Searched for: author%3A%22Burla%2C+Federica%22
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van Dam, Eliane P. (author), Giubertoni, Giulia (author), Burla, Federica (author), Koenderink, G.H. (author), Bakker, Huib J. (author)
We study the relation between the macroscopic viscoelastic properties of aqueous hyaluronan polymer solutions and the molecular-scale dynamics of water using rheology measurements, differential dynamic microscopy, and polarization-resolved infrared pump-probe spectroscopy. We observe that the addition of hyaluronan to water leads to a slowing...
journal article 2020
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Vos, Bart E. (author), Martinez Torres, C.E. (author), Burla, Federica (author), Weisel, John W. (author), Koenderink, G.H. (author)
Fibrin is an elastomeric protein forming highly extensible fiber networks that provide the scaffold of blood clots. Here we reveal the molecular mechanisms that explain the large extensibility of fibrin networks by performing in situ small angle X-ray scattering measurements while applying a shear deformation. We simultaneously measure shear...
journal article 2020
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Burla, Federica (author), Sentjabrskaja, Tatjana (author), Pletikapic, Galja (author), Van Beugen, Joey (author), Koenderink, G.H. (author)
Hyaluronic acid is an abundant polyelectrolyte in the human body that forms extracellular hydrogels in connective tissues. It is essential for regulating tissue biomechanics and cell-cell communication, yet hyaluronan overexpression is associated with pathological situations such as cancer and multiple sclerosis. Due to its enormous molecular...
journal article 2020
document
Giubertoni, Giulia (author), Burla, Federica (author), Bakker, Huib J. (author), Koenderink, G.H. (author)
Many biopolymer hydrogels are environmentally responsive because they are held together by physical associations that depend on pH and temperature. Here, we investigate how the pH and temperature responses of the rheology of hyaluronan hydrogels are connected to the underlying molecular interactions. Hyaluronan is an essential structural...
journal article 2020
document
Fanalista, F. (author), Birnie, A.T.F. (author), Maan, R. (author), Burla, Federica (author), Charles usagé Charles-Carty, K.V. (author), Pawlik, G. (author), Deshpande, S.R. (author), Koenderink, Gijsje H. (author), Dogterom, A.M. (author), Dekker, C. (author)
Bottom-up biology is an expanding research field that aims to understand the mechanisms underlying biological processes via in vitro assembly of their essential components in synthetic cells. As encapsulation and controlled manipulation of these elements is a crucial step in the recreation of such cell-like objects, microfluidics is...
journal article 2019
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