Searched for: author:"Amin, Najaf"
(1 - 2 of 2)
document
van der Lee, Sven J. (author), Roshchupkin, Gennady V. (author), Adams, Hieab H. (author), Schmidt, Helena (author), Hofer, Edith (author), Saba, Yasaman (author), Schmidt, Reinhold (author), Hofman, Albert (author), Amin, Najaf (author), van Duijn, Cornelia M. (author), Vernooij, Meike W. (author), Ikram, Mohammad A. (author), Niessen, W.J. (author)
Background: The combination of genetics and imaging has improved their understanding of the brain through studies of aggregate measures obtained from high-resolution structural imaging. Voxel-wise analyses have the potential to provide more detailed information of genetic influences on the brain. Here they report a large-scale study of the...
journal article 2017
document
Holstege, H. (author), van der Lee, S.J. (author), Hulsman, M. (author), Hang Wong, Tsz (author), van Rooij, Jeroen (author), Weiss, Marjan M. (author), Louwersheimer, Eva (author), Wolters, Frank J, (author), Amin, Najaf (author), Reinders, M.J.T. (author), More Authors (author)
Accumulating evidence suggests that genetic variants in the SORL1 gene are associated with Alzheimer disease (AD), but a strategy to identify which variants are pathogenic is lacking. In a discovery sample of 115 SORL1 variants detected in 1908 Dutch AD cases and controls, we identified the variant characteristics associated with SORL1...
journal article 2017