Searched for: author%3A%22Androulakis%2C+Ioannis%22
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Androulakis, Ioannis (author), Ferrero, Riccardo (author), van Oossanen, R. (author), Manzin, Alessandra (author), Denkova, A.G. (author), Djanashvili, K. (author), Nadar, R.A. (author), van Rhoon, G.C. (author)
While hyperthermia has been shown to induce a variety of cytotoxic and sensitizing effects on cancer tissues, the thermal dose–effect relationship is still not well quantified, and it is still unclear how it can be optimally combined with other treatment modalities. Additionally, it is speculated that different methods of applying...
journal article 2023
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Androulakis, Ioannis (author), Mestrom, Rob M.C. (author), Christianen, Miranda E.M.C. (author), Kolkman‐deurloo, Inger Karine K. (author), van Rhoon, G.C. (author)
The combination of interstitial hyperthermia treatment (IHT) with high dose rate brachytherapy (HDR‐BT) can improve clinical outcomes since it highly enhances the efficiency of cell kill, especially when applied simultaneously. Therefore, we have developed the ThermoBrachy applicators. To effectively apply optimal targeted IHT, treatment...
journal article 2022
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Androulakis, Ioannis (author), Mestrom, Rob M.C. (author), Christianen, Miranda E.M.C. (author), Kolkman-Deurloo, Inger Karine K. (author), van Rhoon, G.C. (author)
In high-dose-rate brachytherapy (HDR-BT) for prostate cancer treatment, interstitial hyperthermia (IHT) is applied to sensitize the tumor to the radiation (RT) dose, aiming at a more efficient treatment. Simultaneous application of HDR-BT and IHT is anticipated to provide maximum radiosensitization of the tumor. With this rationale, the...
journal article 2022
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Ferrero, Riccardo (author), Androulakis, Ioannis (author), Martino, Luca (author), Nadar, R.A. (author), van Rhoon, G.C. (author), Manzin, Alessandra (author)
The evaluation of the biological effects of therapeutic hyperthermia in oncology and the precise quantification of thermal dose, when heating is coupled with radiotherapy or chemotherapy, are active fields of research. The reliable measurement of hyperthermia effects on cells and tissues requires a strong control of the delivered power and of...
journal article 2022
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Androulakis, Ioannis (author), Sumser, Kemal (author), Machielse, Melanie N.D. (author), Koppert, Linetta (author), Jager, Agnes (author), Nout, Remi (author), Franckena, Martine (author), van Rhoon, G.C. (author), Curto, Sergio (author)
Objective: The addition of hyperthermia in the treatment of intact breast cancer with the aim to improve local response is currently in a research phase. First, optimal hyperthermia devices need to be developed, for which a diverse, anatomically and pathologically accurate set of patient models is necessary. Methods: To investigate the...
journal article 2022
Searched for: author%3A%22Androulakis%2C+Ioannis%22
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