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Rácz, E. (author), Kurek, D. (author), Kant, M. (author), Baerveldt, E.M. (author), Florencia, E. (author), Mourits, S. (author), De Ridder, D. (author), Laman, J.D. (author), Van der Fits, L. (author), Prens, E.P. (author)
Psoriasis is characterized by hyperproliferation of keratinocytes and by infiltration of activated Th1 and Th17 cells in the (epi)dermis. By expression microarray, we previously found the GATA3 transcription factor significantly downregulated in lesional psoriatic skin. Since GATA3 serves as a key switch in both epidermal and T helper cell...
journal article 2011