depending on the listed configurations of ibidi slides with different channel heights, applied ultrasound frequencies, and incident angles. In conclusion, the determined ultrasound in situ pressures demonstrate the acoustic compatibility of the ibidi μ -slide I Luer for different channel heights, thereby showing its potential for studying the acoustic behavior of UCAs for imaging and therapy.","Acoustics; Biomedical optical imaging; drug delivery; Imaging; Microbubble; Optical variables control; Oscillators; Recording; ultra-high-speed imaging; Ultrasonic characterization; Ultrasonic imaging; ultrasound contrast agents (UCAs)","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2023-08-27","Technology, Policy and Management","","ImPhys/De Jong group","","",""
"uuid:95d685dd-719f-4649-b61d-1af5a6716697","http://resolver.tudelft.nl/uuid:95d685dd-719f-4649-b61d-1af5a6716697","Estimation of lignocellulosic biomass pyrolysis product yields using artificial neural networks","Tsekos, C. (TU Delft Large Scale Energy Storage); Tandurella, S. (Student TU Delft); de Jong, W. (TU Delft Large Scale Energy Storage; Rijksuniversiteit Groningen)","","2021","As the push towards more sustainable ways to produce energy and chemicals intensifies, efforts are needed to refine and optimize the systems that can give an answer to these needs. In the present work, the use of neural networks as modelling tools for lignocellulosic biomass pyrolysis main products yields estimation was evaluated. In order to achieve this, the most relevant compositional and reaction parameters for lignocellulosic biomass pyrolysis were reviewed and their effect over the main products yields was assessed. Based on relevant literature data, a database was set up, containing parameters and experimental results from 32 published studies for a total of 482 samples, including both fast and slow pyrolysis experiments performed on a heterogeneous collection of lignocellulosic biomasses. The parameters that in the database configured as best predictors for the solid, liquid and gaseous products were determined through preliminary tests and were then used to build reduced models, one for each of the main products, which use five parameters instead of the full set for the estimation of yields. The procedures included hyperparameter optimizations steps. The performances of these reduced models were compared to those of the ones obtained using the full set of parameters as inputs by using the root mean squared error (RMSE) as metric. For both the char and gas products, the best results were consistently achieved by the reduced versions of the network (RMSE 5.1 wt% ar and 5.6 wt% ar respectively), while for the liquid product the best result was given by the full network (RMSE 6.9 wt% ar) indicating substantial value in proper selection of the input features. In general, the char models were the best performing ones. Additional models for the liquid and gas product featuring char as additional input to the system were also devised and obtained better performance (RMSE 5.5 wt% ar and 4.9 wt% ar respectively) compared to the original ones. Models based on single studies were also included in order to showcase both the capabilities of the tool and the challenges that arise when trying to build a generalizable model of this kind. Overall, artificial neural networks were shown to be an interesting tool for the construction of setup-unspecific biomass pyrolysis product yield models. The obstacles standing currently in the way of a more accurate modelling of the system were highlighted, along with certain literature discrepancies, which hinder reliable quantitative comparison of experimental conditions and results among separate studies.","Artificial neural networks; Biomass modelling; Pyrolysis","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:afc2d39f-fd74-4f66-bd3c-0b514d7791e0","http://resolver.tudelft.nl/uuid:afc2d39f-fd74-4f66-bd3c-0b514d7791e0","An ex-ante analysis of transport impacts of a distance-based heavy goods vehicle charge in the Netherlands","de Bok, M.A. (TU Delft Transport and Planning; Significance); de Jong, Gerard (Student TU Delft; ITS Leeds); Wesseling, Bart (Significance); Meurs, Henk (MuConsult); Van Bekkum, Peter (MuConsult); Mijjer, Peter (4cast); Bakker, Dick (4cast); Veger, Teun (Rijkswaterstaat)","","2022","In 2017, the newly installed Dutch government announced in its coalition agreement to introduce a distancebased heavy goods vehicle charge, similar to the charges levied in other European countries. To study the possible transport impacts, we applied available models and methods in preparation for the introduction of this truck charge in the Netherlands in 2023, in order to present decision information to the government on different aspects of the charge. In this paper we present the analysis of different implementation scenarios for a distancebased truck charge. Different behavioural responses can be expected in terms of freight transport demand, mode choice, logistic efficiency, and route choice. Many studies however lack sufficient detail to properly describe the
impact of road charges for HGV on OD flows and freight traffic. In our contribution we explore the bandwidth of impacts of different pricing schemes, using strategic transport models for freight demand and traffic assignment,
with detailed modal split and route choice models, ensuring a proper representation of generalsed transport costs. We explain how we use available transport models in an overarching analytical framework to make a
comprehensive impact assessment of the different responses, and to decompose the impacts on the different responses. Final impacts are quantified in terms of freight demand (spatial pattern of transport flows), modal split and traffic flows (route choice, and congestion).
Depending on the pricing scenario the tonne kilometres decrease by 0.4%–4.8% on average. The modal shift impacts are stronger on longer transport distances: this is explained both by the larger impact of a distance-based charge on these routes, and by higher substitution possibilities to barge or rail. The results indicate that the overall impacts of the introduction of the different charging alternatives are moderate. However, the network impacts at local level can be substantial due to the impact of re-routing of truck trips to avoid charge.","And congestion (R41); Road pricing (R48); Supply; Transportation planning (R42); Transportation: demand","en","journal article","","","","","","","","","","","Transport and Planning","","",""
"uuid:37c1595e-53dc-4464-a792-04332d12ab6e","http://resolver.tudelft.nl/uuid:37c1595e-53dc-4464-a792-04332d12ab6e","High Frame Rate Volumetric Imaging of Microbubbles Using a Sparse Array and Spatial Coherence Beamforming","Wei, Luxi (Erasmus MC); Wahyulaksana, G. (Erasmus MC); Meijlink, Bram (Erasmus MC); Ramalli, Alessandro (University of Florence); Noothout, E.C. (TU Delft ImPhys/Medical Imaging); Verweij, M.D. (TU Delft ImPhys/Medical Imaging); van der Steen, A.F.W. (TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Vos, H.J. (TU Delft ImPhys/Medical Imaging; Erasmus MC)","","2021","Volumetric ultrasound imaging of blood flow with microbubbles enables a more complete visualization of the microvasculature. Sparse arrays are ideal candidates to perform volumetric imaging at reduced manufacturing complexity and cable count. However, due to the small number of transducer elements, sparse arrays often come with high clutter levels, especially when wide beams are transmitted to increase the frame rate. In this study, we demonstrate with a prototype sparse array probe and a diverging wave transmission strategy, that a uniform transmission field can be achieved. With the implementation of a spatial coherence beamformer, the background clutter signal can be effectively suppressed, leading to a signal to background ratio improvement of 25 dB. With this approach, we demonstrate the volumetric visualization of single microbubbles in a tissue-mimicking phantom as well as vasculature mapping in a live chicken embryo chorioallantoic membrane.","Array signal processing; Clutter; Coherence beamforming; high frame rate; Imaging; microbubbles; Signal to noise ratio; sparse array; Spatial coherence; Spirals; Ultrasonic imaging; volumetric imaging","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:aa875b32-5f8b-4fcc-b3b8-284854fca5a8","http://resolver.tudelft.nl/uuid:aa875b32-5f8b-4fcc-b3b8-284854fca5a8","The potential of biomass-derived hydrogen in west-andalusia","Van Der Slikke, Deanne (University of Seville; Student TU Delft); Guerra, Karla (University of Seville); de Jong, W. (TU Delft Large Scale Energy Storage); Haro, Pedro (University of Seville)","","2021","Hydrogen is believed to be an important energy vector in the transition to a more sustainable future. However, there is a scarcity of relevant studies analysing the realistic potential for hydrogen production in specific European regions. In this study, the potential for biomass-derived hydrogen is comprehensively analysed considering a realistic use of current biogenic residues in relevant sectors. However, not all residues can be used for the production of hydrogen and an analysis has to be made to find how much biomass is suited for hydrogen production, what amounts of hydrogen can be produced from biomass and how these amounts compare to the specific needs for renewable hydrogen in this region. This study focused on hydrogen production from agricultural residues to provide hydrogen for oil upgrading processes in petroleum refineries. The results indicate that around 92% of all agricultural residues in west-Andalusia can be used for hydrogen generation. Gasification and pyrolysis have been identified as the best candidates for the processing of the selected residues. An annual amount of 33,029 tons of biomass-based hydrogen can be used to provide 14% of the hydrogen demand for petroleum upgrading processes, thereby reducing the need natural gas in this industry.","Biomass; Gasification; Hydrogen; Integration; Residues","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2021-10-29","","","Large Scale Energy Storage","","",""
"uuid:0cd8d0c0-49e8-4163-bd95-0773075eb2ac","http://resolver.tudelft.nl/uuid:0cd8d0c0-49e8-4163-bd95-0773075eb2ac","Snel, sneller, toch niet zo snel?: Versnelling van beroep in het wetsvoorstel Versterking regie volkshuisvesting","Boeve, M.N. (TU Delft Urban Development Management); de Jong, Klaske (Universiteit van Amsterdam)","","2023","Het concept wetsvoorstel Versterking regie volkshuisvesting bevat een aantal voorstellen om de rechtsbeschermingsprocedures bij ruimtelijke projecten te versnellen. In dit artikel wordt ingegaan op de waarde van die voorstellen in het licht van reeds bestaande versnellingsmogelijkheden en toekomstige mogelijkheden onder de Omgevingswet. Daarbij worden diverse rapporten besproken en zijn interviews met juristen uit de praktijk gehouden.","","nl","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care. Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2023-10-01","","","Urban Development Management","","",""
"uuid:05e71f13-16fd-4458-8584-b9369540f39e","http://resolver.tudelft.nl/uuid:05e71f13-16fd-4458-8584-b9369540f39e","A 1.2-mW/Channel Pitch-Matched Transceiver ASIC Employing a Boxcar-Integration-Based RX Micro-Beamformer for High-Resolution 3-D Ultrasound Imaging","Guo, P. (TU Delft Bio-Electronics; TU Delft Electronic Instrumentation); Fool, F. (TU Delft ImPhys/Verweij group); Chang, Z.Y. (TU Delft Electronic Instrumentation); Noothout, E.C. (TU Delft ImPhys/Verweij group); Vos, H.J. (TU Delft ImPhys/Verweij group; Erasmus MC); Bosch, Johan G. (Erasmus MC); de Jong, N. (TU Delft ImPhys/De Jong group; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; TU Delft ImPhys/Verweij group; Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation)","","2023","This article presents a low-power and small-area transceiver application-specific integrated circuit (ASIC) for 3-D trans-fontanelle ultrasonography. A novel micro-beamforming receiver architecture that employs current-mode summation and boxcar integration is used to realize delay-and-sum on an N -element sub-array using N× fewer capacitive memory elements than conventional micro-beamforming implementations, thus reducing the hardware overhead associated with the memory elements. The boxcar integration also obviates the need for explicit anti-aliasing filtering in the analog front end, thus further reducing die area. These features facilitate the use of micro-beamforming in smaller pitch applications, as demonstrated by a prototype transceiver ASIC employing micro-beamforming on sub-arrays of N=4 elements, targeting a wearable ultrasound device that monitors brain perfusion in preterm infants via the fontanel. To meet its strict spatial resolution requirements, a 10-MHz 100- μ m-pitch piezoelectric transducer array is employed, leading to a per-element die area > 2 × smaller than prior designs employing micro-beamforming.","Application-specific integrated circuit (ASIC); micro-beamformer ( $\mu$ BF); pitch-matched analog front end (AFE); sub-array beamforming","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2023-11-27","","","Bio-Electronics","","",""
"uuid:67f69fd2-d81f-40cb-a207-e6a96584b8ca","http://resolver.tudelft.nl/uuid:67f69fd2-d81f-40cb-a207-e6a96584b8ca","The societal strength of transition: a critical review of the circular economy through the lens of inclusion","Liu, Z. (TU Delft Integral Design & Management); Schraven, D.F.J. (TU Delft Integral Design & Management); de Jong, Martin (Erasmus Universiteit Rotterdam; Fudan University); Hertogh, M.J.C.M. (TU Delft Integral Design & Management; Erasmus Universiteit Rotterdam)","","2023","Realizing a circular economy (CE) has been widely recognized by practitioners and researchers as the key to the transition toward sustainability. Thus far the academic emphasis has been predominantly on economic and environmental aspects. However, the development and implementation of CE initiatives actually rely on extensive collaboration at the societal level. Hence, an understanding of how a more inclusive society can strengthen the transition is warranted. By systematically and critically reviewing the related academic literature, the results of this paper show that sensitivity to inclusion aspects is crucial to alleviate the transitional burdens on society. Seven main aspects were discerned on inclusion: (1) informal waste pickers, (2) e-waste and health risks, (3) accessibility of services/materials/facilities, (4) consumer behavior, (5) corporate and institutional involvement, (6) technology application, and (7) governance measures. Following these insights, a strong sustainability perspective and agenda on the CE transition are proposed by identifying key actors and structuring their interrelationships as an inclusive system.","circular economy; Inclusion; informal sector; strong sustainability; waste management","en","journal article","","","","","","","","","","","Integral Design & Management","","",""
"uuid:10788f03-eaeb-4f13-a148-d46122f1be8d","http://resolver.tudelft.nl/uuid:10788f03-eaeb-4f13-a148-d46122f1be8d","Predicting the mechanical hip–knee–ankle angle accurately from standard knee radiographs: a cross-validation experiment in 100 patients","Gielis, Willem Paul (University Medical Center Utrecht); Rayegan, Hassan (University of Birjand); Arbabi, V. (TU Delft Biomaterials & Tissue Biomechanics; University Medical Center Utrecht); Ahmadi Brooghani, Seyed Y. (University of Birjand); Lindner, Claudia (The University of Manchester); Cootes, Tim F. (The University of Manchester); de Jong, Pim A. (University Medical Center Utrecht; Universiteit Utrecht); Weinans, Harrie (University Medical Center Utrecht); Custers, Roel J.H. (University Medical Center Utrecht)","","2020","Background and purpose — Being able to predict the hip–knee–ankle angle (HKAA) from standard knee radiographs allows studies on malalignment in cohorts lacking full-limb radiography. We aimed to develop an automated image analysis pipeline to measure the femoro-tibial angle (FTA) from standard knee radiographs and test various FTA definitions to predict the HKAA. Patients and methods — We included 110 pairs of standard knee and full-limb radiographs. Automatic search algorithms found anatomic landmarks on standard knee radiographs. Based on these landmarks, the FTA was automatically calculated according to 9 different definitions (6 described in the literature and 3 newly developed). Pearson and intra-class correlation coefficient [ICC]) were determined between the FTA and HKAA as measured on full-limb radiographs. Subsequently, the top 4 FTA definitions were used to predict the HKAA in a 5-fold cross-validation setting. Results — Across all pairs of images, the Pearson correlations between FTA and HKAA ranged between 0.83 and 0.90. The ICC values from 0.83 to 0.90. In the cross-validation experiments to predict the HKAA, these values decreased only minimally. The mean absolute error for the best method to predict the HKAA from standard knee radiographs was 1.8° (SD 1.3). Interpretation — We showed that the HKAA can be automatically predicted from standard knee radiographs with fair accuracy and high correlation compared with the true HKAA. Therefore, this method enables research of the relationship between malalignment and knee pathology in large (epidemiological) studies lacking full-limb radiography.","","en","journal article","","","","","","","","","","","Biomaterials & Tissue Biomechanics","","",""
"uuid:37fd9b75-bfd4-4550-956f-d6a81f9f3be8","http://resolver.tudelft.nl/uuid:37fd9b75-bfd4-4550-956f-d6a81f9f3be8","The Future of Burn Care From a Complexity Science Perspective","van Zuijlen, Paul P.M. (Red Cross Hospital, Beverwijk; Amsterdam Movement Sciences; Emma Children's Hospital Academic Medical Center, University of Amsterdam); Korkmaz, Halil Ibrahim (Red Cross Hospital, Beverwijk; Amsterdam Movement Sciences; Association of Dutch Burn Centres (ADBC)); Sheraton, Vivek M. (Universiteit van Amsterdam); Haanstra, Tsjitske M. (National Health Care Institute (Zorginstituut Nederland)); Pijpe, Anouk (Red Cross Hospital, Beverwijk); de Vries, Annebeth (Red Cross Hospital, Beverwijk; Emma Children's Hospital Academic Medical Center, University of Amsterdam); van der Vlies, Cornelis H. (Erasmus MC; Maasstad Ziekenhuis); Bosma, Eelke (Martini Ziekenhuis); de Jong, Evelien (Red Cross Hospital, Beverwijk); Middelkoop, Esther (Red Cross Hospital, Beverwijk; Amsterdam Movement Sciences; Association of Dutch Burn Centres (ADBC)); Vermolen, F.J. (TU Delft Numerical Analysis; University of Hasselt); Sloot, Peter M.A. (Universiteit van Amsterdam; Complexity Institute; ITMO University)","","2022","Health care is undergoing a profound technological and digital transformation and has become increasingly complex. It is important for burns professionals and researchers to adapt to these developments which may require new ways of thinking and subsequent new strategies. As Einstein has put it: ""We must learn to see the world anew."" The relatively new scientific discipline ""Complexity science"" can give more direction to this and is the metaphorical open door that should not go unnoticed in view of the burn care of the future. Complexity science studies ""why the whole is more than the sum of the parts."" It studies how multiple separate components interact with each other and their environment and how these interactions lead to ""behavior of the system."" Biological systems are always part of smaller and larger systems and exhibit the behavior of adaptivity, hence the name complex adaptive systems. From the perspective of complexity science, a severe burn injury is an extreme disruption of the ""human body system."" But this disruption also applies to the systems at the organ and cellular levels. All these systems follow the principles of complex systems. Awareness of the scaling process at multilevel helps to understand and manage the complex situation when dealing with severe burn cases. This paper aims to create awareness of the concept of complexity and to demonstrate the value and possibilities of complexity science methods and tools for the future of burn care through examples from preclinical, clinical, and organizational perspectives in burn care.","","en","journal article","","","","","","","","","","","Numerical Analysis","","",""
"uuid:0417087e-2e2e-4130-81eb-4de9a38b9b43","http://resolver.tudelft.nl/uuid:0417087e-2e2e-4130-81eb-4de9a38b9b43","Transit-Oriented Development in China: A Comparative Content Analysis of the Spatial Plans of High-Speed Railway Station Areas","Wang, B. (TU Delft Urban Development Management); de Jong, Martin (Fudan University; Erasmus Universiteit Rotterdam); van Bueren, Ellen (TU Delft Management in the Built Environment); Ersoy, A. (TU Delft Urban Development Management); Meng, Yanchun (Tsinghua University)","","2023","With rapid high-speed railway (HSR) developments in China, HSR-based transit-oriented development (TOD) has proliferated across the country. Although local governments claim that HSR station areas are planned according to TOD principles, some scholars argue that these station areas actually contribute to unsustainable development. This study investigates two main questions: (1) what success factors should be included in a TOD plan for HSR station areas? (2) to what extent are these factors considered in the plans of Chinese HSR station areas? To answer these questions, we use content analysis to compare spatial plans for 15 HSR station areas across China, triangulating the findings via in-depth interviews and field investigations. This study reveals that most of the factors in the plans for HSR station areas deviate from TOD principles, especially in small- and medium-sized cities. We find that Chinese local governments mainly use TODs as a tool to promote suburban expansion around HSR stations.","TOD; high-speed railway; station area; spatial plan; content analysis","en","journal article","","","","","","","","","","Management in the Built Environment","Urban Development Management","","",""
"uuid:2c68a183-201b-4450-8664-59fc9c397ae3","http://resolver.tudelft.nl/uuid:2c68a183-201b-4450-8664-59fc9c397ae3","Past, present, future: Engagement with sustainable urban development through 35 city labels in the scientific literature 1990–2019","Schraven, D.F.J. (TU Delft Integral Design & Management); Joss, Simon (University of Glasgow); de Jong, Martin (Erasmus Universiteit Rotterdam; Fudan University)","","2021","SDG 11 – ‘making cities and human settlements inclusive, safe, resilient and sustainable’ – draws attention to the criticality of urban governance in the quest for sustainable development. Reflecting this, diverse city labels, such as ‘sustainable city’ and ‘smart city’, have been mobilized by urban actors and scholars to consider cities’ responses to various challenges of urban transformation. Consequently, this study interrogates: (1) the growing use of city labels in the scientific literature over three decades; (2) the conceptual dimensions of individual city labels and their mutual interdependencies; and (3) likely future trajectories. This is accomplished through a comprehensive bibliometric analysis of 35 city labels: we examine their (co-)occurrences during 1990–2019 based on 11337 articles harvested in Scopus; analyse their conceptual associations drawing on a corpus of 22820 author keywords; and make a future forecast based on logistic growth modelling (the underlying datasets are available through open access). The findings significantly take forward recent bibliometric research by demonstrating: the rapid growth in scientific outputs; the diversification of city labels beyond ‘smart’ and ‘sustainable’; and the evolution of an intricate conceptual field made up of different constellations of city labels. The findings have implications for urban policy and practice: regarding ongoing concerns about how to achieve synergies, rather than trade-offs, between SDGs, the conceptual field points to possible ways for relating SDG 11 to other dimensions of sustainable development. More broadly, the clarification of individual city labels’ conceptual underpinnings should help policymakers and practitioners make considered choices when mobilizing city labels in support of urban transformation efforts.","Bibliometrics; Cities; City label; Smart city; Sustainable city; Sustainable development","en","journal article","","","","","","Accepted author manuscript","","2022-01-29","","","Integral Design & Management","","",""
"uuid:2aff786f-35b1-42ad-9065-2837a77e75a8","http://resolver.tudelft.nl/uuid:2aff786f-35b1-42ad-9065-2837a77e75a8","Modeling the Performance of an Integrated Battery and Electrolyzer System","Mangel Raventos, A. (TU Delft Large Scale Energy Storage); Kluivers, Gerard J. (Student TU Delft); Haverkort, J.W. (TU Delft Energy Technology); de Jong, W. (TU Delft Large Scale Energy Storage); Mulder, F.M. (TU Delft ChemE/Materials for Energy Conversion and Storage); Kortlever, R. (TU Delft Large Scale Energy Storage)","","2021","Both daily and seasonal fluctuations of renewable power sources will require large-scale energy storage technologies. A recently developed integrated battery and electrolyzer system, called battolyser, fulfills both time-scale requirements. Here, we develop a macroscopic COMSOL Multiphysics model to quantify the energetic efficiency of the battolyser prototype that, for the first time, integrates the functionality of a nickel-iron battery and an alkaline electrolyzer. The current prototype has a rated capacity of 5 Ah, and to develop a larger, enhanced system, it is necessary to characterize the processes occurring within the battolyser and to optimize the individual components of the battolyser. Therefore, there is a need for a model that can provide a fast screening on how the properties of individual components influence the overall energy efficiency of the battolyser prototype. The model is validated using experimental results, and new configurations are compared, and the energy efficiency is optimized for the scale-up of this lab-scale device. Based on the modeling work, we find an optimum electrode thickness for the nickel electrode of 3 and 2.25 mm for the iron electrode with optimal electrode porosities in the range of void fraction of 0.15-0.35. Additionally, electrolyte conductivity and the gap thickness are found to have a small effect on the overall efficiency of the device.","","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:73c80337-0eaf-4cab-aae2-753d17522789","http://resolver.tudelft.nl/uuid:73c80337-0eaf-4cab-aae2-753d17522789","Magnetic-Field-Resilient Superconducting Coplanar-Waveguide Resonators for Hybrid Circuit Quantum Electrodynamics Experiments","Kroll, J. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Borsoi, F. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); van der Enden, K.L. (TU Delft Applied Sciences; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Uilhoorn, W. (TU Delft QRD/Kouwenhoven Lab; Kavli institute of nanoscience Delft); de Jong, D. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Quintero Perez, M. (TU Delft BUS/General; TU Delft QuTech Advanced Research Centre; TNO); van Woerkom, D.J. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Bruno, A. (TU Delft QCD/DiCarlo Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Plissard, S. R. (Eindhoven University of Technology); Car, D. (Eindhoven University of Technology); Bakkers, E.P.A.M. (Eindhoven University of Technology); Cassidy, M.C. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; ENSIACET; Kavli institute of nanoscience Delft); Kouwenhoven, Leo P. (TU Delft QRD/Kouwenhoven Lab; TU Delft QN/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Microsoft Quantum Lab Delft)","","2019","Superconducting coplanar-waveguide resonators that can operate in strong magnetic fields are important tools for a variety of high-frequency superconducting devices. Magnetic fields degrade resonator performance by creating Abrikosov vortices that cause resistive losses and frequency fluctuations or suppress the superconductivity entirely. To mitigate these effects, we investigate lithographically defined artificial defects in resonators fabricated from Nb-Ti-N superconducting films. We show that by controlling the vortex dynamics, the quality factor of resonators in perpendicular magnetic fields can be greatly enhanced. Coupled with the restriction of the device geometry to enhance the superconductors critical field, we demonstrate stable resonances that retain quality factors ≃105 at the single-photon power level in perpendicular magnetic fields up to B⊥ ≃20mT and parallel magnetic fields up to B⥠≃6T. We demonstrate the effectiveness of this technique for hybrid systems by integrating an In-Sb nanowire into a field-resilient superconducting resonator and use it to perform fast charge readout of a gate-defined double quantum dot at B=1T.","","en","journal article","","","","","","","","","Applied Sciences","","QRD/Kouwenhoven Lab","","",""
"uuid:6aad39c0-6fb2-4c72-817c-9b2e83d706d9","http://resolver.tudelft.nl/uuid:6aad39c0-6fb2-4c72-817c-9b2e83d706d9","Big data of the past: Analysis of historical freight shipping corridor data in the period 1662–1855","Wiegmans, B. (TU Delft Transport and Planning); Witte, Patrick (Universiteit Utrecht); Janic, M. (TU Delft Transport and Planning); de Jong, Tom (Stellenbosch University)","","2020","This paper examines the use of big data and data analytics in international transport networks from the perspective of historical big data, focusing on shipping logs from the British, Dutch, Spanish and French fleets in between 1662 and 1855. Based on a large-scale database containing mainly meteorological data collected in the CLIWOC project (2003), we computed travel distances and analyzed historical global maritime networks. This paper focuses on route choice, and consequently the time, distance, speed and reliability of the ships, covering different time periods, seasonal patterns and trade flows. The results reveal a clear picture of the main routes per nationality that is also indicative of the linguistical, cultural and economic colonial heritage that remains in the ‘host’ countries up to this day. The average daily distances covered vary over the countries involved, over the seasons and over different time periods. Also the trip characteristics vary notably over the different countries. Zooming in on the main trade flows, the corridor from the Netherlands to Indonesia stands out, but also considerable differences in average speed and stopover times were found along this route. Related to the complexity of using big data in studying international transport networks, our conclusion is that the degree of permutations and interactions with the dataset is not necessarily less for analyzing historical shipping records. It seems that big data of the past still can inspire future explorations of our historical transport networks on the world's oceans.","CLIWOC; Corridors; Data analysis; Historical freight data; Reliability; Time","en","journal article","","","","","","Accepted Author Manuscript","","2022-06-15","","","Transport and Planning","","",""
"uuid:ea441ea0-288a-4ed2-b5a3-d61c96688405","http://resolver.tudelft.nl/uuid:ea441ea0-288a-4ed2-b5a3-d61c96688405","Combining ultrafast ultrasound and high-density EMG to assess local electromechanical muscle dynamics: a feasibility study","Waasdorp, R. (TU Delft ImPhys/Medical Imaging); Mugge, W. (TU Delft Biomechatronics & Human-Machine Control); Vos, H.J. (TU Delft ImPhys/Medical Imaging; Erasmus MC); De Groot, Jurriaan H. (Leiden University Medical Center); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Schouten, A.C. (TU Delft Biomechatronics & Human-Machine Control; University of Twente); Daeichin, V. (TU Delft ImPhys/Medical Imaging; Kaminari Medical, Rotterdam)","","2021","Skeletal muscles generate force, enabling movement through a series of fast electro-mechanical activations coordinated by the central nervous system. Understanding the underlying mechanism of such fast muscle dynamics is essential in neuromuscular diagnostics, rehabilitation medicine and sports biomechanics. The unique combination of electromyography (EMG) and ultrafast ultrasound imaging (UUI) provides valuable insights into both electrical and mechanical activity of muscle fibers simultaneously, the excitation-contraction (E-C) coupling. In this feasibility study we propose a novel non-invasive method to simultaneously track the propagation of both electrical and mechanical waves in muscles using high-density electromyography and ultrafast ultrasound imaging (5000 fps). Mechanical waves were extracted from the data through an axial tissue velocity estimator based on one-lag autocorrelation. The E-C coupling in electrically evoked twitch contractions of the Biceps Brachii in healthy participants could successfully be tracked. The excitation wave (i.e. action potential) had a velocity of 3.9±0.5ms-1 and the subsequent mechanical (i.e. contraction) wave had a velocity of 3.5±0.9ms-1. The experiment showed evidence that contracting sarcomeres that were already activated by the action potential (AP) pull on sarcomeres that were not yet reached by the AP, which was corroborated by simulated contractions of a newly developed multisegmental muscle fiber model, consisting of 500 sarcomeres in series. In conclusion, our method can track the electromechanical muscle dynamics with high spatio-temporal resolution. Ultimately, characterizing E-C coupling in patients with neuromuscular diseases (e.g. Duchenne or Becker muscular dystrophy) may assess contraction efficiency, monitor the progression of the disease, and determine the efficacy of new treatment options.","Action potentials; Couplings; Electromyography; electrostimulation; excitation-contraction coupling; Force; high-density electromyography; Hill model; latency relaxation; multisegmental modeling; muscle modeling; Muscles; speckle-tracking; Transducers; Ultrafast ultrasound; Ultrasonic imaging; wave tracking","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:41de3af3-5f1b-44e3-a257-5b4fc2e1973b","http://resolver.tudelft.nl/uuid:41de3af3-5f1b-44e3-a257-5b4fc2e1973b","Rapid Microwave-Only Characterization and Readout of Quantum Dots Using Multiplexed Gigahertz-Frequency Resonators","de Jong, D. (TU Delft QRD/Kouwenhoven Lab); Prosko, C.G. (TU Delft QRD/Kouwenhoven Lab); Waardenburg, D.M.A. (TU Delft QRD/Kouwenhoven Lab); Han, L. (TU Delft QRD/Kouwenhoven Lab); Malinowski, F.K. (TU Delft QRD/Kouwenhoven Lab); Krogstrup, P. (University of Copenhagen); Kouwenhoven, Leo P. (TU Delft QN/Kouwenhoven Lab); Koski, J.V. (TU Delft BUS/Quantum Delft); Pfaff, W. (TU Delft QRD/Kouwenhoven Lab; University of Illinois at Urbana-Champaign)","","2021","Superconducting resonators enable fast characterization and readout of mesoscopic quantum devices. Finding ways to perform measurements of interest on such devices using resonators only is therefore of great practical relevance. We report an experimental investigation of an InAs nanowire multiquantum dot device by probing gigahertz resonators connected to the device. First, we demonstrate accurate extraction of the dc conductance from measurements of the high-frequency admittance. Because our technique does not rely on dc calibration, it could potentially obviate the need for dc measurements in semiconductor qubit devices. Second, we demonstrate multiplexed gate sensing and the detection of charge tunneling on microsecond timescales. The gigahertz detection of dispersive resonator shifts allows rapid acquisition of charge stability diagrams, as well as resolving charge tunneling in the device with a signal-to-noise ratio of up to 15 in 1μs. Our measurements show that gigahertz-frequency resonators may serve as a universal tool for fast tuneup and high-fidelity readout of semiconductor qubits.","","en","journal article","","","","","","","","","","","QRD/Kouwenhoven Lab","","",""
"uuid:af73613e-3ba4-44c2-b0b3-c091e104903d","http://resolver.tudelft.nl/uuid:af73613e-3ba4-44c2-b0b3-c091e104903d","High pressure electrochemical reduction of CO2 to formic acid/formate: A comparison between bipolar membranes and cation exchange membranes","Ramdin, M. (TU Delft Engineering Thermodynamics); Morrison, A.R.T. (TU Delft Large Scale Energy Storage); de Groen, M. (Coval Energy); van Haperen, M.C.H. (Coval Energy); De Kler, Robert (Coval Energy); van den Broeke, L.J.P. (Coval Energy); Trusler, J. P.Martin (Imperial College London); de Jong, W. (TU Delft Large Scale Energy Storage); Vlugt, T.J.H. (TU Delft Engineering Thermodynamics)","","2019","A high pressure semicontinuous batch electrolyzer is used to convert CO2 to formic acid/formate on a tin-based cathode using bipolar membranes (BPMs) and cation exchange membranes (CEMs). The effects of CO2 pressure up to 50 bar, electrolyte concentration, flow rate, cell potential, and the two types of membranes on the current density (CD) and Faraday efficiency (FE) for formic acid/formate are investigated. Increasing the CO2 pressure yields a high FE up to 90% at a cell potential of 3.5 V and a CD of ∼30 mA/cm2. The FE decreases significantly at higher cell potentials and current densities, and lower pressures. Up to 2 wt % formate was produced at a cell potential of 4 V, a CD of ∼100 mA/cm2, and a FE of 65%. The advantages and disadvantages of using BPMs and CEMs in electrochemical cells for CO2 conversion to formic acid/formate are discussed.","","en","journal article","","","","","","","","","","","Engineering Thermodynamics","","",""
"uuid:e95574c9-35e0-4c24-b006-fc8ade3fa0a0","http://resolver.tudelft.nl/uuid:e95574c9-35e0-4c24-b006-fc8ade3fa0a0","Controllable Single Cooper Pair Splitting in Hybrid Quantum Dot Systems","de Jong, D. (TU Delft BUS/Quantum Delft; Kavli institute of nanoscience Delft; QuTech); Prosko, C.G. (TU Delft QRD/Kouwenhoven Lab; Kavli institute of nanoscience Delft; QuTech); Han, L. (TU Delft QRD/Wimmer Group; Kavli institute of nanoscience Delft; QuTech); Malinowski, F.K. (TU Delft BUS/TNO STAFF; Kavli institute of nanoscience Delft; QuTech); Liu, Yu (University of Copenhagen); Kouwenhoven, Leo P. (TU Delft QN/Kouwenhoven Lab; Kavli institute of nanoscience Delft; QuTech); Pfaff, Wolfgang (University of Illinois at Urbana-Champaign)","","2023","Cooper pair splitters hold utility as a platform for investigating the entanglement of electrons in Cooper pairs, but probing splitters with voltage-biased Ohmic contacts prevents the retention of electrons from split pairs since they can escape to the drain reservoirs. We report the ability to controllably split and retain single Cooper pairs in a multi-quantum-dot device isolated from lead reservoirs, and separately demonstrate a technique for detecting the electrons emerging from a split pair. First, we identify a coherent Cooper pair splitting charge transition using dispersive gate sensing at GHz frequencies. Second, we utilize a double quantum dot as an electron parity sensor to detect parity changes resulting from electrons emerging from a superconducting island.","","en","journal article","","","","","","","","","","","BUS/Quantum Delft","","",""
"uuid:c95bf0d6-ff24-4ff0-8c6c-3b196d30b566","http://resolver.tudelft.nl/uuid:c95bf0d6-ff24-4ff0-8c6c-3b196d30b566","Focal areas of increased lipid concentration on the coating of microbubbles during short tone-burst ultrasound insonification","Kooiman, Klazina (University of Pittsburgh Medical Center; Netherlands Heart Institute; Erasmus MC); van Rooij, Tom (Erasmus MC); Qin, Bin (University of Pittsburgh Medical Center); Mastik, Frits (Erasmus MC); Vos, H.J. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Versluis, Michel (University of Twente); Klibanov, Alexander L. (University of Virginia); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Villanueva, Flordeliza S. (University of Pittsburgh Medical Center); Chen, Xucai (University of Pittsburgh Medical Center)","","2017","Acoustic behavior of lipid-coated microbubbles has been widely studied, which has led to several numerical microbubble dynamics models that incorporate lipid coating behavior, such as buckling and rupture. In this study we investigated the relationship between micro-bubble acoustic and lipid coating behavior on a nanosecond scale by using fluorescently labeled lipids. It is hypothesized that a local increased concentration of lipids, appearing as a focal area of increased fluorescence intensity (hot spot) in the fluorescence image, is related to buckling and folding of the lipid layer thereby highly influencing the microbubble acoustic behavior. To test this hypothesis, the lipid microbubble coating was fluorescently labeled. The vibration of the microbubble (n= 177; 2.3-10.3 μm in diameter) upon insonification at an ultrasound frequency of 0.5 or 1 MHz at 25 or 50 kPa acoustic pressure was recorded with the UPMC Cam, an ultra-high-speed fluorescence camera, operated at ∼4-5 million frames per second. During short tone-burst excitation, hot spots on the microbubble coating occurred at relative vibration amplitudes > 0.3 irrespective of frequency and acoustic pressure. Around resonance, the majority of the microbubbles formed hot spots. When the microbubble also deflated acoustically, hot spot formation was likely irreversible. Although compression-only behavior (defined as substantially more microbubble compression than expansion) and subharmonic responses were observed in those microbubbles that formed hot spots, both phenomena were also found in microbubbles that did not form hot spots during insonification. In conclusion, this study reveals hot spot formation of the lipid monolayer in the microbubble's compression phase. However, our experimental results show that there is no direct relationship between hot spot formation of the lipid coating and microbubble acoustic behaviors such as compression-only and the generation of a subharmonic response. Hence, our hypothesis that hot spots are related to acoustic buckling could not be verified.","","en","journal article","","","","","","","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:d517ca1c-d7c3-49ad-92a9-5dbec4cad334","http://resolver.tudelft.nl/uuid:d517ca1c-d7c3-49ad-92a9-5dbec4cad334","Microstructural degradation during the storage of biomass pellets","Cutz, L. (TU Delft Large Scale Energy Storage); Tiringer, U. (TU Delft Team Arjan Mol); Gilvari, H. (TU Delft Large Scale Energy Storage); Schott, D.L. (TU Delft Transport Engineering and Logistics); Mol, J.M.C. (TU Delft Team Arjan Mol); de Jong, W. (TU Delft Large Scale Energy Storage)","","2021","The use of biomass pellets as a source of renewable energy has increased in recent times. However, pellet storage during transportation can compromise their properties, due to fluctuating temperature and humid environments. Here, we show that extended storage of one month at 40 °C and 85% relative humidity causes significant biomass pellet degradation. This was evidenced by higher pellet porosity, weight gain, increased inclusion body formation and creation of an internal network of cracks. We quantify the inclusion and pore growth processes at the surface and within the pellets, which has implications for subsequent thermochemical conversion. The global bioenergy transition may depend upon biomass pellets, and this study shows that storage conditions are critical in the supply chain, so to maintain their quality. Without the development of stronger policies to avoid premature degradation of biomass pellets, they may not realize their full potential as a bioenergy source.","","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:bbf1c0ce-4da2-4467-9681-b82bc9bd3a1d","http://resolver.tudelft.nl/uuid:bbf1c0ce-4da2-4467-9681-b82bc9bd3a1d","Effects of fir-wood biochar on CH4 oxidation rates and methanotrophs in landfill cover soils packed at three different proctor compaction levels","Buisma-Yi, S.C. (TU Delft Geo-engineering); Heijbroek, A.C. (TU Delft Geo-engineering); Cutz, L. (TU Delft Large Scale Energy Storage); Pillay, S. (TU Delft Pattern Recognition and Bioinformatics); de Jong, W. (TU Delft Large Scale Energy Storage); Abeel, T.E.P.M.F. (TU Delft Pattern Recognition and Bioinformatics; Broad Institute of MIT and Harvard); Gebert, J. (TU Delft Geo-engineering)","","2023","Application of biochar to landfill cover soils can purportedly improve methane (CH4) oxidation rates, but understanding the combined effects of soil texture, compaction, and biochar on the activity and composition of the methanotrophs is limited. The amendment of wood biochar on two differently textured landfill cover soils at three compaction levels of the Proctor density was explored by analyzing changes in soil physical properties relevant to methane oxidation, the effects on CH4 oxidation rates, and the composition of the methanotrophic community. Loose soils with and without biochar were pre-incubated to equally elevate the CH4 oxidation rates. Hereafter, soils were compacted and re-incubated. Methane oxidation rates, gas diffusivity, water retention characteristics, and pore size distribution were analyzed on the compacted soils. The relative abundance of methanotrophic bacteria (MOB) was determined at the end of both the pre-incubation and incubation tests of the packed samples. Biochar significantly increased porosity at all compaction levels, enhancing diffusion coefficients. Also, a re-distribution in pore sizes was observed. Increased gas diffusivity from low compaction and amendment of biochar, though, did not reflect higher methane oxidation rates due to high diffusive oxygen fluxes over the limited height of the compacted soil specimens. All soils, with and without biochar, were strongly dominated by Type II methanotrophs. In the sandy soil, biochar amendment strongly increased MOB abundance, which could be attributed to a corresponding increase in the relative abundance of Methylocystis species, while no such response was observed in the clayey soil. Compaction did not change the community composition in either soil. Fir-wood biochar addition to landfill cover soils may not always enhance methanotrophic activity and hence reduce fugitive methane emissions, with the effect being soil-specific. However, especially in finer and more compacted soils, biochar amendment can maintain soil diffusivity above a critical level, preventing the collapse of methanotrophy.","Biochar; Proctor compaction; Gas transport; Landfill cover soil; Methane oxidation; Soil properties; Pore size distribution; Methanotrophs","en","journal article","","","","","","","","","","","Geo-engineering","","",""
"uuid:1b67fca8-a8f9-4402-863c-ba066797ee48","http://resolver.tudelft.nl/uuid:1b67fca8-a8f9-4402-863c-ba066797ee48","A novel viral infection model to guide optimal mpox treatment","de Jong, M.N. (TU Delft Team Tamas Keviczky); Campana, Francesca Cala (Università di Trento); Li, Pengfei (Erasmus MC); Pan, Qiuwei (Erasmus MC); Giordano, G. (Università di Trento)","","2023","In 2022, worldwide mpox outbreaks have called attention to mpox virus infection and treatment opportunities using the drugs cidofovir and tecovirimat, which target different stages of in-host viral proliferation, respectively production and shedding. We propose a new model of in-host viral infection dynamics that distinguishes between the two stages, so as to explore the distinct effects of the two drugs, and we analyse the model properties and behaviour. Reducing the model order via timescale separation is shown to lead to the classical target-cell limited model, with a lumped viral proliferation rate depending on both production and shedding. We explicitly introduce the effect of the two drugs and we exemplify how to formulate and solve an optimal control problem that leverages the model dynamics to schedule optimal combined treatments.","Analytical models; Antiviral therapies; Coronaviruses; Drugs; Extracellular; In-host models; Infection models; Infectious diseases; Optimal control; Production; Sociology; Statistics","en","journal article","","","","","","","","","","","Team Tamas Keviczky","","",""
"uuid:b70b096f-8404-4d8f-8c92-5fa93be0ec9e","http://resolver.tudelft.nl/uuid:b70b096f-8404-4d8f-8c92-5fa93be0ec9e","A Quantitative Analysis of Electrochemical CO2 Reduction on Copper in Organic Amide and Nitrile-Based Electrolytes","Sajeev Kumar, A. (TU Delft Large Scale Energy Storage); Moura de Salles Pupo, M. (TU Delft Large Scale Energy Storage); Petrov, K.V. (TU Delft ChemE/Transport Phenomena); Ramdin, M. (TU Delft Engineering Thermodynamics); van Ommen, J.R. (TU Delft ChemE/Product and Process Engineering); de Jong, W. (TU Delft Large Scale Energy Storage); Kortlever, R. (TU Delft Large Scale Energy Storage)","","2023","Aqueous electrolytes used in CO2 electroreduction typically have a CO2 solubility of around 34 mM under ambient conditions, contributing to mass transfer limitations in the system. Non-aqueous electrolytes exhibit higher CO2 solubility (by 5–8-fold) and also provide possibilities to suppress the undesired hydrogen evolution reaction (HER). On the other hand, a proton donor is needed to produce many of the products commonly obtained with aqueous electrolytes. This work investigates the electrochemical CO2 reduction performance of copper in non-aqueous electrolytes based on dimethylformamide (DMF), n-methyl-2-pyrrolidone (NMP), and acetonitrile (ACN). The main objective is to analyze whether non-aqueous electrolytes are a viable alternative to aqueous electrolytes for hydrocarbon production. Additionally, the effects of aqueous/non-aqueous anolytes, membrane, and the selection of a potential window on the electrochemical CO2 reduction performance are addressed in this study. Experiments with pure DMF and NMP mainly produced oxalate with a faradaic efficiency (FE) reaching >80%; however, pure ACN mainly produced hydrogen and formate due to the presence of more residual water in the system. Addition of 5% (v/v) water to the non-aqueous electrolytes resulted in increased HER and formate production with negligible hydrocarbon production. Hence, we conclude that aqueous electrolytes remain a better choice for the production of hydrocarbons and alcohols on a copper electrode, while organic electrolytes based on DMF and NMP can be used to obtain a high selectivity toward oxalate and formate.","CO2 electroreduction; non-aqueous electrolytes; copper electrode; electrolyte effects; water effects","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:dc6d3c17-d44b-46ea-9398-03e4c75b7541","http://resolver.tudelft.nl/uuid:dc6d3c17-d44b-46ea-9398-03e4c75b7541","Higher Order Singular Value Decomposition Filter for Contrast Echocardiography","Wahyulaksana, G. (Erasmus MC); Wei, Luxi (Erasmus MC); Voorneveld, J.D. (Erasmus MC); Hekkert, Maaike Te Lintel (Erasmus MC); Strachinaru, Mihai (Erasmus MC); Duncker, Dirk J. (Erasmus MC); de Jong, N. (TU Delft ImPhys/De Jong group; Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Medical Imaging; TU Delft ImPhys/Verweij group; Erasmus MC); Vos, H.J. (TU Delft ImPhys/Verweij group; Erasmus MC)","","2023","Assessing the coronary circulation with contrast-enhanced echocardiography has high clinical relevance. However, it is not being routinely performed in clinical practice because the current clinical tools generally cannot provide adequate image quality. The contrast agent's visibility in the myocardium is generally poor, impaired by motion and nonlinear propagation artifacts. The established multipulse contrast schemes (MPCSs) and the more experimental singular value decomposition (SVD) filter also fall short to solve these issues. Here, we propose a scheme to process amplitude modulation/amplitude-modulated pulse inversion (AM/AMPI) echoes with higher order SVD (HOSVD) instead of conventionally summing the complementary pulses. The echoes from the complementary pulses form a separate dimension in the HOSVD algorithm. Then, removing the ranks in that dimension with dominant coherent signals coming from tissue scattering would provide the contrast detection. We performed both in vitro and in vivo experiments to assess the performance of our proposed method in comparison with the current standard methods. A flow phantom study shows that HOSVD on AM pulsing exceeds the contrast-to-background ratio (CBR) of conventional AM and an SVD filter by 10 and 14 dB, respectively. In vivo porcine heart results also demonstrate that, compared to AM, HOSVD improves CBR in open-chest acquisition (up to 19 dB) and contrast ratio (CR) in closed-chest acquisition (3 dB).","Contrast-enhanced ultrasound (CEUS); higher order singular value decomposition (HOSVD); microbubble detection; myocardial perfusion; ultrafast imaging","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:0f09051f-eafc-401f-898c-2733bdaaec88","http://resolver.tudelft.nl/uuid:0f09051f-eafc-401f-898c-2733bdaaec88","Modelling Lamb waves in the septal wall of the heart","Sabbadini, A. (TU Delft ImPhys/Acoustical Wavefield Imaging); Caenen, A.F.M. (Erasmus MC); Vos, H.J. (Erasmus MC); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging); Verweij, M.D. (TU Delft ImPhys/Acoustical Wavefield Imaging)","","2019","Shear Wave Elastography (SWE) has been proposed to investigate cardiac health by non-invasively monitoring tissue stiffness. Previous work has shown that the plate-like geometry of the Interventricular Septum (IVS) may result in a dispersion similar to Lamb waves, complicating the link between shear wave speed and cardiac stiffness. However, the IVS is not a simple plate, e.g., its thickness tapers across its length. We have used 2-D Finite Element simulations to investigate the effects of tapering on Lamb waves. The model consists of an elastic slab immersed in water, with a thickness decreasing smoothly in space from 9 to 3 mm. Pulses with low (0–80 Hz) and high (0–700 Hz) frequency contents were used to excite natural and acoustic radiation force induced waves. The results show that, at the lower frequencies, propagation speed can decrease during propagation by ~20% due to the thickness reduction, producing a nonlinear space-time relation from which multiple speed values can be extracted. At higher frequencies, the main observation is a dependence of the dispersion behavior on the shape of the tapering (e.g., linear, concave, or convex). These results suggest that septal geometry is likely to play a role in deriving cardiac stiffness from propagation speed measurements.","","en","journal article","","","","","","","","2020-09-01","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:814e81f6-8bac-431b-8a44-90692fdbe9ad","http://resolver.tudelft.nl/uuid:814e81f6-8bac-431b-8a44-90692fdbe9ad","Input-Output Modeling for Smart City Development","Noori, Negar (Erasmus Universiteit Rotterdam); de Jong, Martin (Erasmus Universiteit Rotterdam; Fudan University); Janssen, M.F.W.H.A. (TU Delft Information and Communication Technology); Schraven, D.F.J. (TU Delft Integral Design & Management); Hoppe, T. (TU Delft Organisation & Governance)","","2020","While many national and local governments in the world are placing their bets on smart city development in countering challenges such as climate change, air pollution, and congestion, few know exactly how to develop them in practice. A high and rising number of publications has appeared addressing the concept of “smart city,” but not many address its implementation. This paper aims at a conceptual understanding of the smart city by describing its various facets and using them to develop an Input-Output model helping policymakers and analysts make informed design choices. Using this model allows them to further their conceptual understanding of smart cities, envisage design choices they will face during planning and implementation, and help them to understand the impact of these choices. The model is illustrated by introducing the case of “Smart Dubai.” Overall, this paper provides enhanced understanding of smart city development processes. This can be used in decision-making processes.","design variables; implementation; input-output model; Smart city development; Smart Dubai","en","journal article","","","","","","","","","","","Information and Communication Technology","","",""
"uuid:794fdb41-f400-4029-99e4-b37aeaa13c4e","http://resolver.tudelft.nl/uuid:794fdb41-f400-4029-99e4-b37aeaa13c4e","Conversion strategies for dutch primary schools: Practice and refinement","Broekhuizen, A. (Dolf Broekhuizen Architecture Historian); Arkesteijn, M.H. (TU Delft Real Estate Management); de Jong, P. (TU Delft Design & Construction Management); Van Nieuwamerongen, Frido (Arconiko)","","2020","Handbooks on strategic real estate management are generally based on four strategies for functional adjustment of the building: Conversion, expansion, renovation and adaptive reuse. And on a strategic level, this classification in adjustment strategies does work for real estate in general. But when looking at Dutch primary schools as a specific type of real estate, reality can be and is more nuanced. Other accommodation strategies came to the fore in a study into the spatial adaptation of primary schools and children’s centres in the Netherlands. An analysis of 100 school buildings studied in the Atlas of School Building (published in Dutch as Scholenbouwatlas) revealed that nine main strategies were prevalent in practice. This refinement of the strategies fits (better) with integrated conversion actions of primary schools in which several aspects are solved together. In the following article these strategies are analysed and discussed in a theoretical context. The conclusion of the analyses is that the existing general models in the strategic handling of the building stock in the case of specific real estate of primary schools can be refined.","Adaptation; Children’s centre; Conversion strategies; Renovation; Schools; Strategy","en","journal article","","","","","","","","","","","Real Estate Management","","",""
"uuid:c2994618-fda8-44d5-8167-769b3b7a2bab","http://resolver.tudelft.nl/uuid:c2994618-fda8-44d5-8167-769b3b7a2bab","Breakage behavior of biomass pellets: An experimental and numerical study","Gilvari, H. (TU Delft Transport Engineering and Logistics); de Jong, W. (TU Delft Large Scale Energy Storage); Schott, D.L. (TU Delft Transport Engineering and Logistics)","","2020","The presence and generation of fines and dust in the bulk of biomass pellets have inflicted several problems in the supply chain during transportation and storage, and the breakage behavior of pellets has been scarcely studied so far. Fines and dust are the consequences of impact and abrasive forces through the whole supply chain; however, the breakage happens at the particle level. Therefore, to study the fines generation, first, the breakage behavior of individual pellets should be understood, and then, the behavior of the bulk materials in operational conditions can be investigated. This paper aims to investigate the breakage behavior of individual pellets under experimental compression tests and to introduce a calibrated numerical model using discrete element method (DEM) in order to pave the way for further studies on pellet breakage. For that purpose, seven different types of biomass pellets were studied experimentally, and then, a calibrated model was introduced via the Timoshenko–Ehrenfest beam theory using DEM. Results show that the model could reasonably predict the breakage behavior of pellets under uniaxial and diametrical compressions. The findings could help to develop a new design of the equipment for transportation and handling of biomass pellets with the aim to reduce the amount of generating fines and dust.","Biomass pellet; Breakage behavior; Compression tests; Discrete element method; Timoshenko–Ehrenfest beam theory","en","journal article","","","","","","","","","","","Transport Engineering and Logistics","","",""
"uuid:6b99600e-5bb9-44db-bd66-7d3a32d29231","http://resolver.tudelft.nl/uuid:6b99600e-5bb9-44db-bd66-7d3a32d29231","Erratum: Lamb Waves and Adaptive Beamforming for Aberration Correction in Medical Ultrasound Imaging: Lamb Waves and Adaptive Beamforming for Aberration Correction in Medical Ultrasound Imaging (IEEE Trans.Ultrason., Ferroelectr., Freq. Control, early access (2020) DOI: 10.1109/TUFFC.2020.3007345)","Mozaffarzadeh, M. (TU Delft ImPhys/Medical Imaging); Minonzio, C.G. (TU Delft ImPhys/Medical Imaging); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Hemm, Simone (University of Applied Sciences and Arts Northwestern Switzerland); Renaud, G.G.J. (TU Delft ImPhys/Medical Imaging); Daeichin, V. (TU Delft ImPhys/Medical Imaging)","","2020","In the above article [1], we mentioned that the superposition of the different symmetric (S) modes in the frequencywavenumber (f-k) domain results in a high-intensity region where its slope corresponds to the longitudinal wave speed in the slab. However, we have recently understood that this highintensity region belongs to the propagation of a wave called lateral wave or head wave [2]-[5]. It is generated if the longitudinal sound speed of the aberrator (i.e., the PVC slab) is larger than that of water and if the incident wavefront is curved. When the incidence angle at the interface between water and PVC is near the critical angle, the refracted wave in PVC reradiates a small part of its energy into the fluid (i.e., the head wave). As discussed in [4], if the thickness of the waveguide is larger than the wavelength, the first arriving signal is the head wave. This is also the case in our study [1] where the ultrasound wavelength of a compressional wave in PVC was close to 1 mm, and a PVC slab with a thickness of 8 mm was used. In this Erratum, numerical simulations (with SimSonic solver [5]) and experimental measurements (with the same PVC slab used in [1]) are conducted to investigate the propagation of the Lamb waves and head wave in detail, for the specific configuration studied in [1]. The pitch and element width of the P4-1 probe were used to assemble the numerical signals [see Fig. 1(a)]. If all the data simulated for the P4-1 probe is used, there indeed is a region with a slope [see Fig. 1(b)], but this has a low intensity, meaning that the head wave has a relatively low amplitude compared to the specular reflections. Once the head wave is isolated, the sound speed can be estimated with a 0.3% error from the f-k domain plot [see Fig. 1(c)]. No significant difference is observed between Fig. 1(b) and (d), in which the head wave is muted. Our experimental results show that if only the head wave (the first arriving signal) is used [see Fig. 2(b)], the slope of the linear fitting in the f-k domain also yields the longitudinal sound speed of the PVC with a 0.3% error. Of note, the signal processing (i.e., linear fitting in the f-k domain) used in our study [1] still works for the head wave and is correct provided that the aberrator is parallel to the probe [6]. Also, in [1, p. 6], it is mentioned that “the curved structure of the skull might lead to other types of modes, such as the torsional modes.” Here, we acknowledge that this sentence is not correct, as torsional modes only exist in cylindrical waveguides or rectangular bars. We would like to mention that Guillaume Renaud is added as a coauthor to acknowledge his contribution to the findings reported in this Erratum.","Head; Biomedical imaging; Acoustics; Ultrasonic imaging; Slabs; Probes; Frequency control","en","journal article","","","","","","Erratum met andere DOI dan de DOI van het originele artikel Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2021-08-02","","","ImPhys/Medical Imaging","","",""
"uuid:ee49615f-4786-43c7-ad06-edd18463c0e1","http://resolver.tudelft.nl/uuid:ee49615f-4786-43c7-ad06-edd18463c0e1","Opening of endothelial cell–cell contacts due to sonoporation","Beekers, D.I. (Erasmus MC); Vegter, Merel (Erasmus MC); Lattwein, Kirby R. (Erasmus MC); Mastik, Frits (Erasmus MC); Beurskens, Robert (Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Kooiman, Klazina (Erasmus MC)","","2020","Ultrasound insonification of microbubbles can locally increase vascular permeability to enhance drug delivery. To control and optimize the therapeutic potential, we need to better understand the underlying biological mechanisms of the drug delivery pathways. The aim of this in vitro study was to elucidate the microbubble-endothelial cell interaction using the Brandaris 128 ultra-high-speed camera (up to 25 Mfps) coupled to a custom-built Nikon confocal microscope, to visualize both microbubble oscillation and the cellular response. Sonoporation and opening of cell-cell contacts by single αVβ3-targeted microbubbles (n = 152) was monitored up to 4 min after ultrasound insonification (2 MHz, 100–400 kPa, 10 cycles). Sonoporation occurred when microbubble excursion amplitudes exceeded 0.7 μm. Quantification of the influx of the fluorescent model drug propidium iodide upon sonoporation showed that the size of the created pore increased for larger microbubble excursion amplitudes. Microbubble-mediated opening of cell-cell contacts occurred as a cellular response upon sonoporation and did not correlate with the microbubble excursion amplitude itself. The initial integrity of the cell-cell contacts affected the susceptibly to drug delivery, since cell-cell contacts opened more often when cells were only partially attached to their neighbors (48%) than when fully attached (14%). The drug delivery outcomes were independent of nonlinear microbubble behavior, microbubble location, and cell size. In conclusion, by studying the microbubble–cell interaction at nanosecond and nanometer resolution the relationship between drug delivery pathways and their underlying mechanisms was further unraveled. These novel insights will aid the development of safe and efficient microbubble-mediated drug delivery.","Cell-cell contact opening; Drug delivery; High-speed imaging; Microbubbles; Sonoporation; Ultrasound","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:1c5db92d-95c4-40e0-ba73-ab140f72c6cd","http://resolver.tudelft.nl/uuid:1c5db92d-95c4-40e0-ba73-ab140f72c6cd","High-Resolution Imaging of Intracellular Calcium Fluctuations Caused by Oscillating Microbubbles","Beekers, D.I. (Erasmus MC); Mastik, Frits (Erasmus MC); Beurskens, Robert (Erasmus MC); Tang, Phoei Ying (Erasmus MC); Vegter, Merel (Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Kooiman, Klazina (Erasmus MC)","","2020","Ultrasound insonification of microbubbles can locally enhance drug delivery, but the microbubble–cell interaction remains poorly understood. Because intracellular calcium (Cai 2+) is a key cellular regulator, unraveling the Cai 2+ fluctuations caused by an oscillating microbubble provides crucial insight into the underlying bio-effects. Therefore, we developed an optical imaging system at nanometer and nanosecond resolution that can resolve Cai 2+ fluctuations and microbubble oscillations. Using this system, we clearly distinguished three Cai 2+ uptake profiles upon sonoporation of endothelial cells, which strongly correlated with the microbubble oscillation amplitude, severity of sonoporation and opening of cell–cell contacts. We found a narrow operating range for viable drug delivery without lethal cell damage. Moreover, adjacent cells were affected by a calcium wave propagating at 15 μm/s. With the unique optical system, we unraveled the microbubble oscillation behavior required for drug delivery and Cai 2+ fluctuations, providing new insight into the microbubble–cell interaction to aid clinical translation.","Cell–cell contact opening; Confocal microscopy; Drug delivery; High-speed imaging; Intracellular calcium; Microbubbles; Sonoporation; Ultrasound","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:0ebf0cf4-14ea-4482-9831-9cfafdb36ce4","http://resolver.tudelft.nl/uuid:0ebf0cf4-14ea-4482-9831-9cfafdb36ce4","Influence of nickel precursors on the properties and performance of Ni impregnated zeolite 5A and 13X catalysts in CO2 methanation","Wei, L. (TU Delft Large Scale Energy Storage); Haije, W.G. (TU Delft Large Scale Energy Storage); Kumar, Narendra (Åbo Akademi University); Peltonen, Janne (University of Turku); Peurla, Markus (University of Turku); Grenman, L.O.H. (Åbo Akademi University); de Jong, W. (TU Delft Large Scale Energy Storage)","","2020","Zeolite 13X and 5A supported Ni catalysts were synthesized for CO2 methanation using the evaporation impregnation method. The influence of using different Ni precursors (nitrate, citrate, and acetate) as well as calcination temperatures on the catalyst properties and performance were investigated. XRD, SEM-EDX, TEM, STEM-EDX, N2 physisorption, H2-TPR, TPD-NH3 and TG/DTA were used for detailed characterization of the catalysts. The parent structure of the zeolites did not change during catalyst synthesis. Using nickel citrate and acetate resulted in smaller NiO particle size compared to nitrate. STEM-EDX results showed that all the Ni-precursor complexes entered more efficiently the 13X zeolite structure, which is mainly due to steric hindrance resulting from the smaller pore size of 5A. Methanation experiments revealed that the 13X catalysts synthesized using nickel citrate (5% Ni) displayed clearly higher activity, compared to the catalysts synthesized using nickel nitrate or nickel acetate. A 79% conversion at 320 °C was obtained with 100% selectivity towards CH4 and the catalyst showed excellent stability during 200 h testing. Overall, it can be concluded that the Ni precursor significantly influences the physico-chemical characteristics and catalytic properties of Ni 13X and Ni 5A zeolite catalysts in CO2 methanation: complex size and pore size matter.","13X zeolite; 5A zeolite; Catalytic performance; CO methanation catalyst; Material properties; Ni precursor salt anions","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:937423c1-acfc-4f01-b7d8-854787549bd1","http://resolver.tudelft.nl/uuid:937423c1-acfc-4f01-b7d8-854787549bd1","Imaging of inflammatory cellular protagonists in human atherosclerosis: a dual-isotope SPECT approach","Barrett, Hilary E. (Erasmus MC); Meester, Eric J. (Erasmus MC); van Gaalen, Kim (Erasmus MC); van der Heiden, Kim (Erasmus MC); Krenning, Boudewijn J. (Erasmus MC); Beekman, F.J. (TU Delft RST/Biomedical Imaging; MILabs B.V.; University Medical Center Utrecht); Verhagen, H. J. (Erasmus MC); de Jong, M. (Erasmus MC); Gijsen, F.J.H. (Erasmus MC)","","2020","Purpose: Atherosclerotic plaque development and progression signifies a complex inflammatory disease mediated by a multitude of proinflammatory leukocyte subsets. Using single photon emission computed tomography (SPECT) coupled with computed tomography (CT), this study tested a new dual-isotope acquisition protocol to assess each radiotracer’s capability to identify plaque phenotype and inflammation levels pertaining to leukocytes expressing leukocyte function-associated antigen-1 (LFA-1) and the leukocyte subset of proinflammatory macrophages expressing somatostatin receptor subtype-2 (SST2). Individual radiotracer uptake was quantified and the presence of corresponding immunohistological cell markers was assessed. Methods: Human symptomatic carotid plaque segments were obtained from endarterectomy. Segments were incubated in dual-isotope radiotracers [111In]In-DOTA-butylamino-NorBIRT ([111In]In-Danbirt) and [99mTc]Tc-[N0–1 4,Asp0,Tyr3]-octreotate ([99mTc]Tc-Demotate 2) before scanning with SPECT/CT. Plaque phenotype was classified as pathological intimal thickening, fibrous cap atheroma or fibrocalcific using histology sections based on distinct morphological characteristics. Plaque segments were subsequently immuno-stained with LFA-1 and SST2 and quantified in terms of positive area fraction and compared against the corresponding SPECT images. Results: Focal uptake of co-localising dual-radiotracers identified the heterogeneous distribution of inflamed regions in the plaques which co-localised with positive immuno-stained regions of LFA-1 and SST2. [111In]In-Danbirt and [99mTc]Tc-Demotate 2 uptake demonstrated a significant positive correlation (r = 0.651; p = 0.001). Fibrous cap atheroma plaque phenotype correlated with the highest [111In]In-Danbirt and [99mTc]Tc-Demotate 2 uptake compared with fibrocalcific plaques and pathological intimal thickening phenotypes, in line with the immunohistological analyses. Conclusion: A dual-isotope acquisition protocol permits the imaging of multiple leukocyte subsets and the pro-inflammatory macrophages simultaneously in atherosclerotic plaque tissue. [111In]In-Danbirt may have added value for assessing the total inflammation levels in atherosclerotic plaques in addition to classifying plaque phenotype.","Atherosclerosis; Carotid artery; Dual-isotope; Inflammation; Leukocyte; Macrophage; SPECT imaging","en","journal article","","","","","","","","","","","RST/Biomedical Imaging","","",""
"uuid:f4502f84-5f39-40c6-8118-625901ff6ae9","http://resolver.tudelft.nl/uuid:f4502f84-5f39-40c6-8118-625901ff6ae9","Biomass pyrolysis TGA assessment with an international round robin","Anca-Couce, Andrés (Graz University of Technology); Tsekos, C. (TU Delft Large Scale Energy Storage); Retschitzegger, Stefan (BEST – Bioenergy and Sustainable Technologies); Zimbardi, Francesco (ENEA - Italian National Agency for New Technologies, Energy and Sustainable Economic Development); Funke, Axel (Karlsruhe Institut für Technologie); Banks, Scott (Aston University); Kraia, Tzouliana (Centre for Research and Technology-Hellas); Marques, Paula (Unidade de Bioenergia); Scharler, Robert (Graz University of Technology; BEST – Bioenergy and Sustainable Technologies); de Jong, W. (TU Delft Large Scale Energy Storage); Kienzl, Norbert (BEST – Bioenergy and Sustainable Technologies)","","2020","The large variations found in literature for the activation energy values of main biomass compounds (cellulose, hemicellulose and lignin) in pyrolysis TGA raise concerns regarding the reliability of both the experimental and the modelling side of the performed works. In this work, an international round robin has been conducted by 7 partners who performed TGA pyrolysis experiments of pure cellulose and beech wood at several heating rates. Deviations of around 20 – 30 kJ/mol were obtained in the activation energies of cellulose, hemicellulose and conversions up to 0.9 with beech wood when considering all experiments. The following method was employed to derive reliable kinetics: to first ensure that pure cellulose pyrolysis experiments from literature can be accurately reproduced, and then to conduct experiments at different heating rates and evaluate them with isoconversional methods to detect experiments that are outliers and to validate the reliability of the derived kinetics and employed reaction models with a fitting routine. The deviations in the activation energy values for the cases that followed this method, after disregarding other cases, were of 10 kJ/mol or lower, except for lignin and very high conversions. This method is therefore proposed in order to improve the consistency of data acquisition and kinetic analysis of TGA for biomass pyrolysis in literature, reducing the reported variability.","Biomass; Fitting; Isoconversional; Pyrolysis; Round robin; TGA","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:e497ecb1-2145-4d5d-a67e-f19d8909ba31","http://resolver.tudelft.nl/uuid:e497ecb1-2145-4d5d-a67e-f19d8909ba31","High-pressure electrochemical reduction of CO2 to formic acid/formate: Effect of pH on the downstream separation process and economics","Ramdin, M. (TU Delft Engineering Thermodynamics); Morrison, A.R.T. (TU Delft Large Scale Energy Storage); de Groen, M. (Coval Energy); van Haperen, M.C.H. (Coval Energy); De Kler, Robert (Coval Energy); Irtem, Erdem (Universiteit Antwerpen); Laitinen, Antero T. (VTT Technical Research Center of Finland); van den Broeke, L.J.P. (TU Delft Engineering Thermodynamics); Breugelmans, Tom (Universiteit Antwerpen); Trusler, J. P.Martin (Imperial College London); de Jong, W. (TU Delft Large Scale Energy Storage); Vlugt, T.J.H. (TU Delft Engineering Thermodynamics)","","2019","We use a high-pressure semicontinuous batch electrochemical reactor with a tin-based cathode to demonstrate that it is possible to efficiently convert CO2 to formic acid (FA) in low-pH (i.e., pH < pKa) electrolyte solutions. The effects of CO2 pressure (up to 50 bar), bipolar membranes, and electrolyte (K2SO4) concentration on the current density (CD) and the Faraday efficiency (FE) of formic acid were investigated. The highest FE (?80%) of FA was achieved at a pressure of around 50 bar at a cell potential of 3.5 V and a CD of ?30 mA/cm2. To suppress the hydrogen evolution reaction (HER), the electrochemical reduction of CO2 in aqueous media is typically performed at alkaline conditions. The consequence of this is that products like formic acid, which has a pKa of 3.75, will almost completely dissociate into the formate form. The pH of the electrolyte solution has a strong influence not only on the electrochemical reduction process of CO2 but also on the downstream separation of (dilute) acid products like formic acid. The selection of separation processes depends on the dissociation state of the acids. A review of separation technologies for formic acid/formate removal from aqueous dilute streams is provided. By applying common separation heuristics, we have selected liquid-liquid extraction and electrodialysis for formic acid and formate separation, respectively. An economic evaluation of both separation processes shows that the formic acid route is more attractive than the formate one. These results urge for a better design of (1) CO2 electrocatalysts that can operate at low pH without affecting the selectivity of the desired products and (2) technologies for efficient separation of dilute products from (photo)electrochemical reactors.","","en","journal article","","","","","","","","","","","Engineering Thermodynamics","","",""
"uuid:f011b6a0-2109-44a6-95bd-c16d523643ae","http://resolver.tudelft.nl/uuid:f011b6a0-2109-44a6-95bd-c16d523643ae","4-D Echo-Particle Image Velocimetry in a Left Ventricular Phantom","Voorneveld, J.D. (TU Delft ChemE/Transport Phenomena; Erasmus MC); Saaid, H. (TU Delft ChemE/Transport Phenomena; Universiteit Gent); Schinkel, C.V. (TU Delft ChemE/O&O groep); Radeljic, Nikola (Oldelft Ultrasound); Lippe, Boris (Oldelft Ultrasound); Gijsen, F.J.H. (TU Delft ChemE/Transport Phenomena; Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Acoustical Wavefield Imaging; TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Claessens, Tom (Universiteit Gent); Vos, H.J. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Kenjeres, S. (TU Delft ChemE/Transport Phenomena); Bosch, Johan G. (Erasmus MC)","","2020","Left ventricular (LV) blood flow is an inherently complex time-varying 3-D phenomenon, where 2-D quantification often ignores the effect of out-of-plane motion. In this study, we describe high frame rate 4-D echocardiographic particle image velocimetry (echo-PIV) using a prototype matrix transesophageal transducer and a dynamic LV phantom for testing the accuracy of echo-PIV in the presence of complex flow patterns. Optical time-resolved tomographic PIV (tomo-PIV) was used as a reference standard for comparison. Echo-PIV and tomo-PIV agreed on the general profile of the LV flow patterns, but echo-PIV smoothed out the smaller flow structures. Echo-PIV also underestimated the flow rates at greater imaging depths, where the PIV kernel size and transducer point spread function were large relative to the velocity gradients. We demonstrate that 4-D echo-PIV could be performed in just four heart cycles, which would require only a short breath-hold, providing promising results. However, methods for resolving high velocity gradients in regions of poor spatial resolution are required before clinical translation.","4-D echo-PIV; 4-D ultrasound; Echo particle image velocimetry; High frame rate ultrasound; Left ventricle; Tomographic PIV; Ultrafast ultrasound; Ultrasound image velocimetry; Vector flow imaging; Volumetric flow","en","journal article","","","","","","","","","","","ChemE/Transport Phenomena","","",""
"uuid:f4f334a6-121a-4ac9-9d3b-8024bd8e0595","http://resolver.tudelft.nl/uuid:f4f334a6-121a-4ac9-9d3b-8024bd8e0595","PAH sampling and quantification from woody biomass fast pyrolysis in a pyroprobe reactor with a modified tar sampling system","Tsekos, C. (TU Delft Large Scale Energy Storage); Anastasakis, K. (TU Delft Energy Technology; Aarhus University); Schoenmakers, P.L.; de Jong, W. (TU Delft Large Scale Energy Storage; Rijksuniversiteit Groningen)","","2020","The present work focuses on the sampling procedure and quantification of the PAH yield from the fast pyrolysis of waste softwood. In particular, fast pyrolysis experiments were conducted using a CDS Pyroprobe 5200 at temperatures between 500 °C and 1000 °C, at a heating rate of 600 °C/s for a sample size of 30 mg. High performance liquid chromatography (HPLC) was used for the determination of the PAH compounds present in the liquid sample fraction, while a micro – GC was employed for the analysis of the main gaseous products (CO, CO2, CH4 and H2). An alternative tar sampling protocol was proposed, which employed the use of a cold trap (50 °C) and an isopropanol filled impinger bottle for the collection of the condensable products. The experiments were compared to heated foil reactor based pyrolysis tests within the same temperature range and heating rate, except for a slightly lower sample size (10 mg). The Pyroprobe and adapted sampling system proved to be more efficient regarding PAH capture and quantification compared to the heated foil reactor. Naphthalene, acenaphthylene and phenanthrene were the main PAH compounds detected. The PAH yields increased with pyrolysis temperature, up to values corresponding to roughly 0.2 wt% of the overall yield at 1000 °C. From the results it was derived that PAH evolution is mainly a product of secondary decomposition of primary tar, since the char yield stabilized for higher temperatures and the yields of CO, H2 and CH4 increased. Overall mass balance closure values were around 80 wt% on average. Char and gas yields were determined with high reproducibility, however gravimetric liquid analysis lacked due to the inability to gravimetrically measure the yield condensing in the impinger bottle. Future work is aimed on improving on this particular aspect. Overall, the alternative tar sampling system proposed was successful in the quantification of PAH from biomass fast pyrolysis experiments offering increased flexibility, accuracy and practicality of use.","Fast pyrolysis; Polycyclic aromatic hydrocarbons; Pyroprobe; Tar; Wood","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:b5642076-5913-425c-963c-c1c8c48b169e","http://resolver.tudelft.nl/uuid:b5642076-5913-425c-963c-c1c8c48b169e","Revealing charge-tunneling processes between a quantum dot and a superconducting island through gate sensing","van Veen, J. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); de Jong, D. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Han, L. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Prosko, C.G. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Krogstrup, P. (University of Copenhagen); Watson, J.D. (TU Delft QRD/Kouwenhoven Lab; Microsoft Quantum Lab Delft); Kouwenhoven, Leo P. (TU Delft QRD/Kouwenhoven Lab; TU Delft QN/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft; Microsoft Quantum Lab Delft); Pfaff, W. (TU Delft QRD/Kouwenhoven Lab; Microsoft Quantum Lab Delft)","","2019","We report direct detection of charge tunneling between a quantum dot and a superconducting island through radio-frequency gate sensing. We are able to resolve spin-dependent quasiparticle tunneling as well as two-particle tunneling involving Cooper pairs. The quantum dot can act as an RF-only sensor to characterize the superconductor addition spectrum, enabling us to access subgap states without transport. Our results provide guidance for future dispersive parity measurements of Majorana modes, which can be realized by detecting the parity-dependent tunneling between dots and islands.","","en","journal article","","","","","","","","","","","QRD/Kouwenhoven Lab","","",""
"uuid:69b30b25-f46f-4be8-bf59-ae95a68b68f2","http://resolver.tudelft.nl/uuid:69b30b25-f46f-4be8-bf59-ae95a68b68f2","Development of a stationary 3D photoacoustic imaging system using sparse single-element transducers: Phantom study","Kratkiewicz, Karl (Wayne State University); Manwar, Rayyan (Wayne State University); Zafar, Mohsin (Wayne State University); Ranjbaran, Seyed Mohsen (University of Isfahan); Mozaffarzadeh, M. (TU Delft ImPhys/Acoustical Wavefield Imaging); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Ji, Kailai (Nanjing Medical University); Avanaki, Kamran (Wayne State University; Barbara Ann Karmanos Cancer Institute)","","2019","Photoacoustic imaging (PAI) is an emerging label-free and non-invasive modality for imaging biological tissues. PAI has been implemented in different configurations, one of which is photoacoustic computed tomography (PACT) with a potential wide range of applications, including brain and breast imaging. Hemispherical Array PACT (HA-PACT) is a variation of PACT that has solved the limited detection-view problem. Here, we designed an HA-PACT system consisting of 50 single element transducers. For implementation, we initially performed a simulation study, with parameters close to those in practice, to determine the relationship between the number of transducers and the quality of the reconstructed image. We then used the greatest number of transducers possible on the hemisphere and imaged copper wire phantoms coated with a light absorbing material to evaluate the performance of the system. Several practical issues such as light illumination, arrangement of the transducers, and an image reconstruction algorithm have been comprehensively studied.","Hemisphere; Homogenous; Low-cost; PACT","en","journal article","","","","","","","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:e40ad465-1435-422f-a353-509b49d2799d","http://resolver.tudelft.nl/uuid:e40ad465-1435-422f-a353-509b49d2799d","Receive/transmit aperture selection for 3D ultrasound imaging with a 2D matrix transducer","Mozaffarzadeh, M. (TU Delft ImPhys/Medical Imaging); Soozande, M. (Erasmus MC); Fool, F. (TU Delft ImPhys/Medical Imaging); Pertijs, M.A.P. (TU Delft Electronic Instrumentation); Vos, H.J. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging); Bosch, Johan G. (Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC)","","2020","Recently, we realized a prototype matrix transducer consisting of 48 rows of 80 elements on top of a tiled set of Application Specific Integrated Circuits (ASICs) implementing a row-level control connecting one transmit/receive channel to an arbitrary subset of elements per row. A fully sampled array data acquisition is implemented by a column-by-column (CBC) imaging scheme (80 transmit-receive shots) which achieves 250 volumes/second (V/s) at a pulse repetition frequency of 20 kHz. However, for several clinical applications such as carotid pulse wave imaging (CPWI), a volume rate of 1000 per second is needed. This allows only 20 transmit-receive shots per 3D image. In this study, we propose a shifting aperture scheme and investigate the effects of receive/transmit aperture size and aperture shifting step in the elevation direction. The row-level circuit is used to interconnect elements of a receive aperture in the elevation (row) direction. An angular weighting method is used to suppress the grating lobes caused by the enlargement of the effective elevation pitch of the array, as a result of element interconnection in the elevation direction. The effective aperture size, level of grating lobes, and resolution/sidelobes are used to select suitable reception/transmission parameters. Based on our assessment, the proposed imaging sequence is a full transmission (all 80 elements excited at the same time), a receive aperture size of 5 and an aperture shifting step of 3. Numerical results obtained at depths of 10, 15, and 20 mm show that, compared to the fully sampled array, the 1000 V/s is achieved at the expense of, on average, about two times wider point spread function and 4 dB higher clutter level. The resulting grating lobes were at -27 dB. The proposed imaging sequence can be used for carotid pulse wave imaging to generate an informative 3D arterial stiffness map, for cardiovascular disease assessment.","2D matrix array; 3D ultrasound imaging; Carotid pulse wave imaging; Grating lobes reduc; High frame rate","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:c50fba8d-29d1-49aa-9a00-3bd40c8d232a","http://resolver.tudelft.nl/uuid:c50fba8d-29d1-49aa-9a00-3bd40c8d232a","Can bi-functional nickel modified 13X and 5A zeolite catalysts for CO2 methanation be improved by introducing ruthenium?","Wei, L. (TU Delft Large Scale Energy Storage); Kumar, Narendra (Åbo Akademi University); Haije, W.G. (TU Delft Large Scale Energy Storage); Peltonen, Janne (University of Turku); Peurla, Markus (University of Turku); Grenman, L.O.H. (Åbo Akademi University); de Jong, W. (TU Delft Large Scale Energy Storage)","","2020","Zeolites 13X and 5A were modified with nickel and/or ruthenium for CO2 methanation. The catalysts were prepared by evaporation impregnation and XRD, SEM-EDX, TEM, STEM-EDX, nitrogen physisorption, H2-TPR and NH3-TPD were used to characterize the physico-chemical properties of the catalysts. The physico-chemical characterization results show that the zeolites structure did not change after the Ni, Ru modification, however. Ni was able to enter the pores of 13X, in the other case, 5A, an egg shell type structure was formed. Methanation experiments were performed in a lab scale fixed bed reactor system, the results showed that the mono-metallic catalysts out-performed the bi-metallic ones with Ni being the more active. One of the factors influencing the performance of the bi-metallic catalysts was the difficulty to obtain good dispersion when both metals were used. Also the morphology of the catalyst significantly influenced the selectivity. The catalysts with lower weak acidity benefit for getting a higher activity. The single metal catalysts 2.5 %Ru13X and 5%Ni13X showed good catalytic stability with around 97 % CH4 selectivity at 360 °C, with no catalyst deactivation during the 200 h catalyst stability test.","13X and 5A zeolite catalysts; CO methanation; Ni and Ru","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2021-01-28","","","Large Scale Energy Storage","","",""
"uuid:611cacac-1ba8-4976-8bfe-0077c5c07c9f","http://resolver.tudelft.nl/uuid:611cacac-1ba8-4976-8bfe-0077c5c07c9f","Integrated transport management: Lessons from a Chinese city","Yang, W. (TU Delft Organisation & Governance); Veeneman, Wijnand (TU Delft Organisation & Governance); de Jong, W.M. (TU Delft Organisation & Governance; Erasmus Universiteit Rotterdam; Fudan University); Song, Y. (TU Delft Organisation & Governance)","","2020","Sustainable transport typically requires a broad spectrum of policy measures, with responsibilities shared by different authorities and with various public values competed with each other, such as commuting, health, spatial quality, and economic development. Designing and implementing integrated policy packages, with consideration for the interdependencies between measures and actors is a promising approach and thus an interesting research topic. A large part of the literature on transport policy looks at separate measures and their effects. These measures in reality always work in constellation with other measures and understanding their dependencies in a way to create synergies through packaging has been the topic of theoretical discussions. However, empirical research on policy packaging is sorely lacking. In this paper, we examine the implementation process of packaging of TM measures from the perspective of actors and their distinct roles and interactions. The data is collected by document analysis and interviews with officers in a Chinese city. Several major problems threatening the implementation of policy packaging are detected, including overlooking implementation at district-level, resource competition between measures, and the absence of integrative supervision. It provides a first answer to the discrepancy occurring in the promise of real-world crafting of well-integrated policies for sustainable mobility.","China; Infrastructure planning; Integrated transport policy; Multi-level governance; Policy packaging; Transport demand management","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:93536495-da03-4aef-9f41-1c517cff4532","http://resolver.tudelft.nl/uuid:93536495-da03-4aef-9f41-1c517cff4532","Towards developing a new model for inclusive cities in China: The case of Xiong'an New Area","Liu, Z. (TU Delft Integral Design & Management); de Jong, Martin (Fudan University; Erasmus Universiteit Rotterdam); Li, Fen (Shenzhen Institute of Building Research); Brand, A.D. (TU Delft Projects); Hertogh, M.J.C.M. (TU Delft Integral Design & Management); Liang, Dong (City University of Hongkong)","","2020","Along with unprecedented urbanization in the last few decades, cities have experienced rapid social and economic transformation in China. A major challenge facing urban authorities in the immediate future is how to plan and govern cities such that they can serve as inclusive systems where everyone is enabled and empowered to fully participate in and contribute to socioeconomic life. A first step towards realizing this is to conceptualize an integrated framework that allows analysts and decision-makers to delineate, evaluate, and guide the development of these cities towards inclusiveness. In this study, we conducted a conceptual analysis of urban inclusiveness and then proposed a multidimensional framework for the evaluation of inclusive development. This is followed by the presentation of the case of Xiong'an, for which inclusive development indicators (IDIs) were selected. By comparing the state before the establishment of Xiong'an with its current development progress, and analyzing the area's management structure and policy measures, the inclusive development challenges are identified. Subsequently, suggestions are given on how to direct Xiong'an toward higher levels of inclusiveness, including offering equal access to public services and employment opportunities, preserving environmental health and sustainable use of natural resources through waste recycling, and encouraging public participation in decision-making to bring higher levels of inclusion within reach.","Evaluation framework; Inclusive city; Inclusive urban development; Indicator system; Xiong'an New Area","en","journal article","","","","","","","","","","","Integral Design & Management","","",""
"uuid:01c2653c-54d0-4f3b-8790-09fe3c53ba0f","http://resolver.tudelft.nl/uuid:01c2653c-54d0-4f3b-8790-09fe3c53ba0f","A direct comparison of natural and acoustic-radiation-force-induced cardiac mechanical waves","Keijzer, Lana B.H. (Erasmus MC); Caenen, A.F.M. (Erasmus MC; Universiteit Gent; Katholieke Universiteit Leuven); Voorneveld, J.D. (Erasmus MC); Strachinaru, Mihai (Erasmus MC); Bowen, Daniel J. (Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Bosch, Johan G. (Erasmus MC); Vos, H.J. (TU Delft ImPhys/Medical Imaging; Erasmus MC)","","2020","Natural and active shear wave elastography (SWE) are potential ultrasound-based techniques to non-invasively assess myocardial stiffness, which could improve current diagnosis of heart failure. This study aims to bridge the knowledge gap between both techniques and discuss their respective impacts on cardiac stiffness evaluation. We recorded the mechanical waves occurring after aortic and mitral valve closure (AVC, MVC) and those induced by acoustic radiation force throughout the cardiac cycle in four pigs after sternotomy. Natural SWE showed a higher feasibility than active SWE, which is an advantage for clinical application. Median propagation speeds of 2.5–4.0 m/s and 1.6–4.0 m/s were obtained after AVC and MVC, whereas ARF-based median speeds of 0.9–1.2 m/s and 2.1–3.8 m/s were reported for diastole and systole, respectively. The different wave characteristics in both methods, such as the frequency content, complicate the direct comparison of waves. Nevertheless, a good match was found in propagation speeds between natural and active SWE at the moment of valve closure, and the natural waves showed higher propagation speeds than in diastole. Furthermore, the results demonstrated that the natural waves occur in between diastole and systole identified with active SWE, and thus represent a myocardial stiffness in between relaxation and contraction.","","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:ff206324-5972-41ea-ae5b-ed46c84d930a","http://resolver.tudelft.nl/uuid:ff206324-5972-41ea-ae5b-ed46c84d930a","It was twenty years ago today: Revisiting time-of-day choice in the Netherlands","de Jong, Gerard (Significance; University of Leeds); Kouwenhoven, M.L.A. (TU Delft Transport and Logistics; Significance); Daly, Andrew (University of Leeds); Thoen, S. (TU Delft Civil Engineering & Geosciences; Significance); de Gier, Matthijs (Kantar Public); Hofman, Frank (Ministry of Infrastructure and the Environment)","","2020","Time-of-day (TOD) choice can be considered as a fifth stage in the modelling of transport behaviour, additional to the conventional four stages. Twenty years ago in The Netherlands, a stated preference (SP) study was designed for investigating the choice of time-of-day (departure time) and transport mode. A nested logit time period and mode choice model, largely based on this SP data set, was included as one of the components of The Netherlands national transport model (LMS). A new TOD SP survey has now been developed to obtain up-to-date information for the next re-estimation round of the LMS. The fieldwork was carried out in in 2019, followed by the re-estimation of the nested logit model of period and mode choice on the new SP data. The context for the SP is that of a tour (round trip) carried out by the respondent as car driver or by train, also distinguishing by travel purpose (commuting, business, education and other). This means that we are asking questions both about the outward leg of the tour and the inward leg. Both car drivers and train users are asked to participate in two SP experiments on TOD and mode choice: the first focussing on the trade-off between congestion or crowding and the departure/arrival times; the second also with differentiation in costs between peak and off-peak. Our tentative conclusion is that TOD choice seems to have become (relatively to mode choice) more flexible in the past two decades, in line with the trends towards more flexibility in scheduling activities over the day and a 24 hours economy. Moreover, we now estimate nest coefficients for both car drivers and train users (until now the assumption that had to be made in the LMS was that the nest coefficients for train followed those for car).","Mode choice; National transport model; Stated preference survey; Time-of-day choice","en","journal article","","","","","","","","","Civil Engineering & Geosciences","","Transport and Logistics","","",""
"uuid:7648ddcd-6b09-4c35-a547-7d07dc4c569a","http://resolver.tudelft.nl/uuid:7648ddcd-6b09-4c35-a547-7d07dc4c569a","Genomic analysis of Caldalkalibacillus thermarum TA2.A1 reveals aerobic alkaliphilic metabolism and evolutionary hallmarks linking alkaliphilic bacteria and plant life","de Jong, S.I. (TU Delft BT/Environmental Biotechnology); van den Broek, M.A. (TU Delft BT/Industriele Microbiologie); Merkel, Alexander Y. (Russian Academy of Sciences); de la Torre Cortes, Pilar (Kavli institute of nanoscience Delft); Kalamorz, Falk (The New Zealand Institute for Plant and Food Research, Lincoln); Cook, Gregory M. (University of Otago); van Loosdrecht, Mark C.M. (TU Delft BT/Environmental Biotechnology); McMillan, D.G.G. (TU Delft BT/Biocatalysis)","","2020","The aerobic thermoalkaliphile Caldalkalibacillus thermarum strain TA2.A1 is a member of a separate order of alkaliphilic bacteria closely related to the Bacillales order. Efforts to relate the genomic information of this evolutionary ancient organism to environmental adaptation have been thwarted by the inability to construct a complete genome. The existing draft genome is highly fragmented due to repetitive regions, and gaps between and over repetitive regions were unbridgeable. To address this, Oxford Nanopore Technology’s MinION allowed us to span these repeats through long reads, with over 6000-fold coverage. This resulted in a single 3.34 Mb circular chromosome. The profile of transporters and central metabolism gives insight into why the organism prefers glutamate over sucrose as carbon source. We propose that the deamination of glutamate allows alkalization of the immediate environment, an excellent example of how an extremophile modulates environmental conditions to suit its own requirements. Curiously, plant-like hallmark electron transfer enzymes and transporters are found throughout the genome, such as a cytochrome b6c1 complex and a CO2-concentrating transporter. In addition, multiple self-splicing group II intron-encoded proteins closely aligning to those of a telomerase reverse transcriptase in Arabidopsis thaliana were revealed. Collectively, these features suggest an evolutionary relationship to plant life.","Alkaliphiles; Evolution; Genome; Phylogeny","en","journal article","","","","","","","","","","","BT/Environmental Biotechnology","","",""
"uuid:f0c94579-039c-4879-af6c-c6afb1578e55","http://resolver.tudelft.nl/uuid:f0c94579-039c-4879-af6c-c6afb1578e55","The 2021 flood event in the Dutch Meuse and tributaries from a hydraulic and morphological perspective","Strijker, B. (TU Delft Hydraulic Structures and Flood Risk; HKV); Asselman, Nathalie (Deltares); de Jong, Jurjen (Deltares; Sweco); Barneveld, Hermjan (Wageningen University & Research; HKV)","","2023","In July of 2021, large areas in the catchment of the Meuse River in Belgium, the Netherlands and Germany were affected by extreme rainfall and floods. This paper presents the hydraulic and morphological data that were collected during and after the flood. The data were analysed to understand the hydraulic and morphological functioning of the Meuse River in the Netherlands during the flood event. The data showed that measured peak discharges in the upstream part of the Meuse and regional tributaries were the highest ever recorded. However, as the flood had a very short duration, peak attenuation played an important role, resulting in discharges and water levels in downstream reaches that were lower than during previous floods. Furthermore, the implementation of river widening and floodplain lowering measures as part of the Meuse Works programme contributed to a reduction in peak water levels along the Meuse. The analysis also showed that flood forecasts in the upstream part of the Meuse in the Netherlands depended heavily on rainfall forecasts and rainfall-runoff modelling and underestimated the peak water levels up to 36 hours before the flood actually peaked. Further downstream, the lead time increases and forecasts are based on discharge levels that are measured in upstream parts of the catchments. This results in more accurate estimates. The floods have also resulted in unprecedented morphological changes. The armour layer in the riverbed of the ‘Common Meuse’, consisting of very coarse gravel, was mobilised and layers of fine sand quickly eroded. This resulted in multiple scour holes with depths of 3 to 15m, especially in a reach which was hardly or not at all widened in the room for the river programme called Meuse Works. In this reach, the flow velocities were high and even higher than prior to the Meuse Works.","floods July 2021; fact-finding; hydraulics; peak attenuation; morphodynamics","en","journal article","","","","","","","","","","","Hydraulic Structures and Flood Risk","","",""
"uuid:268a3b5b-fc9b-418f-948d-16530e661d33","http://resolver.tudelft.nl/uuid:268a3b5b-fc9b-418f-948d-16530e661d33","A Pitch-Matched High-Frame-Rate Ultrasound Imaging ASIC for Catheter-Based 3-D Probes","Hopf, Y.M. (TU Delft Electronic Instrumentation); Simoes dos Santos, D. (TU Delft ImPhys/Medical Imaging; TU Delft ImPhys/Verweij group); Ossenkoppele, Boudewine W. (Student TU Delft); Noothout, E.C. (TU Delft ImPhys/Verweij group); Chang, Z.Y. (TU Delft Electronic Instrumentation); Chen, Chao (Student TU Delft); Vos, H.J. (TU Delft ImPhys/Verweij group; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; TU Delft ImPhys/Verweij group; Erasmus MC); de Jong, N. (TU Delft ImPhys/De Jong group; Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation)","","2024","This article presents an application-specific integrated circuit (ASIC) for catheter-based 3-D ultrasound imaging probes. The pitch-matched design implements a comprehensive architecture with high-voltage (HV) transmitters, analog front ends, hybrid beamforming analog-To-digital converters (ADCs), and data transmission to the imaging system. To reduce the number of cables in the catheter while maintaining a small footprint per element, transmission (TX) beamforming is realized on the chip with a combination of a shift register (SR) and a row/column (R/C) approach. To explore an additional cable-count reduction in the receiver part of the design, a channel with a combination of time-division multiplexing (TDM), subarray beamforming, and multi-level pulse amplitude modulation (PAM) data transmission is also included. This achieves an 18-fold cable-count reduction and minimizes the power consumption in the catheter by a load modulation (LM) cable driver. It is further explored how common-mode interference can limit beamforming gain and a strategy to reduce its impact with local regulators is discussed. The chip was fabricated in TSMC 0.18-m HV BCD technology and a 2-D PZT transducer matrix of 16 × 18 elements with a pitch of 160 m and a center frequency of 6 MHz was manufactured on the chip. The system can generate all required TX patterns at up to 30 V, provides quick settling after the TX phase, and has an reception (RX) power consumption of only 1.12 mW/element. The functionality and operation of up to 1000 volumes/s have been demonstrated in electrical and acoustic imaging experiments.","3-D ultrasound; analog front end (AFE); common-mode interference suppression; high frame rate; intracardiac echocardiography (ICE); load-modulation datalink; transmit beamformer; transmit/receive (T/R) switching; ultrasound application-specific integrated circuit (ASIC)","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2024-07-30","","","Electronic Instrumentation","","",""
"uuid:dd034c4d-07bf-4b29-b382-33cdae30e0f6","http://resolver.tudelft.nl/uuid:dd034c4d-07bf-4b29-b382-33cdae30e0f6","Multiplexed Cas9 targeting reveals genomic location effects and gRNA-based staggered breaks influencing mutation efficiency","Gisler, Santiago (Netherlands Cancer Institute); P. Gonçalves, Joana (TU Delft Pattern Recognition and Bioinformatics; Netherlands Cancer Institute); Akhtar, Waseem (Netherlands Cancer Institute); de Jong, Johann (Netherlands Cancer Institute; UCB Biosciences GmbH); Pindyurin, Alexey V. (Russian Academy of Sciences; Netherlands Cancer Institute); Wessels, L.F.A. (TU Delft Pattern Recognition and Bioinformatics; Netherlands Cancer Institute); van Lohuizen, Maarten (Netherlands Cancer Institute)","","2019","Understanding the impact of guide RNA (gRNA) and genomic locus on CRISPR-Cas9 activity is crucial to design effective gene editing assays. However, it is challenging to profile Cas9 activity in the endogenous cellular environment. Here we leverage our TRIP technology to integrate ~ 1k barcoded reporter genes in the genomes of mouse embryonic stem cells. We target the integrated reporters (IRs) using RNA-guided Cas9 and characterize induced mutations by sequencing. We report that gRNA-sequence and IR locus explain most variation in mutation efficiency. Predominant insertions of a gRNA-specific nucleotide are consistent with template-dependent repair of staggered DNA ends with 1-bp 5′ overhangs. We confirm that such staggered ends are induced by Cas9 in mouse pre-B cells. To explain observed insertions, we propose a model generating primarily blunt and occasionally staggered DNA ends. Mutation patterns indicate that gRNA-sequence controls the fraction of staggered ends, which could be used to optimize Cas9-based insertion efficiency.","","en","journal article","","","","","","","","","","","Pattern Recognition and Bioinformatics","","",""
"uuid:baeef8f1-3649-450f-9190-863ebf4e72c3","http://resolver.tudelft.nl/uuid:baeef8f1-3649-450f-9190-863ebf4e72c3","Magnetic field compatible circuit quantum electrodynamics with graphene Josephson junctions","Kroll, J. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Uilhoorn, W. (TU Delft Applied Sciences; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); van der Enden, K.L. (TU Delft Applied Sciences; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); de Jong, D. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Watanabe, K. (National Institute for Materials Science); Taniguchi, T. (National Institute for Materials Science); Goswami, S. (TU Delft QRD/Goswami Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Cassidy, M.C. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Kouwenhoven, Leo P. (TU Delft QRD/Kouwenhoven Lab)","","2018","Circuit quantum electrodynamics has proven to be a powerful tool to probe mesoscopic effects in hybrid systems and is used in several quantum computing (QC) proposals that require a transmon qubit able to operate in strong magnetic fields. To address this we integrate monolayer graphene Josephson junctions into microwave frequency superconducting circuits to create graphene based transmons. Using dispersive microwave spectroscopy we resolve graphene's characteristic band dispersion and observe coherent electronic interference effects confirming the ballistic nature of our graphene Josephson junctions. We show that the monoatomic thickness of graphene renders the device insensitive to an applied magnetic field, allowing us to perform energy level spectroscopy of the circuit in a parallel magnetic field of 1 T, an order of magnitude higher than previous studies. These results establish graphene based superconducting circuits as a promising platform for QC and the study of mesoscopic quantum effects that appear in strong magnetic fields.","","en","journal article","","","","","","","","","Applied Sciences","","QRD/Kouwenhoven Lab","","",""
"uuid:e9ff48d3-c779-4257-b881-85d09bd41929","http://resolver.tudelft.nl/uuid:e9ff48d3-c779-4257-b881-85d09bd41929","Lateral adsorbate interactions inhibit HCOO− while promoting CO selectivity for CO2 electrocatalysis on silver","Bohra, D. (TU Delft ChemE/Materials for Energy Conversion and Storage); Ledezma Yanez, I.D. (TU Delft Large Scale Energy Storage); Li, G. (TU Delft ChemE/Catalysis Engineering); de Jong, W. (TU Delft Large Scale Energy Storage); Pidko, E.A. (TU Delft ChemE/Inorganic Systems Engineering); Smith, W.A. (TU Delft ChemE/Materials for Energy Conversion and Storage)","","2019","Ag is a promising catalyst for the production of carbon monoxide (CO) via the electrochemical reduction of carbon dioxide (CO2ER). Herein, we study the role of the formate (HCOO−) intermediate *OCHO, aiming to resolve the discrepancy between the theoretical understanding and experimental performance of Ag. We show that the first coupled proton-electron transfer (CPET) step in the CO pathway competes with the Volmer step for formation of *H, whereas this Volmer step is a prerequisite for the formation of *OCHO. We show that *OCHO should form readily on the Ag surface owing to solvation and favorable binding strength. In situ surface-enhanced Raman spectroscopy (SERS) experiments give preliminary evidence of the presence of O-bound bidentate species on polycrystalline Ag during CO2ER which we attribute to *OCHO. Lateral adsorbate interactions in the presence of *OCHO have a significant influence on the surface coverage of *H, resulting in the inhibition of HCOO− and H2 production and a higher selectivity towards CO.","adsorbate-adsorbate interactions; DFT; electrocatalysis; in situ studies; Raman spectroscopy","en","journal article","","","","","","","","","","","ChemE/Materials for Energy Conversion and Storage","","",""
"uuid:993d9b3e-8f85-44b0-898e-3a9ae0335f26","http://resolver.tudelft.nl/uuid:993d9b3e-8f85-44b0-898e-3a9ae0335f26","The geopolitical impact of the shale revolution: Exploring consequences on energy prices and rentier states","Auping, Willem L. (TU Delft Policy Analysis); Pruyt, E. (TU Delft Policy Analysis); de Jong, Sijbren (The Hague Centre for Strategic Studies); Kwakkel, J.H. (TU Delft Policy Analysis)","","2016","While the shale revolution was largely a US’ affair, it affects the global energy system. In this paper, we look at the effects of this spectacular increase in natural gas, and oil, extraction capacity can have on the mix of primary energy sources, on energy prices, and through that on internal political stability of rentier states. We use two exploratory simulation models to investigate the consequences of the combination of both complexity and uncertainty in relation to the global energy system and state stability. Our simulations show that shale developments could be seen as part of a long term hog-cycle, with a short term drop in oil prices if unconventional supply substitutes demand for oil. These lower oil prices may lead to instability in rentier states neighbouring the EU, especially when dependence on oil and gas income is high, youth bulges are present, or buffers like sovereign wealth funds are too limited to bridge the negative economic effects of temporary low oil prices.","Energy mix; Energy prices; Exploratory modelling; Shale revolution; State stability; System Dynamics","en","journal article","","","","","","Accepted author manuscript","","","","","Policy Analysis","","",""
"uuid:0c28e102-895c-452e-a36b-2977e7511d96","http://resolver.tudelft.nl/uuid:0c28e102-895c-452e-a36b-2977e7511d96","Rapid Detection of Coherent Tunneling in an InAs Nanowire Quantum Dot through Dispersive Gate Sensing","de Jong, D. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre); van Veen, J. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre); Binci, L. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre); Singh, A. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre); Krogstrup, P. (University of Copenhagen); Kouwenhoven, Leo P. (TU Delft QRD/Kouwenhoven Lab; TU Delft QN/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Microsoft Quantum Lab Delft); Pfaff, W. (TU Delft QRD/Kouwenhoven Lab; Microsoft Quantum Lab Delft); Watson, J.D. (TU Delft QRD/Kouwenhoven Lab; Microsoft Quantum Lab Delft)","","2019","Dispersive sensing is a powerful technique that enables scalable and high-fidelity readout of solid-state quantum bits. In particular, gate-based dispersive sensing has been proposed as the readout mechanism for future topological qubits, which can be measured by single electrons tunneling through zero-energy modes. The development of such a readout requires resolving the coherent charge tunneling amplitude from a quantum dot in a Majorana-zero-mode host system faithfully on short time scales. Here, we demonstrate rapid single-shot detection of a coherent single-electron tunneling amplitude between InAs nanowire quantum dots. We realize a sensitive dispersive detection circuit by connecting a sub-GHz, lumped-element microwave resonator to a high-lever arm gate on one of the dots. The resulting large dot-resonator coupling leads to an observed dispersive shift that is of the order of the resonator linewidth at charge degeneracy. This shift enables us to differentiate between Coulomb blockade and resonance - corresponding to the scenarios expected for qubit-state readout - with a signal-to-noise ratio exceeding 2 for an integration time of 1μs. Our result paves the way for single-shot measurements of fermion parity on microsecond time scales in topological qubits.","","en","journal article","","","","","","","","","","","QRD/Kouwenhoven Lab","","",""
"uuid:1cd4f288-0972-448b-8fcf-f33a72b971fa","http://resolver.tudelft.nl/uuid:1cd4f288-0972-448b-8fcf-f33a72b971fa","Cultivating the next generation designers: Group work in urban and regional design education","Qu, L. (TU Delft Spatial Planning and Strategy); Chen, Y. (TU Delft Urban Development Management); Rooij, R.M. (TU Delft Spatial Planning and Strategy); de Jong, P. (TU Delft Design & Construction Management)","","2019","This article will contribute to filling the knowledge gap about learning from group methods in (urban and regional) design education, with action research results based on real teaching activities in TU Delft, Faculty of Architecture and the Built Environment (A&BE), conducted and coordinated by the authors. Constructive alignment of the teaching triangle and feedbacks from students are used to assess the necessity and effectiveness of group work in achieving learning objectives in the chosen courses. The conclusions of the article focus on pros and cons of group-working in urban and regional design education, with highlighted common challenges in implementing group work, such as proper distribution of workload among group members and assessing individual performance, as well as specific challenges of certain courses, such as stimulating ‘out of the box thinking’ in the setting of ‘role play’ and supervising interdisciplinary groups in the setting of research and design studio.","Collaborative learning; Constructive alignment; Design studio; Group work","en","journal article","","","","","","","","","","","Spatial Planning and Strategy","","",""
"uuid:383fe7ca-77cc-4bc1-af68-4ca73a1177ee","http://resolver.tudelft.nl/uuid:383fe7ca-77cc-4bc1-af68-4ca73a1177ee","Collection of amino acids and DNA from fingerprints using hydrogels","van Helmond, W. (Netherlands Forensic Institute - NFI; Universiteit van Amsterdam); O'Brien, V. (TU Delft ChemE/Advanced Soft Matter); de Jong, R. (Digital Technology and Biometrics; Netherlands Forensic Institute - NFI); van Esch, J.H. (TU Delft ChemE/Advanced Soft Matter); Oldenhof, S. (TU Delft ChemE/Advanced Soft Matter; Netherlands Forensic Institute - NFI); de Puit, M. (TU Delft OLD ChemE/Organic Materials and Interfaces; Netherlands Forensic Institute - NFI)","","2018","The amino acid profile obtained from a fingerprint may provide valuable information on its donor. For forensic scientists, recovering evidence relating to the amino acid profile of a suspect can potentially be valuable for identification and exclusion purposes. Herein we detail the use of cross-linkable solutions of dextran-methacrylate to form hydrogels capable of collecting amino acids from surfaces followed by extraction and quantification with UPLC-MS. This method allows for the amino acid profile analysis of fingerprints while allowing for their increased visualisation at a later stage using the standard method of cyanoacrylation. We will demonstrate this method to also be capable of collecting DNA from fingerprints with a 20-60% yield in comparison to using a conventional cotton swab.","","en","journal article","","","","","","","","","","","ChemE/Advanced Soft Matter","","",""
"uuid:48e11e15-caf8-48d5-b3b0-30a46fca5699","http://resolver.tudelft.nl/uuid:48e11e15-caf8-48d5-b3b0-30a46fca5699","Experimental and numerical investigation of contact heat transfer between a rotating heat pipe and a steel strip","Çelik, M. (TU Delft Energy Technology); Devendran, Kathikeyan (Student TU Delft); Paulussen, Geert (Tata Steel); Pronk, Pepijn (Tata Steel); Frinking, Ferry (Tata Steel); de Jong, W. (TU Delft Large Scale Energy Storage); Boersma, B.J. (TU Delft Process and Energy; TU Delft Energy Technology)","","2018","A new concept for energy efficient annealing of steel strip comprises of multiple rotating heat pipes. Each heat pipe extracts heat from the cooling strip which is reused to increase the temperature of the heating strip. In this context, the heat transfer between the steel strip and the rotating heat pipe is investigated. When the strip is transported over the heat pipe, gas entrains in the gap. The gas compresses into a uniform gas layer. The contact heat transfer deteriorates due to this phenomenon. A numerical model to quantify the heat transfer between the surfaces is developed. Since there is no direct way to quantify the heat transfer between two moving surfaces, the problem is divided into a gas entrainment and a heat transfer part. The model is validated with experiments executed on a rotating heat pipe test rig. The validation was made varying the strip thickness, specific tension and strip velocity. The results show a uniform gas layer forming within the first 1° of the 180° wrap angle in all cases. The heat transfer is dominated by gas conduction. Results for the uniform gas layer region yield heat transfer coefficients in the range between 4000 and 20,000 W/m2·K.","Contact heat transfer; Experimental validation; Gas entrainment; Numerical model; Rotating heat pipe","en","journal article","","","","","","","","","","Process and Energy","Energy Technology","","",""
"uuid:9304e5c5-0d01-4b43-8704-fef57bb9700f","http://resolver.tudelft.nl/uuid:9304e5c5-0d01-4b43-8704-fef57bb9700f","City branding in China's Northeastern region: How do cities reposition themselves when facing industrial decline and ecological modernization?","Han, Meiling (Harbin Institute of Technology; Erasmus Universiteit Rotterdam); de Jong, W.M. (TU Delft Organisation & Governance; Fudan University; Erasmus Universiteit Rotterdam); Cui, Zhuqing (Harbin Institute of Technology); Xu, L. (Harbin Institute of Technology); Lu, H. (TU Delft Organisation & Governance); Sun, Baiqing (Harbin Institute of Technology)","","2018","The past decade has seen a surge in the use of city branding, which is used to attract specific target groups of investors, high-tech green firms and talented workforce and reflects a desired shift from old, polluting manufacturing industries to new, clean service industries. Previous studies in the Chinese mega-city regions Pearl River Delta, Yangtze River Delta and Jing-Jin-Ji (region around Beijing and Tianjin) have shown that branding practices of primarily service and innovation oriented cities are largely in line with existing industrial profiles while those which are predominantly manufacturing oriented wish to present themselves as more service and innovation driven. In this contribution, city branding practices are studied in China's three Northeastern provinces Heilongjiang, Jilin and Liaoning which face structural decline because of the presence of many outdated resource-based and heavy industries. The gap between existing profile and branding choices appears not systematic as in China's leading economic regions. Northeastern cities focus more on combining primary, secondary and tertiary industrial patterns than on displacing manufacturing with services. The tertiary sector in these provinces is more administrative and public sector oriented and generates lower value added; it is therefore not significantly more attractive than the primary and secondary ones.","City brand identity; City branding; City label; Developmental pathways; Ecologicalmodernization; North East China","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:b52cdb35-e35d-4a99-b93f-313e3e6048af","http://resolver.tudelft.nl/uuid:b52cdb35-e35d-4a99-b93f-313e3e6048af","Manufacture of highly loaded silica-supported cobalt Fischer-Tropsch catalysts from a metal organic framework","Sun, X. (TU Delft ChemE/Catalysis Engineering); Olivos Suarez, A.I. (TU Delft ChemE/Catalysis Engineering); Meijerink, Mark (Universiteit Utrecht); Van Deelen, Tom (Universiteit Utrecht); Ould-Chikh, Samy (King Abdullah University of Science and Technology); Zečević, Jovana (Universiteit Utrecht); de Jong, K.M. (TU Delft Information Management); Kapteijn, F. (TU Delft ChemE/Catalysis Engineering); Gascon, Jorge (TU Delft ChemE/Catalysis Engineering; King Abdullah University of Science and Technology)","","2017","The development of synthetic protocols for the preparation of highly loaded metal nanoparticle-supported catalysts has received a great deal of attention over the last few decades. Independently controlling metal loading, nanoparticle size, distribution, and accessibility has proven challenging because of the clear interdependence between these crucial performance parameters. Here we present a stepwise methodology that, making use of a cobalt-containing metal organic framework as hard template (ZIF-67), allows addressing this long-standing challenge. Condensation of silica in the Co-metal organic framework pore space followed by pyrolysis and subsequent calcination of these composites renders highly loaded cobalt nanocomposites (~ 50 wt.% Co), with cobalt oxide reducibility in the order of 80% and a good particle dispersion, that exhibit high activity, C5 + selectivity and stability in Fischer-Tropsch synthesis.","","en","journal article","","","","","","","","","","","ChemE/Catalysis Engineering","","",""
"uuid:f69daf1e-73af-4434-9511-4bddf1b4e48d","http://resolver.tudelft.nl/uuid:f69daf1e-73af-4434-9511-4bddf1b4e48d","SPIO labeling of endothelial cells using ultrasound and targeted microbubbles at diagnostic pressures","Skachkov, Ilya (Erasmus MC); Luan, Ying (Erasmus MC); Van Tiel, Sandra T. (Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Bernsen, Monique R. (Erasmus MC); Kooiman, Klazina (Erasmus MC)","","2018","In vivo cell tracking of therapeutic, tumor, and endothelial cells is an emerging field and a promising technique for imaging cardiovascular disease and cancer development. Site-specific labeling of endothelial cells with the MRI contrast agent superparamagnetic iron oxide (SPIO) in the absence of toxic agents is challenging. Therefore, the aim of this in vitro study was to find optimal parameters for efficient and safe SPIO-labeling of endothelial cells using ultrasound-activated CD31-targeted microbubbles for future MRI tracking. Ultrasound at a frequency of 1 MHz (10,000 cycles, repetition rate of 20 Hz) was used for varying applied peak negative pressures (10–160 kPa, i.e. low mechanical index (MI) of 0.01–0.16), treatment durations (0–30 s), time of SPIO addition (-5 min– 15 min with respect to the start of the ultrasound), and incubation time after SPIO addition (5 min– 3 h). Iron specific Prussian Blue staining in combination with calcein-AM based cell viability assays were applied to define the most efficient and safe conditions for SPIO-labeling. Optimal SPIO labeling was observed when the ultrasound parameters were 40 kPa peak negative pressure (MI 0.04), applied for 30 s just before SPIO addition (0 min). Compared to the control, this resulted in an approximate 12 times increase of SPIO uptake in endothelial cells in vitro with 85% cell viability. Therefore, ultrasound-activated targeted ultrasound contrast agents show great potential for effective and safe labeling of endothelial cells with SPIO.","","en","journal article","","","","","","","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:0c1da71b-2c05-4949-839d-809337f7e376","http://resolver.tudelft.nl/uuid:0c1da71b-2c05-4949-839d-809337f7e376","Multiscale modeling of the effect of sub-ply voids on the failure of composite materials","Turteltaub, S.R. (TU Delft Novel Aerospace Materials; TU Delft Aerospace Structures & Computational Mechanics); de Jong, Gijs (Student TU Delft)","","2019","A multiscale fracture model is developed to study the influence of defects appearing at a microscale in a fiber-reinforced composite laminate. The model establishes a link between the geometrical characteristics of sub-ply imperfections that may be created during manufacturing and the overall fracture strength and fracture energy of the composite. In particular, a recently-developed multiscale theory is expanded to account for microvoids inside the matrix and gaps between closely-spaced fibers that prevent filling. These defects are explicitly incorporated in finite element simulations to study their influence on the onset and propagation of cracks at the sub-ply level. To connect these microcracks to the effective fracture behavior at a ply-level, a computational homogenization technique is applied to extract the energetically-equivalent macroscopic fracture properties. Through a parametric analysis of configurations, the influence of the void content (porosity), void type and void shape on the effective fracture strength and the effective fracture energy of a composite are quantified. Results show that the porosity is the main parameter influencing fracture properties while the shape of the defects and their type (matrix or interfiber) only play a secondary role. Furthermore, the influence of voids on the fracture properties appears to be strongly dependent on the loading conditions. In particular, for the range of porosity analyzed (up to 8%), the influence of voids in mode I on the transverse fracture strength is not significant but the transverse fracture energy decreases approximately linearly down to about 50% of its original value. In contrast, in mode II, the transverse fracture strength is significantly affected with increasing porosity. Furthermore, the transverse fracture energy depends nonlinearly on the porosity and the reduction is relatively more pronounced than for mode I.","Cohesive elements; Composite materials; Multiscale fracture; Representative surface element; Voids","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2019-08-01","","","Novel Aerospace Materials","","",""
"uuid:eb392c8c-c761-4ef2-8e0d-74045ea063e7","http://resolver.tudelft.nl/uuid:eb392c8c-c761-4ef2-8e0d-74045ea063e7","Experimental studies of furfural production from water hyacinth (Eichhornia Crassipes)","Poomsawat, W. (TU Delft Large Scale Energy Storage); Tsalidis, G.A. (TU Delft Large Scale Energy Storage); Tsekos, C. (TU Delft Large Scale Energy Storage); de Jong, W. (TU Delft Large Scale Energy Storage)","","2019","Furfural is a very promising product of lignocellulosic biomass-based biorefineries and has the potential to become a useful resource for further conversion and utilization. Aquatic plants show an enormous potential as feedstock since they do not compete for land use, and they require minimal water consumption in a biorefinery concept due to their very high water content. This work is focused on experimental studies of furfural production from water hyacinth (Eichhornia crassipes) by means of aqueous, acid-catalyzed dehydration. The temperature range of the process, and the acid and seawater presence were chosen based on the previous relevant studies. The aim of the study was to determine whether water hyacinth is suitable for furfural production. The experiments were performed between 160°C and 200°C with a water hyacinth concentration of 2 wt%. The results suggest that the effects of acid catalyst presence on biomass dehydration are similar to the case of pure pentose dehydration. Furthermore, the addition of seawater did not have a positive catalytic effect in terms of the furfural yield. The maximum yield was 53.2 mol% based on the C5 sugar content in the original biomass. The furfural yield of 7.9 wt% of water hyacinth input was comparable to the yield of feedstocks such as corn cob, bagasse, and oat's residue and higher than the cases of rice straw or hulls. Thanks to the comparatively high pentose potential, water hyacinth shows promising results as a candidate feedstock for furfural production. A certain variability of pentosan should be taken into account, as the chemical composition of the plant depends on the source and harvesting seasons.","acid hydrolysis; biorefinery; furfural; seawater; water hyacinth (Eichhornia Crassipes)","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:48bee6f6-d245-46e6-997a-25312afda070","http://resolver.tudelft.nl/uuid:48bee6f6-d245-46e6-997a-25312afda070","Enhanced contrast acoustic-resolution photoacoustic microscopy using double-stage delay-multiply-and-sum beamformer for vasculature imaging","Mozaffarzadeh, M. (TU Delft ImPhys/Acoustical Wavefield Imaging); Varnosfaderani, Mehdi H.H. (Tarbiat Modares University); Sharma, Arunima (Nanyang Technological University); Pramanik, Manojit (Nanyang Technological University); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC)","","2019","In acoustic-resolution photoacoustic microscopy (AR-PAM) systems, the lateral resolution in the focal zone of the ultrasound (US) transducer is determined by the numerical aperture (NA) of the transducer. To have a high lateral resolution, a large NA is used. However, the larger the NA, the smaller the depth of focus [DOF]. As a result, the lateral resolution is deteriorated at depths out of the focal region. The synthetic aperture focusing technique (SAFT) along with a beamformer can be used to improve the resolution outside the focal region. In this work, for image formation in AR-PAM, we propose the double-stage delay-multiply-and-sum (DS_DMAS) algorithm to be combined with SAFT. The proposed method is evaluated experimentally using hair targets and in vivo vasculature imaging. It is shown that DS_DMAS provides a higher resolution and contrast compared to other methods. For the B-mode images obtained using the hair phantom, the proposed method reduces the average noise level for all the depths by about 134%, 57% and 23%, compared to the original low- resolution, SAFT+DAS and SAFT+DMAS methods, respectively. All the results indicate that the proposed method can be an appropriate algorithm for image formation in AR-PAM systems.","acoustic-resolution photoacoustic microscopy; contrast enhancement; synthetic aperture focusing technique; vasculature imaging; virtual source","en","journal article","","","","","","","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:e3d4408c-72a0-48f4-ae58-5f7f2898ff45","http://resolver.tudelft.nl/uuid:e3d4408c-72a0-48f4-ae58-5f7f2898ff45","Maximizing annual yield of bifacial photovoltaic noise barriers","Faturrochman, G.J. (Solar Energy Application Centre); de Jong, M.M. (Solar Energy Application Centre); Santbergen, R. (TU Delft Photovoltaic Materials and Devices); Folkerts, W. (Solar Energy Application Centre); Zeman, M. (TU Delft Electrical Sustainable Energy); Smets, A.H.M. (TU Delft Photovoltaic Materials and Devices)","","2018","In this work we consider noise barriers with integrated photovoltaic modules. The novelty is that bifacial modules are considered. A full scale bifacial photovoltaic noise barrier was built and its power output was monitored. In addition we developed an advanced numerical model for predicting this power output for given weather conditions. Excellent agreement was found between the measured power output and the model prediction. Next we used this model to demonstrate the effects of the orientation, tilt, location, cell position and bypass-diode configuration on the annual energy yield of bifacial photovoltaic noise barriers.","Annual energy yield; Bifacial; BIPV; Noise barrier; Photovoltaic","en","journal article","","","","","","","","2020-02-13","","Electrical Sustainable Energy","Photovoltaic Materials and Devices","","",""
"uuid:d9668c81-01da-4ae6-beaa-a910f8d1037c","http://resolver.tudelft.nl/uuid:d9668c81-01da-4ae6-beaa-a910f8d1037c","Acoustic characterization of a miniature matrix transducer for pediatric 3D transesophageal echocardiography","Daeichin, V. (TU Delft ImPhys/Acoustical Wavefield Imaging); Bera, D. (Erasmus MC); Raghunathan, S.B. (TU Delft ImPhys/Acoustical Wavefield Imaging); Shabanimotlagh, M. (TU Delft ImPhys/Acoustical Wavefield Imaging); Chen, Z. (TU Delft Electronic Instrumentation); Chen, C. (TU Delft Electronic Instrumentation); Noothout, E.C. (TU Delft ImPhys/Acoustical Wavefield Imaging); Vos, H.J. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC)","","2018","This paper presents the design, fabrication and characterization of a miniature PZT-on-CMOS matrix transducer for real-time pediatric 3-dimensional (3D) transesophageal echocardiography (TEE). This 3D TEE probe consists of a 32 × 32 array of PZT elements integrated on top of an Application Specific Integrated Circuit (ASIC). We propose a partitioned transmit/receive array architecture wherein the 8 × 8 transmitter elements, located at the centre of the array, are directly wired out and the remaining receive elements are grouped into 96 sub-arrays of 3 × 3 elements. The echoes received by these sub-groups are locally processed by micro-beamformer circuits in the ASIC that allow pre-steering up to ±37°. The PZT-on-CMOS matrix transducer has been characterized acoustically and has a centre frequency of 5.8 MHz, -6 dB bandwidth of 67%, a transmit efficiency of 6 kPa/V at 30 mm, and a receive dynamic range of 85 dB with minimum and maximum detectable pressures of 5 Pa and 84 kPa respectively. The properties are very suitable for a miniature pediatric real-time 3D TEE probe.","ASIC; micro-beamforming; pediatric matrix transducer; Transesophageal echocardiography; volumetric imaging","en","journal article","","","","","","Accepted author manuscript","","2019-07-30","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:1f58ad60-9271-455b-9bf8-5b90929c46a9","http://resolver.tudelft.nl/uuid:1f58ad60-9271-455b-9bf8-5b90929c46a9","Column chromatography for separation and fractionation of flavor-active esters on hydrophobic resins and simulation of breakthrough behavior","Saffarionpour, S. (TU Delft BT/Bioprocess Engineering); de Jong, Tessa F.; van der Wielen, L.A.M. (TU Delft BT/Bioprocess Engineering; University of Limerick); Brouwer, Eric (Heineken Supply Chain); Ottens, M. (TU Delft BT/Bioprocess Engineering)","","2019","For simulating an adsorption/elution step for separation and recovery of flavor-active esters in beer in the presence of ethanol at various temperatures, and validating the predicted breakthrough behavior, equilibrium data on concentration of each ester is required. This work evaluates the application of frontal analysis method (FA) for prediction of breakthrough behavior for adsorption of ethyl acetate, and determination of equilibrium concentrations and binding capacity for competitive adsorption of four major flavor-active esters in beer (i.e. ethyl acetate, isopentyl acetate, ethyl 4-methylpentanoate, and ethyl hexanoate), together with improvement of the obtained results, through fraction collection, and offline analysis, on columns packed with hydrophobic resins, Amberlite XAD16N and Sepabeads SP20SS. Single-component adsorption of ethyl acetate reveals a shorter breakthrough time, and higher slope of breakthrough curve for adsorption on SP20SS, due to smaller particle size, (50–100 µm), and enhanced mass transfer characteristics of this resin. Competitive frontal analysis tests, neatly demonstrate that increase in temperature is not favorable for adsorption but aids the elution step, 63–100% recovery of flavors at 333.15 K in comparison to 40–80% recovery at 298.15 K. Lower binding capacity of esters and shorter adsorption/elution cycle time is achieved at higher ethanol concentration and cyclic operation simulated under non-isothermal condition, exhibit higher accuracy between predicted and experimental breakthrough curves for XAD16N. A cyclic operation is simulated, for a larger scale column, for two scenarios, separation of ethyl acetate and complete separation of all flavor-active esters in the mixture. For more detailed prediction of breakthrough behavior, the influence of other components present in process streams needs to be investigated on competitive adsorption of esters.","Adsorption; Flavor-active esters; Fractionation; Frontal analysis; Simulation","en","journal article","","","","","","","","","","","BT/Bioprocess Engineering","","",""
"uuid:461c9a2c-bc4c-459b-96a7-5af86dfc0b52","http://resolver.tudelft.nl/uuid:461c9a2c-bc4c-459b-96a7-5af86dfc0b52","Adaption to glucose limitation is modulated by the pleotropic regulator CcpA, independent of selection pressure strength","Price, Claire E. (Rijksuniversiteit Groningen; Student TU Delft); Branco Dos Santos, Filipe (Vrije Universiteit Amsterdam; Swammerdam Institute for Life Sciences; Student TU Delft); Hesseling, Anne (Rijksuniversiteit Groningen); Uusitalo, Jaakko J. (Rijksuniversiteit Groningen); Bachmann, Herwig (Vrije Universiteit Amsterdam; Student TU Delft); Benavente, Vera (Vrije Universiteit Amsterdam); Goel, A. (TU Delft OLD BT/Cell Systems Engineering; Vrije Universiteit Amsterdam); Berkhout, Jan (Vrije Universiteit Amsterdam); de Jong, A. (Rijksuniversiteit Groningen)","","2019","Background: A central theme in (micro)biology is understanding the molecular basis of fitness i.e. which strategies are successful under which conditions; how do organisms implement such strategies at the molecular level; and which constraints shape the trade-offs between alternative strategies. Highly standardized microbial laboratory evolution experiments are ideally suited to approach these questions. For example, prolonged chemostats provide a constant environment in which the growth rate can be set, and the adaptive process of the organism to such environment can be subsequently characterized. Results: We performed parallel laboratory evolution of Lactococcus lactis in chemostats varying the quantitative value of the selective pressure by imposing two different growth rates. A mutation in one specific amino acid residue of the global transcriptional regulator of carbon metabolism, CcpA, was selected in all of the evolution experiments performed. We subsequently showed that this mutation confers predictable fitness improvements at other glucose-limited growth rates as well. In silico protein structural analysis of wild type and evolved CcpA, as well as biochemical and phenotypic assays, provided the underpinning molecular mechanisms that resulted in the specific reprogramming favored in constant environments. Conclusion: This study provides a comprehensive understanding of a case of microbial evolution and hints at the wide dynamic range that a single fitness-enhancing mutation may display. It demonstrates how the modulation of a pleiotropic regulator can be used by cells to improve one trait while simultaneously work around other limiting constraints, by fine-tuning the expression of a wide range of cellular processes.","Evolution; Lactic acid bacteria; Systems biology","en","journal article","","","","","","","","","","","OLD BT/Cell Systems Engineering","","",""
"uuid:1ffb08c6-f447-46d9-a775-2120adcefa6e","http://resolver.tudelft.nl/uuid:1ffb08c6-f447-46d9-a775-2120adcefa6e","Making Ours Mine: Increasing Consumer Acceptance of Access-Based PSS through Temporary Product Customisation","Tunn, V.S.C. (TU Delft Circular Product Design); Fokker, Richard (Student TU Delft); Luijkx, K.A. (Student TU Delft); de Jong, S.A.M. (Student TU Delft); Schoormans, J.P.L. (TU Delft Responsible Marketing and Consumer Behavior)","","2019","Access-based product-service systems (AB-PSS) have the potential to lower environmental impacts. Currently, a lack of consumer acceptance and, consequently, low adoption levels of AB-PSS are challenges preventing the realisation of their sustainability potential. This study proposes temporary product customisation to lower barriers for the acceptance of AB-PSS.We investigated whether customisation through modifying the appearance of an easily changeable attribute of a typical product, and thereby changing the product personality, could improve consumer acceptance while limiting the impact on sustainability. To explore this, a 3 × 1 between-group design experiment was conducted with consumers who are familiar with offerings similar to the AB-PSS we tested. The results indicate that respondents have a strong preference, as is widely recognised, for typical products in an AB-PSS. Infusing meaning and intangible value into accessed products through customisation can simultaneously lead to wider acceptance in the market and individual consumers' satisfaction. Our findings confirm that consumer acceptance increases if a product fulfils intangible needs along with functionality needs. The results can be used to think about new ways in which product design can enhance the diffusion of AB-PSS in the consumer market.","Circular economy; Consumer acceptance; Customisation; Diffusion; Intangible value; Personalisation; Product design; Product-service system; Typicality","en","journal article","","","","","","","","","","","Circular Product Design","","",""
"uuid:1fe4f22b-e885-4f56-aeb8-419efecf5f82","http://resolver.tudelft.nl/uuid:1fe4f22b-e885-4f56-aeb8-419efecf5f82","Putting the privacy paradox to the test: Online privacy and security behaviors among users with technical knowledge, privacy awareness, and financial resources","Barth, Susanne (University of Twente); de Jong, Menno D.T. (University of Twente); Junger, M. (University of Twente); Hartel, P.H. (TU Delft Cyber Security; University of Twente); Roppelt, Janina C. (University of Twente)","","2019","Research shows that people's use of computers and mobile phones is often characterized by a privacy paradox: Their self-reported concerns about their online privacy appear to be in contradiction with their often careless online behaviors. Earlier research into the privacy paradox has a number of caveats. Most studies focus on intentions rather than behavior and the influence of technical knowledge, privacy awareness, and financial resources is not systematically ruled out. This study therefore tests the privacy paradox under extreme circumstances, focusing on actual behavior and eliminating the effects of a lack of technical knowledge, privacy awareness, and financial resources. We designed an experiment on the downloading and usage of a mobile phone app among technically savvy students, giving them sufficient money to buy a paid-for app. Results suggest that neither technical knowledge and privacy awareness nor financial considerations affect the paradoxical behavior observed in users in general. Technically-skilled and financially independent users risked potential privacy intrusions despite their awareness of potential risks. In their considerations for selecting and downloading an app, privacy aspects did not play a significant role; functionality, app design, and costs appeared to outweigh privacy concerns.","Apps; Mobile phones; Privacy intrusion; Privacy paradox; Privacy valuation","en","journal article","","","","","","","","","","","Cyber Security","","",""
"uuid:b303a253-3e41-49bf-9029-91fcd9a51236","http://resolver.tudelft.nl/uuid:b303a253-3e41-49bf-9029-91fcd9a51236","Modeling the electrochemical conversion of carbon dioxide to formic acid or formate at elevated pressures","Morrison, A.R.T. (TU Delft Large Scale Energy Storage); van Beusekom, Vincent (Student TU Delft); Ramdin, M. (TU Delft Engineering Thermodynamics); van den Broeke, L.J.P. (TU Delft Engineering Thermodynamics); Vlugt, T.J.H. (TU Delft Engineering Thermodynamics); de Jong, W. (TU Delft Large Scale Energy Storage)","","2019","In this work a model of an elevated pressure CO2 electrolyzer producing primarily formate or formic acid is presented. It consists of three parts: A model of the bulk electrolyte, the diffusion layer, and the electrode surface. Data from the literature was used to validate both the bulk portion of the model, as well as the overall model. Results from the literature were further explored and explained by reference to the model and faradaic efficiency is predicted very well (R-Square of 0.99 for the fitted data, and 0.98 for the non-fitted data). The primary effect of increasing the pressure on a CO2 electrolyzer is seen to be increasing the maximum attainable partial current density, while the faradaic efficiency and specific energy of formation plateau at pressures above 10-20 bar, at 95% and of 3.7 kWh/kg, respectively. Unlike the efficiencies, the profitability of running a reactor increases with pressure, following a similar trend as partial current density, showing the importance of this quantity as a performance metric of a CO2 electrolyzer. In general this work shows the utility of a model of this sort in the design, evaluation and operation of CO2 electrolyzers.","Electrochemical Engineering; Energy Conversion; Industrial Electrolysis; CO2 electroreduction; High Pressure Electrolyzer; Simulation","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:1d52fd86-f73b-4c72-a89d-985a88cdcfd8","http://resolver.tudelft.nl/uuid:1d52fd86-f73b-4c72-a89d-985a88cdcfd8","Value of travel time as a function of comfort","Kouwenhoven, M.L.A. (TU Delft Transport and Logistics; Significance); de Jong, Gerard (University of Leeds; Significance)","","2018","The value of travel time can theoretically be defined as the opportunity cost of travel minus the direct utility from spending the time during the trip. This paper searches for empirical evidence to support this formulation. We show that travellers who indicate that a shorter trip duration is useful or a longer trip duration is very inconvenient have a higher value of travel time. Furthermore, we show that people who can spend their travel time usefully have a lower value of travel time. Finally, the availability of a computer, laptop etc. during the trip increases the probability of travel time being useful. This study determines the sizes of these effects in a case study for The Netherlands. This is important since the value of travel time is likely to change over time. The outcomes of this paper can be used to estimate the size of the expected reduction in value of travel time as a result of future comfort improvements that increase the possibility to work, read a book, watch a movie and communicate during a trip.","Comfort; Cost-benefit analysis; Discrete choice model; Value of travel time","en","journal article","","","","","","","","2020-06-14","","","Transport and Logistics","","",""
"uuid:fe16639c-0ca3-441b-b48b-fe3a00b4b3b7","http://resolver.tudelft.nl/uuid:fe16639c-0ca3-441b-b48b-fe3a00b4b3b7","Designing and validating a PVA liver phantom with respiratory motion for needle-based interventions","de Jong, T.L. (TU Delft Medical Instruments & Bio-Inspired Technology); Moelker, Adriaan (Erasmus MC); Dankelman, J. (TU Delft Medical Instruments & Bio-Inspired Technology); van den Dobbelsteen, J.J. (TU Delft Medical Instruments & Bio-Inspired Technology)","","2019","Purpose: The purpose is to design and validate an anthropomorphic polyvinyl alcohol (PVA) liver phantom with respiratory motion to simulate needle-based interventions. Such a system can, for example, be used as a validation tool for novel needles. Methods: Image segmentations of CT scans of four patients during inspiration and expiration were used to measure liver and rib displacement. An anthropomorphic liver mold based on a CT scan was 3D printed and filled with 5% w/w PVA-to-water, undergoing two freeze–thaw cycles, in addition to a 3D-printed compliant rib cage. They were both held in place by a PVA abdominal phantom. A sinusoidal motion vector, based on the measured liver displacement, was applied to the liver phantom by means of a motion stage. Liver, rib cage and needle deflection were tracked by placing electromagnetic sensors on the phantom. Liver and rib cage phantom motion was validated by comparison with the CT images of the patients, whereas needle deflection was compared with the literature. Results: CT analysis showed that from the state of expiration to inspiration, the livers moved predominantly toward the right (mean: 2 mm, range: − 11 to 11 mm), anterior (mean: 15 mm, range: 9–21 mm) and caudal (mean: 16 mm, range: 6–24 mm) direction. The mechatronic design of the liver phantom gives the freedom to set direction and amplitude of the motion and was able to mimic the direction of liver motion of one patient. Needle deflection inside the phantom increased from 1.6 to 3.8 mm from the initial expiration state to inspiration. Conclusions: The developed liver phantom allows for applying different motion patterns and shapes/sizes and thus allows for patient-specific simulation of needle-based interventions. Moreover, it is able to mimic appropriate respiratory motion and needle deflection as observed in patients.","Interventional radiology; Liver phantom; Needle deflection; Respiratory motion","en","journal article","","","","","","","","","","","Medical Instruments & Bio-Inspired Technology","","",""
"uuid:f32ef57f-337b-41a6-9dc0-81ee92f1a726","http://resolver.tudelft.nl/uuid:f32ef57f-337b-41a6-9dc0-81ee92f1a726","Loss of androgen receptor signaling in prostate cancer-associated fibroblasts (CAFs) promotes CCL2- and CXCL8-mediated cancer cell migration","Cioni, Bianca (Netherlands Cancer Institute); Nevedomskaya, Ekaterina (Netherlands Cancer Institute; Oncode Institute); Melis, Monique H.M. (Netherlands Cancer Institute); van Burgsteden, Johan (Netherlands Cancer Institute); Stelloo, Suzan (Netherlands Cancer Institute; Student TU Delft); Hodel, Emma (Netherlands Cancer Institute); Spinozzi, Daniele (Netherlands Cancer Institute); de Jong, Jeroen (Netherlands Cancer Institute); Wessels, L.F.A. (TU Delft Pattern Recognition and Bioinformatics; Netherlands Cancer Institute; Oncode Institute)","","2018","Fibroblasts are abundantly present in the prostate tumor microenvironment (TME), including cancer-associated fibroblasts (CAFs) which play a key role in cancer development. Androgen receptor (AR) signaling is the main driver of prostate cancer (PCa) progression, and stromal cells in the TME also express AR. High-grade tumor and poor clinical outcome are associated with low AR expression in the TME, which suggests a protective role of AR signaling in the stroma against PCa development. However, the mechanism of this relation is not clear. In this study, we isolated AR-expressing CAF-like cells. Testosterone (R1881) exposure did not affect CAF-like cell morphology, proliferation, or motility. PCa cell growth was not affected by culturing in medium from R1881-exposed CAF-like cells; however, migration of PCa cells was inhibited. AR chromatin immune precipitation sequencing (ChIP-seq) was performed and motif search suggested that AR in CAF-like cells bound the chromatin through AP-1-elements upon R1881 exposure, inducing enhancer-mediated AR chromatin interactions. The vast majority of chromatin binding sites in CAF-like cells were unique and not shared with AR sites observed in PCa cell lines or tumors. AR signaling in CAF-like cells decreased expression of multiple cytokines; most notably CCL2 and CXCL8 and both cytokines increased migration of PCa cells. These results suggest direct paracrine regulation of PCa cell migration by CAFs through AR signaling.","androgen receptor; cancer cell migration; cancer-associated fibroblasts; CCL2; CXCL8; EMT; prostate cancer","en","journal article","","","","","","","","","","","Pattern Recognition and Bioinformatics","","",""
"uuid:0107fd15-eb6e-4229-9c7b-f23e9c44cb66","http://resolver.tudelft.nl/uuid:0107fd15-eb6e-4229-9c7b-f23e9c44cb66","Tomographic PIV in a model of the left ventricle: 3D flow past biological and mechanical heart valves","Saaid, Hicham (Universiteit Gent); Voorneveld, Jason (Erasmus MC); Schinkel, C.V. (TU Delft ChemE/O&O groep); Westenberg, Jos (Leiden University Medical Center); Gijsen, F.J.H. (Erasmus MC); Segers, Patrick (Universiteit Gent); Verdonck, Pascal (Universiteit Gent); de Jong, N. (Erasmus MC); Kenjeres, S. (TU Delft ChemE/Transport Phenomena; TU Delft ChemE/Chemical Engineering)","","2019","Left ventricular flow is intrinsically complex, three-dimensional and unsteady. Its features are susceptible to cardiovascular pathology and treatment, in particular to surgical interventions involving the valves (mitral valve replacement). To improve our understanding of intraventricular fluid mechanics and the impact of various types of prosthetic valves thereon, we have developed a custom-designed versatile left ventricular phantom with anatomically realistic moving left ventricular membrane. A biological, a tilting disc and a bileaflet valve (in two different orientations) were mounted in the mitral position and tested under the same settings. To investigate 3D flow within the phantom, a four-view tomographic particle image velocimetry setup has been implemented. The results compare side-by-side the evolution of the 3D flow topology, vortical structures and kinetic energy in the left ventricle domain during the cardiac cycle. Except for the tilting disc valve, all tested prosthetic valves induced a crossed flow path, where the outflow crosses the inflow path, passing under the mitral valve. The biological valve shows a strong jet with a peak velocity about twice as high compared to all mechanical heart valves, which makes it easier to penetrate deeply into the cavity. Accordingly, the peak kinetic energy in the left ventricle in case of the biological valve is about four times higher than the mechanical heart valves. We conclude that the tomographic particle imaging velocimetry setup provides a useful ground truth measurement of flow features and allows a comparison of the effects of different valve types on left ventricular flow patterns.","Flow; Left ventricle; Particle image velocimetry; Prosthetic heart valves; Tomographic PIV","en","journal article","","","","","","Accepted Author Manuscript","","2020-04-22","","ChemE/Chemical Engineering","ChemE/O&O groep","","",""
"uuid:685357ee-e327-4be2-a397-027c1c1fcc7b","http://resolver.tudelft.nl/uuid:685357ee-e327-4be2-a397-027c1c1fcc7b","Optically Coherent Nitrogen-Vacancy Centers in Micrometer-Thin Etched Diamond Membranes","Ruf, M.T. (TU Delft QuTech Advanced Research Centre; TU Delft QID/Hanson Lab; Kavli institute of nanoscience Delft; Northwestern University); IJspeert, M. (TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); van Dam, S.B. (TU Delft QuTech Advanced Research Centre; TU Delft QID/Hanson Lab; Kavli institute of nanoscience Delft); de Jong, N. (TU Delft BUS/General; TU Delft QuTech Advanced Research Centre; TNO; Kavli institute of nanoscience Delft); van den Berg, J.H. (TU Delft Business Development; TU Delft QuTech Advanced Research Centre; TNO; Kavli institute of nanoscience Delft); Evers, G.P.H.; Hanson, R. (TU Delft QID/Hanson Lab; TU Delft QN/Hanson Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft)","","2019","Diamond membrane devices containing optically coherent nitrogen-vacancy (NV) centers are key to enable novel cryogenic experiments such as optical ground-state cooling of hybrid spin-mechanical systems and efficient entanglement distribution in quantum networks. Here, we report on the fabrication of a (3.4 ± 0.2) μm thin, smooth (surface roughness rq < 0.4 nm over an area of 20 μm by 30 μm) diamond membrane containing individually resolvable, narrow linewidth (< 100 MHz) NV centers. We fabricate this sample via a combination of high-energy electron irradiation, high-temperature annealing, and an optimized etching sequence found via a systematic study of the diamond surface evolution on the microscopic level in different etch chemistries. Although our particular device dimensions are optimized for cavity-enhanced entanglement generation between distant NV centers in open, tunable microcavities, our results have implications for a broad range of quantum experiments that require the combination of narrow optical transitions and micrometer-scale device geometry.","diamond nanofabrication; electron irradiation; Nitrogen-vacancy center; optical coherence; quantum information science","en","journal article","","","","","","","","","","Business Development","QID/Hanson Lab","","",""
"uuid:223b5f58-e21d-4690-bf8e-7a257cd80adf","http://resolver.tudelft.nl/uuid:223b5f58-e21d-4690-bf8e-7a257cd80adf","Navigating transitions for sustainable infrastructures - The case of a new high-speed railway station in Jingmen, China","Liu, X. (TU Delft Integral Design & Management); Schraven, D.F.J. (TU Delft Integral Design & Management); de Bruijne, M.L.C. (TU Delft Organisation & Governance); de Jong, Martin (Rotterdam School of Management; Fudan University); Hertogh, M.J.C.M. (TU Delft Integral Design & Management)","","2019","Sustainable development and Circular Economy (CE) have drawn massive attention worldwide. Construction practices consume large amounts of materials, resources and energy. Sustainability and CE could play a big role in reduction efforts. However, the potential influence of both concepts on the planning and construction of large infrastructures remains unexplored. This paper investigates how professionals involved in a high-speed railway station project in the Chinese city of Jingmen envision the use of sustainability and CE for the planning and construction of the railway station and its surrounding areas. We reviewed policy documents and interviewed local professionals with the Triple Bottom Line (TBL) framework. The analysis reveals opportunities for improvement towards sustainability and the interdependence between the dimensions in the TBL framework for the railway station and its surroundings. The case shows that local professionals identify ample opportunities for improvement (presented as ""sustainability ideas""), but none appear truly sustainable. These insights provide evidence that the hierarchical introduction of transition(s) creates a cognitive silo for local professionals when envisioning sustainability ideas. In the TBL framework, this study finds a useful and novel approach to break down the silos, because the TBL stresses the interdependence between the various sustainability dimensions.","China; Circular Economy (CE); Jingmen; Railway station; Sustainability; Transport infrastructure; Triple Bottom Line (TBL)","en","journal article","","","","","","","","","","","Integral Design & Management","","",""
"uuid:47047a66-4e71-4c25-ac76-502e98165bed","http://resolver.tudelft.nl/uuid:47047a66-4e71-4c25-ac76-502e98165bed","Reproducibility of Natural Shear Wave Elastography Measurements","Keijzer, L.B.H. (Erasmus MC); Strachinaru, Mihai (Erasmus MC); Bowen, Dan J. (Erasmus MC); Geleijnse, Marcel L. (Erasmus MC); van der Steen, A.F.W. (Erasmus MC); Bosch, Johan G. (Erasmus MC); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Vos, H.J. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC)","","2019","For the quantification of myocardial function, myocardial stiffness can potentially be measured non-invasively using shear wave elastography. Clinical diagnosis requires high precision. In 10 healthy volunteers, we studied the reproducibility of the measurement of propagation speeds of shear waves induced by aortic and mitral valve closure (AVC, MVC). Inter-scan was slightly higher but in similar ranges as intra-scan variability (AVC: 0.67 m/s (interquartile range [IQR]: 0.40–0.86 m/s) versus 0.38 m/s (IQR: 0.26–0.68 m/s), MVC: 0.61 m/s (IQR: 0.26–0.94 m/s) versus 0.26 m/s (IQR: 0.15–0.46 m/s)). For AVC, the propagation speeds obtained on different day were not statistically different (p = 0.13). We observed different propagation speeds between 2 systems (AVC: 3.23–4.25 m/s [Zonare ZS3] versus 1.82–4.76 m/s [Philips iE33]), p = 0.04). No statistical difference was observed between observers (AVC: p = 0.35). Our results suggest that measurement inaccuracies dominate the variabilities measured among healthy volunteers. Therefore, measurement precision can be improved by averaging over multiple heartbeats.","Elastography; High frame rate; Natural shear wave elastography; Shear waves; stiffness; Tissue elasticity imaging; Valve closure","en","journal article","","","","","","","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:92a296ad-626e-4bf0-b969-cd8774d32be6","http://resolver.tudelft.nl/uuid:92a296ad-626e-4bf0-b969-cd8774d32be6","Hydrographic and Biological Survey of a Surface-Intensified Anticyclonic Eddy in the Caribbean Sea","van der Boog, C.G. (TU Delft Environmental Fluid Mechanics); de Jong, M. F. (NIOZ Royal Netherlands Institute for Sea Research); Scheidat, M. (Wageningen University & Research); Leopold, M. F. (Wageningen University & Research); Geelhoed, S. C.V. (Wageningen University & Research); Schulz, K. (NIOZ Royal Netherlands Institute for Sea Research); Pietrzak, J.D. (TU Delft Environmental Fluid Mechanics); Katsman, C.A. (TU Delft Environmental Fluid Mechanics); Dijkstra, H.A. (Universiteit Utrecht)","","2019","In the Caribbean Sea, mesoscale anticyclonic ocean eddies impact the local ecosystem by mixing of low salinity river outflow with the nutrient-rich waters upwelling along the Venezuelan and Colombian coast. To gain insight into the physics and the ecological impact of these anticyclones, we performed a combined hydrographic and biological survey of one Caribbean anticyclone in February 2018. We found that the anticyclone had a radius of 90 km and was surface intensified with the strongest velocities (0.72 m/s) in the upper 150 m of the water column. Below, isopycnal displacements were found down to 700 dbar. The core of the anticyclone entrained waters from the Orinoco River plume and contained slightly elevated chlorophyll concentrations compared to the surroundings. At the edge of the anticyclone we observed higher densities of flying fish but not higher densities of predators like seabirds and cetaceans. Below the surface, a strong temperature inversion (0.98 °C) was present within a barrier layer. In addition, we found thermohaline staircases that originated from double diffusion processes within Tropical Atlantic Central Water.","anticyclone; barrier layer; Caribbean Sea; ecology; hydrographic; thermohaline staircases","en","journal article","","","","","","","","","","","Environmental Fluid Mechanics","","",""
"uuid:361f73a0-9c25-4e68-9671-9eed129df834","http://resolver.tudelft.nl/uuid:361f73a0-9c25-4e68-9671-9eed129df834","Combined Confocal Microscope and Brandaris 128 Ultra-High-Speed Camera","Beekers, D.I. (Erasmus MC); Lattwein, Kirby R. (Erasmus MC); Kouijzer, Joop J.P. (Erasmus MC); Langeveld, Simone A.G. (Erasmus MC); Vegter, M. (Erasmus MC); Beurskens, Robert (Erasmus MC); Mastik, F. (Erasmus MC); Verduyn Lunel, Rogier (Nikon, Amsterdam); van der Steen, A.F.W. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC)","","2019","Controlling microbubble-mediated drug delivery requires the underlying biological and physical mechanisms to be unraveled. To image both microbubble oscillation upon ultrasound insonification and the resulting cellular response, we developed an optical imaging system that can achieve the necessary nanosecond temporal and nanometer spatial resolutions. We coupled the Brandaris 128 ultra-high-speed camera (up to 25 million frames per second) to a custom-built Nikon A1R+ confocal microscope. The unique capabilities of this combined system are demonstrated with three experiments showing microbubble oscillation leading to either endothelial drug delivery, bacterial biofilm disruption, or structural changes in the microbubble coating. In conclusion, using this state-of-the-art optical imaging system, microbubble-mediated drug delivery can be studied with high temporal resolution to resolve microbubble oscillation and high spatial resolution and detector sensitivity to discern cellular response. Combining these two imaging technologies will substantially advance our knowledge on microbubble behavior and its role in drug delivery.","Bacteria; Confocal microscopy; Drug delivery; Fluorescence microscopy; High-speed imaging; Lipid coating; Microbubble; Sonoporation; Ultrasound; Ultrasound contrast agents","en","journal article","","","","","","","","","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:453cd768-2eeb-4ca0-81e3-a3e16dec33cc","http://resolver.tudelft.nl/uuid:453cd768-2eeb-4ca0-81e3-a3e16dec33cc","An automated workflow based on hip shape improves personalized risk prediction for hip osteoarthritis in the CHECK study","Gielis, W. P. (University Medical Center Utrecht); Weinans, Harrie (TU Delft Biomaterials & Tissue Biomechanics; University Medical Center Utrecht); Welsing, P. M.J. (University Medical Center Utrecht); van Spil, W. E. (University Medical Center Utrecht); Agricola, R. (Erasmus MC); Cootes, T. F. (The University of Manchester); de Jong, P. A. (University Medical Center Utrecht); Lindner, C. (The University of Manchester)","","2020","Objective: To design an automated workflow for hip radiographs focused on joint shape and tests its prognostic value for future hip osteoarthritis. Design: We used baseline and 8-year follow-up data from 1,002 participants of the CHECK-study. The primary outcome was definite radiographic hip osteoarthritis (rHOA) (Kellgren–Lawrence grade ≥2 or joint replacement) at 8-year follow-up. We designed a method to automatically segment the hip joint from radiographs. Subsequently, we applied machine learning algorithms (elastic net with automated parameter optimization) to provide the Shape-Score, a single value describing the risk for future rHOA based solely on joint shape. We built and internally validated prediction models using baseline demographics, physical examination, and radiologists scores and tested the added prognostic value of the Shape-Score using Area-Under-the-Curve (AUC). Missing data was imputed by multiple imputation by chained equations. Only hips with pain in the corresponding leg were included. Results: 84% were female, mean age was 56 (±5.1) years, mean BMI 26.3 (±4.2). Of 1,044 hips with pain at baseline and complete follow-up, 143 showed radiographic osteoarthritis and 42 were replaced. 91.5% of the hips had follow-up data available. The Shape-Score was a significant predictor of rHOA (odds ratio per decimal increase 5.21, 95%-CI (3.74–7.24)). The prediction model using demographics, physical examination, and radiologists scores demonstrated an AUC of 0.795, 95%-CI (0.757–0.834). After addition of the Shape-Score the AUC rose to 0.864, 95%-CI (0.833–0.895). Conclusions: Our Shape-Score, automatically derived from radiographs using a novel machine learning workflow, may strongly improve risk prediction in hip osteoarthritis.","Epidemiology; Hip osteoarthritis; Imaging; Statistical shape analysis","en","journal article","","","","","","","","","","","Biomaterials & Tissue Biomechanics","","",""
"uuid:4ca50758-2452-4ab9-8959-4b99b8e1fd7a","http://resolver.tudelft.nl/uuid:4ca50758-2452-4ab9-8959-4b99b8e1fd7a","Dynamic modeling of the heat pipe-assisted annealing line","Çelik, M. (TU Delft Large Scale Energy Storage); Patki, Mrunal (Student TU Delft); Paulussen, Geert (Tata Steel Europe Limited); de Jong, W. (TU Delft Large Scale Energy Storage); Boersma, B.J. (TU Delft Process and Energy; TU Delft Energy Technology)","","2019","In a conventional continuous annealing line, the energy supplied to steel strip during heating is not recovered while cooling it. Therefore, an alternative heat transfer technology for energy efficient continuous annealing of steel was developed. This technology enables reusing the heat extracted during cooling of the strip in the heating part of the process. This is achieved by thermally linking the cooling strip to the heating strip via multiple rotating heat pipes. In this context, the dynamic simulation of a full heat pipe assisted annealing line is performed. The dynamic simulation consists of the interaction of computational building blocks, each comprising of a rotating heat pipe and strip parts wrapped around the heat pipe. The simulations are run for different installation configurations and operational settings, with the heat pipe number varying between 50 and 100 and with varying strip line speed and dimensions. The heat pipes are sized to be 0.5 m in diameter and 3 m in length. The simulation results show that the equipment is capable of satisfying the thermal cycle requirements of annealing both at steady-state and during transition between steady-states following changes in boundary conditions. With this concept, energy savings of up to 70% are feasible.","","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2020-01-22","","Process and Energy","Large Scale Energy Storage","","",""
"uuid:f9dc24fc-5660-4a34-ae0b-12cb9efd7c53","http://resolver.tudelft.nl/uuid:f9dc24fc-5660-4a34-ae0b-12cb9efd7c53","Higher-order derivatives of rigid body dynamics with application to the dynamic balance of spatial linkages","de Jong, J. J. (University of Twente); Müller, A. (Johannes Kepler University); Herder, J.L. (TU Delft Precision and Microsystems Engineering)","","2021","Dynamic balance eliminates the fluctuating reaction forces and moments induced by high-speed robots that would otherwise cause undesired base vibrations, noise and accuracy loss. Many balancing procedures, such as the addition of counter-rotating inertia wheels, increase the complexity and motor torques. There exist, however, a small set of closed-loop linkages that can be balanced by a specific design of the links' mass distribution, potentially leading to simpler and cost-effective solutions. Yet, the intricacy of the balance conditions hinder the extension of this set of linkages. Namely, these conditions contain complex closed-form kinematic models to express them in minimal coordinates. This paper presents an alternative approach by satisfying all higher-order derivatives of the balance conditions, thus avoiding finite closed-form kinematic models while providing a full solution for arbitrary linkages. The resulting dynamic balance conditions are linear in the inertia parameters such that a null space operation, either numeric or symbolic, yield the full design space. The concept of inertia transfer provides a graphical interpretation to retain intuition. A novel dynamically balanced 3-RSR spatially moving mechanism is presented together with known examples to illustrate the method.","Dynamic balance; Higher-order derivatives; Momentum; Multipole representation; Parallel mechanisms; Parameter-linear form; Rigid body dynamics; Screw theory","en","journal article","","","","","","","","","","Precision and Microsystems Engineering","","","",""
"uuid:2ca7938e-a02c-4bc6-81a4-bb7237f1dbf4","http://resolver.tudelft.nl/uuid:2ca7938e-a02c-4bc6-81a4-bb7237f1dbf4","From city promotion via city marketing to city branding: Examining urban strategies in 23 Chinese cities","Ma, W. (TU Delft Organisation & Governance; Harbin Institute of Technology); de Jong, W.M. (TU Delft Organisation & Governance; Erasmus Universiteit Rotterdam; Fudan University); Hoppe, T. (TU Delft Organisation & Governance); de Bruijne, M.L.C. (TU Delft Organisation & Governance)","","2021","City promotion, city marketing and city branding are all frequently mentioned and examined in the literature on urban governance. Based on the goals and characteristics of different city branding strategies, this study identifies a growing level of sophistication from city promotion via city marketing to city branding and proposes that the degree of urban development of cities is positively related to the use of branding strategies. This proposition is tested among 23 Chinese cities: 21 cities in Guangdong province and two in the Special Administrative Regions – Hong Kong and Macao. The results show a positive correlation between the use of city promotion, city marketing and city branding strategies and a city's level of urban development. Only the largest and wealthiest cities, and those with the strongest tertiary sector report on the use of policies which indicate city branding. The strength of the primary sector is significantly and negatively related to all three identified forms of branding strategy. Furthermore, significant positive statistical inter-relationships exist between the different branding strategies, which confirm the existence of complex relations and overlaps between them. Our findings suggest that local governments should align their city branding strategies with their development goals.","China; City branding; City marketing; City promotion; Progression proposition; Urban governance","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:f7968e8b-5337-440f-84e6-1baf94f5868a","http://resolver.tudelft.nl/uuid:f7968e8b-5337-440f-84e6-1baf94f5868a","Supercritical water gasification of wet biomass residues from farming and food production practices: lab-scale experiments and comparison of different modelling approaches","Mohammadzadeh Moghaddam, E. (TU Delft Large Scale Energy Storage); Goel, Avishek (Student TU Delft); Siedlecki, Marcin (Research and Innovation Centre Pro-Akademia); Michalska, Karin (Research and Innovation Centre Pro-Akademia); Yakaboylu, O. (Tata Steel Europe Limited); de Jong, W. (TU Delft Large Scale Energy Storage)","","2021","Globally, large amounts of biomass wastes such as cattle manure, fruit/vegetable waste, and cheese whey residual streams are disposed of from farming and food processing industries. A promising approach to convert such biogenic residues into valuable biofuels is Supercritical Water Gasification (SCWG). A detailed investigation on SCWG of the mentioned wet biomass wastes has been performed to assess the thermodynamic behavior of such a complicated system. This is conducted by combining advanced models with a supplementary experimental study, providing deep insight into the behavior of the SCWG system for different bio-waste sources. For the modelling part, different approaches including global, constrained and thermal quasi-thermodynamic equilibria have been pursued to analyze the influence of operating parameters on the produced biogas quality. Furthermore, SCWG experiments were conducted using biomass samples provided by our industrial partner. Reasonable agreements were observed between experimental results and predictions from constrained and thermal-quasi equilibrium models, showing significant improvements over the global thermodynamic equilibrium model. Results showed that superimposition of carbon conversion efficiency together with the use of a constant molar amount of specific compounds can improve the accuracy of the global equilibrium model. Furthermore, comparisons between different models revealed the advantage of the thermal quasi-equilibrium model, which uses the “approach temperature” concept, over the constrained equilibrium model, by reducing the complexities inherent in superimposing multiple constraints. Overall, the thermal-quasi equilibrium approach has its advantages of lumping all the additional constraints used in the constrained equilibrium model into an effective approach temperature, offering (i) a better reproducibility of the experimental data point and (ii) a rigorous basis for scale-up calculation. The results of this study provide a better understanding of the SCWG process for different types of wet biomass feedstocks as result of applying advanced analytical approaches and comparing with experiments.","","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:846806a5-0063-4768-aa4a-ec67ef9f4587","http://resolver.tudelft.nl/uuid:846806a5-0063-4768-aa4a-ec67ef9f4587","Bypassing institutional barriers: New types of transit-oriented development in China","Song, Y. (TU Delft Organisation & Governance); de Jong, W.M. (Erasmus Universiteit Rotterdam; Fudan University); Stead, D. (TU Delft Spatial Planning and Strategy; Aalto University)","","2021","China is often viewed as an emerging experimental base for transit-oriented development (TOD) practices because of its rapid urban growth and development of mass transit networks. The implementation of TOD can be heavily influenced by institutional barriers to urban growth. However, some newly emerging types of TOD practice allow planners and decision-makers to bypass some of the institutional barriers and achieve a certain degree of integrated development. Current academic literature, however, has little to say on how these informal institutional solutions go around these barriers. This article aims to fill this gap by examining three different types of TOD practice as applied in Guangzhou and Shenzhen. We analysed and compared the origins and effects of abovementioned informal institutional arrangements under entrepreneurial governance. We found that land value capturing can replace the existing governance mode in which local government heavily relies on revenue from land-leasing and realise better integration of transit and land development. We conclude with several suggestions for institutional reform based on these new types of TOD experiments.","Entrepreneurial governance; Institutional barriers; Rail plus property development; Transit-adjacent development; Transit-oriented development; Transport hub; Urban governance","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:2143e10b-341e-4752-9eaa-deaff604d2f5","http://resolver.tudelft.nl/uuid:2143e10b-341e-4752-9eaa-deaff604d2f5","Sub-nanometer ceria-promoted Ni 13X zeolite catalyst for CO2 methanation","Wei, L. (TU Delft Large Scale Energy Storage); Grénman, Henrik (Åbo Akademi University); Haije, W.G. (TU Delft ChemE/Materials for Energy Conversion and Storage); Kumar, Narendra (Åbo Akademi University); Aho, Atte (Åbo Akademi University); Eränen, Kari (Åbo Akademi University); Wei, L. (TU Delft Sanitary Engineering); de Jong, W. (TU Delft Large Scale Energy Storage)","","2021","Sub-nanometer zeolite 13X-supported Ni-ceria catalysts were synthesized for CO2 methanation. XRD and SEM results show the structure and morphology of 13X zeolite after impregnation and calcination. Ce loading affected the catalysts’ metal dispersion, reducibility, basicity and acidity, and thence their activity and selectivity. STEM-EDX elemental mappings showed that Ce and Ni are predominantly highly dispersed. Ce has a positive effect on the reduction of NiO and leads to a relatively high number of medium basic sites with a low Ce loading. Highly stable 5%Ni2.5%Ce13X had high activity and nearly 100% CH4 selectivity in CO2 methanation at 360 °C, which is mainly due to the high dispersion of metals and relatively high amount of medium basic sites. It can be inferred that this catalyst synthesis strategy has great potential for good catalyst dispersion, since metal uptake by the zeolite is selective for the metal citrate complexes in solution.","Cerium citrate; Citrate complexes; CO methanation; Nickel citrate; Sub-nanometer nickel-ceria on zeolite 13X","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:b538112b-a2fa-4b07-8c41-2465e4702dbb","http://resolver.tudelft.nl/uuid:b538112b-a2fa-4b07-8c41-2465e4702dbb","The impact of lipid handling and phase distribution on the acoustic behavior of microbubbles","Langeveld, Simone A.G. (Erasmus MC); Beekers, Inés (Erasmus MC); Collado Lara, G. (Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Kooiman, Klazina (Erasmus MC)","","2021","Phospholipid-coated microbubbles are ultrasound contrast agents that can be employed for ultrasound molecular imaging and drug delivery. For safe and effective implementation, microbubbles must respond uniformly and predictably to ultrasound. Therefore, we investigated how lipid handling and phase distribution affected the variability in the acoustic behavior of microbubbles. Cholesterol was used to modify the lateral molecular packing of 1,2-distearoyl-sn-glycero-3phosphocholine (DSPC)-based microbubbles. To assess the effect of lipid handling, microbubbles were produced by a direct method, i.e., lipids directly dispersed in an aqueous medium or indirect method, i.e., lipids first dissolved in an organic solvent. The lipid phase and ligand distribution in the microbubble coating were investigated using confocal microscopy, and the acoustic response was recorded with the Brandaris 128 ultra-high-speed camera. In microbubbles with 12 mol% cholesterol, the lipids were miscible and all in the same phase, which resulted in more buckle formation, lower shell elasticity and higher shell viscosity. Indirect DSPC microbubbles had a more uniform response to ultrasound than direct DSPC and indirect DSPC-cholesterol microbubbles. The difference in lipid handling between direct and indirect DSPC microbubbles significantly affected the acoustic behavior. Indirect DSPC microbubbles are the most promising candidate for ultrasound molecular imaging and drug delivery applications.","Acoustic response; Cholesterol; Ligand distribution; Lipid phase; Microbubble; Phospholipid coating; Ultrasound contrast agents","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:53080155-c528-4f50-a779-414ac2a7df68","http://resolver.tudelft.nl/uuid:53080155-c528-4f50-a779-414ac2a7df68","Large-scale transportation and storage of wood pellets: Investigation of the change in physical properties","Gilvari, H. (TU Delft Large Scale Energy Storage; TU Delft Transport Engineering and Logistics); van Battum, Coen H.H. (Student TU Delft); van Dijk, Simon A. (Uniper Benelux NV); de Jong, W. (TU Delft Large Scale Energy Storage); Schott, D.L. (TU Delft Transport Engineering and Logistics)","","2021","The change in physical properties of wood pellets, with a focus on particle size distributions due to pellet breakage and attrition, was studied in a large-scale (∼450 ton/h) transportation system. Critical locations with a high probability of breakage through the whole transportation system were chosen and sampled to study the effect of transportation system design and operation on the mechanical properties of pellets. Bulk density, mechanical durability, moisture content, and particle size distribution of pellets were characterized for each sample. Analysis of variance showed that there were significant differences between the percentages of small particles (< 5.6 mm) in the samples taken at different locations, especially at one with a vertical free fall of 7.8 m. On average, this relatively long drop increased the proportion of particles < 5.6 mm in the samples from 8.73% to 14.09%, and that of particles < 3.15 mm from 4.82% to 9.01%. Moreover, the measurements showed a wide deviation in the mechanical durability values, between a minimum of 90.8% and a maximum of 98.7%, which were not correlated to the sampling points but related to pellet properties. It can be concluded that pellet transportation systems require more dedicated design strategies to prevent breakage and attrition.","Breakage; Durability; Fines and dust; Large-scale transportation; Mechanical degradation; Wood pellets","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:1cc6c5f8-8333-4cf1-8381-0985311b455c","http://resolver.tudelft.nl/uuid:1cc6c5f8-8333-4cf1-8381-0985311b455c","Liquid-Liquid Extraction of Formic Acid with 2-Methyltetrahydrofuran: Experiments, Process Modeling, and Economics","Laitinen, Antero T. (VTT Technical Research Center of Finland); Parsana, Vyomesh M. (Gujarat Technological University); Jauhiainen, Olli (VTT Technical Research Center of Finland); Huotari, Marco (VTT Technical Research Center of Finland); van den Broeke, L.J.P. (TU Delft Engineering Thermodynamics); de Jong, W. (TU Delft Large Scale Energy Storage); Vlugt, T.J.H. (TU Delft Engineering Thermodynamics); Ramdin, M. (TU Delft Engineering Thermodynamics)","","2021","Formic acid (FA) is an interesting hydrogen (H2) and carbon monoxide (CO) carrier that can be produced by the electrochemical reduction of carbon dioxide (CO2) using renewable energy. The separation of FA from water is challenging due to the strong (cross)association of the components and the presence of a high boiling azeotrope. For the separation of dilute FA solutions, liquid-liquid extraction is preferred over conventional distillation because distilling large amounts of water is very energy-intensive. In this study, we use 2-methyltetrahydrofuran (2-MTHF) to extract FA from the CO2 electrolysis process, which typically contains <20 wt % of FA. Vapor-liquid equilibrium (VLE) data of the binary system 2-MTHF-FA and liquid-liquid equilibrium (LLE) data of the ternary system 2-MTHF-FA-water are obtained. Continuous extraction and distillation experiments are performed to test the extraction power and recovery of 2-MTHF from the extract. The VLE and LLE data are used to design a hybrid extraction and distillation process to produce a commercial grade product (85 wt % of FA). A detailed economic analysis of this hybrid extraction-distillation process is presented and compared with the existing FA separation methods. It is shown that 2-MTHF is a cost-effective solvent for FA extraction from dilute streams (<20 wt % FA).","","en","journal article","","","","","","","","","","","Engineering Thermodynamics","","",""
"uuid:cfbe9b9c-4dff-43f3-a562-adad70b6f568","http://resolver.tudelft.nl/uuid:cfbe9b9c-4dff-43f3-a562-adad70b6f568","Exploring Multiple‐discreteness in Freight Transport. A Multiple Discrete Extreme Value Model Application for Grain Consolidators in Argentina","Tapia, Rodrigo Javier (TU Delft Transport and Planning; Universidade Federal do Rio Grande do Sul); de Jong, Gerard (University of Leeds); Larranaga, Ana M. (Universidade Federal do Rio Grande do Sul); Bettella Cybis, Helena B. (Universidade Federal do Rio Grande do Sul)","","2021","There are some examples where freight choices may be of a multiple discrete nature, especially the ones at more tactical levels of planning. Nevertheless, this has not been investigated in the literature, although several discrete-continuous models for mode/vehicle type and shipment size choice have been developed in freight transport. In this work, we propose that the decision of port and mode of the grain consolidators in Argentina is of a discrete-continuous nature, where they can choose more than one alternative and how much of their production to send by each mode. The Multiple Discrete Extreme Value Model (MDCEV) framework was applied to a stated preference data set with a response variable that allowed this multiple-discreteness. To our knowledge, this is the only application of the MDCEV in regional freight context. Free alongside ship price, freight transport cost, lead-time and travel time were included in the utility function and observed and random heterogeneity was captured by the interaction with the consolidator’s characteristics and random coefficients. In addition, different discrete choice models were used to compare the forecasting performance, willingness to pay measures and structure of the utility function against.","Freight modelling; Multiple Discrete Extreme Value Model; Willingness to pay","en","journal article","","","","","","","","","","","Transport and Planning","","",""
"uuid:cc3830da-709c-4621-87bb-a56e32867f89","http://resolver.tudelft.nl/uuid:cc3830da-709c-4621-87bb-a56e32867f89","Unravelling Decision-Making Processes on Location Choices for High-Speed Railway Stations in China: A Comparison of Shenzhen, Lanzhou and Jingmen","Wang, B. (TU Delft Urban Development Management); de Jong, W.M. (Erasmus Universiteit Rotterdam); van Bueren, Ellen (TU Delft Management in the Built Environment); Ersoy, A. (TU Delft Urban Development Management); Chen, Y. (TU Delft Urban Development Management)","","2021","Most High-Speed Railway (HSR) station areas in China can be found at the urban periphery or in suburban areas, a phenomenon that has often been criticised. While debate about the influence these location choices have on the economic and sustainable development of cities rages on, little attention has been paid to the decision-making processes leading to these locations. This paper investigates these processes by comparing HSR stations in three cities: Shenzhen, Lanzhou and Jingmen. Our findings can help actors involved in making location choices develop awareness of different interests and create the conditions for successful development of HSR station areas.","China; decision-making process; HSR station areas; policy networks; transport planning; urban development","en","journal article","","","","","","","","","","Management in the Built Environment","Urban Development Management","","",""
"uuid:ecb78b6d-5d7a-4ae9-9bb2-f2553781bab5","http://resolver.tudelft.nl/uuid:ecb78b6d-5d7a-4ae9-9bb2-f2553781bab5","NetSquid, a NETwork Simulator for QUantum Information using Discrete events","Coopmans, T.J. (TU Delft QID/Elkouss Group; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Knegjens, R.J. (TU Delft BUS/TNO STAFF; TU Delft QuTech Advanced Research Centre); Dahlberg, E.A. (TU Delft QID/Wehner Group; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Maier, D.J. (TU Delft QID/Wehner Group; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Nijsten, L.M.J. (TU Delft Business Development; TU Delft QuTech Advanced Research Centre); de Oliveira Filho, J.A. (TU Delft Business Development; TU Delft QuTech Advanced Research Centre); Papendrecht, M.N.G. (TU Delft QID/Software Group; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Rabbie, J. (TU Delft QID/Wehner Group; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Rozpedek, F.D. (TU Delft QID/Wehner Group; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Skrzypczyk, M.D. (TU Delft Electrical Engineering, Mathematics and Computer Science; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Wubben, L.C.J. (TU Delft Electrical Engineering, Mathematics and Computer Science; Kavli institute of nanoscience Delft); de Jong, W. (SURF, Amsterdam); Wehner, S.D.C. (TU Delft Quantum Internet Division; TU Delft Quantum Information and Software; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft)","","2021","In order to bring quantum networks into the real world, we would like to determine the requirements of quantum network protocols including the underlying quantum hardware. Because detailed architecture proposals are generally too complex for mathematical analysis, it is natural to employ numerical simulation. Here we introduce NetSquid, the NETwork Simulator for QUantum Information using Discrete events, a discrete-event based platform for simulating all aspects of quantum networks and modular quantum computing systems, ranging from the physical layer and its control plane up to the application level. We study several use cases to showcase NetSquid’s power, including detailed physical layer simulations of repeater chains based on nitrogen vacancy centres in diamond as well as atomic ensembles. We also study the control plane of a quantum switch beyond its analytically known regime, and showcase NetSquid’s ability to investigate large networks by simulating entanglement distribution over a chain of up to one thousand nodes.","","en","journal article","","","","","","","","","Electrical Engineering, Mathematics and Computer Science","Business Development","QID/Elkouss Group","","",""
"uuid:c850db7a-510c-43ec-86f0-2366dda471ec","http://resolver.tudelft.nl/uuid:c850db7a-510c-43ec-86f0-2366dda471ec","Theranostic Microbubbles with Homogeneous Ligand Distribution for Higher Binding Efficacy","Langeveld, Simone A.G. (Erasmus MC); Meijlink, Bram (Erasmus MC); Beekers, Inés (Erasmus MC; Ortec B.V.); Olthof, Mark (Erasmus MC); van der Steen, A.F.W. (Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Kooiman, Klazina (Erasmus MC)","","2022","Phospholipid-coated targeted microbubbles are used for ultrasound molecular imaging and locally enhanced drug delivery, with the binding efficacy being an important trait. The use of organic solvent in microbubble production makes the difference between a heterogeneous or homogeneous ligand distribution. This study demonstrates the effect of ligand distribution on the binding efficacy of phospholipid-coated ανβ3-targeted microbubbles in vitro using a monolayer of human umbilical-vein endothelial cells and in vivo using chicken embryos. Microbubbles with a homogeneous ligand distribution had a higher binding efficacy than those with a heterogeneous ligand distribution both in vitro and in vivo. In vitro, 1.55× more microbubbles with a homogeneous ligand distribution bound under static conditions, while this was 1.49× more under flow with 1.25 dyn/cm2, 1.56× more under flow with 2.22 dyn/cm2, and 1.25× more in vivo. The in vitro dissociation rate of bound microbubbles with homogeneous ligand distribution was lower at low shear stresses (1-5 dyn/cm2). The internalized depth of bound microbubbles was influenced by microbubble size, not by ligand distribution. In conclusion, for optimal binding the use of organic solvent in targeted microbubble production is preferable over directly dispersing phospholipids in aqueous medium.","Binding efficacy; Ligand distribution; Phospholipid-coated microbubbles; Targeted drug delivery; Ultrasound molecular imaging","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:01b88545-4021-4872-a97b-a2d90c8660eb","http://resolver.tudelft.nl/uuid:01b88545-4021-4872-a97b-a2d90c8660eb","Towards an integrated framework to measure smart city readiness: The case of iranian cities","Noori, Negar (Erasmus Universiteit Rotterdam); de Jong, Martin (Erasmus Universiteit Rotterdam; Fudan University); Hoppe, T. (TU Delft Organisation & Governance)","","2020","This paper introduces an indicator system to measure and assess smart city readiness. Analyzing smart city initiatives in Iran as case studies, the theoretical framework we present reflects on how cities explore the possibility of becoming smart, and prepare themselves to begin implementing the transition towards becoming a smart city. This theoretical framework is then applied to four Iranian cities aspiring to become smart and that already possess credible smart city brands. The findings reveal that the most significant difficulty in Iran is associated with the political context. The changing urban governance model is the most important factor in Iranian smart cities’ readiness. Utilization of open data policies and data sharing, as well as making reforms in government structures are all considered a sine qua non to gain momentum. Based on the results of our empirical analysis a Theory of Change is developed to address the cities’ technological, socio-economic, and political readiness vis-à-vis the desired transition. The framework for measuring smart city readiness and the Theory of Change provide practical guidelines to developing systematic roadmaps for developing and implementing smart city policies.","Iranian cities; Political readiness; Smart city; Social readiness; Technological readiness; Theory of change; Urban transition","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:0c290281-f932-4850-87b7-6266796f9093","http://resolver.tudelft.nl/uuid:0c290281-f932-4850-87b7-6266796f9093","Electroreduction of CO2/CO to C2Products: Process Modeling, Downstream Separation, System Integration, and Economic Analysis","Ramdin, M. (TU Delft Engineering Thermodynamics); De Mot, Bert (Universiteit Antwerpen); Morrison, A.R.T. (TU Delft Large Scale Energy Storage); Breugelmans, Tom (Universiteit Antwerpen); van den Broeke, L.J.P. (TU Delft Engineering Thermodynamics); Kortlever, R. (TU Delft Large Scale Energy Storage); de Jong, W. (TU Delft Large Scale Energy Storage); Moultos, O. (TU Delft Engineering Thermodynamics); Vlugt, T.J.H. (TU Delft Engineering Thermodynamics)","","2021","Direct electrochemical reduction of CO2 to C2 products such as ethylene is more efficient in alkaline media, but it suffers from parasitic loss of reactants due to (bi)carbonate formation. A two-step process where the CO2 is first electrochemically reduced to CO and subsequently converted to desired C2 products has the potential to overcome the limitations posed by direct CO2 electroreduction. In this study, we investigated the technical and economic feasibility of the direct and indirect CO2 conversion routes to C2 products. For the indirect route, CO2 to CO conversion in a high temperature solid oxide electrolysis cell (SOEC) or a low temperature electrolyzer has been considered. The product distribution, conversion, selectivities, current densities, and cell potentials are different for both CO2 conversion routes, which affects the downstream processing and the economics. A detailed process design and techno-economic analysis of both CO2 conversion pathways are presented, which includes CO2 capture, CO2 (and CO) conversion, CO2 (and CO) recycling, and product separation. Our economic analysis shows that both conversion routes are not profitable under the base case scenario, but the economics can be improved significantly by reducing the cell voltage, the capital cost of the electrolyzers, and the electricity price. For both routes, a cell voltage of 2.5 V, a capital cost of $10,000/m2, and an electricity price of <$20/MWh will yield a positive net present value and payback times of less than 15 years. Overall, the high temperature (SOEC-based) two-step conversion process has a greater potential for scale-up than the direct electrochemical conversion route. Strategies for integrating the electrochemical CO2/CO conversion process into the existing gas and oil infrastructure are outlined. Current barriers for industrialization of CO2 electrolyzers and possible solutions are discussed as well.","","en","journal article","","","","","","","","","","","Engineering Thermodynamics","","",""
"uuid:2879f424-be9e-4f1a-8103-3936dc22d5ca","http://resolver.tudelft.nl/uuid:2879f424-be9e-4f1a-8103-3936dc22d5ca","The Societal Readiness Thinking Tool: A Practical Resource for Maturing the Societal Readiness of Research Projects","Bernstein, Michael J. (AIT Austrian Institute of Technology; Arizona State University); Nielsen, Mathias Wullum (University of Copenhagen); Alnor, Emil (Aarhus University); Brasil, André (Universiteit Leiden); Birkving, Astrid Lykke (Aarhus University); Chan, Tung Tung (Universiteit Leiden); Griessler, Erich (Institute for Advanced Studies); de Jong, Stefan (Tilburg University; Private Bag X1); van de Klippe, Wouter (Universiteit Leiden); Meijer, Ingeborg (Universiteit Leiden); Yaghmaei, E. (TU Delft Ethics & Philosophy of Technology); Nicolaisen, Peter Busch (Aarhus University); Nieminen, Mika (VTT Technical Research Center of Finland); Novitzky, Peter (Wageningen University & Research); Mejlgaard, Niels (Aarhus University)","","2022","In this paper, we introduce the Societal Readiness (SR) Thinking Tool to aid researchers and innovators in developing research projects with greater responsiveness to societal values, needs, and expectations. The need for societally-focused approaches to research and innovation—complementary to Technology Readiness (TR) frameworks—is presented. Insights from responsible research and innovation (RRI) concepts and practice, organized across critical stages of project-life cycles are discussed with reference to the development of the SR Thinking Tool. The tool is designed to complement not only shortfalls in TR approaches, but also improve upon other efforts to integrate RRI, sustainability, and design thinking in research and innovation cycles. Operationalization and early-stage user tests of the Tool are reported, along with discussion of potential future iterations and applications.","Innovation; Research management; Responsible research and innovation; RRI; Societal Readiness; Technology Readiness Levels; Thinking Tool; TRL","en","journal article","","","","","","","","","","","Ethics & Philosophy of Technology","","",""
"uuid:89405cfc-ed92-4b6c-b78b-2d4d5be9ad41","http://resolver.tudelft.nl/uuid:89405cfc-ed92-4b6c-b78b-2d4d5be9ad41","How do political features influence the co-production of government projects? A case study of a medium-sized chinese city","Ma, W. (TU Delft Multi Actor Systems; Harbin Institute of Technology); Mu, Rui (Dalian University of Technology); de Jong, Martin (Erasmus Universiteit Rotterdam; Fudan University)","","2021","Co-production is a solution by which the government provides public services. Coproduction theory is built upon Western experience and currently focuses on the types of coproduction in different policy stages, the barriers and governance strategies for co-production. However, little attention is paid to how political background will influence the co-production process. To fill the gap, we analyzed a case of co-production that occurred in China, and we characterized the political background as consisting of three main political features: political mobility, central–local relations, and performance measurement. Based on an in-depth case study of a government project in a medium-sized Chinese city, the impact and the changes of political features affecting governmental projects in different co-production stages are analyzed and assessed. We find that political features play a critical role in the co-production of China’s large government projects and may separately and jointly affect co-production. Government performance measurement affects the co-design and co-implementation of projects. Political mobility and changes in local government and performance measurement also affect the co-implementation continuity of the project. Political focus affects the co-design of projects. Central-local relations influence the support from higher government and the actual practices of lower government in the co-implementation stage.","China; Co-design; Co-implementation; Co-production; Political features; Project management","en","journal article","","","","","","","","","","Multi Actor Systems","","","",""
"uuid:d5af800f-caab-4364-855d-c0ac57ace54c","http://resolver.tudelft.nl/uuid:d5af800f-caab-4364-855d-c0ac57ace54c","Exploiting nonlinear wave propagation to improve the precision of ultrasonic flow meters","Massaad Mouawad, J.M. (TU Delft ImPhys/Medical Imaging); van Neer, P.L.M.J. (TU Delft ImPhys/Medical Imaging; TNO); van Willigen, D.M. (TU Delft Electronic Instrumentation); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC)","","2021","Acoustic wave propagation in ultrasonic flow measurements is typically assumed to be linear and reciprocal. However, if the transmitting transducer generates a sufficiently high pressure, nonlinear wave propagation effects become significant. In flow measurements, this would translate into more information to estimate the flow and therefore a higher precision relative to the linear case. In this work, we investigate how the generated harmonics can be used to measure flow. Measurements in a custom-made flow loop and simulations using the Khokhlov–Zabolotskaya–Kuznetsov (KZK) equation will show that the second harmonic component provides similar transit time differences to those obtained from the fundamental component, their linear combination results in more precise flow measurements compared to the estimations with the fundamental component alone.","KZK equation; Nonlinear acoustics; Ultrasonic flow meter","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:bdc0c89f-ca60-41c0-9186-2c5e619e04a3","http://resolver.tudelft.nl/uuid:bdc0c89f-ca60-41c0-9186-2c5e619e04a3","SPECT/CT imaging of inflammation and calcification in human carotid atherosclerosis to identify the plaque at risk of rupture","Van der Heiden, K. (Erasmus MC); Barrett, H. E. (Erasmus MC); van Gaalen, K.C. (Erasmus MC); Krenning, B. J. (Erasmus MC); Beekman, F.J. (TU Delft RST/Biomedical Imaging; University Medical Center Utrecht; MILabs B.V.); Verhagen, H. J.M. (Erasmus MC); Norenberg, J. P. (University of New Mexico); de Jong, M. (Erasmus MC); Gijsen, F.J.H. (Erasmus MC)","","2021","Background: Calcification and inflammation are atherosclerotic plaque compositional biomarkers that have both been linked to stroke risk. The aim of this study was to evaluate their co-existing prevalence in human carotid plaques with respect to plaque phenotype to determine the value of hybrid imaging for the detection of these biomarkers. Methods: Human carotid plaque segments, obtained from endarterectomy, were incubated in [111In]In-DOTA-butylamino-NorBIRT ([111In]In-Danbirt), targeting Leukocyte Function-associated Antigen-1 (LFA-1) on leukocytes. By performing SPECT/CT, both inflammation from DANBIRT uptake and calcification from CT imaging were assessed. Plaque phenotype was classified using histology. Results: On a total plaque level, comparable levels of calcification volume existed with different degrees of inflammation and vice versa. On a segment level, an inverse relationship between calcification volume and inflammation was evident in highly calcified segments, which classify as fibrocalcific, stable plaque segments. In contrast, segments with little or no calcification presented with a moderate to high degree of inflammation, often coinciding with the more dangerous fibrous cap atheroma phenotype. Conclusion: Calcification imaging alone can only accurately identify highly calcified, stable, fibrocalcific plaques. To identify high-risk plaques, with little or no calcification, hybrid imaging of calcification and inflammation could provide diagnostic benefit.","calcification; human carotid plaque; inflammation; SPECT/CT; vulnerable plaque","en","journal article","","","","","","","","","","","RST/Biomedical Imaging","","",""
"uuid:5f80a91d-a821-48bc-b606-72df74651bfb","http://resolver.tudelft.nl/uuid:5f80a91d-a821-48bc-b606-72df74651bfb","Shadow-wall lithography of ballistic superconductor–semiconductor quantum devices","Heedt, S. (TU Delft BUS/Quantum Delft; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft; Microsoft Quantum Lab Delft); Quintero Perez, M. (TU Delft BUS/Quantum Delft; Microsoft Quantum Lab Delft); Borsoi, F. (TU Delft QCD/Veldhorst Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); van Loo, N. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Mazur, G.P. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Ammerlaan, M.L.I. (TU Delft ALG/General; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Li, K. (TU Delft BUS/Quantum Delft; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Korneychuk, S. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); van de Poll, M.A.Y. (TU Delft QCD/Vandersypen Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); de Jong, N. (TU Delft BUS/TNO STAFF; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft; TNO); Aseev, P. (TU Delft BUS/Quantum Delft; Microsoft Quantum Lab Delft); van Hoogdalem, K.A. (TU Delft BUS/Quantum Delft; Microsoft Quantum Lab Delft); Kouwenhoven, Leo P. (TU Delft QN/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft; Microsoft Quantum Lab Delft)","","2021","The realization of hybrid superconductor–semiconductor quantum devices, in particular a topological qubit, calls for advanced techniques to readily and reproducibly engineer induced superconductivity in semiconductor nanowires. Here, we introduce an on-chip fabrication paradigm based on shadow walls that offers substantial advances in device quality and reproducibility. It allows for the implementation of hybrid quantum devices and ultimately topological qubits while eliminating fabrication steps such as lithography and etching. This is critical to preserve the integrity and homogeneity of the fragile hybrid interfaces. The approach simplifies the reproducible fabrication of devices with a hard induced superconducting gap and ballistic normal-/superconductor junctions. Large gate-tunable supercurrents and high-order multiple Andreev reflections manifest the exceptional coherence of the resulting nanowire Josephson junctions. Our approach enables the realization of 3-terminal devices, where zero-bias conductance peaks emerge in a magnetic field concurrently at both boundaries of the one-dimensional hybrids.","","en","journal article","","","","","","","","","","","BUS/Quantum Delft","","",""
"uuid:4abc35e9-146f-4d46-91a6-4962af289c5e","http://resolver.tudelft.nl/uuid:4abc35e9-146f-4d46-91a6-4962af289c5e","Tapering of the interventricular septum can affect ultrasound shear wave elastography: An in vitro and in silico study","Sabbadini, A. (TU Delft ImPhys/Medical Imaging); Caenen, A.F.M. (Erasmus MC; Universiteit Gent); Keijzer, L.B.H. (Erasmus MC); van Neer, P.L.M.J. (TU Delft ImPhys/Medical Imaging; TNO); Vos, H.J. (TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC)","","2021","Shear wave elastography (SWE) has the potential to determine cardiac tissue stiffness from non-invasive shear wave speed measurements, important, e.g., for predicting heart failure. Previous studies showed that waves traveling in the interventricular septum (IVS) may display Lamb-like dispersive behaviour, introducing a thickness-frequency dependency in the wave speed. However, the IVS tapers across its length, which complicates wave speed estimation by introducing an additional variable to account for. The goal of this work is to assess the impact of tapering thickness on SWE. The investigation is performed by combining in vitro experiments with acoustic radiation force (ARF) and 2D finite element simulations, to isolate the effect of the tapering curve on ARF-induced and natural waves in the heart. The experiments show a 11% deceleration during propagation from the thick to the thin end of an IVS-mimicking tapered phantom plate. The numerical analysis shows that neglecting the thickness variation in the wavenumber-frequency domain can introduce errors of more than 30% in the estimation of the shear modulus, and that the exact tapering curve, rather than the overall thickness reduction, determines the dispersive behaviour of the wave. These results suggest that septal geometry should be accounted for when deriving cardiac stiffness with SWE.","","en","journal article","","","","","","","","2022-01-20","","","ImPhys/Medical Imaging","","",""
"uuid:43e92fb2-cf69-4e7c-9ecd-3cb6a6915e38","http://resolver.tudelft.nl/uuid:43e92fb2-cf69-4e7c-9ecd-3cb6a6915e38","Motion-compensated noninvasive periodontal health monitoring using handheld and motor-based photoacoustic-ultrasound imaging systems","Mozaffarzadeh, M. (TU Delft ImPhys/Medical Imaging); Moore, Colman (University of California); Golmoghani, Erfan Barzegar (Tarbiat Modares University); Mantri, Yash (University of California); Hariri, Ali (University of California); Jorns, Alec (University of California); Fu, Lei (University of California); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC)","","2021","Simultaneous visualization of the teeth and periodontium is of significant clinical interest for image-based monitoring of periodontal health. We recently reported the application of a dual-modality photoacoustic-ultrasound (PA-US) imaging system for resolving periodontal anatomy and periodontal pocket depths in humans. This work utilized a linear array transducer attached to a stepper motor to generate 3D images via maximum intensity projection. This prior work also used a medical head immobilizer to reduce artifacts during volume rendering caused by motion from the subject (e.g., breathing, minor head movements). However, this solution does not completely eliminate motion artifacts while also complicating the imaging procedure and causing patient discomfort. To address this issue, we report the implementation of an image registration technique to correctly align B-mode PA-US images and generate artifact-free 2D cross-sections. Application of the deshaking technique to PA phantoms revealed 80% similarity to the ground truth when shaking was intentionally applied during stepper motor scans. Images from handheld sweeps could also be deshaken using an LED PA-US scanner. In ex vivo porcine mandibles, pigmentation of the enamel was well-estimated within 0.1 mm error. The pocket depth measured in a healthy human subject was also in good agreement with our prior study. This report demonstrates that a modality-independent registration technique can be applied to clinically relevant PA-US scans of the periodontium to reduce operator burden of skill and subject discomfort while showing potential for handheld clinical periodontal imaging.","","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:6f99d20d-6647-4a16-9292-eba5098a901e","http://resolver.tudelft.nl/uuid:6f99d20d-6647-4a16-9292-eba5098a901e","The preparation of chicken ex ovo embryos and chorioallantoic membrane vessels as in vivo model for contrast-enhanced ultrasound imaging and microbubble-mediated drug delivery studies","Meijlink, Bram (Erasmus MC); Skachkov, Ilya (Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Kooiman, Klazina (Erasmus MC)","","2021","The chicken embryo and the blood-vessel rich chorioallantoic membrane (CAM) is a valuable in vivo model to investigate biomedical processes, new ultrasound pulsing schemes, or novel transducers for contrast-enhanced ultrasound imaging and microbubble-mediated drug delivery. The reasons for this are the accessibility of the embryo and vessel network of the CAM as well as the low costs of the model. An important step to get access to the embryo and CAM vessels is to take the egg content out of the eggshell. In this protocol, three methods for taking the content out of the eggshell between day 5 and 8 of incubation are described thus allowing the embryos to develop inside the eggshell up to these days. The described methods only require simple tools and equipment and yield a higher survival success rate of 90% for 5-day, 75% for 6-day, 50% for 7-day, and 60% for 8-day old incubated eggs in comparison to ex ovo cultured embryos (~50%). The protocol also describes how to inject cavitation nuclei, such as microbubbles, into the CAM vascular system, how to separate the membrane containing the embryo and CAM from the rest of the egg content for optically transparent studies, and how to use the chicken embryo and CAM in a variety of short-term ultrasound experiments. The in vivo chicken embryo and CAM model is extremely relevant to investigate novel imaging protocols, ultrasound contrast agents, and ultrasound pulsing schemes for contrast-enhanced ultrasound imaging, and to unravel the mechanisms of ultrasound-mediated drug delivery.","","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:e6aa1204-60c7-4cda-ad8c-3bcd553c0cd2","http://resolver.tudelft.nl/uuid:e6aa1204-60c7-4cda-ad8c-3bcd553c0cd2","Fragmentation of fuel pellets during transport via a belt conveyor: A design of experiment study","Gilvari, H. (TU Delft Large Scale Energy Storage); van Battum, Coen H.H. (Student TU Delft); Farnish, Richard (University of Greenwich); Pang, Y. (TU Delft Transport Engineering and Logistics); de Jong, W. (TU Delft Large Scale Energy Storage); Schott, D.L. (TU Delft Transport Engineering and Logistics)","","2022","This work investigates the proportion of generated fines in a pilot-scale experiment using a belt conveyor and commercial fuel pellets. For this, a belt conveyor with a length of 3.1 m was used and operated at varying conditions: speeds, percentages of material loading on the belt, two combinations of the inclination angle of the belt and the falling height, and a different number of handling steps. We considered a design of experiments approach based on response surface methodology to investigate the effect of different conditions on the potential of fines generation. Moreover, a comparison between the results of the belt conveyor and three common benchmark experimental approaches (tumbling box, rotary impact tester, and mechanical compression test) was made. Results show that the number of handling steps and the combined effect of drop height and inclination angle directly affected the fines generation. However, the tested belt speed range and the level of loading were of lower significance. A polynomial quadratic model was derived based on the regression analysis and showed a high accuracy to predict the proportion of fines. Moreover, the tumbling box method showed good potential to predict the proportion of fines in a belt conveyor when transported several times.","Belt conveyor; Box–Behnken design; Breakage; Design of experiment; Fuel pellets; Transport","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:2e65bdbb-8790-4f79-8192-25f25a202c78","http://resolver.tudelft.nl/uuid:2e65bdbb-8790-4f79-8192-25f25a202c78","Spatiotemporal Distribution of Nanodroplet Vaporization in a Proton Beam Using Real-Time Ultrasound Imaging for Range Verification","Collado Lara, G. (Erasmus MC); Heymans, Sophie V. (Erasmus MC; Katholieke Universiteit Leuven); Rovituso, M. (Holland Particle Therapy Centre); Carlier, Bram (Katholieke Universiteit Leuven); Toumia, Yosra (University of Rome Tor Vergata); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Biomedical Engineering; Erasmus MC); Vos, H.J. (TU Delft ImPhys/Medical Imaging; Biomedical Engineering; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Biomedical Engineering; Erasmus MC); Daeichin, V. (TU Delft ImPhys/Medical Imaging)","","2021","The potential of proton therapy to improve the conformity of the delivered dose to the tumor volume is currently limited by range uncertainties. Injectable superheated nanodroplets have recently been proposed for ultrasound-based in vivo range verification, as these vaporize into echogenic microbubbles on proton irradiation. In previous studies, offline ultrasound images of phantoms with dispersed nanodroplets were acquired after irradiation, relating the induced vaporization profiles to the proton range. However, the aforementioned method did not enable the counting of individual vaporization events, and offline imaging cannot provide real-time feedback. In this study, we overcame these limitations using high-frame-rate ultrasound imaging with a linear array during proton irradiation of phantoms with dispersed perfluorobutane nanodroplets at 37°C and 50°C. Differential image analysis of subsequent frames allowed us to count individual vaporization events and to localize them with a resolution beyond the ultrasound diffraction limit, enabling spatial and temporal quantification of the interaction between ionizing radiation and nanodroplets. Vaporization maps were found to accurately correlate with the stopping distribution of protons (at 50°C) or secondary particles (at both temperatures). Furthermore, a linear relationship between the vaporization count and the number of incoming protons was observed. These results indicate the potential of real-time high-frame-rate contrast-enhanced ultrasound imaging for proton range verification and dosimetry.","Dosimetry; Nanodroplets; Proton therapy; Range verification; Ultrasound","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:72f7f05f-bb74-44d2-b858-05cc16731909","http://resolver.tudelft.nl/uuid:72f7f05f-bb74-44d2-b858-05cc16731909","Directional Excitation of a High-Density Magnon Gas Using Coherently Driven Spin Waves","Simon, B.G. (TU Delft QN/vanderSarlab; TU Delft QN/Quantum Nanoscience; Kavli institute of nanoscience Delft); Kurdi, S. (TU Delft QN/vanderSarlab; TU Delft QN/Quantum Nanoscience; Kavli institute of nanoscience Delft); La, Helena (External organisation); Bertelli, I. (TU Delft QN/vanderSarlab; TU Delft QN/Quantum Nanoscience; Kavli institute of nanoscience Delft; Universiteit Leiden); Carmiggelt, J.J. (TU Delft QN/vanderSarlab; TU Delft QN/Quantum Nanoscience; Kavli institute of nanoscience Delft); Ruf, M.T. (TU Delft QID/Hanson Lab); de Jong, N. (TU Delft BUS/TNO STAFF; TU Delft QuTech Advanced Research Centre; TNO); van den Berg, J.H. (TU Delft Business Development; TU Delft QuTech Advanced Research Centre; TNO); Katan, A.J. (TU Delft QN/Afdelingsbureau; TU Delft QN/Quantum Nanoscience; Kavli institute of nanoscience Delft); van der Sar, T. (TU Delft QN/vanderSarlab; TU Delft QN/Quantum Nanoscience; Kavli institute of nanoscience Delft)","","2021","Controlling magnon densities in magnetic materials enables driving spin transport in magnonic devices. We demonstrate the creation of large, out-of-equilibrium magnon densities in a thin-film magnetic insulator via microwave excitation of coherent spin waves and subsequent multimagnon scattering. We image both the coherent spin waves and the resulting incoherent magnon gas using scanning-probe magnetometry based on electron spins in diamond. We find that the gas extends unidirectionally over hundreds of micrometers from the excitation stripline. Surprisingly, the gas density far exceeds that expected for a boson system following a Bose-Einstein distribution with a maximum value of the chemical potential. We characterize the momentum distribution of the gas by measuring the nanoscale spatial decay of the magnetic stray fields. Our results show that driving coherent spin waves leads to a strong out-of-equilibrium occupation of the spin-wave band, opening new possibilities for controlling spin transport and magnetic dynamics in target directions.","Magnon gas; Nitrogen-vacancy centers; Scanning-probe magnetometry; Spin relaxometry; Spin waves; Yttrium iron garnet","en","journal article","","","","","","","","","","QN/Quantum Nanoscience","QN/vanderSarlab","","",""
"uuid:964391de-c6cf-4c86-8726-7f0e4a03dc85","http://resolver.tudelft.nl/uuid:964391de-c6cf-4c86-8726-7f0e4a03dc85","Spiderweb Nanomechanical Resonators via Bayesian Optimization: Inspired by Nature and Guided by Machine Learning","Shin, D. (TU Delft Team Georgy Filonenko); Cupertino, A. (TU Delft Dynamics of Micro and Nano Systems); de Jong, M.H.J. (TU Delft QN/Groeblacher Lab; TU Delft Dynamics of Micro and Nano Systems); Steeneken, P.G. (TU Delft Dynamics of Micro and Nano Systems; TU Delft QN/Steeneken Lab); Bessa, M.A. (TU Delft Team Georgy Filonenko); Norte, R.A. (TU Delft QN/Groeblacher Lab; TU Delft Dynamics of Micro and Nano Systems)","","2021","From ultrasensitive detectors of fundamental forces to quantum networks and sensors, mechanical resonators are enabling next-generation technologies to operate in room-temperature environments. Currently, silicon nitride nanoresonators stand as a leading microchip platform in these advances by allowing for mechanical resonators whose motion is remarkably isolated from ambient thermal noise. However, to date, human intuition has remained the driving force behind design processes. Here, inspired by nature and guided by machine learning, a spiderweb nanomechanical resonator is developed that exhibits vibration modes, which are isolated from ambient thermal environments via a novel “torsional soft-clamping” mechanism discovered by the data-driven optimization algorithm. This bioinspired resonator is then fabricated, experimentally confirming a new paradigm in mechanics with quality factors above 1 billion in room-temperature environments. In contrast to other state-of-the-art resonators, this milestone is achieved with a compact design that does not require sub-micrometer lithographic features or complex phononic bandgaps, making it significantly easier and cheaper to manufacture at large scales. These results demonstrate the ability of machine learning to work in tandem with human intuition to augment creative possibilities and uncover new strategies in computing and nanotechnology.","bioinspiration; data-driven optimization; high quality factor; room-temperature nanoresonators; torsional soft clamping","en","journal article","","","","","","","","","","","Team Georgy Filonenko","","",""
"uuid:78acfc25-f9d8-4c42-b962-047f3c73e634","http://resolver.tudelft.nl/uuid:78acfc25-f9d8-4c42-b962-047f3c73e634","Gasification of woody biomass in a novel indirectly heated bubbling fluidized bed steam reformer","Tsekos, C. (TU Delft Large Scale Energy Storage); Del Grosso, M. (TU Delft Large Scale Energy Storage); de Jong, W. (TU Delft Large Scale Energy Storage; Rijksuniversiteit Groningen)","","2021","Within this work, a novel 50 kWth indirectly heated bubbling fluidized bed steam reformer (IHBFBSR) is presented, along with its commissioning experiments. In the IHBFBSR, heat is provided through two radiant tube natural gas burners in the bed and the freeboard area. The aim of this innovative design is sufficient heat provision for biomass steam reforming and cracking reactions and heat loss reduction, thus allowing the possibility of scaling-up to an industrial level. Experiments were performed with two woody biomass feedstocks and two bed material particle sizes under different operating conditions (steam to biomass ratio, lambda, temperature), in order to identify the setup's main characteristics. Product gas composition and quality, as well as the cold gas efficiency of the IHBFBSR were in reasonable agreement to similar systems, however carbon conversion prediction needs further improvement. H2 production and tar removal are favoured by small bed material particle sizes as well as by char accumulation in the bed area. Furthermore, air injection above the bed led to improved H2/CO ratios and lower tar yields compared to when air is used as a fluidization agent. Overall, it was shown that the IHBFBSR technology constitutes a promising development in the field of biomass allothermal gasification.","Allothermal gasification; Biomass; Steam reforming; Synthesis gas","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:3b7c4bad-cefd-4d6c-9f4f-0e7f765e942c","http://resolver.tudelft.nl/uuid:3b7c4bad-cefd-4d6c-9f4f-0e7f765e942c","Vancomycin-decorated microbubbles as a theranostic agent for Staphylococcus aureus biofilms","Kouijzer, Joop J.P. (Erasmus MC); Lattwein, Kirby R. (Erasmus MC); Beekers, Inés (Erasmus MC); Langeveld, Simone A.G. (Erasmus MC); Leon-Grooters, Mariël (Erasmus MC); Strub, Jean Marc (University of Strasbourg); Oliva, Estefania (University of Strasbourg); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Medical Imaging; Erasmus MC)","","2021","Bacterial biofilms are a huge burden on our healthcare systems worldwide. The lack of specificity in diagnostic and treatment possibilities result in difficult-to-treat and persistent infections. The aim of this in vitro study was to investigate if microbubbles targeted specifically to bacteria in biofilms could be used both for diagnosis as well for sonobactericide treatment and demonstrate their theranostic potential for biofilm infection management. The antibiotic vancomycin was chemically coupled to the lipid shell of microbubbles and validated using mass spectrometry and high-axial resolution 4Pi confocal microscopy. Theranostic proof-of-principle was investigated by demonstrating the specific binding of vancomycin-decorated microbubbles (vMB) to statically and flow grown Staphylococcus aureus (S. aureus) biofilms under increasing shear stress flow conditions (0–12 dyn/cm2), as well as confirmation of microbubble oscillation and biofilm disruption upon ultrasound exposure (2 MHz, 250 kPa, and 5,000 or 10,000 cycles) during flow shear stress of 5 dyn/cm2 using time-lapse confocal microscopy combined with the Brandaris 128 ultra-high-speed camera. Vancomycin was successfully incorporated into the microbubble lipid shell. vMB bound significantly more often than control microbubbles to biofilms, also in the presence of free vancomycin (up to 1000 µg/mL) and remained bound under increasing shear stress flow conditions (up to 12 dyn/cm2). Upon ultrasound insonification biofilm area was reduced of up to 28%, as confirmed by confocal microscopy. Our results confirm the successful production of vMB and support their potential as a new theranostic tool for S. aureus biofilm infections by allowing for specific bacterial detection and biofilm disruption.","Biofilm; Sonobactericide; Targeted microbubble; Theranostic; Ultrasound; Vancomycin","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:ef50498a-5408-4808-846f-0ad087a68eb7","http://resolver.tudelft.nl/uuid:ef50498a-5408-4808-846f-0ad087a68eb7","Two phase modelling of Geldart B particles in a novel indirectly heated bubbling fluidized bed biomass steam reformer","Tsekos, C. (TU Delft Large Scale Energy Storage); de Voogt, D.; de Jong, W. (TU Delft Large Scale Energy Storage); Padding, J.T. (TU Delft Complex Fluid Processing)","","2022","This work focuses on the numerical modelling and experimental validation of the hydrodynamic behaviour of a novel 50 kWth indirectly heated bubbling fluidized bed steam reformer. The hydrodynamic behaviour of fluidized beds with immersed vertical tubes and complex fluidized bed geometries in general have not been thoroughly investigated in terms of numerical modelling coupled with experimental validation for pilot scale reactors. Therefore, the present study contributes to the fluidized bed hydrodynamics numerical modelling field, while investigating a novel reactor concept. Simulations were performed employing the Two-Fluid Model approach, using the Kinetic Theory of Granular Flows (KTGF) and the adjusted Syamlal O'Brien drag model. The reactor's hydrodynamic behaviour was simulated successfully, as showcased by a comparison of global hydrodynamic metrics (bed height, pressure drop) between computational and experimental results. Simulations were performed with and without considering an additional nitrogen gas feed on the side of the reactor (feeding system pressurization). Overall, for both cases, for realistic values of the particle restitution coefficient channelling of the gas flow near the reactor walls was observed. Larger bubbles appeared to be forming near the outer wall of the reactor for the no side-flow simulations. The opposite behaviour was encountered for the side-flow simulations due to stream-like behaviour of the side-flow moving up against the reactor's outer wall. The choice to limit the simulations to a 72° symmetry domain was validated, indicating the possibility of further reduction. Finally, it was argued that increasing the reactor's diameter could potentially lead to a reduction of the observed channelling of the fluidization media and improve the mixing achieved in the reactor and thus the conversion efficiency of the IHBFBSR during gasification applications.","Allothermal; CFD; Fluidized bed; Gasification; Non-standard geometry; TFM","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:e368932b-0dd6-4c2e-adcb-4aeea910a298","http://resolver.tudelft.nl/uuid:e368932b-0dd6-4c2e-adcb-4aeea910a298","Pure methane from CO2 hydrogenation using a sorption enhanced process with catalyst/zeolite bifunctional materials","Wei, L. (TU Delft Large Scale Energy Storage); Azad, Hamza (Student TU Delft); Haije, W.G. (TU Delft ChemE/Materials for Energy Conversion and Storage); Grenman, L.O.H. (Åbo Akademi University); de Jong, W. (TU Delft Large Scale Energy Storage)","","2021","Methanation is a potential large-scale option for CO2 utilization, and it is one of the solutions for decreasing carbon emission and production of synthetic green fuels. However, the CO2 conversion is limited by thermodynamics in conventional reaction conditions. However, around 100 % conversion can be obtained using sorption enhanced CO2 methanation according to Le Chatelier's principle, where water is removed during the reaction using zeolite as a sorbent. In this work 5%Ni5A, 5%Ni13X, 5%NiL and 5%Ni2.5%Ce13X bifunctional materials with both catalytic and water adsorption properties were tested in a fixed bed reactor. The overall performance of the bifunctional materials decreased on going from 5%Ni2.5%Ce13X, 5%Ni13X, 5%Ni5A, to 5%NiL. The CO2 conversion and CH4 selectivity were approaching 100 % during prolonged stability testing in a 100 reactive adsorption – desorption cycles test for 5%Ni2.5%Ce13X, and only a slight decrease of the water uptake capacity was observed.","Bifunctional materials; CO methanation; Sorption enhanced; Water removal; Zeolites","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:ab3ebe0a-d9dc-4299-839f-449f3e973eab","http://resolver.tudelft.nl/uuid:ab3ebe0a-d9dc-4299-839f-449f3e973eab","Bibliometric dataset (1990–2019) concerning 35 city labels dealing with sustainable urbanism","Joss, Simon (University of Glasgow); Schraven, D.F.J. (TU Delft Integral Design & Management); de Jong, W.M. (TU Delft Organisation & Governance; Erasmus Universiteit Rotterdam)","","2022","This data article presents a tripartite dataset that formed the empirical basis for a comprehensive bibliometric analysis of the use of city labels denoting sustainable urbanism in the scientific literature (Schraven, 2021). The tripartite dataset was generated using the abstract and citation database Scopus (Elsevier). Dataset A lists 148 city labels denoting different approaches to urban planning and development. It was used to select 35 city labels that specifically address sustainable urbanism (‘sustainable city’, ‘smart city’, ‘compact city’ etc.). Dataset B references 11,337 journal and review articles spanning the period 1990–2019. All retrieved articles contain at least one of the 35 city labels in the title, abstract, and author keywords. This database was used to calculate the frequency of the selected city labels across time, and to analyze the co-occurrences of city labels. It was further used to calculate the future trajectory of scientific outputs using the Logistic Growth Model (LGM). Dataset C entails 22,820 author keywords extracted from across the 11,337 articles. This was used to analyze the co-occurrences of keywords with city labels. The data article describes the methods of data collection and curation, the analysis performed, and the potential for reusing the data for further research. The comprehensiveness of the bibliometric corpus – spanning three decades and 35 city labels – lends itself to further investigation of how sustainable urban development has evolved as a topic in the scientific literature since the 1990s. Furthermore, the robust methodology developed could be adapted to other scientific repositories and, indeed, other research problems and questions.","Bibliometrics; City labels; Scientometrics; SDGs; Smart city; Sustainable city; Urban development; Urban futures","en","journal article","","","","","","","","","","","Integral Design & Management","","",""
"uuid:30749ebd-d361-437c-8095-0e1cd3c9e406","http://resolver.tudelft.nl/uuid:30749ebd-d361-437c-8095-0e1cd3c9e406","Error analysis and reliability of zero-order Lamb mode inversion for waveguide characterization","Sabbadini, A. (TU Delft Human-Robot Interaction; TU Delft ImPhys/Medical Imaging); Massaad Mouawad, J.M. (TU Delft ImPhys/Medical Imaging); van Neer, P.L.M.J. (TU Delft ImPhys/Medical Imaging; TU Delft BUS/TNO STAFF; TNO); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC)","","2022","In recent years, several fitting techniques have been presented to reconstruct the parameters of a plate from its Lamb wave dispersion curves. Published studies show that these techniques can yield high accuracy results and have the potential of reconstructing several parameters at once. The precision with which parameters can be reconstructed by inverting Lamb wave dispersion curves, however, remains an open question of fundamental importance to many applications. In this work, we introduce a method of analyzing dispersion curves that yields quantitative information on the precision with which the parameters can be extracted. In our method, rather than employing error minimization algorithms, we compare a target dispersion curve to a database of theoretical ones that covers a given parameter space. By calculating a measure of dissimilarity (error) for every point in the parameter space, we reconstruct the distribution of the error in that space, beside the location of its minimum. We then introduce dimensionless quantities that describe the distribution of this error, thus yielding information about the spread of similar curves in the parameter space. We demonstrate our approach by considering both idealized and realistic scenarios, analyzing the dispersion curves obtained numerically for a plate and experimentally for a pipe. Our results show that the precision with which each parameter is reconstructed depends on the mode used, as well as the frequency range in which it is considered.","Lamb wave; Multi-parameter inversion; Non-destructive testing; Sensitivity","en","journal article","","","","","","","","","","","Human-Robot Interaction","","",""
"uuid:1b4f17fb-d41a-47fe-ae96-23d0a7d9127f","http://resolver.tudelft.nl/uuid:1b4f17fb-d41a-47fe-ae96-23d0a7d9127f","A spatial and temporal characterisation of single proton acoustic waves in proton beam cancer therapy","Deurvorst, F.R. (TU Delft ImPhys/Medical Imaging); Collado Lara, G. (Erasmus MC); Matalliotakis, A. (TU Delft ImPhys/Medical Imaging); Vos, H.J. (Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging); Daeichin, V. (TU Delft ImPhys/Medical Imaging); Verweij, M.D. (TU Delft ImPhys/Medical Imaging)","","2022","An in vivo range verification technology for proton beam cancer therapy, preferably in real-time and with submillimeter resolution, is desired to reduce the present uncertainty in dose localization. Acoustical imaging technologies exploiting possible local interactions between protons and microbubbles or nanodroplets might be an interesting option. Unfortunately, a theoretical model capable of characterising the acoustical field generated by an individual proton on nanometer and micrometer scales is still missing. In this work, such a model is presented. The proton acoustic field is generated by the adiabatic expansion of a region that is locally heated by a passing proton. To model the proton heat deposition, secondary electron production due to protons has been quantified using a semi-empirical model based on Rutherford's scattering theory, which reproduces experimentally obtained electronic stopping power values for protons in water within 10% over the full energy range. The electrons transfer energy into heat via electron-phonon coupling to atoms along the proton track. The resulting temperature increase is calculated using an inelastic thermal spike model. Heat deposition can be regarded as instantaneous, thus, stress confinement is ensured and acoustical initial conditions are set. The resulting thermoacoustic field in the nanometer and micrometer range from the single proton track is computed by solving the thermoacoustic wave equation using k-space Green's functions, yielding the characteristic amplitudes and frequencies present in the acoustic signal generated by a single proton in an aqueous medium. Wavefield expansion and asymptotic approximations are used to extend the spatial and temporal ranges of the proton acoustic field.","","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:0ed74d6c-6c05-4c3f-95c5-5c08b20e3fb9","http://resolver.tudelft.nl/uuid:0ed74d6c-6c05-4c3f-95c5-5c08b20e3fb9","Radio-Frequency C - V Measurements with Subattofarad Sensitivity","Malinowski, F.K. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Han, L. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); de Jong, D. (TU Delft BUS/Quantum Delft; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Wang, Ji Yin (Kavli institute of nanoscience Delft; Student TU Delft); Prosko, C.G. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre); Krogstrup, Peter (University of Copenhagen); Bakkers, Erik P.A.M. (Eindhoven University of Technology); Kouwenhoven, Leo P. (TU Delft QN/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Koski, Jonne V. (Microsoft Quantum Lab Delft)","","2022","We demonstrate the use of radio-frequency (rf) resonators to measure the capacitance of nanoscale semiconducting devices in field-effect transistor configurations. The rf resonator is attached to the gate or the lead of the device. Consequently, tuning the carrier density in the conducting channel of the device affects the resonance frequency, quantitatively reflecting its capacitance. We test the measurement method on InSb and InAs nanowires at dilution-refrigerator temperatures. The measured capacitances are consistent with those inferred from the periodicity of the Coulomb blockade of quantum dots realized in the same devices. In an implementation of the resonator using an off-chip superconducting spiral inductor we find the measurement sensitivity values reaching down to 75zF/Hz at 1 kHz measurement bandwidth, and noise down to 0.45 aF at 1 Hz bandwidth. We estimate the sensitivity of the method for a number of other implementations. In particular, we predict a typical sensitivity of about 40zF/Hz at room temperature with a resonator composed of off-the-shelf components. Of several proposed applications, we demonstrate two: the capacitance measurement of several identical 80-nm-wide gates with a single resonator, and the field-effect mobility measurement of an individual nanowire with the gate capacitance measured in situ.","","en","journal article","","","","","","","","","","","QRD/Kouwenhoven Lab","","",""
"uuid:61d37edb-3880-4b1e-b7f0-97aa5ebed8d2","http://resolver.tudelft.nl/uuid:61d37edb-3880-4b1e-b7f0-97aa5ebed8d2","Surface Coverage as an Important Parameter for Predicting Selectivity Trends in Electrochemical CO2 Reduction","Morrison, A.R.T. (TU Delft Large Scale Energy Storage); Ramdin, M. (TU Delft Engineering Thermodynamics); van den Broeke, L.J.P. (TU Delft Engineering Thermodynamics); de Jong, W. (TU Delft Large Scale Energy Storage); Vlugt, T.J.H. (TU Delft Process and Energy); Kortlever, R. (TU Delft Large Scale Energy Storage)","","2022","The electrochemical CO2 reduction reaction (CO2RR) is important for a sustainable future. Key insights into the reaction pathways have been obtained by density functional theory (DFT) analysis, but so far, DFT has been unable to give an overall understanding of selectivity trends without important caveats. We show that an unconsidered parameter in DFT models of electrocatalysts-the surface coverage of reacting species-is crucial for understanding the CO2RR selectivities for different surfaces. Surface coverage is a parameter that must be assumed in most DFT studies of CO2RR electrocatalysts, but so far, only the coverage of nonreacting adsorbates has been treated. Explicitly treating the surface coverage of reacting adsorbates allows for an investigation that can more closely mimic operating conditions. Furthermore, and of more immediate importance, the use of surface coverage-dependent adsorption energies allows for the extraction of ratios of adsorption energies of CO2RR intermediates (COOHads and HCOOads) that are shown to be predictive of selectivity and are not susceptible to systematic errors. This approach allows for categorization of the selectivity of several monometallic catalysts (Pt, Pd, Au, Ag, Zn, Cu, Rh, W, Pb, Sn, In, Cd, and Tl), even problematic ones such as Ag or Zn, and does so by only considering the adsorption energies of known intermediates. The selectivity of the further reduction of COOHads can now be explained by a preference for Tafel or Heyrovsky reactions, recontextualizing the nature of selectivity of some catalysts. In summary, this work resolves differences between DFT and experimental studies of the CO2RR and underlines the importance of surface coverage.","Adsorption; Catalysts; Energy; Materials; Selectivity","en","journal article","","","","","","","","","","Process and Energy","Large Scale Energy Storage","","",""
"uuid:83876e92-7645-4b21-ad0b-f5b793cf830b","http://resolver.tudelft.nl/uuid:83876e92-7645-4b21-ad0b-f5b793cf830b","Time-resolved absolute radius estimation of vibrating contrast microbubbles using an acoustical camera","Spiekhout, Sander (Erasmus MC); Voorneveld, J.D. (Erasmus MC); Van Elburg, Benjamin (University of Twente); Renaud, G.G.J. (TU Delft ImPhys/Medical Imaging); Segers, Tim (University of Twente); Lajoinie, Guillaume P.R. (University of Twente); Versluis, Michel (University of Twente); Verweij, M.D. (TU Delft ImPhys/Medical Imaging); de Jong, N. (TU Delft ImPhys/Medical Imaging); Bosch, Johannes G. (Erasmus MC)","","2022","Ultrasound (US) contrast agents consist of microbubbles ranging from 1 to 10 μm in size. The acoustical response of individual microbubbles can be studied with high-frame-rate optics or an ""acoustical camera""(AC). The AC measures the relative microbubble oscillation while the optical camera measures the absolute oscillation. In this article, the capabilities of the AC are extended to measure the absolute oscillations. In the AC setup, microbubbles are insonified with a high- (25 MHz) and low-frequency US wave (1-2.5 MHz). Other than the amplitude modulation (AM) from the relative size change of the microbubble (employed in Renaud, Bosch, van der Steen, and de Jong (2012a). ""An 'acoustical camera' for in vitro characterization of contrast agent microbubble vibrations,""Appl. Phys. Lett. 100(10), 101911, the high-frequency response from individual vibrating microbubbles contains a phase modulation (PM) from the microbubble wall displacement, which is the extension described here. The ratio of PM and AM is used to determine the absolute radius, R0. To test this sizing, the size distributions of two monodisperse microbubble populations (R 0 = 2.1 and 3.5 μm) acquired with the AC were matched to the distribution acquired with a Coulter counter. As a result of measuring the absolute size of the microbubbles, this ""extended AC""can capture the full radial dynamics of single freely floating microbubbles with a throughput of hundreds of microbubbles per hour.","","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:c345b0ef-d8cc-43d1-b1ff-ea90eaea15b8","http://resolver.tudelft.nl/uuid:c345b0ef-d8cc-43d1-b1ff-ea90eaea15b8","Influence of indirectly heated steam-blown gasification process conditions on biochar physico-chemical properties","Del Grosso, M. (TU Delft Large Scale Energy Storage); Cutz, L. (TU Delft Large Scale Energy Storage); Tiringer, U. (TU Delft Team Peyman Taheri); Tsekos, C. (TU Delft Large Scale Energy Storage); Taheri, P. (TU Delft Team Peyman Taheri); de Jong, W. (TU Delft Large Scale Energy Storage)","","2022","Our work provides a thorough characterization of different biochars produced by a novel 50 kWth Indirectly Heated Bubbling Fluidized Bed Steam Reformer. This study investigates the effect of temperature and gasification agent on the physico-chemical properties of biochars. We combined macro, micro and nano characterization techniques to provide a clear picture of the biochar characteristics, surface functionality and its “inert” nature toward potential applications. Our results demonstrate that indirect gasification is capable of producing carbon-rich biochars (> 92%) with increased porosity (89–198 cm3.g−1), high heating value (28–31 MJ.kg−1 a.r.) and aromaticity compared to the parent biomass. All biochars have lower O/C (0.02–0.04) and H/C atomic ratios (0.09–0.19), similar to anthracite. For the range of tested gasification conditions, air/steam gasification at an equivalence ratio of 0.20 and steam-to-biomass ratio of 1.2 provides the highest biochar yield (7.3%), while maintaining syngas composition optimal. On the other hand, air gasification produces biochars with relatively high content of inorganic elements. Indirectly heated biochars are compliant with the European Biochar Certificate regarding the carbon content, O/C ratio, H/C ratio. Our biochars may provide an improvement in agricultural yield and CO2 adsorption, especially those produced under air/steam gasification conditions. Our novel indirect design not only constitutes a promising development in the field of biomass allothermal gasification but also can help improving gasification circularity through the production of high quality biochar.","Biochar; Characterization techniques; Gasification; Surface Analysis","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:90cdbd78-d2cb-451e-8b6d-58bbccae8cb6","http://resolver.tudelft.nl/uuid:90cdbd78-d2cb-451e-8b6d-58bbccae8cb6","Internalization of targeted microbubbles by endothelial cells and drug delivery by pores and tunnels","Beekers, Inés (Erasmus MC; Ortec B.V.); Langeveld, Simone A.G. (Erasmus MC); Meijlink, Bram (Erasmus MC); van der Steen, A.F.W. (Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Kooiman, Klazina (Erasmus MC)","","2022","Ultrasound insonification of microbubbles can locally enhance drug delivery by increasing the cell membrane permeability. To aid development of a safe and effective therapeutic microbubble, more insight into the microbubble-cell interaction is needed. In this in vitro study we aimed to investigate the initial 3D morphology of the endothelial cell membrane adjacent to individual microbubbles (n = 301), determine whether this morphology was affected upon binding and by the type of ligand on the microbubble, and study its influence on microbubble oscillation and the drug delivery outcome. High-resolution 3D confocal microscopy revealed that targeted microbubbles were internalized by endothelial cells, while this was not the case for non-targeted or IgG1-κ control microbubbles. The extent of internalization was ligand-dependent, since αvβ3-targeted microbubbles were significantly more internalized than CD31-targeted microbubbles. Ultra-high-speed imaging (~17 Mfps) in combination with high-resolution confocal microscopy (n = 246) showed that microbubble internalization resulted in a damped microbubble oscillation upon ultrasound insonification (2 MHz, 200 kPa peak negative pressure, 10 cycles). Despite damped oscillation, the cell's susceptibility to sonoporation (as indicated by PI uptake) was increased for internalized microbubbles. Monitoring cell membrane integrity (n = 230) showed the formation of either a pore, for intracellular delivery, or a tunnel (i.e. transcellular perforation), for transcellular delivery. Internalized microbubbles caused fewer transcellular perforations and smaller pore areas than non-internalized microbubbles. In conclusion, studying microbubble-mediated drug delivery using a state-of-the-art imaging system revealed receptor-mediated microbubble internalization and its effect on microbubble oscillation and resulting membrane perforation by pores and tunnels.","Drug delivery; Microbubbles; Sonoporation; Transcellular perforation; Ultrasound","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:1e638e4c-ce53-42bb-95bb-fe5367838358","http://resolver.tudelft.nl/uuid:1e638e4c-ce53-42bb-95bb-fe5367838358","Spatial variability of leachate tables, leachate composition and hydraulic conductivity in a landfill stabilized by in-situ aeration","Gebert, J. (TU Delft Geo-engineering); de Jong, T. (TU Delft Geo-engineering); Meza Ramos, P.N. (TU Delft Geo-engineering); Rees-White, T. (TU Delft Geo-engineering; University of Southampton); Beaven, R.P. (University of Southampton); Lammen, J.K. (Afvalzorg - Sustainable Development, Assendelft)","","2022","Within the framework of the Dutch sustainable landfill project iDS, four compartments of the Dutch landfill Braambergen have been treated by in-situ aeration since 2017. The aeration infrastructure comprises 230 wells with a spacing of 15 to 20 m, distrib-uted over an area of around 10 ha, intercepting a waste body of 1.2 × 106 t of contam-inated soils, soil treatment residues, bottom ashes and construction and demolition waste. The wells, used in an alternating fashion for air injection and gas extraction, can also be used to monitor water tables within the waste body. In order to describe the spatial variability of waste hydraulics, design a larger scale leachate pumping test and, eventually, support model predictions of the site’s water balance and emission potential, analyses of leachate composition and pumping tests on individual wells have been conducted. The spatial variability of leachate quality and water tables is very high with no geospatial relationship between the sampling points. Each sampling point is representative of itself only. Large differences prevail not only between and across the compartments, but also between directly neighbouring wells. Both the small scale differences in leachate tables as well as in leachate quality indicate a spatial pattern of zones with low horizontal connectivity within the waste body. Recovery rates of drawdown in the wells yielded preliminary estimates of horizontal waste hydraulic conductivity in the order of 1×10-7 to 6×10-4 m/s.","Emission potential; Hydraulic conductivity; Leachate composition; Leachate tables; Waste hydrology","en","journal article","","","","","","","","","","","Geo-engineering","","",""
"uuid:f8da9624-5a3b-43c4-bd0c-be30fe168ea9","http://resolver.tudelft.nl/uuid:f8da9624-5a3b-43c4-bd0c-be30fe168ea9","Multi-angle data acquisition to compensate transducer finite size in photoacoustic tomography","Hakakzadeh, Soheil (Sharif University of Technology); Mozaffarzadeh, M. (TU Delft ImPhys/Medical Imaging); Mostafavi, S.. (Sharif University of Technology); Kavehvash, Zahra (Sharif University of Technology); Rajendran, Praveenbalaji (Nanyang Technological University); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Pramanik, Manojit (Nanyang Technological University)","","2022","In photoacoustic tomography (PAT) systems, the tangential resolution decreases due to the finite size of the transducer as the off-center distance increases. To address this problem, we propose a multi-angle detection approach in which the transducer used for data acquisition rotates around its center (with specific angles) as well as around the scanning center. The angles are calculated based on the central frequency and diameter of the transducer and the radius of the region-of-interest (ROI). Simulations with point-like absorbers (for point-spread-function evaluation) and a vasculature phantom (for quality assessment), and experiments with ten 0.5 mm-diameter pencil leads and a leaf skeleton phantom are used for evaluation of the proposed approach. The results show that a location-independent tangential resolution is achieved with 150 spatial sampling and central rotations with angles of ±8°/±16°. With further developments, the proposed detection strategy can replace the conventional detection (rotating a transducer around ROI) in PAT.","Artifacts reduction; Finite transducer size; Photoacoustic tomography; Tangential resolution; Virtual source","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:0aa74b23-7fad-41ca-ba40-55666836df52","http://resolver.tudelft.nl/uuid:0aa74b23-7fad-41ca-ba40-55666836df52","Dispersing and Sonoporating Biofilm-Associated Bacteria with Sonobactericide","Lattwein, K.R. (Erasmus MC); Beekers, Inés (Erasmus MC); Kouijzer, Joop J.P. (Erasmus MC); Leon-Grooters, Mariël (Erasmus MC); Langeveld, Simone A.G. (Erasmus MC); van Rooij, Tom (Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); van Wamel, Willem J.B. (Erasmus MC); Kooiman, Klazina (Erasmus MC)","","2022","Bacteria encased in a biofilm poses significant challenges to successful treatment, since both the immune system and antibiotics are ineffective. Sonobactericide, which uses ultrasound and microbubbles, is a potential new strategy for increasing antimicrobial effectiveness or directly killing bacteria. Several studies suggest that sonobactericide can lead to bacterial dispersion or sonoporation (i.e., cell membrane permeabilization); however, real-time observations distinguishing individual bacteria during and directly after insonification are missing. Therefore, in this study, we investigated, in real-time and at high-resolution, the effects of ultrasound-induced microbubble oscillation on Staphylococcus aureus biofilms, without or with an antibiotic (oxacillin, 1 µg/mL). Biofilms were exposed to ultrasound (2 MHz, 100–400 kPa, 100–1000 cycles, every second for 30 s) during time-lapse confocal microscopy recordings of 10 min. Bacterial responses were quantified using post hoc image analysis with particle counting. Bacterial dispersion was observed as the dominant effect over sonoporation, resulting from oscillating microbubbles. Increasing pressure and cycles both led to significantly more dispersion, with the highest pressure leading to the most biofilm removal (up to 83.7%). Antibiotic presence led to more variable treatment responses, yet did not significantly impact the therapeutic efficacy of sonobactericide, suggesting synergism is not an immediate effect. These findings elucidate the direct effects induced by sonobactericide to best utilize its potential as a biofilm treatment strategy.","antibiotic; bacteria; biofilm; dispersion; microbubble; sonobactericide; sonoporation; Staphylococcus aureus; ultrasound","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:ae82ccb1-1a78-47c3-a2d0-2c86a9f15046","http://resolver.tudelft.nl/uuid:ae82ccb1-1a78-47c3-a2d0-2c86a9f15046","Dreaming the wrong dream: An exploratory case study of a policy change toward sustainable urban development in a medium-sized Chinese city","Song, Y. (TU Delft Organisation & Governance; Erasmus Universiteit Rotterdam); de Jong, W.M. (TU Delft Organisation & Governance; Erasmus Universiteit Rotterdam; Fudan University); Stead, D. (TU Delft Spatial Planning and Strategy; Aalto University); Yang, Wei (Northeastern University); Wang, B. (TU Delft Urban Development Management)","","2022","Sustainable urban transformation has become a mantra for Chinese cities. While most studies focus on sustainable urbanization in megacities, the far larger number of medium-sized cities is understudied, although the latter face more severe urban problems. This article develops a framework for examining policy change in sustainable urban development initiated at the central level and reactions, tensions, and implementation issues emerging at the local level. It focuses on an in-depth case study of the challenges in realizing a transition from quantity-oriented pro-growth policies to sustainable quality-oriented ones in a medium-sized Chinese city. We find that there is evidence of changes in long-term values and goals toward sustainability at the levels of both central and local government, but also great inconsistency between goals on paper and policy implementation in practice. Sustainability in urban development is much harder to realize as local officials see urban development as a major means to maintain local economic growth, which can be separated from other issues in ecological preservation. The article concludes with a roadmap for future studies focusing on medium-sized cities, especially indicating how narratives on sustainable urban development hide from view financial and environmental risks generated by the actual implementation of the dominant aggressive urban pro-growth model.","infrastructure development; medium-sized cities; Policy paradigm; sustainable urban transition; urban growth","en","journal article","","","","","","","","","","","Organisation & Governance","","",""
"uuid:8b41e517-3894-408c-863c-ab6e7eeb074f","http://resolver.tudelft.nl/uuid:8b41e517-3894-408c-863c-ab6e7eeb074f","Electrochemical Reduction of CO2to Oxalic Acid: Experiments, Process Modeling, and Economics","Boor, Vera (Student TU Delft); Frijns, Jeannine E.B.M. (Student TU Delft); Laitinen, Antero T. (VTT Technical Research Center of Finland); Goetheer, Earl (TNO); van den Broeke, L.J.P. (TU Delft Engineering Thermodynamics); Kortlever, R. (TU Delft Large Scale Energy Storage); de Jong, W. (TU Delft Large Scale Energy Storage); Moultos, O. (TU Delft Engineering Thermodynamics); Vlugt, T.J.H. (TU Delft Engineering Thermodynamics); Ramdin, M. (TU Delft Engineering Thermodynamics)","","2022","We performed H-cell and flow cell experiments to study the electrochemical reduction of CO2 to oxalic acid (OA) on a lead (Pb) cathode in various nonaqueous solvents. The effects of anolyte, catholyte, supporting electrolyte, temperature, water content, and cathode potential on the Faraday efficiency (FE), current density (CD), and product concentration were investigated. We show that a high FE for OA can be achieved (up to 90%) at a cathode potential of -2.5 V vs Ag/AgCl but at relatively low CDs (10-20 mA/cm2). The FE of OA decreases significantly with increasing water content of the catholyte, which causes byproduct formation (e.g., formate, glycolic acid, and glyoxylic acid). A process design and techno-economic evaluation of the electrochemical conversion of CO2 to OA is presented. The results show that the electrochemical route for OA production can compete with the fossil-fuel based route for the base case scenario (CD of 100 mA/cm2, OA FE of 80%, cell voltage of 4 V, electrolyzer CAPEX of $20000/m2, electricity price of $30/MWh, and OA price of $1000/ton). A sensitivity analysis shows that the market price of OA has a huge influence on the economics. A market price of at least $700/ton is required to have a positive net present value and a payback time of less than 10 years. The performance and economics of the process can be further improved by increasing the CD and FE of OA by using gas diffusion electrodes and eliminating water from the cathode, lowering the cell voltage by increasing the conductivity of the electrolyte solutions, and developing better OA separation methods.","","en","journal article","","","","","","","","","","","Engineering Thermodynamics","","",""
"uuid:bca1d1b8-8e13-4be5-8a90-d66c641dc7c4","http://resolver.tudelft.nl/uuid:bca1d1b8-8e13-4be5-8a90-d66c641dc7c4","Improving Lateral Resolution in 3-D Imaging With Micro-beamforming Through Adaptive Beamforming by Deep Learning","Ossenkoppele, B.W. (TU Delft ImPhys/Imaging Physics; TU Delft ImPhys/Medical Imaging); Luijten, Ben (Eindhoven University of Technology); Bera, Deep (Philips Research); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Verweij, M.A. (TU Delft Technology, Policy and Management; Erasmus MC); van Sloun, Ruud J.G. (Eindhoven University of Technology; Philips Research)","","2023","There is an increased desire for miniature ultrasound probes with small apertures to provide volumetric images at high frame rates for in-body applications. Satisfying these increased requirements makes simultaneous achievement of a good lateral resolution a challenge. As micro-beamforming is often employed to reduce data rate and cable count to acceptable levels, receive processing methods that try to improve spatial resolution will have to compensate the introduced reduction in focusing. Existing beamformers do not realize sufficient improvement and/or have a computational cost that prohibits their use. Here we propose the use of adaptive beamforming by deep learning (ABLE) in combination with training targets generated by a large aperture array, which inherently has better lateral resolution. In addition, we modify ABLE to extend its receptive field across multiple voxels. We illustrate that this method improves lateral resolution both quantitatively and qualitatively, such that image quality is improved compared with that achieved by existing delay-and-sum, coherence factor, filtered-delay-multiplication-and-sum and Eigen-based minimum variance beamformers. We found that only in silica data are required to train the network, making the method easily implementable in practice.","Adaptive beamforming; Deep learning; Matrix transducers; Micro-beamforming; Volumetric imaging","en","journal article","","","","","","","","","Technology, Policy and Management","ImPhys/Imaging Physics","ImPhys/Medical Imaging","","",""
"uuid:27e20e06-0128-4201-aaf6-5f197b33f241","http://resolver.tudelft.nl/uuid:27e20e06-0128-4201-aaf6-5f197b33f241","Coupling Two Ultra-high-Speed Cameras to Elucidate Ultrasound Contrast-Mediated Imaging and Therapy","Li, H. (Erasmus MC); Li, X. (TU Delft ImPhys/Medical Imaging); Collado Lara, G. (Erasmus MC); Lattwein, K.R. (Erasmus MC); Mastik, Frits (Erasmus MC); Beurskens, Robert (Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Verweij, M.A. (TU Delft Technology, Policy and Management; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Kooiman, Klazina (Erasmus MC)","","2023","Ultrasound contrast-mediated medical imaging and therapy both rely on the dynamics of micron- and nanometer-sized ultrasound cavitation nuclei, such as phospholipid-coated microbubbles and phase-change droplets. Ultrasound cavitation nuclei respond non-linearly to ultrasound on a nanosecond time scale that necessitates the use of ultra-high-speed imaging to fully visualize these dynamics in detail. In this study, we developed an ultra-high-speed optical imaging system that can record up to 20 million frames per second (Mfps) by coupling two small-sized, commercially available, 10-Mfps cameras. The timing and reliability of the interleaved cameras needed to achieve 20 Mfps was validated using two synchronized light-emitting diode strobe lights. Once verified, ultrasound-activated microbubble responses were recorded and analyzed. A unique characteristic of this coupled system is its ability to be reconfigured to provide orthogonal observations at 10 Mfps. Acoustic droplet vaporization was imaged from two orthogonal views, by which the 3-D dynamics of the phase transition could be visualized. This optical imaging system provides the temporal resolution and experimental flexibility needed to further elucidate the dynamics of ultrasound cavitation nuclei to potentiate the clinical translation of ultrasound-mediated imaging and therapy developments.","Cavitation; Droplet; Microbubble; Ultra-high-speed imaging; Ultrasound; Ultrasound contrast agents","en","journal article","","","","","","","","","Technology, Policy and Management","","ImPhys/Medical Imaging","","",""
"uuid:94716349-d26d-4df5-8726-4ea7d7929154","http://resolver.tudelft.nl/uuid:94716349-d26d-4df5-8726-4ea7d7929154","Differences in levels of accessibility: The importance of spatial scale when measuring distributions of the accessibility of health and emergency services","van Wee, G.P. (TU Delft Transport and Logistics); de Jong, Tom (Stellenbosch University)","","2023","This paper explores to what extent inequalities in travel times, measured via the Gini index, depend on the spatial scale at which (average) travel times are measured. By using the new concept of Dedicated Accessibility Points, for the Netherlands we calculated average travel times at four spatial levels, ranging from virtually individual addresses to the level of municipalities. Travel times by car and bicycle to three medical points of interest are calculated: pharmacies, family doctors, and hospitals, as well as travel times by car from three other points of interest: ambulance stations, fire stations and police stations. At the level of individual addresses the errors made due to spatial aggregation is absent, but at higher spatial scales it plays a role. The results show that the Gini index is heavily influenced by the spatial scale at which the indices are calculated, with smaller indices at higher spatial scales. We discuss the implications of these differences for research and policy.","Accessibility; Equity; MAUP; Spatial aggregation","en","journal article","","","","","","","","","","","Transport and Logistics","","",""
"uuid:4eb11c44-963c-402e-90fc-ba1a9b3d9c92","http://resolver.tudelft.nl/uuid:4eb11c44-963c-402e-90fc-ba1a9b3d9c92","Mechanical overtone frequency combs","de Jong, M.H.J. (TU Delft QN/Groeblacher Lab; TU Delft Dynamics of Micro and Nano Systems; Kavli institute of nanoscience Delft); Ganesan, Adarsh (National Institute of Standards and Technology; Ahmedabad University); Cupertino, A. (TU Delft Dynamics of Micro and Nano Systems); Groeblacher, S. (TU Delft QN/Groeblacher Lab; Kavli institute of nanoscience Delft); Norte, R.A. (TU Delft QN/Groeblacher Lab; TU Delft Dynamics of Micro and Nano Systems; Kavli institute of nanoscience Delft)","","2023","Mechanical frequency combs are poised to bring the applications and utility of optical frequency combs into the mechanical domain. So far, their main challenge has been strict requirements on drive frequencies and power, which complicate operation. We demonstrate a straightforward mechanism to create a frequency comb consisting of mechanical overtones (integer multiples) of a single eigenfrequency, by monolithically integrating a suspended dielectric membrane with a counter-propagating optical trap. The periodic optical field modulates the dielectrophoretic force on the membrane at the overtones of a membrane’s motion. These overtones share a fixed frequency and phase relation, and constitute a mechanical frequency comb. The periodic optical field also creates an optothermal parametric drive that requires no additional power or external frequency reference. This combination of effects results in an easy-to-use mechanical frequency comb platform that requires no precise alignment, no additional feedback or control electronics, and only uses a single, mW continuous wave laser beam. This highlights the overtone frequency comb as the straightforward future for applications in sensing, metrology and quantum acoustics.","OA-Fund TU Delft","en","journal article","","","","","","","","","","","QN/Groeblacher Lab","","",""
"uuid:4dfe907c-6e7a-481d-9350-97c211ae1286","http://resolver.tudelft.nl/uuid:4dfe907c-6e7a-481d-9350-97c211ae1286","Variable and Orbital-Dependent Spin-Orbit Field Orientations in an InSb Double Quantum Dot Characterized via Dispersive Gate Sensing","Han, L. (TU Delft Qubit Research Division; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Chan, M. (TU Delft QRD/Wimmer Group; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); de Jong, D. (TU Delft BUS/Quantum Delft; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Prosko, C.G. (TU Delft QRD/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Badawy, Ghada (Eindhoven University of Technology); Gazibegovic, Sasa (Eindhoven University of Technology); Bakkers, Erik P.A.M. (Eindhoven University of Technology); Kouwenhoven, Leo P. (TU Delft QN/Kouwenhoven Lab; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Malinowski, F.K. (TU Delft BUS/TNO STAFF; TU Delft QuTech Advanced Research Centre; Kavli institute of nanoscience Delft); Pfaff, Wolfgang (University of Illinois at Urbana-Champaign)","","2023","Utilizing dispersive gate sensing (DGS), we investigate the spin-orbit field (BSO) orientation in a many-electron double quantum dot (DQD) defined in an InSb nanowire. While characterizing the interdot tunnel couplings, we find the measured dispersive signal depends on the electron-charge occupancy, as well as on the amplitude and orientation of the external magnetic field. The dispersive signal is mostly insensitive to the external field orientation when a DQD is occupied by a total odd number of electrons. For a DQD occupied by a total even number of electrons, the dispersive signal is reduced when the finite external magnetic field aligns with the effective BSO orientation. This fact enables the identification of BSO orientations for different DQD electron occupancies. The BSO orientation varies drastically between charge transitions, and is generally neither perpendicular to the nanowire nor in the chip plane. Moreover, BSO is similar for pairs of transitions involving the same valence orbital, and varies between such pairs. Our work demonstrates the practicality of DGS in characterizing spin-orbit interactions in quantum dot systems, without requiring any current flow through the device.","","en","journal article","","","","","","","","","","Qubit Research Division","QRD/Wimmer Group","","",""
"uuid:4c9a795b-efa4-4a91-bbf6-cce0e4032378","http://resolver.tudelft.nl/uuid:4c9a795b-efa4-4a91-bbf6-cce0e4032378","Development of a simulator for training of fetoscopic myelomeningocele surgery","Spoor, Jochem K.H. (Erasmus MC); van Gastel, Lis (Erasmus MC); Tahib, Fatima (Erasmus MC); van Grieken, Amanda (Erasmus MC); van Weteringen, Willem (Erasmus MC); Sterke, F. (TU Delft Medical Instruments & Bio-Inspired Technology; Erasmus MC); Baschat, Ahmet A. (Johns Hopkins University); Miller, Jena L. (Johns Hopkins University); de Jong, Tjeerd H.R. (Erasmus MC); Wijnen, René M.H. (Erasmus MC); Eggink, Alex E. (Erasmus MC); DeKoninck, Philip L.J. (Erasmus MC)","","2023","Objective: To develop a realistic simulation model for laparotomy-assisted fetoscopic spina bifida aperta (SBa) surgery, to be used for training purposes and preoperative planning. Methods: The predefined general requirement was a realistic model of an exteriorized uterus, allowing all neurosurgical steps of the intervention. The uterus was modelled using ultrasound and MRI images of a 25 weeks’ gravid uterus, consisting of flexible polyurethane foam coated with pigmented silicone. The fetal model, contained an opening on the dorsal side for a customizable spinal insert with all the aspects of a SBa, including a cele, placode, and myofascial and skin layer. The model was assessed in a series of validation experiments. Results: Production costs are low, uterus and fetus are reusable. Placental localization and the level and size of the spinal defect are adjustable, enabling case-specific adaptations. All aspects of the simulator were scored close to realistic or higher for both appearance and functional capacities. Conclusions: This innovative model provides an excellent training opportunity for centers that are starting a fetoscopic SBa repair program. It is the first simulation model with adjustable spinal defect and placental localisation. Further objective validation is required, but the potential for using this model in preoperative planning is promising.","","en","journal article","","","","","","","","","","","Medical Instruments & Bio-Inspired Technology","","",""
"uuid:8a4900e5-644d-4f41-9f29-52bf9d8ac57c","http://resolver.tudelft.nl/uuid:8a4900e5-644d-4f41-9f29-52bf9d8ac57c","Intra-renal microcirculatory alterations on non-traumatic hemorrhagic shock induced acute kidney injury in pigs","Ergin, Bülent (Erasmus MC); van Rooij, Tom (Erasmus MC); Lima, Alex (Erasmus MC); Ince, Yasin (Universiteit van Amsterdam); Specht, Patricia Ac (Erasmus MC); Mik, E.G. (Erasmus MC); Aksu, Ugur (Istanbul University); Yavuz-Aksu, Berna (Istanbul Technical University); de Jong, N. (TU Delft ImPhys/De Jong group; Erasmus MC)","","2023","Acute kidney injury (AKI) is frequently seen in patients with hemorrhagic shock due to hypotension, tissue hypoxia, and inflammation despite adequate resuscitation. There is a lack of information concerning the alteration of renal microcirculation and perfusion during shock and resuscitation. The aim of this study was to investigate the possible role of renal microcirculatory alterations on development of renal dysfunction in a pig model of non-traumatic hemorrhagic shock (HS) induced AKI. Fully instrumented female pigs were divided into the two groups as Control (n = 6) and HS (n = 11). HS was achieved by withdrawing blood until mean arterial pressure (MAP) reached around 50 mmHg. After an hour cessation period, fluid resuscitation with balanced crystalloid was started for the duration of 1 h. The systemic and renal hemodynamics, renal microcirculatory perfusion (contrast-enhanced ultrasound (CEUS)) and the sublingual microcirculation were measured. CEUS peak enhancement was significantly increased in HS during shock, early-, and late resuscitation indicating perfusion defects in the renal cortex (p < 0.05 vs. baseline, BL) despite a stable renal blood flow (RBF) and urine output. Following normalization of systemic hemodynamics, we observed persistent hypoxia (high lactate) and high red blood cell (RBC) velocity just after initiation of resuscitation resulting in further endothelial and renal damage as shown by increased plasma sialic acid (p < 0.05 vs. BL) and NGAL levels. We also showed that total vessel density (TVD) and functional capillary density (FCD) were depleted during resuscitation (p < 0.05). In this study, we showed that the correction of systemic hemodynamic variables may not be accompanied with the improvement of renal cortical perfusion, intra-renal blood volume and renal damage following fluid resuscitation. We suggest that the measurement of renal injury biomarkers, systemic and renal microcirculation can be used for guiding to the optimization of fluid therapies.","Damage; Hemorrhagic shock; Renal perfusion; Resuscitation","en","journal article","","","","","","","","","","","ImPhys/De Jong group","","",""
"uuid:03e92f25-9e64-45ea-a096-540fe212834a","http://resolver.tudelft.nl/uuid:03e92f25-9e64-45ea-a096-540fe212834a","MRI-based synthetic CT in the detection of knee osteoarthritis: Comparison with CT","Arbabi, Saeed (University Medical Center Utrecht); Foppen, Wouter (University Medical Center Utrecht); Gielis, Willem Paul (University Medical Center Utrecht); van Stralen, Marijn (MRIguidance B.V); Jansen, Mylène (University Medical Center Utrecht); Arbabi, Vahid (University Medical Center Utrecht; Orthopaedic‐ Biomechanics Research Group); de Jong, Pim A. (University Medical Center Utrecht); Weinans, Harrie (TU Delft Biomaterials & Tissue Biomechanics; University Medical Center Utrecht); Seevinck, Peter (Image Sciences Institute; MRIguidance B.V)","","2023","Magnetic resonance Imaging is the gold standard for assessment of soft tissues; however, X-ray-based techniques are required for evaluating bone-related pathologies. This study evaluated the performance of synthetic computed tomography (sCT), a novel MRI-based bone visualization technique, compared with CT, for the scoring of knee osteoarthritis. sCT images were generated from the 3T T1-weighted gradient-echo MR images using a trained machine learning algorithm. Two readers scored the severity of osteoarthritis in tibiofemoral and patellofemoral joints according to OACT, which enables the evaluation of osteoarthritis, from its characteristics of joint space narrowing, osteophytes, cysts and sclerosis in CT (and sCT) images. Cohen's κ was used to assess the interreader agreement for each modality, and intermodality agreement of CT- and sCT-based scores for each reader. We also compared the confidence level of readers for grading CT and sCT images using confidence scores collected during grading. Inter-reader agreement for tibiofemoral and patellofemoral joints were almost-perfect for both modalities (κ = 0.83–0.88). The intermodality agreement of osteoarthritis scores between CT and sCT was substantial to almost-perfect for tibiofemoral (κ = 0.63 and 0.84 for the two readers) and patellofemoral joints (κ = 0.78 and 0.81 for the two readers). The analysis of diagnosis confidence scores showed comparable visual quality of the two modalities, where both are showing acceptable confidence levels for scoring OA. In conclusion, in this single-center study, sCT and CT were comparable for the scoring of knee OA.","CT; MRI; neural networks; osteoarthritis; synthetic CT","en","journal article","","","","","","","","","","","Biomaterials & Tissue Biomechanics","","",""
"uuid:ba8095da-4952-4b0f-8ab1-448b392b8deb","http://resolver.tudelft.nl/uuid:ba8095da-4952-4b0f-8ab1-448b392b8deb","Unravelling the Effect of Activators used in The Synthesis of Biomass-Derived Carbon Electrocatalysts on the Electrocatalytic Performance for CO2 Reduction","Fu, S. (TU Delft Large Scale Energy Storage); Li, M. (TU Delft ChemE/Product and Process Engineering); Asperti, S. (TU Delft Large Scale Energy Storage); de Jong, W. (TU Delft Large Scale Energy Storage); Kortlever, R. (TU Delft Large Scale Energy Storage)","","2023","N-doped carbon materials can be efficient and cost-effective catalysts for the electrochemical CO2 reduction reaction (CO2RR). Activators are often used in the synthesis process to increase the specific surface area and porosity of these carbon materials. However, owing to the diversity of activators and the differences in physicochemical properties that these activators induce, the influence of activators used for the synthesis of N-doped carbon catalysts on their electrochemical performance is unclear. In this study, a series of bagasse-derived N-doped carbon catalysts is prepared with the assistance of different activators to understand the correlation between activators, physicochemical properties, and electrocatalytic performance for the CO2RR. The properties of N-doped carbon catalysts, such as N-doping content, microstructure, and degree of graphitization, are found to be highly dependent on the type of activator applied in the synthesis procedure. Moreover, the overall CO2RR performance of the synthesized electrocatalysts is not determined only by the N-doping level and the configuration of the N-dopant, but rather by the overall surface chemistry, where the porosity and the degree of graphitization are jointly responsible for significant differences in CO2RR performance.","biomass; carbon activation; CO valorization; doping; electrocatalysis","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:2972e6b3-f8f9-4f4b-9641-d27e2a0cd7fc","http://resolver.tudelft.nl/uuid:2972e6b3-f8f9-4f4b-9641-d27e2a0cd7fc","Introducing a classification framework to urban waste policy: Analysis of sixteen zero-waste cities in China","Ma, Wenting (Harbin Institute of Technology; Erasmus Universiteit Rotterdam); de Jong, W.M. (Erasmus Universiteit Rotterdam; Fudan University); Zisopoulos, Filippos (Erasmus Universiteit Rotterdam); Hoppe, T. (TU Delft Multi Actor Systems)","","2023","Chinese cities are experiencing rapid urban development while facing severe challenges of environmental pollution. China's central government has proposed several policies to reduce urban waste. However, little is known about the adoption of these policies. Here, we raise the question how can circular policies be classified, and how can this classification be applied to cities in China that wish become zero-waste cities? We develop a framework to classify urban waste policies according to: (a) the “5R” principles (“Rethink”, “Reduce”, “Reuse”, “Recycle”, and “Recover”), (b) four types of waste (industrial, agricultural, municipal, and hazardous) and (c) six types of policy instruments (legal, economic, network, communication, innovation and projects). We use this framework to analyze urban waste policies implemented by sixteen zero-waste demonstration projects in China. The present study emphasizes combinations of policy instruments, “R” strategy and waste type in the implementation of zero-waste policies. We find that the “Rethink”, “Reduce”, and “Recycle” principles have been widely implemented by local authorities in contrast to the principles “Reuse” and “Recover”. Local governments address waste management by embracing regulations, innovation instruments, and project arrangements, while network-based, economic, or communicative policy instruments are used less often. Based on the results we suggest that local governments embrace a comprehensive approach to the use of the “5R” principles and deploy a diverse portfolio of policy instruments.","China; Circular economy; Policy instruments; Urban waste policies; Zero-waste cities; “5R” principles","en","journal article","","","","","","","","","","Multi Actor Systems","","","",""
"uuid:2353a578-aa10-4e35-8232-a3722e9afb86","http://resolver.tudelft.nl/uuid:2353a578-aa10-4e35-8232-a3722e9afb86","Regenerative economics at the service of islands: Assessing the socio-economic metabolism of Samothraki in Greece","Zisopoulos, Filippos K. (Erasmus Universiteit Rotterdam; Student TU Delft); Noll, Dominik (BOKU-University of Natural Resources and Life Sciences; University of Évora); Singh, Simron J. (University of Waterloo); Schraven, D.F.J. (TU Delft Integral Design & Management); de Jong, Martin (Erasmus Universiteit Rotterdam; Fudan University); Fath, Brian D. (Towson University; University of Edinburgh; International Institute for Applied Systems Analysis); Goerner, Sally (University of Edinburgh); Webster, Ken (Linköping University); Fiscus, Dan (University of Edinburgh); Ulanowicz, Robert E. (University of Edinburgh; University of Florida)","","2023","For many islands, the answer to the question “why a locally, self-sustaining, and regenerative economy is needed?” is clear. The struggle often lies in the “how”. Here, we argue that tools from regenerative economics, which follow an island economy-as-an-organism analogy, offer valuable and complementary insights to socio-metabolic research. Indicators from flow-based and information-based ecological network analysis can quantify properties of an island's socio-economic metabolism (SEM) which are related to cycling, resilience, and degree of mutualism, among others. To illustrate the applicability of these methods, we select Samothraki in Greece as a case study. Results show that over the years the island became very efficient in streamlining imported resources, experiencing physical growth as indicated by a substantial increase in its total material throughput. This growth was attributed to a high degree of order (i.e., network efficiency) endowed by the constraining (ordered) part of the linear structure of the island's SEM. The disordered part of its SEM which is related to resilience, played a much smaller role which became progressively more important over the years, albeit to a limited degree. While the island exhibits an increasing trend in its robustness, its value over the years studied was well below what is typically observed for healthy natural ecosystems, and its current SEM has a very low ability to generate internal flow activity and cycling of resources per unit input. This limited robustness is due to the island's dependency on imports but also due to its linear SEM which had a very small number of feedback loops in its network. A scenario analysis showed that a reticulated network structure would theoretically endow the island with increased resilience, and hence robustness, by allowing for more internal resource flow activity to be circulated as regenerative re-investment. This article highlights that methods from regenerative economics can be used as diagnostic tools to assess and monitor the impact of strategies related to circular economy interventions on network properties, and to illuminate their effect on the regenerative potential of islands.","Ascendency analysis; Circular economy; Ecological network analysis; Island metabolism; Resilience; Robustness","en","journal article","","","","","","","","","","","Integral Design & Management","","",""
"uuid:cff0a6be-a589-4768-a1ec-cefc864c99c7","http://resolver.tudelft.nl/uuid:cff0a6be-a589-4768-a1ec-cefc864c99c7","Using salt marshes for coastal protection: Effective but hard to get where needed most","Marin-Diaz, Beatriz (NIOZ Royal Netherlands Institute for Sea Research; Rijksuniversiteit Groningen); van der Wal, Daphne (NIOZ Royal Netherlands Institute for Sea Research; University of Twente); Kaptein, Leon (Rijksuniversiteit Groningen); Martinez-Garcia, Pol (The Fieldwork Company); Lashley, Christopher H. (TU Delft Hydraulic Structures and Flood Risk; University of Delaware); de Jong, Kornelis (Regional Water Authority Noorderzijlvest); Nieuwenhuis, Jan Willem (Regional Water Authority Noorderzijlvest); Govers, Laura L. (NIOZ Royal Netherlands Institute for Sea Research; Rijksuniversiteit Groningen); Olff, Han (Rijksuniversiteit Groningen); Bouma, Tjeerd J. (NIOZ Royal Netherlands Institute for Sea Research; Universiteit Utrecht; Rijksuniversiteit Groningen)","","2023","Salt marshes fronting coastal structures, such as seawalls and dikes, may offer important ecosystem-based coastal defence by reducing the wave loading and run-up levels during storms. We question (i) how the long-term salt marsh development in the Dutch Wadden Sea relates to the tidal-flat foreshore bathymetry and (ii) how the wave run-up onto dikes, which enhances the risk of dike failure, depends on foreshore bathymetry, the presence/absence of marshes, marsh vegetation properties, tidal range and wind exposure. We analysed 15 years of vegetation and bathymetry maps along the entire Dutch Wadden Sea coast, in combination with detailed process-based measurements at five locations during 3 years, to understand where salt marshes naturally form and what features determine their contribution to coastal protection. The horizontal extent of marshes along the dikes remained relatively stable over the past decade. The presence of marshes was associated with higher elevations of adjacent tidal flats (above ~0.5 m NAP), while landward-directed marsh retreat was associated with surface erosion of the fronting tidal flats. Wave run-up during storms was lower at sites with wider marshes and higher foreshore elevations. This was attributed to the marsh attenuation effect, which led to a reduction in wave heights at the dike toe. As the tidal range varies across the Dutch Wadden Sea, areas to the East with generally higher water levels experienced higher wave run-up. Synthesis and applications. We found that (i) marshes, where present, effectively protected the dikes from wave loading and (ii) the sites where marshes typically do not develop spontaneously were the most vulnerable to high wave run-up. This catch-22 problem implies that increasing reliance on nature-based coastal defences along soft-bottom coasts may require human interventions to stimulate marsh formation at the locations where it is most needed. Alternatively, ‘hard engineering’ solutions may remain necessary where implementing nature-based solutions are either too costly, unachievable, or at the expense of other ecological values, such as causing the loss of mudflats that are important for migratory birds.","beach wrack; flotsam; grazing; nature-based coastal protection; overtopping; sediment dynamics; wave attenuation; wind exposure","en","journal article","","","","","","","","","","","Hydraulic Structures and Flood Risk","","",""
"uuid:7b861972-65fc-4c3e-b8be-9f116dcaf29d","http://resolver.tudelft.nl/uuid:7b861972-65fc-4c3e-b8be-9f116dcaf29d","Hybrid sol-gel coatings for reducing wettability and storage degradation of biomass pellets","Cutz, L. (TU Delft Large Scale Energy Storage); Tiringer, U. (TU Delft Team Peyman Taheri); de Jong, W. (TU Delft Large Scale Energy Storage); Mol, J.M.C. (TU Delft Team Arjan Mol)","","2023","Long transport distances and extended storage of biomass pellets especially in humid environments provide a suitable setting for enhanced degradation in the form of moisture sorption, cracking and attrition. We developed an optically transparent, low-cost and environmentally friendly coating to reduce moisture sorption and storage degradation of pellets. The developed coating is a hybrid sol–gel, based on tetraethoxysilane (TEOS) and 3-glycidoxypropyl-trimethoxysilane (GPTMS) precursors. We coated two types of untreated and one type of torrefied wood pellets and stored them in a climate chamber during 1 month simulating a ship's hold, at a constant condition of 40 °C and 85% relative humidity. After 1 month of storage, the mean water contact angle increased by a factor of two compared to the uncoated ones. The lower wettability of the sol-gel coated untreated pellets compared to the non-coated torrefied pellets might provide an alternative to torrefaction.","Biomass pellets; Biomass treatment; Durability; Hydrophobic coating; Storage","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:a36964ff-6a22-4d1f-aa5a-d902bcb040f4","http://resolver.tudelft.nl/uuid:a36964ff-6a22-4d1f-aa5a-d902bcb040f4","Unlocking system transitions for municipal solid waste infrastructure: A model for mapping interdependencies in a local context","Liu, Z. (TU Delft Integral Design & Management); Schraven, D.F.J. (TU Delft Real Estate Management); de Jong, Martin (Erasmus Universiteit Rotterdam; Fudan University); Hertogh, M.J.C.M. (TU Delft Integral Design & Management; Erasmus Universiteit Rotterdam)","","2023","Rapid global urbanization, urban renewal and changes in people's lifestyles have led to both an increase in waste generation and more complex waste types. In response to these changes, many local governments have invested in municipal solid waste infrastructure (MSWI) to implement circular strategies. However, matching and bridging the costly and logistically complex MSWI with the dynamic social context is a central challenge. In this paper we aim to explore the interdependencies between MSWI and the local social system, and then conceptualize and empirically validate the systemic nature of MSWI. We first review the current MSW treatment methods, corresponding infrastructure, and the challenges facing them. Then, we interrogate system-oriented concepts and use two key insights to set up a conceptual model for mapping the interdependencies in a MSWI system (MSWIS). Finally, a case study of the Dutch city of Almere is used to empirically validate the MSWIS model and identify the social systems that contribute to the development of the MSWIS. The analysis reveals that the development of MSWIS is beyond the municipality's control: efficient resource recovery facilities established by businesses under market rules and waste reuse facilities constructed by social organizations/individuals based on their own needs are key pieces of the puzzle to complete the MSWIS. This highlights the ability of the framework to capture interdependencies that go further than just the formal municipal sphere of influence.","Circular economy; Socio-technical systems; System of systems; Waste infrastructure; Waste management","en","journal article","","","","","","","","","","","Integral Design & Management","","",""
"uuid:1b1bf8a1-766e-459c-be76-3bfa78e916bb","http://resolver.tudelft.nl/uuid:1b1bf8a1-766e-459c-be76-3bfa78e916bb","Membrane proteome of the thermoalkaliphile Caldalkalibacillus thermarum TA2.A1","de Jong, S.I. (TU Delft BT/Environmental Biotechnology); Sorokin, Dimitry Y. (TU Delft BT/Environmental Biotechnology; Russian Academy of Sciences); van Loosdrecht, Mark C.M. (TU Delft BT/Environmental Biotechnology); Pabst, Martin (TU Delft BT/Environmental Biotechnology); McMillan, D.G.G. (TU Delft BT/Biocatalysis)","","2023","Proteomics has greatly advanced the understanding of the cellular biochemistry of microorganisms. The thermoalkaliphile Caldalkalibacillus thermarum TA2.A1 is an organism of interest for studies into how alkaliphiles adapt to their extreme lifestyles, as it can grow from pH 7.5 to pH 11. Within most classes of microbes, the membrane-bound electron transport chain (ETC) enables a great degree of adaptability and is a key part of metabolic adaptation. Knowing what membrane proteins are generally expressed is crucial as a benchmark for further studies. Unfortunately, membrane proteins are the category of proteins hardest to detect using conventional cellular proteomics protocols. In part, this is due to the hydrophobicity of membrane proteins as well as their general lower absolute abundance, which hinders detection. Here, we performed a combination of whole cell lysate proteomics and proteomics of membrane extracts solubilised with either SDS or FOS-choline-12 at various temperatures. The combined methods led to the detection of 158 membrane proteins containing at least a single transmembrane helix (TMH). Within this data set we revealed a full oxidative phosphorylation pathway as well as an alternative NADH dehydrogenase type II (Ndh-2) and a microaerophilic cytochrome oxidase ba3. We also observed C. thermarum TA2.A1 expressing transporters for ectoine and glycine betaine, compounds that are known osmolytes that may assist in maintaining a near neutral internal pH when the external pH is highly alkaline.","(Poly-) extremophile; alkaliphile; mass spectrometry; membrane; proteomics; solubilisation; thermophile","en","journal article","","","","","","","","","","","BT/Environmental Biotechnology","","",""
"uuid:1d2549a3-b50e-41a7-a14e-115b7662668c","http://resolver.tudelft.nl/uuid:1d2549a3-b50e-41a7-a14e-115b7662668c","Tuning the Properties of N-Doped Biochar for Selective CO2 Electroreduction to CO","Fu, S. (TU Delft Large Scale Energy Storage); Li, M. (TU Delft Interactive Intelligence); de Jong, W. (TU Delft Large Scale Energy Storage); Kortlever, R. (TU Delft Large Scale Energy Storage)","","2023","Nitrogen-doped (N-doped) carbon catalysts have been widely studied for electrochemical CO2 reduction to CO. However, the correlation between the physicochemical properties of N-doped carbon catalysts and their electrocatalytic performance for the CO2RR is still unclear. Herein, a series of N-doped biochar catalysts with different physicochemical properties were synthesized by tuning the carbonization temperature and N-doping level and used for the CO2RR to analyze the structure-performance relationship. The prepared catalysts exhibited massive differences in maximum faradaic efficiency to CO from 26.8 to 94.9% at around −0.8 to −0.9 V vs RHE. In addition, we find that simply increasing the specific surface area and N-doping level of the catalysts does not effectively improve the catalytic performance for the CO2RR. A multivariate correlation analysis reveals a negative correlation between the N-doping content and the electrochemical performance. The porous structural properties exhibit a positive correlation to the FECO but almost no correlation to jCO. Interestingly, improving the degree of graphitization, surface hydrophobicity, the abundance of defects, and optimizing the porosity of the N-doped biochar catalyst can efficiently enhance the catalytic performance for the CO2RR. We conclude that comprehensively analyzing the synergistic effect of various properties of N-doped biochar is critical to reveal structure-activity relationships.","carbon-based electrocatalysts; CO electrochemical reduction; electrocatalysis; N-doped carbon; structure−performance correlation","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:2691bfd9-0c5f-4f34-b6fd-b5ed2ab3121a","http://resolver.tudelft.nl/uuid:2691bfd9-0c5f-4f34-b6fd-b5ed2ab3121a","High-Frame-Rate Volumetric Porcine Renal Vasculature Imaging","Wei, Luxi (Erasmus MC); Wahyulaksana, G. (Erasmus MC); Boni, Enrico (University of Florence); Noothout, E.C. (TU Delft ImPhys/Verweij group); Duncker, Dirk J.; Tortoli, Piero (University of Florence); van der Steen, A.F.W. (TU Delft ImPhys/Medical Imaging; TU Delft ImPhys/Verweij group; Erasmus MC); de Jong, N. (TU Delft ImPhys/De Jong group; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; TU Delft ImPhys/Verweij group; Erasmus MC); Vos, H.J. (TU Delft ImPhys/Verweij group; Erasmus MC)","","2023","Objective: The aim of this study was to assess the feasibility and imaging options of contrast-enhanced volumetric ultrasound kidney vasculature imaging in a porcine model using a prototype sparse spiral array. Methods: Transcutaneous freehand in vivo imaging of two healthy porcine kidneys was performed according to three protocols with different microbubble concentrations and transmission sequences. Combining high-frame-rate transmission sequences with our previously described spatial coherence beamformer, we determined the ability to produce detailed volumetric images of the vasculature. We also determined power, color and spectral Doppler, as well as super-resolved microvasculature in a volume. The results were compared against a clinical 2-D ultrasound machine. Results: Three-dimensional visualization of the kidney vasculature structure and blood flow was possible with our method. Good structural agreement was found between the visualized vasculature structure and the 2-D reference. Microvasculature patterns in the kidney cortex were visible with super-resolution processing. Blood flow velocity estimations were within a physiological range and pattern, also in agreement with the 2-D reference results. Conclusion: Volumetric imaging of the kidney vasculature was possible using a prototype sparse spiral array. Reliable structural and temporal information could be extracted from these imaging results.","3-D ultrasound; Contrast-enhanced; High frame rate; In vivo; Kidney; Vasculature; Volumetric","en","journal article","","","","","","","","","","","ImPhys/Verweij group","","",""
"uuid:4e5b2a7b-7067-4ae6-add4-f73ca1ab4ab3","http://resolver.tudelft.nl/uuid:4e5b2a7b-7067-4ae6-add4-f73ca1ab4ab3","Developing Xiong’an New Area: A new regime for space production in China’s national technopole?","Song, Yun (Guangdong University of Technology); de Jong, Martin (Erasmus Universiteit Rotterdam; Fudan University); Stead, D. (TU Delft Spatial Planning and Strategy; Aalto University); Liu, Z. (TU Delft Integral Design & Management)","","2023","Xiong’an New Area is not only a newly emerging and nationally endorsed technopole, it is also regarded as a test-bed for novel forms of governance and financial management in China. Although it is currently only in its starting phase, Xiong’an demonstrates that various institutional features are very different from those found in traditional technopoles, such as National High-tech Industrial Development Zones (NHTIDZs). How such institutional innovation affects feasibility and viability of the construction and maintenance of new high-tech metropolises is under-studied. This article develops a conceptual framework based on the theory of space production and identifies two types of space production, global industrialization and local urbanization, which are then applied to the NHTIDZs. Analysis of the situation in Xiong’an leads to the conclusion that Xiong’an represents a mode of strong state-led space production within China’s governance modernization. This not only opens the door to a reconsideration of current land finance and social management systems but it also implies that the transferability of its institutional innovations is limited to other cities where imposing greater social control through technologies is possible.","China; Governance modernization; Land finance; Technopole; Xiong’an","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2024-05-13","","","Spatial Planning and Strategy","","",""
"uuid:70b87cf2-919d-4f28-a4e0-b31b368d399a","http://resolver.tudelft.nl/uuid:70b87cf2-919d-4f28-a4e0-b31b368d399a","4D Flow Patterns and Relative Pressure Distribution in a Left Ventricle Model by Shake-the-Box and Proper Orthogonal Decomposition Analysis","Wu, X. (TU Delft ChemE/Transport Phenomena; J.M. Burgers Centre for Fluid Mechanics); Saaid, Hicham (Universiteit Gent); Voorneveld, J.D. (Erasmus MC); Claessens, Tom (Universiteit Gent); Westenberg, Jos J.M. (Leiden University Medical Center); de Jong, N. (Erasmus MC); Bosch, Johan G. (Erasmus MC); Kenjeres, S. (TU Delft ChemE/Transport Phenomena; J.M. Burgers Centre for Fluid Mechanics)","","2023","Purpose: Intraventricular blood flow dynamics are associated with cardiac function. Accurate, noninvasive, and easy assessments of hemodynamic quantities (such as velocity, vortex, and pressure) could be an important addition to the clinical diagnosis and treatment of heart diseases. However, the complex time-varying flow brings many challenges to the existing noninvasive image-based hemodynamic assessments. The development of reliable techniques and analysis tools is essential for the application of hemodynamic biomarkers in clinical practice. Methods: In this study, a time-resolved particle tracking method, Shake-the-Box, was applied to reconstruct the flow in a realistic left ventricle (LV) silicone model with biological valves. Based on the obtained velocity, 4D pressure field was calculated using a Poisson equation-based pressure solver. Furthermore, flow analysis by proper orthogonal decomposition (POD) of the 4D velocity field has been performed. Results: As a result of the Shake-the-Box algorithm, we have extracted: (i) particle positions, (ii) particle tracks, and finally, (iii) 4D velocity fields. From the latter, the temporal evolution of the 3D pressure field during the full cardiac cycle was obtained. The obtained maximal pressure difference extracted along the base-to-apex was about 2.7 mmHg, which is in good agreement with those reported in vivo. The POD analysis results showed a clear picture of different scale of vortices in the pulsatile LV flow, together with their time-varying information and corresponding kinetic energy content. To reconstruct 95% of the kinetic energy of the LV flow, only the first six POD modes would be required, leading to significant data reduction. Conclusions: This work demonstrated Shake-the-Box is a promising technique to accurately reconstruct the left ventricle flow field in vitro. The good spatial and temporal resolutions of the velocity measurements enabled a 4D reconstruction of the pressure field in the left ventricle. The application of POD analysis showed its potential in reducing the complexity of the high-resolution left ventricle flow measurements. For future work, image analysis, multi-modality flow assessments, and the development of new flow-derived biomarkers can benefit from fast and data-reducing POD analysis.","Hemodynamics; Left ventricle; Particle tracking; Pressure; Proper orthogonal decomposition; Shake-the-Box","en","journal article","","","","","","","","","","","ChemE/Transport Phenomena","","",""
"uuid:d1c6502f-2240-4d91-be93-0c761eee67ee","http://resolver.tudelft.nl/uuid:d1c6502f-2240-4d91-be93-0c761eee67ee","Shape-locking in architected materials through 3D printed magnetically activated joints","de Jong, P.H. (TU Delft Support Biomechanical Engineering; TU Delft Biomaterials & Tissue Biomechanics); Salvatori, Y.S. (University of Genova); Libonati, F. (University of Genova); Mirzaali, Mohammad J. (TU Delft Biomaterials & Tissue Biomechanics); Zadpoor, A.A. (TU Delft Biomaterials & Tissue Biomechanics)","","2023","Shape morphing is the ability of objects to adapt to different shapes and reduce stress concentrations through increased contact area. This is a common trait of natural and engineered objects and has several applications in, among others, soft robotics and orthopedic implants. Shape morphing is achieved through flexible materials or rigid components with either kinematic or compliant joints. An additional step, namely shape locking, is needed for sustained load support. Activation of a locking mechanism can be done with any energy, among which magnetism is one. Here, we present the implementation of a magnetic locking mechanism for kinematically deformable metamaterial structures that maintain shape and support loads upon locking. The structure consists of 3D printed rigid magnetic and non-magnetic components connected by hinges. We created several prototypes of the proposed designs using two additive manufacturing methods (i.e., material extrusion and multi-material jetting) and demonstrated its application in a closed-loop grid for arbitrary shapes. Moreover, we characterized the performance of the prototypes using mechanical tests and multibody kinematic system simulations. This work highlights the viability of the locking concept and provides design considerations for future applications. Further improvement and optimizations are needed for increased efficiency and effectiveness.","3D printing; Kinematic fixation; Locking mechanism; Magnetism; Shape morphing","en","journal article","","","","","","","","","","","Support Biomechanical Engineering","","",""
"uuid:24038b9a-be2d-4c3c-a471-27ec9fa0aadc","http://resolver.tudelft.nl/uuid:24038b9a-be2d-4c3c-a471-27ec9fa0aadc","A multibody kinematic system approach for the design of shape-morphing mechanism-based metamaterials","de Jong, P.H. (TU Delft Support Biomechanical Engineering); Schwab, A.L. (TU Delft Biomechatronics & Human-Machine Control); Mirzaali, Mohammad J. (TU Delft Biomaterials & Tissue Biomechanics); Zadpoor, A.A. (TU Delft Biomaterials & Tissue Biomechanics)","","2023","Shape-morphing structures have the ability to adapt to various target shapes, offering significant advantages for many applications. However, predicting their behavior presents challenges. Here, we present a method to assess the shape-matching behavior of shape-morphing structures using a multibody systems approach wherein the structure is represented by a collection of nodes and their associated constraints. This representation preserves the kinematic properties of the original structure while allowing for a rigorous treatment of the shape-morphing behavior of the underlying metamaterial. We assessed the utility of the proposed method by applying it to a wide range of 2D/3D sample shape-morphing structures. A modular system of joints and links was also 3D printed for the experimental realization of the systems under study. Both our simulations and the experiments confirmed the ability of the presented technique to capture the true shape-morphing behavior of complex shape-morphing metamaterials.","OA-Fund TU Delft","en","journal article","","","","","","","","","","","Support Biomechanical Engineering","","",""
"uuid:0513246c-1e74-4f83-bb75-50b9ab95855e","http://resolver.tudelft.nl/uuid:0513246c-1e74-4f83-bb75-50b9ab95855e","Hydrothermal liquefaction of Elaeis guineensis trunks: Lessons learned from a case study in Guatemala","Cutz, L. (TU Delft Large Scale Energy Storage); Maldonado de León, H.A. (TU Delft BT/Bioprocess Engineering); Zambrano, Gamaliel (Universidad del Valle de Guatemala); Al-Naji, Majd (Technical University of Berlin); de Jong, W. (TU Delft Large Scale Energy Storage)","","2023","The oil palm industry has been under public scrutiny during the last decades due to environmental and social issues related to its practices. Oil palm (Elaeis guineensis Jacq.) trunks (OPTs) are of special interest as they are left idle in the field after the replanting process which is performed every 25 years. This common practice results in harvesting challenges, phytosanitary risks, and a loss of bioenergy potential. Due to their high moisture content and fibrous nature, OPTs present a problem for traditional conversion processes that require a dry and homogeneous material. This study evaluates the feasibility of converting OPTs into a bio-crude oil and biochar to increase the sustainability of the oil palm sector. To date, research efforts have primarily focused on hydrothermal liquefaction (HTL) of OPT without catalysts, resulting in a limited understanding of the potential of OPTs. Thus, the main novelty of this work is the evaluation of the effects of catalyst dosage (0–5 wt%) on the bio-oil yield, reaction temperature (260–300∘C), and residence time (15–60 min) using a half-fraction experimental design methodology. For this, OPTs extracted from two plantations in Guatemala were used. The maximum bio-oil yield (26.77 ± 3.60 wt%) was found at 260∘C for 15 min and 5 wt% catalyst with a high heating value (HHV) of 19.29 ± 1.33 MJ kg−1. Nonetheless, the bio-oils produced without a catalyst at 300∘C and 15 min have higher HHV (27.63 ± 1.35 MJ kg−1) and are similar to Diesel fuel based on their H/C and O/C ratio. These results indicate that there is a potential trade-off between the bio-crude oil mass yield and HHV when using the catalyst.","Bio-oil; Biomass; Hydrothermal liquefaction; Oil palm residues","en","journal article","","","","","","","","","","","Large Scale Energy Storage","","",""
"uuid:0030ce9f-925e-4792-a2d6-345e52957474","http://resolver.tudelft.nl/uuid:0030ce9f-925e-4792-a2d6-345e52957474","Continuous shear wave measurements for dynamic cardiac stiffness evaluation in pigs","Caenen, Annette (Erasmus MC; Katholieke Universiteit Leuven; Universiteit Gent); Keijzer, Lana (Erasmus MC); Bézy, Stéphanie (Katholieke Universiteit Leuven); Duchenne, Jürgen; Orlowska, Marta (Katholieke Universiteit Leuven); van der Steen, A.F.W. (Erasmus MC); de Jong, N. (TU Delft ImPhys/De Jong group; Erasmus MC); Bosch, Johan G. (Erasmus MC); Voigt, Jens Uwe (Katholieke Universiteit Leuven); D’hooge, Jan; Vos, H.J. (TU Delft ImPhys/Verweij group; Erasmus MC)","","2023","Ultrasound-based shear wave elastography is a promising technique to non-invasively assess the dynamic stiffness variations of the heart. The technique is based on tracking the propagation of acoustically induced shear waves in the myocardium of which the propagation speed is linked to tissue stiffness. This measurement is repeated multiple times across the cardiac cycle to assess the natural variations in wave propagation speed. The interpretation of these measurements remains however complex, as factors such as loading and contractility affect wave propagation. We therefore applied transthoracic shear wave elastography in 13 pigs to investigate the dependencies of wave speed on pressure–volume derived indices of loading, myocardial stiffness, and contractility, while altering loading and inducing myocardial ischemia/reperfusion injury. Our results show that diastolic wave speed correlates to a pressure–volume derived index of operational myocardial stiffness (R = 0.75, p < 0.001), suggesting that both loading and intrinsic properties can affect diastolic wave speed. Additionally, the wave speed ratio, i.e. the ratio of systolic and diastolic speed, correlates to a pressure–volume derived index of contractility, i.e. preload-recruitable stroke work (R = 0.67, p < 0.001). Measuring wave speed ratio might thus provide a non-invasive index of contractility during ischemia/reperfusion injury.","","en","journal article","","","","","","","","","","","ImPhys/De Jong group","","",""
"uuid:20c15493-c789-476a-ae45-3080157c6eeb","http://resolver.tudelft.nl/uuid:20c15493-c789-476a-ae45-3080157c6eeb","A Pitch-Matched Transceiver ASIC With Shared Hybrid Beamforming ADC for High-Frame-Rate 3-D Intracardiac Echocardiography","Hopf, Y.M. (TU Delft Electronic Instrumentation); Ossenkoppele, Boudewine W. (Thoraxcenter); Soozande, Mehdi (Thoraxcenter); Noothout, E.C. (TU Delft ImPhys/Medical Imaging); Chang, Z.Y. (TU Delft Electronic Instrumentation); Chen, Chao (Thoraxcenter); Vos, H.J. (TU Delft ImPhys/Medical Imaging); Bosch, Johan G. (Thoraxcenter); Verweij, M.D. (TU Delft ImPhys/Medical Imaging); de Jong, N. (TU Delft ImPhys/Medical Imaging); Pertijs, M.A.P. (TU Delft Electronic Instrumentation)","","2022","In this article, an application-specific integrated circuit (ASIC) for 3-D, high-frame-rate ultrasound imaging probes is presented. The design is the first to combine element-level, high-voltage (HV) transmitters and analog front-ends, subarray beamforming, and in-probe digitization in a scalable fashion for catheter-based probes. The integration challenge is met by a hybrid analog-to-digital converter (ADC), combining an efficient charge-sharing successive approximation register (SAR) first stage and a compact single-slope (SS) second stage. Application in large ultrasound imaging arrays is facilitated by directly interfacing the ADC with a charge-domain subarray beamformer, locally calibrating interstage gain errors and generating the SAR reference using a power-efficient local reference generator. Additional hardware-sharing between neighboring channels ultimately leads to the lowest reported area and power consumption across miniature ultrasound probe ADCs. A pitch-matched design is further enabled by an efficient split between the core circuitry and a periphery block, the latter including a datalink performing clock data recovery (CDR) and time-division multiplexing (TDM), which leads to a 12-fold total channel count reduction. A prototype of $8{\times }9$ elements was fabricated in a TSMC 0.18- $\mu \text{m}$ HV BCD technology and a 2-D PZT transducer matrix with a pitch of $160 \mu \text{m}$ , and a center frequency of 6 MHz was manufactured on the chip. The imaging device operates at up to 1000 volumes/s, generates 65-V transmit pulses, and has a receive power consumption of only 1.23 mW/element. The functionality has been demonstrated electrically as well as in acoustic and imaging experiments.","3-D ultrasound; Array signal processing; Catheters; high-frame-rate; high-voltage (HV) transmitter; hybrid analog-to-digital converter (ADC); Imaging; intracardiac echocardiography (ICE); Probes; subarray beamforming; successive approximation register (SAR)/single-slope (SS) ADC; Transducers; Transmitters; Ultrasonic imaging; ultrasound application-specific integrated circuit (ASIC)","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2023-07-01","","","Electronic Instrumentation","","",""
"uuid:cd5ed501-6ff9-4bef-a7ae-ddc768643f72","http://resolver.tudelft.nl/uuid:cd5ed501-6ff9-4bef-a7ae-ddc768643f72","A Front-End ASIC With High-Voltage Transmit Switching and Receive Digitization for 3-D Forward-Looking Intravascular Ultrasound Imaging","Tan, M. (TU Delft Electronic Instrumentation); Chen, C. (TU Delft Electronic Instrumentation); Chen, Z. (TU Delft Electronic Instrumentation); Janjic, Jovana (Erasmus MC); Daeichin, V. (TU Delft ImPhys/Acoustical Wavefield Imaging); Chang, Z.Y. (TU Delft Electronic Instrumentation); Noothout, E.C. (TU Delft ImPhys/Acoustical Wavefield Imaging); van Soest, G. (Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation)","","2018","This paper presents an area- and power-efficient application-specified integrated circuit (ASIC) for 3-D forward-looking intravascular ultrasound imaging. The ASIC is intended to be mounted at the tip of a catheter, and has a circular active area with a diameter of 1.5 mm on the top of which a 2-D array of piezoelectric transducer elements is integrated. It requires only four micro-coaxial cables to interface 64 receive (RX) elements and 16 transmit (TX) elements with an imaging system. To do so, it routes high-voltage (HV) pulses generated by the system to selected TX elements using compact HV switch circuits, digitizes the resulting echo signal received by a selected RX element locally, and employs an energy-efficient load-modulation datalink to return the digitized echo signal to the system in a robust manner. A multi-functional command line provides the required sampling clock, configuration data, and supply voltage for the HV switches. The ASIC has been realized in a 0.18-μm HV CMOS technology and consumes only 9.1 mW. Electrical measurements show 28-V HV switching and RX digitization with a 16-MHz bandwidth and 53-dB dynamic range. Acoustical measurements demonstrate successful pulse transmission and reception. Finally, a 3-D ultrasound image of a three-needle phantom is generated to demonstrate the imaging capability.","Cable-count reduction; Catheters; high-voltage (HV) switching; Imaging; Impedance; intravascular ultrasound (IVUS) imaging; piezoelectrical transducer; receive digitization; Switches; Transducers; Ultrasonic imaging; Wires","en","journal article","","","","","","Accepted author manuscript","","","","","Electronic Instrumentation","","",""
"uuid:b6470807-609a-4c16-9ba9-2c05f80fd29d","http://resolver.tudelft.nl/uuid:b6470807-609a-4c16-9ba9-2c05f80fd29d","A Front-End ASIC with Receive Sub-array Beamforming Integrated with a 32 × 32 PZT Matrix Transducer for 3-D Transesophageal Echocardiography","Chen, C. (TU Delft Electronic Instrumentation); Chen, Z. (TU Delft Electronic Instrumentation); Bera, Deep (Erasmus MC); Raghunathan, S.B. (TU Delft ImPhys/Acoustical Wavefield Imaging); Shabanimotlagh, M. (TU Delft ImPhys/Acoustical Wavefield Imaging); Noothout, E.C. (TU Delft ImPhys/Acoustical Wavefield Imaging); Chang, Z.Y. (TU Delft Electronic Instrumentation); Ponte, Jacco (Oldelft Ultrasound); Prins, Christian (Oldelft Ultrasound); Vos, H.J. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Bosch, J.G. (Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation)","","2017","This paper presents a power-and area-efficient front-end application-specific integrated circuit (ASIC) that is directly integrated with an array of 32 × 32 piezoelectric transducer elements to enable next-generation miniature ultrasound probes for real-time 3-D transesophageal echocardiography. The 6.1 × 6.1 mm2 ASIC, implemented in a low-voltage 0.18-μm CMOS process, effectively reduces the number of receive (RX) cables required in the probe's narrow shaft by ninefold with the aid of 96 delay-and-sum beamformers, each of which locally combines the signals received by a sub-array of 3 × 3 elements. These beamformers are based on pipeline-operated analog sample-and-hold stages and employ a mismatch-scrambling technique to prevent the ripple signal associated with the mismatch between these stages from limiting the dynamic range. In addition, an ultralow-power low-noise amplifier architecture is proposed to increase the power efficiency of the RX circuitry. The ASIC has a compact element matched layout and consumes only 0.27 mW/channel while receiving, which is lower than the state-of-the-art circuit. Its functionality has been successfully demonstrated in 3-D imaging experiments.","3-D ultrasound imaging; matrix transducer arrays; sub-array beamforming; transesophageal echocardiography (TEE); ultrasound application-specific integrated circuit (ASIC)","en","journal article","","","","","","","","","","","Electronic Instrumentation","","",""
"uuid:bbbe1759-c11a-45a9-bbee-bf5c358ea278","http://resolver.tudelft.nl/uuid:bbbe1759-c11a-45a9-bbee-bf5c358ea278","A Pitch-Matched Front-End ASIC With Integrated Subarray Beamforming ADC for Miniature 3-D Ultrasound Probes","Chen, C. (TU Delft Electronic Instrumentation; Butterfly Network Inc.); Chen, Z. (TU Delft Electronic Instrumentation); Bera, Deep (Erasmus MC; Philips India Limited); Noothout, E.C. (TU Delft ImPhys/Acoustical Wavefield Imaging); Chang, Z.Y. (TU Delft Electronic Instrumentation); Tan, M. (TU Delft Electronic Instrumentation); Vos, H.J. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Bosch, Johan G. (Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation)","","2018","This paper presents a front-end application-specified integrated circuit (ASIC) integrated with a 2-D PZT matrix transducer that enables in-probe digitization with acceptable power dissipation for the next-generation endoscopic and catheter-based 3-D ultrasound imaging systems. To achieve power-efficient massively parallel analog-to-digital conversion (ADC) in a 2-D array, a 10-bit 30 MS/s beamforming ADC that merges the subarray beamforming and digitization functions in the charge domain is proposed. It eliminates the need for costly intermediate buffers, thus significantly reducing both power consumption and silicon area. Self-calibrated charge references are implemented in each subarray to further optimize the system-level power efficiency. High-speed datalinks are employed in combination with the subarray beamforming scheme to realize a 36-fold channel-count reduction and an aggregate output data rate of 6 Gb/s for a prototype receive array of 24 x 6 elements. The ASIC achieves a record power efficiency of 0.91 mW/element during receive. Its functionality has been demonstrated in both electrical and acoustic imaging experiments.","3-D ultrasound imaging; charge-sharing successive approximation register (SAR) analog-to-digital conversion (ADC); in-probe digitization; miniature probes; subarray beamforming; ultrasound front-end application-specified integrated circuit (ASIC).","en","journal article","","","","","","Accepted Author Manuscript","","","","","Electronic Instrumentation","","",""
"uuid:c41e0155-fe64-475e-9d3c-d6cd9fc56fe9","http://resolver.tudelft.nl/uuid:c41e0155-fe64-475e-9d3c-d6cd9fc56fe9","An Algorithm to Minimize the Zero-Flow Error in Transit-Time Ultrasonic Flow Meters","van Willigen, D.M. (TU Delft Electronic Instrumentation); Neer, Paul L.M.J. van (TNO); Massaad Mouawad, J.M. (TU Delft ImPhys/Medical Imaging); de Jong, N. (TU Delft ImPhys/Medical Imaging); Verweij, M.D. (TU Delft ImPhys/Medical Imaging); Pertijs, M.A.P. (TU Delft Electronic Instrumentation)","","2020","Transit-time ultrasonic flow meters are widely used in industry to measure fluid flow. In practice ultrasonic flow meters either show a zero-flow error or suffer from a significant random error due to a limited signal-to-noise ratio, requiring a significant amount of averaging to achieve good precision. This work presents a method that minimizes the zero-flow error whilst keeping the random error low, independent of the hardware used. The proposed algorithm can adjust to changing zero-flow errors while a flow is present. The technique combines the benefits of two common methods of determining the transit-time difference between the upstream and downstream ultrasonic waves: cross-correlation and zero-crossing detection. The algorithm is verified experimentally using a flow-loop. It is shown that the zero-flow error can be greatly reduced without compromising the random error or increasing circuit complexity.","Cross correlation; flow measurement; reciprocity; transit time; ultrasonic flowmeter; zero crossings; zero-flow error","en","journal article","","","","","","","","","","","Electronic Instrumentation","","",""
"uuid:2768f31d-1413-4129-b90a-ae20d4af6b4e","http://resolver.tudelft.nl/uuid:2768f31d-1413-4129-b90a-ae20d4af6b4e","Imaging Scheme for 3-D High-Frame-Rate Intracardiac Echography: A Simulation Study","Soozande, Mehdi (Erasmus MC); Ossenkoppele, B.W. (TU Delft ImPhys/Imaging Physics; TU Delft ImPhys/Medical Imaging); Hopf, Y.M. (TU Delft Electronic Instrumentation); Pertijs, M.A.P. (TU Delft Electronic Instrumentation); Verweij, M.D. (TU Delft ImPhys/Medical Imaging); de Jong, N. (TU Delft ImPhys/Medical Imaging); Vos, H.J. (Erasmus MC); Bosch, Johan G. (Erasmus MC)","","2022","Atrial fibrillation (AF) is the most common cardiac arrhythmia and is normally treated by RF ablation. Intracardiac echography (ICE) is widely employed during RF ablation procedures to guide the electrophysiologist in navigating the ablation catheter, although only 2-D probes are currently clinically used. A 3-D ICE catheter would not only improve visualization of the atrium and ablation catheter, but it might also provide the 3-D mapping of the electromechanical wave (EW) propagation pattern, which represents the mechanical response of cardiac tissue to electrical activity. The detection of this EW needs 3-D high-frame-rate imaging, which is generally only realizable in tradeoff with channel count and image quality. In this simulation-based study, we propose a high volume rate imaging scheme for a 3-D ICE probe design that employs 1-D micro-beamforming in the elevation direction. Such a probe can achieve a high frame rate while reducing the channel count sufficiently for realization in a 10-Fr catheter. To suppress the grating-lobe (GL) artifacts associated with micro-beamforming in the elevation direction, a limited number of fan-shaped beams with a wide azimuthal and narrow elevational opening angle are sequentially steered to insonify slices of the region of interest. An angular weighted averaging of reconstructed subvolumes further reduces the GL artifacts. We optimize the transmit beam divergence and central frequency based on the required image quality for EW imaging (EWI). Numerical simulation results show that a set of seven fan-shaped transmission beams can provide a frame rate of 1000 Hz and a sufficient spatial resolution to visualize the EW propagation on a large 3-D surface.","3-D intracardiac echography (ICE); data rate reduction; electromechanical wave imaging (EWI); high-frame-rate ultrasound imaging","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2023-07-01","","ImPhys/Imaging Physics","ImPhys/Medical Imaging","","",""
"uuid:2ba01344-3101-4d53-b334-72949327b4ab","http://resolver.tudelft.nl/uuid:2ba01344-3101-4d53-b334-72949327b4ab","Design of an ultrasound transceiver asic with a switching-artifact reduction technique for 3D carotid artery imaging","Kim, Taehoon (Student TU Delft); Fool, F. (TU Delft ImPhys/Medical Imaging); Simoes dos Santos, D. (TU Delft ImPhys/Medical Imaging); Chang, Z.Y. (TU Delft Electronic Instrumentation); Noothout, E.C. (TU Delft ImPhys/Medical Imaging); Vos, H.J. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Bosch, Johan G. (Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation)","","2021","This paper presents an ultrasound transceiver application-specific integrated circuit (ASIC) directly integrated with an array of 12 × 80 piezoelectric transducer elements to enable next-generation ultrasound probes for 3D carotid artery imaging. The ASIC, implemented in a 0.18 µm high-voltage Bipolar-CMOS-DMOS (HV BCD) process, adopted a programmable switch matrix that allowed selected transducer elements in each row to be connected to a transmit and receive channel of an imaging system. This made the probe operate like an electronically translatable linear array, allowing large-aperture matrix arrays to be interfaced with a manageable number of system channels. This paper presents a second-generation ASIC that employed an improved switch design to minimize clock feedthrough and charge-injection effects of high-voltage metal–oxide–semiconductor field-effect transistors (HV MOSFETs), which in the first-generation ASIC caused parasitic transmis-sions and associated imaging artifacts. The proposed switch controller, implemented with cascaded non-overlapping clock generators, generated control signals with improved timing to mitigate the effects of these non-idealities. Both simulation results and electrical measurements showed a 20 dB reduction of the switching artifacts. In addition, an acoustic pulse-echo measurement successfully demonstrated a 20 dB reduction of imaging artifacts.","3D ultrasound imaging; Charge injection; Clock feedthrough; High-voltage (HV) switches; Matrix transducers; Ultrasound application-specific integrated circuit (ASIC)","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:c9c53518-019d-465c-b7cb-97bd3bf5aec5","http://resolver.tudelft.nl/uuid:c9c53518-019d-465c-b7cb-97bd3bf5aec5","A Pitch-Matched Low-Noise Analog Front-End With Accurate Continuous Time-Gain Compensation for High-Density Ultrasound Transducer Arrays","Guo, P. (TU Delft Electronic Instrumentation); Chang, Z.Y. (TU Delft Electronic Instrumentation); Noothout, E.C. (TU Delft ImPhys/Medical Imaging); Vos, H.J. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Bosch, Johan G. (Erasmus MC); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation)","","2022","This article presents a compact analog front-end (AFE) circuit for ultrasound receivers with linear-in-dB continuous gain control for time-gain compensation (TGC). The AFE consists of two variable-gain stages, both of which employ a novel complementary current-steering network (CCSN) as the interpolator to realize continuously variable gain. The first stage is a trans-impedance amplifier (TIA) with a hardware-sharing inverter-based input stage to save power and area. The TIA's output couples capacitively to the second stage, which is a class-AB current amplifier (CA). The AFE is integrated into an application-specific integrated circuit (ASIC) in a 180-nm high-voltage BCD technology and assembled with a 100 μm-pitch PZT transducer array of 8 × 8 elements. Both electrical and acoustic measurements show that the AFE achieves a linear-in-dB gain error below ±0.4 dB within a 36-dB gain range, which is > 2 × better than the prior art. Per channel, the AFE occupies 0.025 mm2 area, consumes 0.8 mW power, and achieves an input-referred noise density of 1.31 pA/√Hz.","Application-specific integrated circuit (ASIC); Capacitors; Gain; Imaging; Interpolation; pitch-matched analog front-end (AFE); time-gain compensation (TGC); Trajectory; trans-impedance amplifier (TIA); Transducers; Ultrasonic imaging; ultrasound imaging; variable gain amplifier (VGA)","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2023-06-30","","","Electronic Instrumentation","","",""
"uuid:61a5c99c-9393-417c-9d94-a87659774486","http://resolver.tudelft.nl/uuid:61a5c99c-9393-417c-9d94-a87659774486","Multiline 3D beamforming using micro-beamformed datasets for pediatric transesophageal echocardiography","Bera, D. (Erasmus MC); Raghunathan, S.B. (TU Delft ImPhys/Acoustical Wavefield Imaging); Chen, C. (TU Delft Electronic Instrumentation); Chen, Z. (TU Delft Electronic Instrumentation); Pertijs, M.A.P. (TU Delft Electronic Instrumentation); Verweij, M.D. (TU Delft ImPhys/Acoustical Wavefield Imaging); Daeichin, V. (TU Delft ImPhys/Acoustical Wavefield Imaging); Vos, H.J. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Bosch, J.G. (Erasmus MC)","","2018","Until now, no matrix transducer has been realized for 3D transesophageal echocardiography (TEE) in pediatric patients. In 3D TEE with a matrix transducer, the biggest challenges are to connect a large number of elements to a standard ultrasound system, and to achieve a high volume rate (>200 Hz). To address these issues, we have recently developed a prototype miniaturized matrix transducer for pediatric patients with micro-beamforming and a small central transmitter. In this paper we propose two multiline parallel 3D beamforming techniques (μBF25 and μBF169) using the micro-beamformed datasets from 25 and 169 transmit events to achieve volume rates of 300 Hz and 44 Hz, respectively. Both the realizations use angle-weighted combination of the neighboring overlapping sub-volumes to avoid artifacts due to sharp intensity changes introduced by parallel beamforming. In simulation, the image quality in terms of the width of the point spread function (PSF), lateral shift invariance and mean clutter level for volumes produced by μBF25 and μBF169 are similar to the idealized beamforming using a conventional single-line acquisition with a fully-sampled matrix transducer (FS4k, 4225 transmit events). For completeness, we also investigated a 9 transmit-scheme (3 × 3) that allows even higher frame rates but found worse B-mode image quality with our probe. The simulations were experimentally verified by acquiring the μBF datasets from the prototype using a Verasonics V1 research ultrasound system. For both μBF169 and μBF25, the experimental PSFs were similar to the simulated PSFs, but in the experimental PSFs, the clutter level was ∼10 dB higher. Results indicate that the proposed multiline 3D beamforming techniques with the prototype matrix transducer are promising candidates for real-time pediatric 3D TEE.","matrix transducer; parallel beamforming; pediatric TEE; sub-array beamforming; transesophageal echocardiography","en","journal article","","","","","","Accepted author manuscript","","2020-03-29","","","ImPhys/Acoustical Wavefield Imaging","","",""
"uuid:679fb87d-5bb6-4455-b5e9-676da83e7420","http://resolver.tudelft.nl/uuid:679fb87d-5bb6-4455-b5e9-676da83e7420","An Ultrasound Matrix Transducer for High-Frame-Rate 3-D Intra-cardiac Echocardiography","Simoes dos Santos, D. (TU Delft ImPhys/Verweij group; TU Delft ImPhys/Medical Imaging); Ossenkoppele, B.W. (TU Delft ImPhys/Medical Imaging); Hopf, Y.M. (TU Delft Electronic Instrumentation); Soozande, Mehdi (Erasmus MC); Noothout, E.C. (TU Delft ImPhys/Verweij group); Vos, H.J. (TU Delft ImPhys/Verweij group; Erasmus MC); Bosch, Johan G. (Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; TU Delft ImPhys/Verweij group; Erasmus MC); de Jong, N. (TU Delft ImPhys/De Jong group; Erasmus MC)","","2024","Objective: Described here is the development of an ultrasound matrix transducer prototype for high-frame-rate 3-D intra-cardiac echocardiography. Methods: The matrix array consists of 16 × 18 lead zirconate titanate elements with a pitch of 160 µm × 160 µm built on top of an application-specific integrated circuit that generates transmission signals and digitizes the received signals. To reduce the number of cables in the catheter to a feasible number, we implement subarray beamforming and digitization in receive and use a combination of time-division multiplexing and pulse amplitude modulation data transmission, achieving an 18-fold reduction. The proposed imaging scheme employs seven fan-shaped diverging transmit beams operating at a pulse repetition frequency of 7.7 kHz to obtain a high frame rate. The performance of the prototype is characterized, and its functionality is fully verified. Results: The transducer exhibits a transmit efficiency of 28 Pa/V at 5 cm per element and a bandwidth of 60% in transmission. In receive, a dynamic range of 80 dB is measured with a minimum detectable pressure of 10 Pa per element. The element yield of the prototype is 98%, indicating the efficacy of the manufacturing process. The transducer is capable of imaging at a frame rate of up to 1000 volumes/s and is intended to cover a volume of 70° × 70° × 10 cm. Conclusion: These advanced imaging capabilities have the potential to support complex interventional procedures and enable full-volumetric flow, tissue, and electromechanical wave tracking in the heart.","Application-specific integrated circuit; High frame rate; Intra-cardiac echocardiography; Matrix array; Three-dimensional; Ultrasound transducer","en","journal article","","","","","","","","","","","ImPhys/Verweij group","","",""
"uuid:9998e466-617d-4a4b-a12a-13a813b4b621","http://resolver.tudelft.nl/uuid:9998e466-617d-4a4b-a12a-13a813b4b621","Impact of Bit Errors in Digitized RF Data on Ultrasound Image Quality","Chen, Z. (TU Delft Electronic Instrumentation); Soozande, M. (TU Delft ImPhys/Acoustical Wavefield Imaging); Vos, H.J. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Bosch, J.G. (TU Delft ImPhys/Acoustical Wavefield Imaging); Verweij, M.D. (TU Delft ImPhys/Acoustical Wavefield Imaging; TU Delft ImPhys/Medical Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation)","","2020","This article quantitatively analyzes the impact of bit errors in digitized RF data on ultrasound image quality. The quality of B-mode images in both linear array and phased array imaging is evaluated by means of three objective image quality metrics: peak signal-to-noise ratio, structural similarity index, and contrast-to-noise ratio, when bit errors are introduced to the RF data with different bit-error rates (BERs). The effectiveness of coding schemes for forward error detection and correction to improve the image quality is also studied. The results show that ultrasound imaging is inherently resilient to high BER. The image quality suffers unnoticeable degradation for BER lower than 1E-6. Simple 1-bit parity coding with 9% added redundancy helps to retain similar image quality for BER up to 1E-4, and Hamming coding with 33.3% added redundancy allows the BER to increase to 1E-3. These results can serve as a guideline in the datalink design for ultrasound probes with in-probe receive digitization. With much more relaxed BER requirements than in typical datalinks, the design can be optimized by allowing fewer cables with higher data rate per cable or lower power consumption with the same cable count.","In-probe digitizatio; datalink; forward error detection/correction (FEDC); image quality metrics (IQM); Bit error rate (BER)","en","journal article","","","","","","","","","","","Electronic Instrumentation","","",""
"uuid:34f73c81-fc73-4583-afc7-55ab99d38ada","http://resolver.tudelft.nl/uuid:34f73c81-fc73-4583-afc7-55ab99d38ada","Automatic Max-Likelihood Envelope Detection Algorithm for Quantitative High-Frame-Rate Ultrasound for Neonatal Brain Monitoring","Kortenbout, A.J. (Erasmus MC); Costerus, Sophie (Erasmus MC); Dudink, Jeroen (University Medical Center Utrecht); de Jong, N. (TU Delft ImPhys/Verweij group; Erasmus MC); de Graaff, Jurgen C. (Erasmus MC; Weill Cornell Medical College); Vos, H.J. (TU Delft ImPhys/Verweij group; Erasmus MC); Bosch, Johan G. (Erasmus MC)","","2024","Objective: Post-operative brain injury in neonates may result from disturbed cerebral perfusion, but accurate peri-operative monitoring is lacking. High-frame-rate (HFR) cerebral ultrasound could visualize and quantify flow in all detectable vessels using spectral Doppler; however, automated quantification in small vessels is challenging because of low signal amplitude. We have developed an automatic envelope detection algorithm for HFR pulsed wave spectral Doppler signals, enabling neonatal brain quantitative parameter maps during and after surgery. Methods: HFR ultrasound data from high-risk neonatal surgeries were recorded with a custom HFR mode (frame rate = 1000 Hz) on a Zonare ZS3 system. A pulsed wave Doppler spectrogram was calculated for each pixel containing blood flow in the image, and spectral peak velocity was tracked using a max-likelihood estimation algorithm of signal and noise regions in the spectrogram, where the most likely cross-over point marks the blood flow velocity. The resulting peak systolic velocity (PSV), end-diastolic velocity (EDV) and resistivity index (RI) were compared with other detection schemes, manual tracking and RIs from regular pulsed wave Doppler measurements in 10 neonates. Results: Envelope detection was successful in both high- and low-quality arterial and venous flow spectrograms. Our technique had the lowest root mean square error for EDV, PSV and RI (0.46 cm/s, 0.53 cm/s and 0.15, respectively) when compared with manual tracking. There was good agreement between the clinical pulsed wave Doppler RI and HFR measurement with a mean difference of 0.07. Conclusion: The max-likelihood algorithm is a promising approach to accurate, automated cerebral blood flow monitoring with HFR imaging in neonates.","Cerebral ultrasound; Envelope detection; High-frame-rate ultrasound; High-risk surgery; Max-likelihood; Monitoring; Neonates; Pulsed wave Doppler; Spectral Doppler","en","journal article","","","","","","","","","","","ImPhys/Verweij group","","",""
"uuid:d37c5259-3862-4faa-a177-f602c009d8fe","http://resolver.tudelft.nl/uuid:d37c5259-3862-4faa-a177-f602c009d8fe","Acoustic streaming-based calibration of ultrasound transducers","Simoes dos Santos, D. (TU Delft ImPhys/Verweij group; TU Delft ImPhys/Medical Imaging); Baldini, L.B. (TU Delft ImPhys/Verweij group); Vos, H.J. (TU Delft ImPhys/Verweij group; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; TU Delft ImPhys/Verweij group; Erasmus MC); de Jong, N. (TU Delft ImPhys/De Jong group; Erasmus MC); van Neer, P.L.M.J. (TU Delft ImPhys/Verweij group; TU Delft ImPhys/Medical Imaging; TNO)","","2024","The accurate determination of the transfer function of ultrasound transducers is important for their design and operational performance. However, conventional methods for quantifying the transfer function, such as hydrophone measurements, radiation force balance, and pulse-echo measurements, are costly and complex due to specialized equipment required. In this study, we introduce a novel approach to estimate the transfer function of ultrasound transducers by measuring the acoustic streaming velocity generated by the transducer. We utilize an experimental setup consisting of a water tank with a millimeter scale, an ink-filled syringe, and a camera for recording the streaming phenomenon. Through streaming velocity measurements in the frequency range from 2 to 8 MHz, we determined the transfer function of an unfocused circular transducer with a center frequency of 5 MHz and a radius of 5.6 mm. We compared the performance of our method with hydrophone and pulse-echo measurements. At the center frequency, we measured a transmit efficiency of 1.9 kPa/V using the streaming approach, while hydrophone and pulse-echo measurements yielded transmit efficiencies of 2.1 kPa/V and 1.8 kPa/V, respectively. These findings demonstrate that the proposed method for estimating the transfer function of ultrasound transducers achieves a sufficient level of accuracy comparable to pulse-echo and hydrophone measurements.","Acoustic streaming; Reciprocity; Safety; Sensitivity; Transfer function; Ultrasound transducer","en","journal article","","","","","","","","","","","ImPhys/Verweij group","","",""
"uuid:3f5330ea-f02b-4041-bbee-d9eab8f18a3e","http://resolver.tudelft.nl/uuid:3f5330ea-f02b-4041-bbee-d9eab8f18a3e","A Tiled Ultrasound Matrix Transducer for Volumetric Imaging of the Carotid Artery","Simoes dos Santos, D. (TU Delft ImPhys/Verweij group; TU Delft ImPhys/Medical Imaging); Fool, F. (TU Delft ImPhys/Verweij group); Mozaffarzadeh, M. (TU Delft ImPhys/Verweij group); Shabanimotlagh, M. (TU Delft ImPhys/Medical Imaging); Noothout, E.C. (TU Delft ImPhys/Verweij group); Kim, T. (TU Delft Electronic Instrumentation); Rozsa, N.N.M. (TU Delft Electronic Instrumentation); Vos, H.J. (TU Delft ImPhys/Verweij group; Erasmus MC); Bosch, Johan G. (Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; TU Delft ImPhys/Verweij group; Erasmus MC); de Jong, N. (TU Delft ImPhys/De Jong group; Erasmus MC)","","2022","High frame rate three-dimensional (3D) ultrasound imaging would offer excellent possibilities for the accurate assessment of carotid artery diseases. This calls for a matrix transducer with a large aperture and a vast number of elements. Such a matrix transducer should be interfaced with an application-specific integrated circuit (ASIC) for channel reduction. However, the fabrication of such a transducer integrated with one very large ASIC is very challenging and expensive. In this study, we develop a prototype matrix transducer mounted on top of multiple identical ASICs in a tiled configuration. The matrix was designed to have 7680 piezoelectric elements with a pitch of 300 μm × 150 μm integrated with an array of 8 × 1 tiled ASICs. The performance of the prototype is characterized by a series of measurements. The transducer exhibits a uniform behavior with the majority of the elements working within the −6 dB sensitivity range. In transmit, the individual elements show a center frequency of 7.5 MHz, a −6 dB bandwidth of 45%, and a transmit efficiency of 30 Pa/V at 200 mm. In receive, the dynamic range is 81 dB, and the minimum detectable pressure is 60 Pa per element. To demonstrate the imaging capabilities, we acquired 3D images using a commercial wire phantom.","application-specific integrated circuit (ASIC); carotid artery; high-frame rate; lead zirconate titanate (PZT); matrix array; three-dimensional (3D); ultrasound imaging; ultrasound transducer","en","journal article","","","","","","","","","","","ImPhys/Verweij group","","",""
"uuid:e2444d6c-5dc2-4532-8a21-5a874a41faca","http://resolver.tudelft.nl/uuid:e2444d6c-5dc2-4532-8a21-5a874a41faca","A 2D Ultrasound Transducer with Front-End ASIC and Low Cable Count for 3D Forward-Looking Intravascular Imaging: Performance and Characterization","Janjic, Jovana (Erasmus MC); Tan, M. (TU Delft Electronic Instrumentation); Daeichin, V. (TU Delft ImPhys/Acoustical Wavefield Imaging); Noothout, E.C. (TU Delft ImPhys/Acoustical Wavefield Imaging); Chen, C. (TU Delft Electronic Instrumentation); Chen, Z. (TU Delft Electronic Instrumentation); Chang, Z.Y. (TU Delft Electronic Instrumentation); Beurskens, Robert H.S.H. (Erasmus MC); van Soest, G. (Erasmus MC); van der Steen, A.F.W. (Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Acoustical Wavefield Imaging); Pertijs, M.A.P. (TU Delft Electronic Instrumentation); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging)","","2018","Intravascular ultrasound is an imaging modality used to visualize atherosclerosis from within the inner lumen of human arteries. Complex lesions like chronic total occlusions require forward-looking intravascular ultrasound (FL-IVUS), instead of the conventional side-looking geometry. Volumetric imaging can be achieved with 2D array transducers, which present major challenges in reducing cable count and device integration. In this work we present an 80-element lead zirconium titanate (PZT) matrix ultrasound transducer for FL-IVUS imaging with a front-end application-specific integrated circuit (ASIC) requiring only 4 cables. After investigating optimal transducer designs we fabricated the matrix transducer consisting of 16 transmit (TX) and 64 receive (RX) elements arranged on top of an ASIC having an outer diameter of 1.5 mm and a central hole of 0.5 mm for a guidewire. We modeled the transducer using finite element analysis and compared the simulation results to the values obtained through acoustic measurements. The TX elements showed uniform behavior with a center frequency of 14 MHz, a -3 dB bandwidth of 44 % and a transmit sensitivity of 0.4 kPa/V at 6 mm. The RX elements showed center frequency and bandwidth similar to the TX elements, with an estimated receive sensitivity of 3.7 μV/Pa. We successfully acquired a 3D FL image of three spherical reflectors in water using delay-and-sum beamforming and the coherence factor method. Full synthetic aperture acquisition can be achieved with frame rates on the order of 100 Hz. The acoustic characterization and the initial imaging results show the potential of the proposed transducer to achieve 3D FL-IVUS imaging.","Forward-looking; Front-end ASIC; Intravascular Ultrasound; piezo-electrical transducer","en","journal article","","","","","","","","","","","Electronic Instrumentation","","",""
"uuid:007f75b1-2263-49d9-aeb1-2f1f26cc4223","http://resolver.tudelft.nl/uuid:007f75b1-2263-49d9-aeb1-2f1f26cc4223","Fast Volumetric Imaging Using a Matrix Transesophageal Echocardiography Probe with Partitioned Transmit–Receive Array","Bera, D. (Erasmus MC); Van Den Adel, Franc (Oldelft Ultrasound); Radeljic-Jakic, Nikola (Oldelft Ultrasound); Lippe, Boris (Oldelft Ultrasound); Soozande, M. (Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation); Verweij, M.D. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Kruizinga, P. (Erasmus MC); Daeichin, V. (TU Delft ImPhys/Acoustical Wavefield Imaging); Vos, H.J. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); van der Steen, A.F.W. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Bosch, Johan G. (Erasmus MC); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC)","","2018","We describe a 3-D multiline parallel beamforming scheme for real-time volumetric ultrasound imaging using a prototype matrix transesophageal echocardiography probe with diagonally diced elements and separated transmit and receive arrays. The elements in the smaller rectangular transmit array are directly wired to the ultrasound system. The elements of the larger square receive aperture are grouped in 4 × 4-element sub-arrays by micro-beamforming in an application-specific integrated circuit. We propose a beamforming sequence with 85 transmit–receive events that exhibits good performance for a volume sector of 60° × 60°. The beamforming is validated using Field II simulations, phantom measurements and in vivo imaging. The proposed parallel beamforming achieves volume rates up to 59Hz and produces good-quality images by angle-weighted combination of overlapping sub-volumes. Point spread function, contrast ratio and contrast-to-noise ratio in the phantom experiment closely match those of the simulation. In vivo 3-D imaging at 22-Hz volume rate in a healthy adult pig clearly visualized the cardiac structures, including valve motion.","Transesophageal echocardiography; Matrix transducer; Sub-array beamforming; Parallel beamforming; Volumetric ultrasound imaging","en","journal article","","","","","","Accepted Author Manuscript","","2019-08-18","","","Electronic Instrumentation","","",""
"uuid:1e510e37-04e9-41f3-a872-67776fca97d4","http://resolver.tudelft.nl/uuid:1e510e37-04e9-41f3-a872-67776fca97d4","A Transceiver ASIC for a Single-Cable 64-Element Intra-Vascular Ultrasound Probe","van Willigen, D.M. (TU Delft Electronic Instrumentation); Kang, E. (Sony Semicondictor Solutions, Oslo); Janjic, Jovana (Johnson & Johnson); Noothout, E.C. (TU Delft ImPhys/Medical Imaging); Chang, Z.Y. (TU Delft Electronic Instrumentation); Verweij, M.D. (TU Delft ImPhys/Medical Imaging); de Jong, N. (TU Delft ImPhys/Medical Imaging); Pertijs, M.A.P. (TU Delft Electronic Instrumentation)","","2021","This article presents an application-specific integrated circuit (ASIC) designed for intra-vascular ultrasound imaging that interfaces 64 piezoelectric transducer elements to an imaging system using a single micro-coaxial cable. Thus, it allows a single-element transducer to be replaced by a transducer array to enable 3-D imaging. The 1.5-mm-diameter ASIC is intended to be mounted at the tip of a catheter, directly integrated with a 2-D array of piezoelectric transducer elements. For each of these elements, the ASIC contains a high-voltage (HV) switch, allowing the elements to transmit an acoustic wave in response to an HV pulse generated by the imaging system. A low-noise amplifier then amplifies the resulting echo signals and relays them as a signal current to the imaging system, while the same cable provides a 3-V supply. Element selection and other settings can be programmed by modulating configuration data on the supply, thus enabling full synthetic aperture imaging. An integrated element test mode measures the element capacitance to detect bad connections to the transducer elements. The ASIC has been fabricated in a 0.18- μm HV CMOS technology and consumes only 6 mW in receive. Electrical measurements show correct switching of 30-V transmit pulses and a receive amplification with a 71-dB dynamic range, including 12 dB of programmable gain over a 3-dB bandwidth of 21 MHz. The functionality of the ASIC has been successfully demonstrated in a 3-D imaging experiment.","Element test mode; front-end application-specific integrated circuit (ASIC); intra-vascular ultrasound (IVUS); single cable; transceiver ASIC; ultrasound","en","journal article","","","","","","","","","","","Electronic Instrumentation","","",""
"uuid:c1b93340-dee3-4082-9d57-e27a2accd60d","http://resolver.tudelft.nl/uuid:c1b93340-dee3-4082-9d57-e27a2accd60d","Suppression of Lamb wave excitation via aperture control of a transducer array for ultrasonic clamp-on flow metering","Massaad Mouawad, J.M. (TU Delft ImPhys/Medical Imaging); van Neer, P.L.M.J. (TU Delft ImPhys/Medical Imaging); Willigen, D. M. van (TNO); Pertijs, M.A.P. (TU Delft Electronic Instrumentation); de Jong, N. (TU Delft ImPhys/Medical Imaging); Verweij, M.D. (TU Delft ImPhys/Medical Imaging)","","2020","During ultrasonic clamp-on flow metering, Lamb waves propagating in the pipe wall may limit the measurement accuracy by introducing absolute errors in the flow estimates. Upon reception, these waves can interfere with the up and downstream waves refracting from the liquid, and disturb the measurement of the transit time difference that is used to obtain the flow speed. Thus, suppression of the generation of Lamb waves might directly increase the accuracy of a clamp-on flow meter. Existing techniques apply to flow meters with single element transducers. This paper considers the application of transducer arrays and presents a method to achieve a predefined amount of suppression of these spurious Lamb waves based on appropriate amplitude weightings of the transducer elements. Finite element simulations of an ultrasonic clamp-on flow measurement setting will be presented to show the effect of array aperture control on the suppression of the Lamb waves in a 1-mm-thick stainless steel pipe wall. Furthermore, a proof-of-principle experiment will be shown that demonstrates a good agreement with the simulations.","","en","journal article","","","","","","","","2021-05-01","","","ImPhys/Medical Imaging","","",""
"uuid:7421d172-a81e-446b-aedd-ec329f14f1e3","http://resolver.tudelft.nl/uuid:7421d172-a81e-446b-aedd-ec329f14f1e3","Design and Proof-of-Concept of a Matrix Transducer Array for Clamp-on Ultrasonic Flow Measurements","Massaad Mouawad, J.M. (TU Delft ImPhys/Medical Imaging); van Neer, P.L.M.J. (TU Delft ImPhys/Medical Imaging); van Willigen, D.M. (TU Delft Electronic Instrumentation); Noothout, E.C. (TU Delft ImPhys/Medical Imaging); de Jong, N. (TU Delft ImPhys/Medical Imaging); Pertijs, M.A.P. (TU Delft Electronic Instrumentation); Verweij, M.D. (TU Delft ImPhys/Medical Imaging)","","2022","Common clamp-on ultrasonic flow meters consist of two single-element transducers placed on the pipe wall. Flow speed is measured noninvasively, i.e., without interrupting the flow and without perforating the pipe wall, which also minimizes safety risks and avoids pressure drops inside the pipe. However, before metering, the transducers have to be carefully positioned along the pipe axis to correctly align the acoustic beams and obtain a well-calibrated flowmeter. This process is done manually, is dependent on the properties of the pipe and the liquid, does not account for pipe imperfections, and becomes troublesome on pipelines with an intricate shape. Matrix transducer arrays are suitable to dynamically steer acoustic beams and realize self-alignment upon reception, without user input. In this work, the design of a broadband 37×17 matrix array (center frequency of 1 MHz) to perform clamp-on ultrasonic flow measurements over a wide range of liquids (c=1000-2000m/s, α≤1 dB/MHz · cm) and pipe sizes is presented. Three critical aspects were assessed: efficiency, electronic beam steering, and wave mode conversion in the pipe wall. A prototype of a proof-of-concept flowmeter consisting of two 36-element linear arrays (center frequency of 1.1 MHz) was fabricated and placed on a 1-mm-thick, 40-mm inner diameter stainless steel pipe in a custom-made flow loop filled with water. At resonance, simulated and measured efficiencies in water of the linear arrays compared well: 0.88 and 0.81 kPa/V, respectively. Mean flow measurements were achieved by electronic beam steering of the acoustic beams and using both compressional and shear waves generated in the pipe wall. Correlation coefficients of R2>0.99 between measured and reference flow speeds were obtained, thus showing the operational concept of an array-based clamp-on ultrasonic flowmeter.","Acoustics; Beam steering; beam steering; Biomedical measurement; clamp-on flow meter; Guided waves; Liquids; Meters; transducer design; Ultrasonic transducer arrays; Ultrasonic variables measurement; ultrasound flow meter","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:d7438b91-9541-4622-b3ba-8b521020ed2d","http://resolver.tudelft.nl/uuid:d7438b91-9541-4622-b3ba-8b521020ed2d","A Reconfigurable Ultrasound Transceiver ASIC With 24 x 40 Elements for 3-D Carotid Artery Imaging","Kang, E. (TU Delft Electronic Instrumentation); Ding, Q. (TU Delft Electronic Instrumentation); Shabanimotlagh, M. (TU Delft ImPhys/Acoustical Wavefield Imaging); Kruizinga, P. (Erasmus MC); Chang, Z.Y. (TU Delft Electronic Instrumentation); Noothout, E.C. (TU Delft ImPhys/Acoustical Wavefield Imaging); Vos, H.J. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Bosch, J.W. (Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); de Jong, N. (TU Delft ImPhys/Acoustical Wavefield Imaging; Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation)","","2018","This paper presents an ultrasound transceiver application-specific integrated circuit (ASIC) designed for 3-D ultrasonic imaging of the carotid artery. This application calls for an array of thousands of ultrasonic transducer elements, far exceeding the number of channels of conventional imaging systems. The 3.6 x 6.8 mm² ASIC interfaces a piezo-electric transducer (PZT) array of 24 x 40 elements, directly integrated on top of the ASIC, to an imaging system using only 24 transmit and receive channels. Multiple ASICs can be tiled together to form an even bigger array. The ASIC, implemented in a 0.18 μm high-voltage (HV) BCD process, consists of a reconfigurable switch matrix and row-level receive circuits. Each element is associated with a compact bootstrapped HV transmit switch, an isolation switch for the receive circuits and programmable logic that enables a variety of imaging modes. Electrical and acoustic experiments successfully demonstrate the functionality of the ASIC. In addition, the ASIC has been successfully used in a 3-D imaging experiment.","3-D ultrasound imaging; high-voltage (HV) switches; matrix transducer; reconfigurability; ultrasound application-specific integrated circuit (ASIC).","en","journal article","","","","","","Accepted author manuscript","","","","","Electronic Instrumentation","","",""
"uuid:141385ee-1b0a-4976-bbe2-cf3b324c7825","http://resolver.tudelft.nl/uuid:141385ee-1b0a-4976-bbe2-cf3b324c7825","A Compact Integrated High-Voltage Pulser Insensitive to Supply Transients for 3-D Miniature Ultrasound Probes","Hopf, Y.M. (TU Delft Electronic Instrumentation); Ossenkoppele, B.W. (TU Delft ImPhys/Medical Imaging); Soozande, M. (Erasmus MC); Noothout, E.C. (TU Delft ImPhys/Medical Imaging); Chang, Z.Y. (TU Delft Electronic Instrumentation); Vos, H.J. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Bosch, Johan G. (Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Pertijs, M.A.P. (TU Delft Electronic Instrumentation)","","2022","class=""MsoNormal"">In this letter, a compact high-voltage (HV) transmit circuit for dense 2-D transducer arrays used in 3-D ultrasonic imaging systems is presented. Stringent area requirements are addressed by a unipolar pulser with embedded transmit/receive switch. Combined with a capacitive HV level shifter, it forms the ultrasonic HV transmit circuit with the lowest reported HV transistor count and area without any static power consumption. The balanced latched-based level shifter implementation makes the design insensitive to transients on the HV supply caused by pulsing, facilitating application in probes with limited local supply decoupling, such as imaging catheters. Favorable scaling through resource sharing benefits massively arrayed architectures while preserving full individual functionality. A prototype of 8 × 9 elements was fabricated in the TSMC 0.18 μm HV BCD technology and a 160μm×160μm PZT transducer matrix is manufactured on the chip. The system is designed to drive 65-V peak-to-peak pulses on 2-pF transducer capacitance and hardware sharing of six elements allows for an area of only 0.008 mm2 per element. Electrical characterization as well as acoustic results obtained with the 6-MHz central frequency transducer are demonstrated.","BCD technology; CMOS; high-voltage (HV) level shifter; high-voltage pulser; PZT transducer; supply transient; transmit/receive switching; ultrasound","en","journal article","","","","","","Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.","","2023-07-01","","","Electronic Instrumentation","","",""
"uuid:67458f43-ff64-4767-b9b9-acb0d9ac92d3","http://resolver.tudelft.nl/uuid:67458f43-ff64-4767-b9b9-acb0d9ac92d3","Algorithm to Correct Measurement Offsets Introduced by Inactive Elements of Transducer Arrays in Ultrasonic Flow Metering","Massaad Mouawad, J.M. (TU Delft ImPhys/Medical Imaging; KROHNE New Technologies BV); van Neer, P.L.M.J. (TU Delft ImPhys/Medical Imaging; TNO); van Willigen, D.M. (TU Delft Electronic Instrumentation; TNO); Pertijs, M.A.P. (TU Delft Electronic Instrumentation); de Jong, N. (TU Delft ImPhys/Medical Imaging; Erasmus MC); Verweij, M.D. (TU Delft ImPhys/Medical Imaging; Erasmus MC)","","2022","Ultrasonic flow meters (UFMs) based on transducer arrays offer several advantages. With electronic beam steering, it is possible to tune the steering angle of the beam for optimal signal-tonoise ratio (SNR) upon reception. Moreover, multiple beams can be generated to propagate through different travel paths, covering a wider section of the flow profile. Furthermore, in a clamp-on configuration, UFMs based on transducer arrays can perform self-calibration. In this manner, userinput is minimized and measurement repeatability is increased. In practice, transducer array elements may break down. This could happen due to aging, exposure to rough environments, and/or rough mechanical contact. As a consequence of inactive array elements, the measured transit time difference contains two offsets. One offset originates from non-uniform spatial sampling of the generated wavefield. Another offset originates from the ill-defined beam propagating through a travel path different from the intended one. In this paper, an algorithm is proposed that corrects for both of these offsets. The algorithm also performs a filtering operation in the frequency-wavenumber domain of all spurious (i.e., flow-insensitive) wave modes. The advantage of implementing the proposed algorithm is demonstrated on simulations and measurements, showing improved accuracy and precision of the transit time differences compared to the values obtained when the algorithm is not applied. The proposed algorithm can be implemented in both in-line and clamp-on configuration of UFMs based on transducer arrays.","guided waves; transducer arrays; ultrasonic flow meter","en","journal article","","","","","","","","","","","ImPhys/Medical Imaging","","",""
"uuid:05e4f501-6109-443f-8743-bc3cb5801eeb","http://resolver.tudelft.nl/uuid:05e4f501-6109-443f-8743-bc3cb5801eeb","Sensitive capacitive pressure sensors based on graphene membrane arrays","Siskins, M. (TU Delft QN/Steeneken Lab; Kavli institute of nanoscience Delft); Lee, M. (TU Delft QN/Steeneken Lab; Kavli institute of nanoscience Delft); Wehenkel, D. (Applied Nanolayers); van Rijn, R. (TU Delft EKL-Users; Applied Nanolayers); de Jong, Tijmen W. (Kavli institute of nanoscience Delft; Student TU Delft); Renshof, Johannes R. (Kavli institute of nanoscience Delft; Student TU Delft); Hopman, Berend C. (Kavli institute of nanoscience Delft; Student TU Delft); Peters, Willemijn S.J.M. (Kavli institute of nanoscience Delft; Student TU Delft); Davidovikj, D. (TU Delft QN/van der Zant Lab; TU Delft QN/Steeneken Lab; Kavli institute of nanoscience Delft); van der Zant, H.S.J. (TU Delft QN/van der Zant Lab; Kavli institute of nanoscience Delft); Steeneken, P.G. (TU Delft Dynamics of Micro and Nano Systems; TU Delft QN/Steeneken Lab; Kavli institute of nanoscience Delft)","","2020","The high flexibility, impermeability and strength of graphene membranes are key properties that can enable the next generation of nanomechanical sensors. However, for capacitive pressure sensors, the sensitivity offered by a single suspended graphene membrane is too small to compete with commercial sensors. Here, we realize highly sensitive capacitive pressure sensors consisting of arrays of nearly ten thousand small, freestanding double-layer graphene membranes. We fabricate large arrays of small-diameter membranes using a procedure that maintains the superior material and mechanical properties of graphene, even after high-temperature annealing. These sensors are readout using a low-cost battery-powered circuit board, with a responsivity of up to 47.8 aF Pa−1 mm−2, thereby outperforming the commercial sensors.","OA-Fund TU Delft","en","journal article","","","","","","","","","","","QN/Steeneken Lab","","",""
"uuid:55c96f13-c660-4777-a0fe-cd591602e905","http://resolver.tudelft.nl/uuid:55c96f13-c660-4777-a0fe-cd591602e905","Systems analysis and controlled malaria infection in Europeans and Africans elucidate naturally acquired immunity","de Jong, Sanne E. (Leiden University Medical Center); van Unen, Vincent (Leiden University Medical Center; Stanford University); Manurung, Mikhael D. (Leiden University Medical Center); Jochems, Simon P. (Leiden University Medical Center); Höllt, T. (TU Delft Computer Graphics and Visualisation; Leiden Computational Biology Center; Leiden University Medical Center); Pezzotti, N. (TU Delft Computer Graphics and Visualisation); Eisemann, E. (TU Delft Computer Graphics and Visualisation); Lelieveldt, B.P.F. (TU Delft Pattern Recognition and Bioinformatics; Leiden University Medical Center); Reinders, M.J.T. (TU Delft Pattern Recognition and Bioinformatics; Leiden University Medical Center; Delft Bioinformatics Lab)","","2021","Controlled human infections provide opportunities to study the interaction between the immune system and malaria parasites, which is essential for vaccine development. Here, we compared immune signatures of malaria-naive Europeans and of Africans with lifelong malaria exposure using mass cytometry, RNA sequencing and data integration, before and 5 and 11 days after venous inoculation with Plasmodium falciparum sporozoites. We observed differences in immune cell populations, antigen-specific responses and gene expression profiles between Europeans and Africans and among Africans with differing degrees of immunity. Before inoculation, an activated/differentiated state of both innate and adaptive cells, including elevated CD161+CD4+ T cells and interferon-γ production, predicted Africans capable of controlling parasitemia. After inoculation, the rapidity of the transcriptional response and clusters of CD4+ T cells, plasmacytoid dendritic cells and innate T cells were among the features distinguishing Africans capable of controlling parasitemia from susceptible individuals. These findings can guide the development of a vaccine effective in malaria-endemic regions.","","en","journal article","","","","","","","","","","","Computer Graphics and Visualisation","","",""
"uuid:3f9a5b71-0a5f-48b4-8eb7-183df27abd41","http://resolver.tudelft.nl/uuid:3f9a5b71-0a5f-48b4-8eb7-183df27abd41","Planning and developing a high-speed railway new town under state entrepreneurialism in China","Wang, B. (TU Delft Urban Development Management; Tsinghua University); de Jong, Martin (Erasmus Universiteit Rotterdam; Fudan University); van Bueren, Ellen (TU Delft Management in the Built Environment); Ersoy, A. (TU Delft Urban Development Management); Song, Yun (Erasmus Universiteit Rotterdam)","","2022","The development of high-speed railway (HSR) new towns in China represents a new phase of suburbanization and has had a significant impact on urban expansion, but not all of its mechanisms and drivers have been studied. This article aims to understand the booming development of HSR new towns in China through the theoretical lens of state entrepreneurialism. It dissects the entrepreneurial behaviors of the local state in a medium-sized city, which harnesses the HSR project strategically to develop a new town. Our findings reveal that local governments play out state entrepreneurialism in developing HSR new towns. They compete with other cities for HSR projects. They are motivated by land revenue generation, career advancement for officials, and maintaining state power. Furthermore, this article contributes to the understanding of interactions among multi-level governments. Local states in China can also exert influence on the policymaking and resource allocation of the national government.","China; HSR station areas; new towns; state entrepreneurialism","en","journal article","","","","","","","","","","Management in the Built Environment","Urban Development Management","","",""
"uuid:bf89da1d-0ef5-4ec6-b1d0-e39d4bfe3a99","http://resolver.tudelft.nl/uuid:bf89da1d-0ef5-4ec6-b1d0-e39d4bfe3a99","DeltaDTM: A global coastal digital terrain model","Pronk, M.J. (TU Delft Urban Data Science; Deltares); Hooijer, Aljosja (Deltares); Eilander, Dirk (Deltares); Haag, Arjen (Deltares); de Jong, Tjalling (Deltares); Vousdoukas, Michalis (University of the Aegean, Mytilene); Vernimmen, Ronald (Data for Sustainability, Axel); Ledoux, H. (TU Delft Urban Data Science); Eleveld, M.A. (TU Delft Mathematical Geodesy and Positioning; Deltares)","","2024","Coastal elevation data are essential for a wide variety of applications, such as coastal management, flood modelling, and adaptation planning. Low-lying coastal areas (found below 10 m +Mean Sea Level (MSL)) are at risk of future extreme water levels, subsidence and changing extreme weather patterns. However, current freely available elevation datasets are not sufficiently accurate to model these risks. We present DeltaDTM, a global coastal Digital Terrain Model (DTM) available in the public domain, with a horizontal spatial resolution of 1 arcsecond (∼30 m) and a vertical mean absolute error (MAE) of 0.45 m overall. DeltaDTM corrects CopernicusDEM with spaceborne lidar from the ICESat-2 and GEDI missions. Specifically, we correct the elevation bias in CopernicusDEM, apply filters to remove non-terrain cells, and fill the gaps using interpolation. Notably, our classification approach produces more accurate results than regression methods recently used by others to correct DEMs, that achieve an overall MAE of 0.72 m at best. We conclude that DeltaDTM will be a valuable resource for coastal flood impact modelling and other applications.","energy access; energy security; power distribution","en","journal article","","","","","","","","","","","Urban Data Science","","",""
"uuid:841d3ba6-0c9b-40f2-8e01-652d7b8c61d5","http://resolver.tudelft.nl/uuid:841d3ba6-0c9b-40f2-8e01-652d7b8c61d5","Corrosie van vliegtuigconstructies: Deel II: Figuren (Collegedictaat)","de Jong, H.F.","","1986","","","nl","lecture notes","Delft University of Technology","","","","","","","","Aerospace Engineering","","","","",""
"uuid:55f90480-ae7c-4797-bd01-943d5e5e3412","http://resolver.tudelft.nl/uuid:55f90480-ae7c-4797-bd01-943d5e5e3412","Corrosie van vliegtuigconstructies: Deel I: Tekst (Collegedictaat)","de Jong, H.F.","","1986","","","nl","lecture notes","Delft University of Technology","","","","","","","","Aerospace Engineering","","","","",""
"uuid:d36add06-9f5a-4b8d-bc2e-fceab620fa5b","http://resolver.tudelft.nl/uuid:d36add06-9f5a-4b8d-bc2e-fceab620fa5b","Onderdelenbeschikbaarheid en voorraadnauwkeurigheid bij NedTrain Services BV (summary)","de Jong, I.","","2004","","","","master thesis","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:124f8d3e-5088-428e-b90a-0e3d127cf337","http://resolver.tudelft.nl/uuid:124f8d3e-5088-428e-b90a-0e3d127cf337","Sustainable production at Ballast Nedam NV - more than just energy (summary)","de Jong, R.","","2011","","","","master thesis","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:523d1b41-4f45-4f68-a94c-f0c2dc74ac80","http://resolver.tudelft.nl/uuid:523d1b41-4f45-4f68-a94c-f0c2dc74ac80","Bow flare impact simulation on a 9000 t dwt general cargo vessel","de Jong, Gijsbert","","2001","","hydrodynamics","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:9b6f029b-c35e-482a-a5eb-a383a43eb66a","http://resolver.tudelft.nl/uuid:9b6f029b-c35e-482a-a5eb-a383a43eb66a","Feasibility of Sail Assistance for Commercial Vessels. Vergelijkingsstudie naar de toepassing van hulpzeilvoortstuwing op een vrachtschip","de Jong, M.; Struijk, G.; Vogels, R.; Voncken, C.","","2012","","hydrodynamics","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:10da146e-b550-421b-86f4-53afe9b83725","http://resolver.tudelft.nl/uuid:10da146e-b550-421b-86f4-53afe9b83725","Onderzoek naar de mogelijkheden van gecombineerd snijden en spuiten in zand","de Jong, P,","","1987","","","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:aef0d64e-f1a4-41fb-9dfd-b2009fab341c","http://resolver.tudelft.nl/uuid:aef0d64e-f1a4-41fb-9dfd-b2009fab341c","Dynamisch gedrag van grote STS containerkranen (summary)","de Jong, W.","","2006","","","","master thesis","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:92e4b78e-9847-4f97-8715-349631d643a1","http://resolver.tudelft.nl/uuid:92e4b78e-9847-4f97-8715-349631d643a1","A numerical trim variation study for ships operating in off-design conditions. The validation of RANS code results and the explanation of the physical effects of the flow around a hull subject to trim variation","de Jong, R.H.","van Terwisga, T.J.C. (mentor)","2015","","resistance & propulsion","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:f621f9b4-2ea6-4dac-ab6c-77c316469f8a","http://resolver.tudelft.nl/uuid:f621f9b4-2ea6-4dac-ab6c-77c316469f8a","Dynamisch gedrag van grote STS containerkranen","de Jong, W.","","2006","","","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:3e86db2a-4cc2-4ef1-8b1d-40caa1133733","http://resolver.tudelft.nl/uuid:3e86db2a-4cc2-4ef1-8b1d-40caa1133733","Ontwerp van een volledig elektrisch aangedreven containerspreader (summary)","de Jong, P.B.","","2006","","","","master thesis","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:9fd4e767-7510-4428-9d0d-559aff3d68c4","http://resolver.tudelft.nl/uuid:9fd4e767-7510-4428-9d0d-559aff3d68c4","""Schuine as""-meetbrug: verdere ontwikeling en ijking","Griffioen, D.J.; de Jong, E.J.J.","","1992","","","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:b8128fa0-7572-4320-a49b-35e3872d296b","http://resolver.tudelft.nl/uuid:b8128fa0-7572-4320-a49b-35e3872d296b","Gemechaniseerd palletiseren van eindprodukten in een fabriek van kleine huishoudelijke apparaten (summary)","de Jong, L.P.","","1986","","","","master thesis","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:8baed64c-f483-4490-a445-e484ccdca4c6","http://resolver.tudelft.nl/uuid:8baed64c-f483-4490-a445-e484ccdca4c6","Ontwerp van een containerkraan aan boord van een binnenvaartschip (summary)","de Jong, M.A.","","1997","","","","master thesis","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:e92d2957-8518-48ba-9d6d-4a9dd2c601e2","http://resolver.tudelft.nl/uuid:e92d2957-8518-48ba-9d6d-4a9dd2c601e2","Onderzoek naar grondstoftransport naar de Duitse staalindustrie met behulp van duwvaart","de Jong, M.","","2001","","","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:21a0f028-5330-4483-94af-0adf17318a93","http://resolver.tudelft.nl/uuid:21a0f028-5330-4483-94af-0adf17318a93","Bow flare impact simulation on a 9000 t dwt general cargo vessel, Part A: Literature Study, Part B: Main Report, Part C: Appendices","de Jong, Gijbert","","2001","","ship structure laboratory","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:ed0e256f-f1cd-4569-b1f9-26fa9e64ba22","http://resolver.tudelft.nl/uuid:ed0e256f-f1cd-4569-b1f9-26fa9e64ba22","Ontwerp van een volledig elektrisch aangedreven containerspreader (summary)","de Jong, P.B.","","2006","","","","master thesis","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:d352341f-db69-4980-bbe4-f84eb19faf46","http://resolver.tudelft.nl/uuid:d352341f-db69-4980-bbe4-f84eb19faf46","Determining the impacts of a human operated Multi Trailer System on Inter Terminal Transport performance; Het bepalen van de impacts van door mensen bestuurde Multi Trailers Systemen op de prestatie van een Inter Terminal Transport systeem","de Jong, R.A.","Corman, F. (mentor)","2016","","","","master thesis","","","","","","","","2018-08-10","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:4d872ebd-e634-4a8e-a92c-a2ddc497bb03","http://resolver.tudelft.nl/uuid:4d872ebd-e634-4a8e-a92c-a2ddc497bb03","Onderdelenbeschikbaarheid en voorraadnauwkeurigheid bij NedTrain Services BV","de Jong, I.","","2004","","","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:39702500-3d21-4c76-8135-634cd614cdad","http://resolver.tudelft.nl/uuid:39702500-3d21-4c76-8135-634cd614cdad","Transport op B.V. De Meteoor. Een toekomstvisie","de Jong, V.J.","","1997","","","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:d38e8a8d-c754-4612-8531-ba3475e11978","http://resolver.tudelft.nl/uuid:d38e8a8d-c754-4612-8531-ba3475e11978","Moored tanker roll motions from parametric excitation. Parametrische excitatie van de rolbeweging in zeegang. Rollrespons of parametrically unstable tankers","de Jong, J.H.","Gerritsma, J. (mentor)","1984","","hydrodynamics","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:30bf9ac4-bcf8-44ce-8330-6abefb7a50b9","http://resolver.tudelft.nl/uuid:30bf9ac4-bcf8-44ce-8330-6abefb7a50b9","""Drijvende Windturbines"". Ontwerp van een drijvende ondersteuning voor een windturbine inclusief de invloed van de verankering","de Jong, M.S.","","2009","","","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Design, Production and Operation","","",""
"uuid:fc2da7f9-c7ff-41a7-9815-453a8f935ca2","http://resolver.tudelft.nl/uuid:fc2da7f9-c7ff-41a7-9815-453a8f935ca2","Onderdelenbeschikbaarheid en voorraadnauwkeurigheid bij NedTrain Services BV (summary)","de Jong, I.","","2004","","","","master thesis","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:0b6ed494-3849-490b-9103-1e9449a70091","http://resolver.tudelft.nl/uuid:0b6ed494-3849-490b-9103-1e9449a70091","Sustainable production at Ballast Nedam NV - more than just energy (summary)","de Jong, R.","","2011","","","","master thesis","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:ab3acc5c-cfb7-4b7b-97da-6dda1a08121a","http://resolver.tudelft.nl/uuid:ab3acc5c-cfb7-4b7b-97da-6dda1a08121a","De uitvoering van een laboratorium onderzoek naar de mogelijkheden van gecombineerd snijden en spuiten in zand","de Jong, P.","","1988","","","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:dcb0a5e9-ff0f-482d-a67b-7b42ee72608e","http://resolver.tudelft.nl/uuid:dcb0a5e9-ff0f-482d-a67b-7b42ee72608e","The impact of a B-to-B container transferium on the sojourn time of inland container vessels","de Jong, S.D.","Duinkerken, M.B. (mentor)","2017","","","","master thesis","","","","","","","","2021-04-01","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:eb6f229a-6496-4824-98a3-d9eade3a1943","http://resolver.tudelft.nl/uuid:eb6f229a-6496-4824-98a3-d9eade3a1943","Onderzoek en ontwerpen van High Performance Containerkranen","de Jong, R.","","2004","","","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:99880036-e484-4a6e-8d4d-2c9ad2c18df9","http://resolver.tudelft.nl/uuid:99880036-e484-4a6e-8d4d-2c9ad2c18df9","Supplier 2010-Project","de Jong, Louise","","2001","","","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Design, Production and Operation","","",""
"uuid:ac108edd-caa2-42e9-9035-4d3a9526fcfc","http://resolver.tudelft.nl/uuid:ac108edd-caa2-42e9-9035-4d3a9526fcfc","Ontwerp van een volledig elektrisch aangedreven containerspreader","de Jong, P.B.","","2006","","","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:2953f904-b6a7-4f9a-9119-e738d5a319de","http://resolver.tudelft.nl/uuid:2953f904-b6a7-4f9a-9119-e738d5a319de","Ontwerp van een containerkraan aan boord van een binnenvaartschip (summary)","de Jong, M.A.","","1997","","","","master thesis","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:746dcf7d-ae77-4ba7-a69d-b3d895f3953a","http://resolver.tudelft.nl/uuid:746dcf7d-ae77-4ba7-a69d-b3d895f3953a","NIET INGELEVERD","de Jong, P.","","1986","","","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Offshore and Dredging Engineering","","",""
"uuid:8a90db10-7d19-4a40-8300-a3dea988b0a3","http://resolver.tudelft.nl/uuid:8a90db10-7d19-4a40-8300-a3dea988b0a3","Gemechaniseerd palletiseren van eindprodukten in een fabriek van kleine huishoudelijke apparaten","de Jong, L.P.","","1986","","","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:4202ba93-1507-476e-8ded-ad7b4117a7d2","http://resolver.tudelft.nl/uuid:4202ba93-1507-476e-8ded-ad7b4117a7d2","Sustainable production at Ballast Nedam NV - more than just energy","de Jong, R.","","2011","","","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:626999bd-a908-4cec-883c-710036bc8f94","http://resolver.tudelft.nl/uuid:626999bd-a908-4cec-883c-710036bc8f94","Een produktie optimalisatie van het gebruik van spuiters op de sleephopperzuiger "" VOLVOX DELTA""","de Jong, P.","","1988","","","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:63e688b5-743b-422e-9d34-d53c962ba2b7","http://resolver.tudelft.nl/uuid:63e688b5-743b-422e-9d34-d53c962ba2b7","Exploitatie van een indiksleepkop","de Jong, R.P.M.","","1986","","","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Offshore and Dredging Engineering","","",""
"uuid:00f41f4a-f2cd-4751-87e2-41a9cc4fc339","http://resolver.tudelft.nl/uuid:00f41f4a-f2cd-4751-87e2-41a9cc4fc339","Onderzoek naar grondstoftransport naar de Duitse staalindustrie met behulp van duwvaart (summary)","de Jong, M.","","2001","","","","master thesis","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:0a832c73-2156-4cb9-bffa-28c3b365f2d1","http://resolver.tudelft.nl/uuid:0a832c73-2156-4cb9-bffa-28c3b365f2d1","Ontwerp van een containerkraan aan boord van een binnenvaartschip","de Jong, M.A.","","1997","","","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:1938a72a-9f5d-4fa5-9b5c-6ea5a93b1a87","http://resolver.tudelft.nl/uuid:1938a72a-9f5d-4fa5-9b5c-6ea5a93b1a87","Supplier 2010 - Project","de Jong, L.","","2001","","ship design production and operation","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:25408cb6-f985-4e25-9604-137dd2141b4c","http://resolver.tudelft.nl/uuid:25408cb6-f985-4e25-9604-137dd2141b4c","Onderzoek en ontwerpen van High Performance Containerkranen (summary)","de Jong, R.","","2004","","","","master thesis","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:7d230275-9e2f-4d82-9831-6922fac0db7b","http://resolver.tudelft.nl/uuid:7d230275-9e2f-4d82-9831-6922fac0db7b","The dynamical behaviour of a Fokker 100 main landing gear during skid controlled braking","de Jong, E.J.J.","","1993","","","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:55c257fc-185c-4775-b5ab-a343dfb5ab83","http://resolver.tudelft.nl/uuid:55c257fc-185c-4775-b5ab-a343dfb5ab83","Topsides installation vessel Pieter Schelte design on the topside support structure","de Jong, M.J.; Timmerman, G.K.","Wolters, J. (mentor)","1988","","offshore","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Offshore and Dredging Engineering","","",""
"uuid:b7ffd476-6cb4-436b-85e9-cde6a5b852c2","http://resolver.tudelft.nl/uuid:b7ffd476-6cb4-436b-85e9-cde6a5b852c2","Investigation of nonlinearities in the superposition of ship motions by 6DOF forced oscillations","de Jong, Pepijn","Pinkster, J.A. (mentor)","2005","","hydrodynamics","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:12e95fdf-ee67-46e7-b558-88c20fb7c846","http://resolver.tudelft.nl/uuid:12e95fdf-ee67-46e7-b558-88c20fb7c846","Onderzoek naar grondstoftransport naar de Duitse staalindustrie met behulp van duwvaart (summary)","de Jong, M.","","2001","","","","master thesis","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:557a4987-07b5-4cd3-b3f8-231da030771d","http://resolver.tudelft.nl/uuid:557a4987-07b5-4cd3-b3f8-231da030771d","Enige opmerkingen over het gedrag van een sterk niet-lineair schip in enkelvoudige golven","de Jong, A.","Gerritsma, J. (mentor)","1972","","hydrodynamics","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Hydromechanics and Structures","","",""
"uuid:82c02fc6-5020-4bbd-bbf0-5949a00ae273","http://resolver.tudelft.nl/uuid:82c02fc6-5020-4bbd-bbf0-5949a00ae273","Onderzoek en ontwerpen van High Performance Containerkranen (summary)","de Jong, R.","","2004","","","","master thesis","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:b6970e28-923e-462a-9c39-c87edc6abcb8","http://resolver.tudelft.nl/uuid:b6970e28-923e-462a-9c39-c87edc6abcb8","Gemechaniseerd palletiseren van eindprodukten in een fabriek van kleine huishoudelijke apparaten (summary)","de Jong, L.P.","","1986","","","","master thesis","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:009df090-64a3-4624-a5f0-a13a93c493e9","http://resolver.tudelft.nl/uuid:009df090-64a3-4624-a5f0-a13a93c493e9","Capaciteitsverhoging bij de overslag van containers","de Jong, H.","","1974","","","","master thesis","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:01024ddb-1a53-4500-9384-bf431506f3cd","http://resolver.tudelft.nl/uuid:01024ddb-1a53-4500-9384-bf431506f3cd","Dynamisch gedrag van grote STS containerkranen (summary)","de Jong, W.","","2006","","","","master thesis","","","","","","","","","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:df35cdac-c8df-46e7-9c55-40b4048dcb29","http://resolver.tudelft.nl/uuid:df35cdac-c8df-46e7-9c55-40b4048dcb29","Ontwerp van een bij lage snelheid drie sporig en bij hoge snelheid als een sporige gedragend voertuig","de Jong, A.","","1984","","","","other","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Transport Engineering and Logistics","","",""
"uuid:f6c1de06-3d9b-45c2-9ad7-8d8d4e93523f","http://resolver.tudelft.nl/uuid:f6c1de06-3d9b-45c2-9ad7-8d8d4e93523f","Nieuw informatiesysteem voor zeescheepsreparatiewerven Nieuw informatiesysteem voor Informatiestromen","Hengst, S.; Dirkse, C.; van Marle, M.L.; Smits, P.G.; Jordan, C.J.L.; de Jong, J.P.A.; Bakker, J.; van Leeuwen, E.; Kuijer, M.M.R.","","1998","","scheepsbouw; produktieproces","","other","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Design, Production and Operation","","",""
"uuid:d6e50b80-25ce-49fe-88e0-0dce54aef73f","http://resolver.tudelft.nl/uuid:d6e50b80-25ce-49fe-88e0-0dce54aef73f","Report on design phase ""supplier 2010"" - project","de Jong, L.","","2001","","","","other","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Design, Production and Operation","","",""
"uuid:8a2b3ef6-c994-4a55-81ac-4bd9d5ad0d27","http://resolver.tudelft.nl/uuid:8a2b3ef6-c994-4a55-81ac-4bd9d5ad0d27","Literature survey ""supplier 2010"" - project","de Jong, L.","","2001","","","","other","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Design, Production and Operation","","",""
"uuid:8579ddea-e351-4011-852b-c5a31c3db1dc","http://resolver.tudelft.nl/uuid:8579ddea-e351-4011-852b-c5a31c3db1dc","Generator failures caused by synchronising torques","de Jong, W.; Robinson, J.K.","","1986","","transactions","","other","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","","","",""
"uuid:e56755ff-d307-4a8d-a9e9-fdd242a053d1","http://resolver.tudelft.nl/uuid:e56755ff-d307-4a8d-a9e9-fdd242a053d1","Report on design phase ""supplier 2010"" - project","de Jong, L.","","2001","","","","other","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Design, Production and Operation","","",""
"uuid:ddaace32-6ac9-472d-8b4e-0dcc8635a254","http://resolver.tudelft.nl/uuid:ddaace32-6ac9-472d-8b4e-0dcc8635a254","Report on innovations ""supplier 2010"" - project","de Jong, L.","","2001","","","","other","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Design, Production and Operation","","",""
"uuid:921db96b-e61a-4644-a71f-d36fe6464317","http://resolver.tudelft.nl/uuid:921db96b-e61a-4644-a71f-d36fe6464317","Een methode ter bepaling van het onderhoudsprogramma uit veiligheidsoogpunt voor systemen aan boord van een schip","de Jong, H.","","1990","","","","other","","","","","","","","2012-12-31","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Design, Production and Operation","","",""
"uuid:1f01eb9f-132e-45a1-9496-5a2038bb20b5","http://resolver.tudelft.nl/uuid:1f01eb9f-132e-45a1-9496-5a2038bb20b5","De ontwikkeling van een methodiek ter bepaling van het onderhoud: concept voor scheepsmachine-installatjes op basis van veiligheidscriteria","de Jong, H.","","1990","","","","other","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Design, Production and Operation","","",""
"uuid:7a5ec04e-ae3f-49d7-8a18-ccd7e15ecd3d","http://resolver.tudelft.nl/uuid:7a5ec04e-ae3f-49d7-8a18-ccd7e15ecd3d","Nieuwe opzet van informatiestromen Nieuwe opzet van informatiestromen","Hengst, S.; Dirkse, C.; van Marle, M.L.; Smits, P.G.; Jordan, C.J.L.; de Jong, J.P.A.; Bakker, J.; van Leeuwen, E.; Kuijer, M.M.R.","","1998","","Scheepswerf; produktieproces","","other","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Design, Production and Operation","","",""
"uuid:ce2f4279-eeae-42e5-aeca-364700f55cb3","http://resolver.tudelft.nl/uuid:ce2f4279-eeae-42e5-aeca-364700f55cb3","Huidige opzet van informatiestromen Huidige opzet van informatiestromen","Hengst, S.; Dirkse, C.; van Marle, M.L.; Smits, P.G.; Jordan, C.J.L.; de Jong, J.P.A.; Bakker, J.; van Leeuwen, E.; Kuijer, M.M.R.","","1998","","Scheepswerf; produktieproces","","other","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Design, Production and Operation","","",""
"uuid:6b1817c3-5070-4eea-85d1-6f4586591817","http://resolver.tudelft.nl/uuid:6b1817c3-5070-4eea-85d1-6f4586591817","Invoering informatiesysteem voor zeescheepsreparatiewerven Invoering informatiesysteem voor Informatiestromen","Hengst, S.; Dirkse, C.; van Marle, M.L.; Smits, P.G.; Jordan, C.J.L.; de Jong, J.P.A.; Bakker, J.; van Leeuwen, E.; Kuijer, M.M.R.","","1998","","scheepsbouw; produktieproces","","other","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Design, Production and Operation","","",""
"uuid:5d347343-e517-460f-9fb3-7608ba52e843","http://resolver.tudelft.nl/uuid:5d347343-e517-460f-9fb3-7608ba52e843","QUAESTOR/ECOTRANS - Variaties van een Containerbinnenvaartschip","Boonstra, H.; Dirkse, C.; Roeleveld, R.; de Jong, G.","","1998","","Quaestor; Ecotrans; container; binnenvaart; binnenvaartschip; variaties","","other","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Design, Production and Operation","","",""
"uuid:57def68d-6b42-4d62-8eae-9348ccc32c04","http://resolver.tudelft.nl/uuid:57def68d-6b42-4d62-8eae-9348ccc32c04","Bedrijfsverbetering Zeescheepsreparatie: Productiviteit in de scheepsreparatie, Deel 1 Waarnemingen","Hengst, S.; Dirkse, C.; Evers, P.; van der Velden, J.; de Jong, J.; Jordan, C.; Kuijer, M.; van Leeuwen, E.","","1998","","scheepswerf; produktieproces; reparatie; zeescheepsreparatie","","other","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Design, Production and Operation","","",""
"uuid:da7b27c7-1678-4e79-9fba-c80a1ba9f64c","http://resolver.tudelft.nl/uuid:da7b27c7-1678-4e79-9fba-c80a1ba9f64c","Literature survey ""supplier 2010"" - project","de Jong, L.","","2001","","","","other","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Design, Production and Operation","","",""
"uuid:b4b7fdff-135e-420c-ab47-a512e8e88786","http://resolver.tudelft.nl/uuid:b4b7fdff-135e-420c-ab47-a512e8e88786","Report on innovations ""supplier 2010"" - project","de Jong, L.","","2001","","","","other","","","","","","","","indefinite","Mechanical, Maritime and Materials Engineering","Marine and Transport Technology","Ship Design, Production and Operation","","",""
"uuid:614437a0-8bf4-4f66-aa96-c9b7d043785a","http://resolver.tudelft.nl/uuid:614437a0-8bf4-4f66-aa96-c9b7d043785a","Influential properties on mechanical degradation of densified torrefied biomass in large scale transportation and storage","Gilvari, H. (TU Delft Transport Engineering and Logistics); Karaca, Kadir (Student TU Delft); de Jong, W. (TU Delft Large Scale Energy Storage); Schott, D.L. (TU Delft Transport Engineering and Logistics)","","2018","The poster investigates the mechanical properties (Particle and bulk densities, compressive strength, bending strength, and the angle of repose) of a variety of torrefied and non-torrefied biomass pellets and shows the relationship between different properties. Moreover, a novel and quick method to determine the particle size distribution of cylindrical pellets based on image processing is introduced.","","en","poster","","","","","","","","","","","Transport Engineering and Logistics","","",""
"uuid:ad13b363-bbf6-43f6-9efa-1aba59f12c24","http://resolver.tudelft.nl/uuid:ad13b363-bbf6-43f6-9efa-1aba59f12c24","The effect of particle size distribution on the bulk thermal conductivity of biomass pellets","Gilvari, H. (TU Delft Transport Engineering and Logistics); Eijssen, Dirk (Student TU Delft); IJzermans, Kasper (Student TU Delft); Stolk, Maarten (Student TU Delft); Homsma, Thom (Student TU Delft); de Jong, W. (TU Delft Large Scale Energy Storage); Schott, D.L. (TU Delft Transport Engineering and Logistics)","","2018","The large-scale storage of biomass pellets is challenging due to health issues, material loss, and the risk of fire and explosions. The thermal conductivity is a material property which plays a key role in determining the self-heating properties of biomass. Meanwhile, understanding the thermal conductivity and the affecting factors help to better understand and reduce the risk of self-heating and fire explosions. This poster investigates the effect of particle size distribution and bulk density on the thermal conductivity of biomass pellets.","","en","poster","","","","","","","","","","","Transport Engineering and Logistics","","",""
"uuid:42be0fe0-3ca4-4172-bc72-115a4d0efe29","http://resolver.tudelft.nl/uuid:42be0fe0-3ca4-4172-bc72-115a4d0efe29","An empirical demand model for e commerce","de Bok, M.A. (TU Delft Transport and Planning; Significance); Eggers, Larissa (Significance); Thoen, Sebastiaan (Significance); de Jong, Gerard (Significance; ITS Leeds)","","2022","1. Overview and motivation
The emergence of e-commerce in the past decade and the surging growth during the pandemic, partially at the cost of in-store shopping, have reinforced the need for a better representation of this type of consumer demand and its effects in urban transportation studies (Reiffer et al, 2021). Since this is a recent development, conventional passenger transport models only model the personal mobility for in-store shopping. Standard modelling tools for large-scale demand forecasts for online and in-store shopping are limited. A proper representation of this demand segment first of all requires an estimate of e-commerce demand, and second the simulation of the delivery of the orders. Jaller and Pahwa (2020) developed both an econometric MNL model for in-store and online shopping and applied it to a synthetic population to estimate externalities of the alternatives. The econometric model explains the preferences for type of shopping but not the total level of product consumption, and the delivery of online orders is estimated on aggregate statistics. Other disaggregate simulation studies only focus on e-commerce demand, without considering the trade-off between online versus in-store shopping, such as Cheng et al (2021). In effect, online ordering may reduce physical movements of people to stores, while increasing the delivery of orders to people’s home addresses. This shift is taking place for many consumer products and groceries as well. Weltevreden and Rotem-Minaldi (2007) show early evidence that e-commerce ordering in the Netherlands increases freight transport, while personal travel decreases marginally. On the side of e-commerce deliveries, the simulation of urban freight transport is a well-studied topic in recent literature (Mommens et al, 2021; Hörl and Puchinger, 2021; Reiffer et al, 2021). However, modelling the demand side of e-commerce is often still minimal.
2. Methodology, results and main contributions
We present an empirical e-commerce demand model that is implemented in an urban freight simulator developed in the H2020 project HARMONY (Kamargianni et al, 2020). This new demand model for e-commerce is now a part of the simulator’s parcel module, which generates delivery tours based on the parcel demand by households and businesses. We estimated an ordered logit model with the demand for e-commerce shipments to households as the dependent variable, based on the assumption that one online order equals one parcel, as a function of personal and household characteristics which are known within the simulator.
A second model, connecting e-commerce with the demand for traditional in-store shopping, is also presented here, albeit not yet implemented in the urban freight simulator. In this model we first estimated total consumer demand separately for groceries and non-groceries, and next an adoption model for e-commerce services. The model has the structure of a two-step logit model: an ordered logit model for the total consumer demand, and next a binary choice model for the choice between online and in-store shopping for each of the shopping occurrences that make up a person’s consumer demand.
The models are estimated on the Mobility Panel Netherlands, the MPN (Hoogendoorn-Lanser et al, 2015). The 2017 wave of the MPN contained additional questions regarding online and in-store shopping that can be used for the estimation of choice models. To make the models suitable for application in the freight simulator, we focused on explanatory variables that differ between locations (i.e., zones in a model). The most important variables in the choice models that explain the spatial pattern of e-commerce demand are household income, age of the respondent (in 10 categories) and urbanization level at household location. Other personal characteristics that do not vary spatially are included if they improve the explanatory power of the models (e.g., gender).
3. Conclusion and future works
Age and household income are important predictors for the adoption of e-commerce and the number of parcels ordered. The age-classes 18-39 have the highest preference for e-commerce ordering. Above 40, the preference for e-commerce steadily declines. Persons living in households in the highest income classes (more than 67,000€ per year) are the most likely adopters of online ordering for both groceries and non-groceries. The urbanization level does not affect the adoption of e-commerce services for non-groceries, but strongly for groceries. This can be explained by the limited availability of e-groceries in less urbanized areas, especially at the time of data collection in 2017.
The presented e-commerce demand model has been implemented in the HARMONY Tactical Freight Simulator where it is used to calculate the number of parcels delivered in an area, the subsequent delivery tours and their effects on traffic and emissions. As the explanatory variables differ between zones, we obtain spatially distinct effects. In a next step, the presented model can be linked to a passenger simulator to jointly model and assess the generation of shopping trips and parcel deliveries. Another important research topic is the formulation of representative growth scenarios for e-commerce demand. As online ordering adoption rates evolve over the coming decade, socio-economic developments alone will likely not be sufficient to explain them. Adequately representing the evolution of these adoption rates in transport models requires a tailored calibration approach.
The results of this research are presented in four steps, aligning with the four tasks to design an accommodation strategy (DAS steps): (step 1) assessing the campus anno 2016, compared to 2006 and clarified with historical background, (step 2) exploring changing demand, based on developments in society and higher education, (step 3) generating future models, derived from ten campus trends and (step 4) defining strategic choices for Campus NL and their functional, financial and physical consequences for universities.
This research report covers subjects like the changing academic place to learn and work, the total costs of (campus) ownership and sustainable campus ambitions.","","nl","report","TU Delft, Architecture, Management in the Built Environment","978-94-92516-38-1","","","","","","","","","Real Estate Management","","",""
"uuid:40f09247-c706-442e-94cf-a87eabfa59e9","http://resolver.tudelft.nl/uuid:40f09247-c706-442e-94cf-a87eabfa59e9","GPU Implementation of the RRB-solver","de Jong, M.A. (TU Delft Numerical Analysis); Vuik, Cornelis (TU Delft Numerical Analysis)","","2016","br","","en","report","Delft University of Technology","","","","","","","","","","Numerical Analysis","","",""
"uuid:c65dba35-9203-4842-9905-bf3391978cf0","http://resolver.tudelft.nl/uuid:c65dba35-9203-4842-9905-bf3391978cf0","The practice of Adaptive Delta Management in the Netherlands","de Jong, A.M.P. (Student TU Delft); de Vries, G. (TU Delft Organisation & Governance); Timmermans, Jos (TU Delft Policy Analysis)","","2021","In 2011, Adaptive Delta Management (ADM) was introduced in the Dutch Delta Program as a policy development method that incorporates uncertainty in decision-making. At this moment, little is known about the functioning of ADM in practice, while this is key for successful adaptation. This paper presents the results of research into the implementation of ADM in The Netherlands. We focus especially on the efficacy of ADM in dealing with uncertain sea-level rise.
This research concludes that to enhance adaptation to sea-level rise to keep the Netherlands safe, policymakers at all levels must gain an overview of the entire solution space over time. Furthermore, actors implementing adaptation plans, like water boards and municipalities, require more insight into the combined consequences of sea-level rise and national adaptation strategies for their area. Here we propose the development of regional consequence scenarios as a promising way forward. In addition, implementing actors need to be enabled to incorporate uncertainties in their decision-making processes. Especially they need support in using the sometimes complicated instruments of ADM.","","en","report","Flow Platform","","","","","","","","","","Organisation & Governance","","",""
"uuid:b771f0a9-f59c-44e7-bbe9-aeb79ac100ef","http://resolver.tudelft.nl/uuid:b771f0a9-f59c-44e7-bbe9-aeb79ac100ef","The Geopolitical Impact of Climate Mitigation Policies: How hydrocarbon exporting rentier states and developing nations can prepare for a more sustainable future","de Jong, Sijbren (The Hague Centre for Strategic Studies); Auping, Willem L. (TU Delft Policy Analysis); Oosterveld, Willem (The Hague Centre for Strategic Studies); Usanov, Artur (The Hague Centre for Strategic Studies); Abdalla, Mercedes (The Hague Centre for Strategic Studies); Van de Bovenkamp, Alice (The Hague Centre for Strategic Studies); Frattina della Frattina, Christopher (The Hague Centre for Strategic Studies)","","2017","","","en","report","The Hague Centre for Strategic Studies","978-94-92102-55-3","","","","","","","","","Policy Analysis","","",""
"uuid:8f760c9e-dd2f-48ad-8c3b-9696ced1fd5e","http://resolver.tudelft.nl/uuid:8f760c9e-dd2f-48ad-8c3b-9696ced1fd5e","Gebruik en effecten Wet voorkeursrecht gemeenten","de Wolff, H.W. (TU Delft Urban Development Management); de Greef, JH; Groetelaers, D.A. (TU Delft Support Architecture); de Jong, J.; Korthals Altes, W.K. (TU Delft Urban Development Management)","","2000","In juli 1996 is de gewijzigde Wet voorkeursrecht gemeenten (Wvg) in werking getreden. De wijziging maakt het mogelijk dat een groot aantal gemeenten een voorkeursrecht kan vestigen voor te realiseren uitbreidingslocaties.
Bij de wetswijziging is bepaald dat binnen vier jaar na inwerkingtreding van de wet de minister aan de Tweede Kamer een verslag zendt over de doeltreffendheid en de effecten van de wet in de praktijk. Het hieraan ten grondslag liggende evaluatieonderzoek is gesplitst in twee fasen; in de eerste helft van 1998 heeft vooronderzoek plaatsgevonden naar de eerste ervaringen met de Wvg en is in het verlengde hiervan een aanzet gegeven voor de aanpak van het evaluatieonderzoek.
Dit evaluatieonderzoek is, in opdracht van de Rijksplanologische Dienst, van december 1999 tot april 2000 uitgevoerd door de sectie Geo-informatie en Grondbeleid van de afdeling Geodesie van de TU Delft. Van dit onderzoek wordt in dit rapport deels verslag gedaan. In een tweede rapport wordt met name ingegaan op aanbevelingen naar aanleiding van de in kaart gebrachte effecten in het evaluatie-onderzoek.","","nl","report","Delft University Press","9040720835","","","","","","","","","Urban Development Management","","",""
"uuid:fc7efa35-58a8-4939-aade-4a14ddcdbf81","http://resolver.tudelft.nl/uuid:fc7efa35-58a8-4939-aade-4a14ddcdbf81","Berekening van roosters en orthotrope platen: Deel 1 en deel 2","de Jong, H.","","1985","","Stevin Laboratorium","nl","report","","","","","","","","","Civil Engineering and Geosciences","Structural Engineering","","","",""
"uuid:1fdbc9af-83b0-4ba3-9521-ece0ad0c8002","http://resolver.tudelft.nl/uuid:1fdbc9af-83b0-4ba3-9521-ece0ad0c8002","Quality parameters relevant for densification of bio-materials: Measuring methods and affecting factors - A review","Gilvari, H. (TU Delft Transport Engineering and Logistics); de Jong, W. (TU Delft Large Scale Energy Storage); Schott, D.L. (TU Delft Transport Engineering and Logistics)","","2019","Densification has been carried out for many years, mostly in biomass processing, animal feed production, and pharmaceutical industries. During the years, researchers and engineers attempted to improve the product quality and minimize the production costs. The most important quality parameters of solid bio-materials are the compressive strength, abrasion resistance, impact resistance, moisture adsorption, and density. Various studies used different standard and non-standard methods to characterize these quality parameters. The objective of this paper is twofold: (1) to investigate the state-of-the-art methods and devices used in the quality assessment of densified bio-materials, including a comparison between non-standard and standard methods. (2) to discuss the effect of different factors on the properties of densified bio-materials using an integrated approach. The results show a lack of standard methods for the quality assessment of bio-materials and therefore, there is an emerging need for development of dedicated standards for bio-materials. Moreover, the use of dissimilar methods and devices in the quality assessment of bio-materials gives risk to uncertainties about the effect of different factors on the product quality.","Bio-material; Densification; Density; Durability; Standard methods; Strength","en","review","","","","","","","","","","","Transport Engineering and Logistics","","",""
"uuid:8c9419f7-b084-4fc0-bea4-ddb7882195d1","http://resolver.tudelft.nl/uuid:8c9419f7-b084-4fc0-bea4-ddb7882195d1","How robust is the circular economy in Europe? An ascendency analysis with Eurostat data between 2010 and 2018","Zisopoulos, Filippos K. (Erasmus Universiteit Rotterdam); Schraven, D.F.J. (TU Delft Integral Design & Management); de Jong, Martin (Erasmus Universiteit Rotterdam; Fudan University)","","2022","Considering its relatively low circularity rate (11.8% in 2019), the EU set several waste management targets as part of its roadmap to a circular economy yet the decision about which transition pathway to follow is not trivial. The maximization of circularity in human made systems is intended to function as a catalyst for this transition albeit at the risk of establishing fragile techno-economic systems. To provide insights for a balanced transition to a circular economy its link with the ecological concepts of “resilience” and “robustness” is illuminated by assessing the theoretical robustness of the material and energy flow networks of the EU27 countries between 2010-2018 using Eurostat data. Results show that despite the high degrees of order (efficiencies) which all European countries developed over the years studied, none of them achieved near-maximum robustness. The identified relationships between the average circularity rate and the average energy efficiency with the theoretical robustness of these material and energy flow networks (for the years studied), respectively, suggest that ascendency analysis is a credible tool for supporting policy making. Both on a national and on a local level for developing circular and robust urban waste management systems given data availability. The contribution to the underlying theory of ascendency analysis is the introduction of the concepts of “technological boundaries” and “windows of efficiency” of these human-made networks which are juxtaposed with the “window of vitality” that is often used to describe healthy natural ecosystems. Finally, the limitations of ascendency analysis and directions for future research are presented.","Ascendency analysis; Circular economy; Ecological boundaries; European Union; Technological boundaries; Waste hierarchy; Window of efficiency; Window of vitality","en","review","","","","","","","","","","","Integral Design & Management","","",""