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The AccelerAge framework: a new statistical approach to predict biological age based on time-to-event data

Sluiskes, Marije (author), Goeman, Jelle (author), Beekman, Marian (author), Slagboom, Eline (author), van den Akker, E.B. (author), Putter, H. (author), Rodríguez-Girondo, Mar (author)

Aging is a multifaceted and intricate physiological process characterized by a gradual decline in functional capacity, leading to increased susceptibility to diseases and mortality. While chronological age serves as a strong risk factor for age-related health conditions, considerable heterogeneity exists in the aging trajectories of...

journal article 2024

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Faithful Model Explanations through Energy-Constrained Conformal Counterfactuals

Altmeyer, P. (author), Farmanbar, Mojtaba (author), van Deursen, A. (author), Liem, C.C.S. (author)

Counterfactual explanations offer an intuitive and straightforward way to explain black-box models and offer algorithmic recourse to individuals. To address the need for plausible explanations, existing work has primarily relied on surrogate models to learn how the input data is distributed. This effectively reallocates the task of learning...

journal article 2024

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Data implementation matters: Effect of software choice and LCI database evolution on a comparative LCA study of permanent magnets

Miranda Xicotencatl, Brenda (author), Kleijn, René (author), van Nielen, Sander (author), Donati, Franco (author), Sprecher, Benjamin (author), Tukker, Arnold (author)

Life cycle assessment (LCA) databases and software evolve. We analyzed to which extent software and evolving life cycle inventory databases affect the comparison of technology alternatives, using a comparative LCA on permanent magnets as a case study, with two selected software tools: CMLCA and Brightway LCA. We migrated the system models...

journal article 2023

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Crystal Growth and Physical Properties of Hybrid CoSn-YCo₆Ge₆ Structure Type Ln_xCo₃(Ge_1-ySn_y)₃ (Ln = Y, Gd)

Bravo, Moisés (author), McCandless, Gregory T. (author), Baumbach, Ryan E. (author), Wang, Y. (author), Ali, M.N. (author), Chan, Julia Y. (author)

There is an ongoing interest in kagome materials because they offer tunable platforms at the intersection of magnetism and electron correlation. Herein, we examine single crystals of new kagome materials, LnxCo3(Ge1-ySny)3 (Ln = Y, Gd; y = 0.11, 0.133), which were produced using the Sn flux-growth method. Unlike many of the related chemical...

journal article 2023

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Design of a syringe extension device (Chloe SED®) for low-resource settings in sub-Saharan Africa: a circular economy approach

Samenjo, K.T. (author), Ramanathan, Aparna (author), Gwer, Stephen Otieno (author), Bailey, Robert C. (author), Otieno, Fredrick Odhiambo (author), Koksal, Erin (author), Sprecher, Benjamin (author), Price, R.A. (author), Bakker, C.A. (author), Diehl, J.C. (author)

Underfunded healthcare infrastructures in low-resource settings in sub-Saharan Africa have resulted in a lack of medical devices crucial to provide healthcare for all. A representative example of this scenario is medical devices to administer paracervical blocks during gynaecological procedures. Devices needed for this procedure are usually...

journal article 2023

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Goal Ontology for Personalized Learning and Its Implementation in Child's Health Self-Management Support

Rijgersberg, R.M. (author), Vught, Willeke van (author), Broekens, D.J. (author), Neerincx, M.A. (author)

Intelligent tutoring systems need a model of learning goals for the personalization of educational content, tailoring of the learning path, progress monitoring, and adaptive feedback. This article presents such a model and corresponding interaction designs for the coaches and learners (respectively, a monitor-and-control dashboard and mobile...

journal article 2023

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Assessment of cyclic deformation behaviour of wire arc additively manufactured carbon steel

Mendez-Morales, Mariela (author), Branco, Ricardo (author), Tankova, T. (author), Rebelo, Carlos (author)

Wire Arc Additive Manufacturing (WAAM) has gained popularity due to its speed and cost-effectiveness. However, the current knowledge on the cyclic deformation behaviour of WAAM materials is limited. To address this issue, this study investigates the cyclic deformation behaviour of WAAM ER70S-6 carbon steel. Coupons were extracted from printed...

journal article 2024

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Optical STEM detection for scanning electron microscopy

Kievits, A.J. (author), Duinkerken, B. H.Peter (author), Fermie, Job (author), Lane, R. (author), Giepmans, Ben N.G. (author), Hoogenboom, J.P. (author)

Recent advances in electron microscopy techniques have led to a significant scale up in volumetric imaging of biological tissue. The throughput of electron microscopes, however, remains a limiting factor for the volume that can be imaged in high resolution within reasonable time. Faster detection methods will improve throughput. Here, we have...

journal article 2024

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Applied anthropometry for common industrial settings design: Working and ideal manual handling heights

Castellucci, Héctor (author), Viviani, Carlos (author), Arezes, Pedro (author), Molenbroek, J.F.M. (author), Martínez, Marta (author), Aparici, Verónica (author), Dianat, I. (author)

Anthropometry has been used extensively for designing safe and sustainable products and workplaces. However, it is common that designers need straightforward guidelines and dimensions, which they often lack, for specific design situations. Anthropometric data are usually presented in tables that summarize percentile values, separated by...

journal article 2020

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The 2021 flood event in the Dutch Meuse and tributaries from a hydraulic and morphological perspective

Strijker, B. (author), Asselman, Nathalie (author), de Jong, Jurjen (author), Barneveld, Hermjan (author)

In July of 2021, large areas in the catchment of the Meuse River in Belgium, the Netherlands and Germany were affected by extreme rainfall and floods. This paper presents the hydraulic and morphological data that were collected during and after the flood. The data were analysed to understand the hydraulic and morphological functioning of the...

journal article 2023

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Accuracy Assessment of Numerical Morphological Models Based on Reduced Saint-Venant Equations

Barneveld, H.J. (author), Mosselman, E. (author), Chavarrías, V. (author), Hoitink, A.J.F. (author)

Sustainable river management often requires long-term morphological simulations. As the future is unknown, uncertainty needs to be accounted for, which may require probabilistic simulations covering a large parameter domain. Even for one-dimensional models, simulation times can be long. One of the acceleration strategies is simplification of...

journal article 2024

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Exploring plastic transport dynamics in the Odaw river, Ghana

Pinto, Rose Boahemaa (author), Barendse, Tom (author), van Emmerik, Tim (author), van der Ploeg, Martine (author), Annor, F.O. (author), Duah, Kwame (author), Udo, Job (author), Uijlenhoet, R. (author)

Plastic pollution in rivers threatens ecosystems, increases flood risk due to its accumulations at hydraulic structures and its final emissions into the ocean threaten aquatic life, especially and probably most in coastal urbanized areas. Previous work suggests that plastic pollution in these urban rivers is influenced by hydrometeorological...

journal article 2023

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A 3D time-dependent backward erosion piping model

Pol, J.C. (author), Noordam, Aron (author), Kanning, W. (author)

Backward erosion piping (BEP) is a failure mechanism of hydraulic structures like dams and levees on cohesionless foundations subjected to seepage flows. This article models the time-dependent development of BEP using numerical simulation of the erosion process. A 3-dimensional finite element equilibrium BEP model is extended with a...

journal article 2024

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Level of match between facial dimensions of Chilean workers and respirator fit test panels proposed by LANL and NIOSH

Rodríguez, Ariel Antonio (author), Escanilla, David Eduardo (author), Caroca, Luis Alberto (author), Albornoz, Christian Eduardo (author), Marshall, Paulina Andrea (author), Molenbroek, J.F.M. (author), Castellucci, Héctor Ignacio (author)

The facial fit of respirators is crucial for determining how effectively respirators may protect users from exposure to airborne contaminants, when their use is required in the workplace. In the Chilean market, all the respirators available have been designed and manufactured using foreign regulations. The aim of this research was to...

journal article 2020

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Performance of flood defences in the Netherlands during the 2021 summer floods

Koelewijn, André (author), Pol, J.C. (author), van Schaijk, Malou (author)

During the July 2021 Flood, the main flood defences along the River Meuse in the Netherlands performed well and did not breach. This paper is meant to document the various incidents on the flood defence system. As such, it provides an overview and description of the reported incidents related to flood defences, including a few breaches in minor...

journal article 2023

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A machine learning approach to the design of customized shoe lasts

Booth, Brian G. (author), Sijbers, Jan (author), Huysmans, T. (author)

journal article 2019

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Variable-width contouring for additive manufacturing

Hornus, Samuel (author), Kuipers, T. (author), Devillers, Olivier (author), Teillaud, Monique (author), Martínez, Jonàs (author), Glisse, Marc (author), Lazard, Sylvain (author), Lefebvre, Sylvain (author)

In most layered additive manufacturing processes, a tool solidifies or deposits material while following pre-planned trajectories to form solid beads. Many interesting problems arise in this context, among which one concerns the planning of trajectories for filling a planar shape as densely as possible. This is the problem we tackle in the...

journal article 2020

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Experience From the 2021 Floods in the Netherlands: Household Survey Results on Impacts and Responses

Endendijk, Thijs (author), Botzen, W.J. Wouter (author), de Moel, Hans (author), Aerts, Jeroen C.J.H. (author), Duijndam, Sem J. (author), Slager, Kymo (author), Kolen, B. (author), Kok, M. (author)

This study provides an overview of the impact of the 2021 Summer floods in the Netherlands and the assessment of the effectiveness of various adaptation measures, evacuation strategies, and their impact on society. The floods were characterized by record rainfall in the cross-border region of the Meuse and Rhine basins and resulted in...

journal article 2023

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Educational level and its relationship with body height and popliteal height in Chilean male workers

Viviani, C. (author), Castellucci, H. I. (author), Arezes, P.M. (author), Bartsch, Angelo (author), Bragança, S. (author), Molenbroek, J.F.M. (author), Martínez, Marta (author), Aparici, V. (author)

A secular trend in body height has been experienced in many nations and populations, hypothesized to be the result of better living conditions. Educational level has been shown to be closely associated with body height. This study examined the changes in body height and popliteal height in a group of adult Chilean male workers by age cohort and...

journal article 2019

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Electronic assistive technology for community-dwelling solo-living older adults: A systematic review

Song, Y. (author), van der Cammen, T.J.M. (author)

The proportion of older adults who live alone in single households is growing continuously. In the care of these solo-living older adults, electronic assistive technology (EAT) can play an important role. The objective of this review is to investigate the effects of EAT on the wellbeing of community-dwelling older adults living alone in...

journal article 2019