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Saccher, M. (author), Kawasaki, S. (author), Klootwijk, Johan (author), van Schaijk, Rob (author), Dekker, R. (author)Recently, the applications of ultrasound transducers expanded from high-end diagnostic tools to point of care diagnostic devices and wireless power receivers for implantable devices. These new applications additionally require that the transducer technology must comply to biocompatibility and manufacturing scalability. In this respect,...journal article 2023
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Li, Jian (author), Li, Chenhui (author), Henneken, Vincent (author), Louwerse, Marcus (author), Van Rens, Jeannet (author), Dijkstra, Paul (author), Raz, Oded (author), Dekker, R. (author)The digitization of smart catheters will dramatically increase the demand for reliable and high data transmission in the distal tips. Optical fiber is a good candidate to provide high-speed data transmission. However, the extremely small size of the smart catheter tip, with less than a few millimeters in diameter, hampers the integration of...journal article 2022
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Saccher, M. (author), Kawasaki, S. (author), Proietti Onori, Martina (author), van Woerden, Geeske M. (author), Giagka, Vasiliki (author), Dekker, R. (author)Background<br/>Microelectrode arrays (MEA) enable the measurement and stimulation of the electrical activity of cultured cells. The integration of other neuromodulation methods will significantly enhance the application range of MEAs to study their effects on neurons. A neuromodulation method that is recently gaining more attention is focused...journal article 2022
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Kawasaki, S. (author), Yeh, Jia-Jun (author), Saccher, M. (author), Li, Jian (author), Dekker, R. (author)The main limitation of acoustic particle separation for microfluidic application is its low sorting efficiency. This is due to the weak coupling of surface acoustic waves (SAWs) into the microchannel. In this work, we demonstrate bulk acoustic wave (BAW) particle sorting using capacitive micromachined ultrasonic transducers (CMUTs) for the first...conference paper 2022
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Chakrabarty, Sanjiban (author), Quiros Solano, W.F. (author), Kuijten, Maayke M.P. (author), Haspels, Ben (author), Mallya, Sandeep (author), van de Stolpe, Anja (author), Odijk, Hanny (author), van Weerden, Wytske M. (author), Dekker, R. (author)Optimal treatment of cancer requires diagnostic methods to facilitate therapy choice and prevent ineffective treatments. Direct assessment of therapy response in viable tumor specimens could fill this diagnostic gap. Therefore, we designed a microfluidic platform for assessment of patient treatment response using tumor tissue slices under...journal article 2022
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Fayezioghani, A. (author), Dekker, R. (author), Sluys, Lambertus J. (author)Corrosion is a phenomenon observed in structural components in corrosive environments such as pipelines, bridges, aircrafts, turbines, etc. The computational model of corrosion should enjoy two features: a) accurately considering the electrochemistry of corrosion and b) properly dealing with the moving interface between solid and electrolyte....journal article 2022
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Fayezioghani, A. (author), Dekker, R. (author), Sluys, Lambertus J. (author)Structural components in corrosive environments such as pipelines, bridges, aircrafts, and turbines are imposed to stress corrosion. A stress corrosion model for pit growth should a) accurately consider the electrochemistry of the corrosion process, b) properly deal with the moving interface between solid and electrolyte, and c) effectively...journal article 2022
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Saccher, M. (author), Lolla, Sai Sandeep (author), Kawasaki, S. (author), Dekker, R. (author)Ultrasound (US) has recently gained attention for powering and communication with implantable devices due to its short wavelength and low attenuation. However, beam mis-alignments cause a sharp decrease in the amount of transferred power and quality of communication. This work investigates a telemetry protocol that relies on the difference in...conference paper 2022
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Dekker, R. (author)The world is currently in a severe man-made climate crisis, creating the need for using renewable energy sources such as offshore wind farms. Offshore wind turbines do not take up any valuable space on land and can use the greater wind resource at sea. The downside is, however, that they are exposed to a much harsher environment at sea, which...doctoral thesis 2021
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Saccher, M. (author), Kawasaki, S. (author), Dekker, R. (author)Recently, focused ultrasound has been proposed to power deeply implanted medical devices. Almost exclusively, lead zirconate titanate (PZT) transducers are used to convert acoustic energy into electrical energy. Unfortunately, these lead containing devices cannot be hermetically encapsulated since that would block the ultrasound. We propose the...conference paper 2021
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Kawasaki, S. (author), Subramaniam, Indulakshmi (author), Saccher, M. (author), Dekker, R. (author)Implantable medical devices are becoming smaller and more deeply implanted in the human body for various applications (i.e., neurostimulation, drug delivery, bone fracture monitoring). Therefore, an efficient ultrasound power transfer link is needed to charge these devices. However, this is challenging because each ultrasound transducer has...conference paper 2021
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Martins Da Ponte, R. (author), Gaio, N. (author), van Zeijl, H.W. (author), Vollebregt, S. (author), Dijkstra, Paul (author), Dekker, R. (author), Serdijn, W.A. (author), Giagka, Vasiliki (author)One of the many applications of organ-on-a-chip (OOC) technology is the study of biological processes in human induced pluripotent stem cells (iPSCs) during pharmacological drug screening. It is of paramount importance to construct OOCs equipped with highly compact in situ sensors that can accurately monitor, in real time, the extracellular...journal article 2021
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Dekker, R. (author), van der Meer, F.P. (author), Maljaars, Johan (author), Sluys, Lambertus J. (author)A numerical model for corrosion pit propagation under mechanical loading is presented. The level set method is used for corrosion front tracking and also enables the domain to be split into a solid and a pit domain. In the pit the diffusion of atoms originating from the dissolution process occurring at the pit front is simulated. The model is...journal article 2021
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Kluba, M.M. (author), Li, J. (author), Parkkinen, Katja (author), Louwerse, Marcus (author), Snijder, Jaap (author), Dekker, R. (author)Several Silicon on Insulator (SOI) wafer manufacturers are now offering products with customer‐defined cavities etched in the handle wafer, which significantly simplifies the fabrication of MEMS devices such as pressure sensors. This paper presents a novel cavity buried oxide (BOX) SOI substrate (cavity‐BOX) that contains a patterned BOX...journal article 2021
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Kawasaki, S. (author), Dijkema, E. (author), Saccher, M. (author), Giagka, Vasiliki (author), Schleipen, J.J.H.B. (author), Dekker, R. (author)In the bioelectronic medicine field, vagus nerve stimulation (VNS) is a promising technique that is expected to treat numerous inflammatory conditions, in addition to the currently FDA approved treatment for epilepsy, depression and obesity [1]. However, current VNS techniques are still limited in the spatial resolution that they can achieve,...conference paper 2021
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Kawasaki, S. (author), Westhoek, Y. (author), Subramaniam, I. (author), Saccher, M. (author), Dekker, R. (author)Using ultrasound to power deeply implanted biomedical devices is a promising technique due to its low attenuation in body tissue and its short wavelength that allows precise focusing of the energy. Ultrasound energy harvesting conventionally has been done using lead zirconate titanate (PZT) ultrasound transducers, which uses the piezoelectric...conference paper 2021
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Mastrangeli, Massimo (author), Aydogmus, H. (author), Dostanic, M. (author), Motreuil-Ragot, P.A. (author), Revyn, N. (author), de Wagenaar, B. (author), Dekker, R. (author), Sarro, Pasqualina M (author)Stemming from the convergence of tissue engineering and microfluidics, organ-on-chip (OoC) technology can reproduce in vivo-like dynamic microphysiological environments for tissues in vitro. The possibility afforded by OoC devices of realistic recapitulation of tissue and organ (patho)physiology may hold the key to bridge the current...conference paper 2021
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Dekker, R. (author), van der Meer, F.P. (author), Maljaars, J. (author), Sluys, Lambertus J. (author)This study presents calibration and validation of a cohesive extended finite element model for fatigue crack propagation in ductile materials. The approach relies on a separation between plasticity around the crack tip and fatigue crack growth at the crack tip such that the influence of plasticity on fatigue driving forces is predicted. This...journal article 2021
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Bakhshaee Babaroud, N. (author), Dekker, R. (author), Serdijn, W.A. (author), Giagka, Vasiliki (author)Parylene-C has been used as a substrate and encapsulation material for many implantable medical devices. However, to ensure the flexibility required in some applications, minimize tissue reaction, and protect parylene from degradation in vivo an additional outmost layer of polydimethylsiloxane (PDMS) is desired. In such a scenario, the adhesion...conference paper 2020
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Waafi, Affan K. (author), Gaio, N. (author), Quiros Solano, W.F. (author), Dijkstra, Paul (author), Sarro, Pasqualina M (author), Dekker, R. (author)We present the first Organ-on-Chip equipped with a low-impedance Poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) MicroElectrode Array (MEA). The novel device allows simultaneous mechanical stimulation with a stretchable PDMS membrane and electrical monitoring via the PEDOT:PSS MEA of multiple in vitro cell cultures. The...journal article 2020