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Dias Ribeiro de Carvalho, V.I. (author), Prabudiansyah, I. (author), Kovacik, Lubomir (author), Chami, Mohamed (author), Kieffer, R.Y. (author), van der Valk, R.A. (author), De Lange, Nick (author), Engel, Andreas (author), Aubin-Tam, M.E. (author)
AAA+ proteases are degradation machines that use ATP hydrolysis to unfold protein substrates and translocate them through a central pore toward a degradation chamber. FtsH, a bacterial membrane-anchored AAA+ protease, plays a vital role in membrane protein quality control. How substrates reach the FtsH central pore is an open key question...
journal article 2020