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Van der Stok, J. (author), Koolen, M.K.E. (author), De Maat, M.P.M. (author), Amin Yavari, S. (author), Alblas, J. (author), Patka, P. (author), Verhaar, J.A.N. (author), Van Lieshout, E.E.M. (author), Zadpoor, A.A. (author), Weinans, H.H. (author), Jahr, H. (author)Regeneration of load-bearing segmental bone defects is a major challenge in trauma and orthopaedic surgery. The ideal bone graft substitute is a biomaterial that provides immediate mechanical stability, while stimulating bone regeneration to completely bridge defects over a short period. Therefore, selective laser melted porous titanium,...journal article 2015
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Poldervaart, M.T. (author), Wang, H. (author), Van der Stok, J. (author), Weinans, H.H. (author), Leeuwenburgh, S.C.G. (author), Cumhur Öner, F. (author), Dhert, W.J.A. (author), Alblas, J. (author)The design of bioactive three-dimensional (3D) scaffolds is a major focus in bone tissue engineering. Incorporation of growth factors into bioprinted scaffolds offers many new possibilities regarding both biological and architectural properties of the scaffolds. This study investigates whether the sustained release of bone morphogenetic protein...journal article 2013
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Van der Stok, J. (author), Wang, H. (author), Yavari, S.A. (author), Siebelt, M. (author), Sandker, M. (author), Waarsing, J.H. (author), Verhaar, J.A.N. (author), Jahr, H. (author), Zadpoor, A.A. (author), Leeuwenburgh, S.C.G. (author), Weinans, H. (author)Porous titanium scaffolds are a promising class of biomaterials for grafting large bone defects, because titanium provides sufficient mechanical support, whereas its porous structure allows bone ingrowth resulting in good osseointegration. To reinforce porous titanium scaffolds with biological cues that enhance and continue bone regeneration,...journal article 2013